Updated on 2026/08/08

写真a

 
SHINODA AKARI
 
Organization
Faculty of Environmental, Life, Natural Science and Technology Special-Appointment Assistant Professor
Position
Special-Appointment Assistant Professor
External link

Research Interests

  • 土壌微生物

  • エアロゾル

  • モンゴル国

  • 腸内細菌

  • 発酵乳製品

  • 菌叢解析

  • 微生物学

Education

  • Kyushu University   大学院生物資源環境科学府   生命機能科学科 博士課程

    2021.4 - 2024.3

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    Notes: 博士後期課程

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  • Kyushu University   大学院生物資源環境科学府   生命機能科学科 修士課程

    2019.4 - 2021.3

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    Country: Japan

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  • 辻日本料理マスターカレッジ    

    2018.4 - 2019.4

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  • Tokyo University of Agriculture   応用生物科学部   醸造科学科

    2013.4 - 2018.3

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    Country: Japan

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Research History

  • Okayama University   Faculty of Environmental, Life, Natural Science and Technology   Assistant professor

    2026.4

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    Country:Japan

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  • Nagoya University   Graduate School of Environmental Studies   Postdoctoral researcher

    2026.1 - 2026.3

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    Country:Japan

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  • Leibniz Institute for Natural Product Research and Infection Biology Hans Knöll Institute   Paleobiotechnology department   Postdoctoral researcher

    2024.4 - 2025.12

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    Country:Germany

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  • Max Planck Institute for Evolutionary Anthropology, Max-Planck-Institut für evolutionäre Anthropologie   Microbiome group   Visiting researcher

    2024.4 - 2025.12

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    Country:Germany

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  • Japan Society for the Promotion of Science

    2022.4 - 2024.3

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Professional Memberships

Committee Memberships

  • 生物工学若手会   プログラム・学生企画担当  

    2024.1 - 2024.6   

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  • JSBBA West 5th Student Forum   committee chairman  

    2022.9 - 2022.11   

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  • JSBBA West 4th Student Forum   committee member  

    2021.10 - 2021.11   

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Papers

  • Molecular mechanisms of complex-type N-glycan breakdown and metabolism by the human intestinal bacterium Barnesiella intestinihominis Reviewed

    Kanako Doi, Kazuki Mori, Misaki Komatsu, Akari Shinoda, Kosuke Tashiro, Yujiro Higuchi, Jiro Nakayama, Kaoru Takegawa

    Journal of Bioscience and Bioengineering   139 ( 1 )   14 - 22   2025.1

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    Publishing type:Research paper (scientific journal)   Publisher:Elsevier BV  

    DOI: 10.1016/j.jbiosc.2024.10.006

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  • Impact of container type on the microbiome of airag, a Mongolian fermented mare’s milk Reviewed

    Akari SHINODA, Yuri KOGA, Ryouta TSUCHIYA, Bat-Oyun TSERENPUREV, Badgar BATTSETSEG, Yuki MORINAGA, Jiro NAKAYAMA

    Bioscience of Microbiota, Food and Health   44 ( 1 )   90 - 99   2025

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)   Publisher:BMFH Press  

    DOI: 10.12938/bmfh.2024-023

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  • Gut microbiome signatures associated with type 2 diabetes in obesity in Mongolia Reviewed

    Akari Shinoda, Tsogtbaatar Lkhagvajav, Riko Mishima, Phatthanaphong Therdtatha, Dugersuren Jamiyan, Chantsaldulam Purevdorj, Sainbileg Sonomtseren, Battogtokh Chimeddorj, Bira Namdag, Yuan Kun Lee, Shirchin Demberel, Jiro Nakayama

    Frontiers in Microbiology   15   2024.6

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)   Publisher:Frontiers Media SA  

    Mongolian people possess a unique dietary habit characterized by high consumption of meat and dairy products and fewer vegetables, resulting in the highest obesity rate in East Asia. Although obesity is a known cause of type 2 diabetes (T2D), the T2D rate is moderate in this population; this is known as the “Mongolian paradox.” Since the gut microbiota plays a key role in energy and metabolic homeostasis as an interface between food and body, we investigated gut microbial factors involved in the prevention of the co-occurrence of T2D with obesity in Mongolians. We compared the gut microbiome and metabolome of Mongolian adults with obesity with T2D (DO: n = 31) or without T2D (NDO: n = 35). Dysbiotic signatures were found in the gut microbiome of the DO group; lower levels of Faecalibacterium and Anaerostipes which are known as short-chain fatty acid (SCFA) producers and higher levels of Methanobrevibacter, Desulfovibrio, and Solobacterium which are known to be associated with certain diseases. On the other hand, the NDO group exhibited a higher level of fecal SCFA concentration, particularly acetate. This is consistent with the results of the whole shotgun metagenomic analysis, which revealed a higher relative abundance of SCFA biosynthesis-related genes encoded largely by Anaerostipes hadrus in the NDO group. Multiple logistic regression analysis including host demographic parameters indicated that acetate had the highest negative contribution to the onset of T2D. These findings suggest that SCFAs produced by the gut microbial community participate in preventing the development of T2D in obesity in Mongolians.

    DOI: 10.3389/fmicb.2024.1355396

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  • Crisis of the Asian gut: associations among diet, microbiota, and metabolic diseases Reviewed

    Phatthanaphong THERDTATHA, Akari SHINODA, Jiro NAKAYAMA

    Bioscience of Microbiota, Food and Health   41 ( 3 )   83 - 93   2022

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    Publishing type:Research paper (scientific journal)   Publisher:BMFH Press  

    DOI: 10.12938/bmfh.2021-085

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  • Comparative study of gut microbiota Mongolian and Asian people Reviewed

    Akari Shinoda, Demberel Shirchin, Dugersuren Jamiyan, Tsogtbaatar Lkhagvajav, Chantsaldulam Purevdorj, Sainbileg Sonomtseren, Battogtokh Chimiddorj, Bira Namdag, Phatthanaphong Therdtatha, Jiro Nakayama

    Mongolian Journal of Agricultural Sciences   33 ( 2 )   1 - 7   2021.9

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)   Publisher:Mongolian Journals Online  

    Mongolia has the unique dietary habit having a great deal of animal products especially among rural resident.To capture the status of Mongolian gut microbiome, we characterized bacterial community of 98 healthy Mongolian adults and compared with that of adults in five Asian countries, including Korea, China, Japan, Thailand and Indonesia. Principal component analysis (PCA) was performed based on genus composition of each sample. As a result, three microbiome-type cluster, the so-called “enterotype”, driven by the three taxonomic groups, Prevotella (P-type), Bacteroides and Bifidobacterium (BB-type), and Ruminococcaceae (R-type), were observed. Most of Mongolian subjects harbored P-type, which is known to strongly depend on carbohydrate-based diets. Further, the metagenomic analysis indicated that Catenibacterium and Lactobacillus were enriched in Mongolian subjects which may be concerned with intake of animal-based and dairy products-based diets, respectively. These results suggest that gut microbiome status of Mongolian people associates with the traditional unique dietary habit.

    DOI: 10.5564/mjas.v33i2.1744

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  • アジア人の食習慣と腸内細菌叢の変化と現代生活習慣病リスク向上の関連性について

    篠田あかり, 渡邉麻衣, THERDTATHA phatthanaphong, 中山二郎

    In実験医学増刊 Vol.39 個人差の理解へ向かう肥満症研究(梶村真吾, 小川佳宏, 矢作直也/編)   39   165 - 172   2021

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MISC

  • 腸内マイクロバイオームと糞便及び血清メタボロームの変容は慢性腎臓病の重症度と関連する Invited

    篠田あかり, 中山二郎

    Microbiome Science 2   239 - 240   2023

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    Authorship:Lead author  

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Presentations

  • モンゴル国の伝統発酵馬乳アイラグが腸内細菌叢に与える影響

    篠田あかり, ツォグトバートル・ルハグワジャブ, ドゥゲルスレン・ジャミヤン, デンベレル・シルチン, 中山二郎

    生物工学若手研究者の集い 夏のセミナー2026  2026.7.11 

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    Language:Japanese   Presentation type:Poster presentation  

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  • Toward an understanding of microbial circulation in the Mongolian nomadic ecosystem Invited

    Akari Shinoda

    iTHEMS biology seminar  2026.7.6 

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    Language:English   Presentation type:Public lecture, seminar, tutorial, course, or other speech  

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  • A Long History of Dairy – Gut Microbiota and Traditional Dairy Consumption in Mongolia Invited

    A SHINODA, A HÜBNER, J NAKAYAMA, C WARINNER

    11th Beneficial Microbes Conference  2025.11.3 

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    Presentation type:Oral presentation (invited, special)  

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  • The Impact of container modernization on airag, traditional Mongolian fermented mare's milk

    A. Shinoda

    7th Oxford Interdisciplinary Desert Conference  2025.3.20 

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    Presentation type:Oral presentation (general)  

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  • Comparison of gut microbiota between diabetic and non-diabetic obese Mongolian

    A. Shinoda, S. Demberel, D. Jamiyan, T. Lkhagvajav, J. Nakayama

    The 10th beneficial microbes conference  2023.11.28 

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    Presentation type:Poster presentation  

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  • How the difference of containers affects the Airag microbiome

    A. Shinoda, Y. Morinaga, R. Tsuchiya, B. Tserenpurev, P. Yadamjav, B. Badgar, J. Nakayama

    The 13th Asian Conference for Lactic Acid Bacteria  2023.8.17 

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  • Study on microbiota of Mongolian herdsmen intestine and fermented horse milk "Airag"

    A. Shinoda, T. Lkhagvajav, D. Shirchin, A. Nagashima, J. Nakayama

    The 13th Asian Conference for Lactic Acid Bacteria  2023.8.17 

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    Language:English   Presentation type:Oral presentation (general)  

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  • モンゴル国における2 型糖尿病肥満者と非2 型糖尿病肥満者の腸内細菌叢の比較

    篠田あかり, デンベレルシルチン, ジャムヤンドゴースレン, ラハクバジャウツォクトバートル, 中山二郎

    生物工学若手研究者の集い 夏のセミナー2023  2023.6.24 

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  • モンゴル国における2型糖尿病肥満者と非2型糖尿病肥満者の腸内細菌叢の比較

    篠田あかり

    「Kyushu University Asia Week 2022」 アジア・オセアニア賞  2022.11.7 

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  • Comparison of gut microbiota between diabetic and non-diabetic obese Mongolian

    A. Shinoda, S. Demberel, R. Mishima, D. Jamyan, T. Lkhagvajav, J. Nakayama

    The 11th Asian Conference for Lactic Acid Bacteria  2021.11.5 

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  • 腸内環境および免疫機能に及ぼすあまおう乳酸菌およびフコイダンの摂食効果

    篠田あかり, 朴俊夏, 中野勇人, 柴崎哲哉, 宮﨑義之, 中山二郎

    日本農芸化学会2021年度大会  2021.3.20 

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  • モンゴル人の腸内フローラと肥満および2 型糖尿病との関係

    篠田あかり, デンベレルシルチン, 三島梨子, ジャムヤンドゴースレン, ラハクバジャウツォクトバー, トル, 中山二郎

    日本乳酸菌学会2020 年度大会  2020.11.27 

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  • モンゴル人の腸内フローラと生活習慣病との関係

    篠田あかり, デンベレルシルチン, 三島梨子, 田中優, 堀野美里, ジャムヤンドゴースレン, ラハクバジ ャウツォクトバートル, 中山二郎

    日本農芸化学会 2020 年度大会  2020.3.27 

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  • Comparison of the gut microbiota of Mongolian with five Asian countries

    A. Shinoda, S. Demberel, R. Mishima, J. Nakayama

    JSBBA West 2nd Student Forum  2019.11.30 

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Awards

  • Best Presentation Award to Young Scientists

    2023.8   The 13th Asian Conference on Lactic Acid Bacteria   How the difference of containers affects the Airag microbiome

    A. Shinoda, Y. Morinaga, R. Tsuchiya, B. Tserenpurev, P. Yadamjav, B. Badgar, J. Nakayama.

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  • Best Presentation Award to Young Scientists

    2023.8   The 13th Asian Conference on Lactic Acid Bacteria   Study on microbiota of Mongolian herdsmen intestine and fermented horse milk "Airag"

    A. Shinoda, T. Lkhagvajav, D. Shirchin, A. Nagashima, J. Nakayama

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  • 優秀賞, 異分野プレゼン賞, 専門分野賞

    2023.6   生物工学若手研究者の集い 夏のセミナー2023   モンゴル国における2 型糖尿病肥満者と非2 型糖尿病肥満者の腸内細菌叢の比較

    篠田あかり, デンベレルシルチン, ジャムヤンドゴースレン, ラハクバジャウツォクトバートル,中山二郎

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  • 最優秀賞受賞

    2022.11   「Kyushu University Asia Week 2022」 アジア・オセアニア賞   モンゴル国における2型糖尿病肥満者と非2型糖尿病肥満者の腸内細菌叢の比較

    篠田あかり

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  • Best Presentation Award to Young Scientists

    2021.11   The 11th Asian Conference on Lactic Acid Bacteria   Comparison of gut microbiota between diabetic and non-diabetic obese Mongolian

    A. Shinoda, S. Demberel, R. Mishima, D. Jamyan, T. Lkhagvajav, J. Nakayama

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  • Best Presentation Award

    2021.9   JSBBA West 2nd Student Forum   Comparison of the gut microbiota of Mongolian with five Asian countries

    A. Shinoda, S. Demberel, R. Mishima, J. Nakayama

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Research Projects

  • 遊牧的牧畜と工業的畜産は発酵にどう違いを生むか―発酵馬乳の微生物群集と機能形成―

    2026.08 - 2028.03

    日本学術振興会 科学研究費助成事業 研究活動スタート支援 

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  • Establishing a Research Foundation toward Elucidating the Mechanisms of Microbial Community Assembly in Mongolian Fermented Dairy Products

    2026.06 - 2028.05

    公益財団法⼈公益推進協会  くら基⾦ 若⼿研究者奨励助成 

    Akari Shinoda, Dashyam Punsaldula

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    Authorship:Principal investigator 

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  • A Study on the Diversity, Functions, and Applicability of Lactic Acid Bacteria Isolated from Plant Fruits in Okayama Prefecture

    2026.06 - 2027.03

    公益財団法人 八雲環境科学振興財団  環境研究助 

    荒川健佑, 篠田あかり

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    Authorship:Coinvestigator(s) 

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  • Elucidating the Husbandry Environmental Factors that Govern the Microbial Functions of Airag, a Traditional Mongolian Fermented Mare's Milk

    2026.06 - 2027.03

    Academic Center for Computing and Media Studies, Kyoto University  2026年度スーパーコンピュータ共同研究制度 若手・女性研究者奨励枠 

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  • Establishing a Research Foundation toward Elucidating the Effects of Fermented Dairy Consumption on the Gut Microbiota in Mongolia

    2026.05 - 2027.03

    岡山大学 ダイバーシティ推進本部 男女共同参画室  令和8年度女性研究者研究費支援事業(若手型・スタートアップ支援) 

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    Authorship:Principal investigator 

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  • Antidiabetic effect of Mongolian gut microbiota

    Grant number:22KJ2447  2023.03 - 2024.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for JSPS Fellows

    篠田 あかり

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    Grant amount:\1700000 ( Direct expense: \1700000 )

    モンゴル国では高脂質・高動物性たんぱく質の食生活を中心とし、肥満者が多いにも関わらず、肥満がリスク因子である2型糖尿病患者が少ない。そこで健康と深く関与する腸内細菌叢に着目した。モンゴル国の2型糖尿病肥満者(n=31)と非2型糖尿病肥満者(n=35)の腸内細菌の16S rRNAシーケンシング解析により、2型糖尿病肥満者においては短鎖脂肪酸生産菌であるAnaerostipes hadrusの有意な減少や、糞便中の短鎖脂肪酸(総短鎖脂肪酸、酢酸)の減少が観察された。該当年度は機能遺伝子の違いを明らかにするため、各群9名ずつのショットガンメタゲノムシーケンシング解析を行った。その結果、2型糖尿病肥満者においては、糖の輸送や取り込みに関与するホスホトランスフェラーゼシステム関連遺伝子や短鎖脂肪酸代謝に関与する機能遺伝子量の減少がみられた。いずれの遺伝子も2型糖尿病肥満者におけるA. hadrus量の低下が本群における関連遺伝子の減少に関与していることが示された。最後に、A. hadrusや短鎖脂肪酸(総短鎖脂肪酸、酢酸)について、2型糖尿病の罹患に関連するオッズ比を年齢や地域などの交絡要因を補正して算出した。その結果、酢酸と総短鎖脂肪酸は有意に負に2型糖尿病の罹患と関係することが示された(95% 信頼区間, 酢酸:0.42 [0.23-0.79], 総短鎖脂肪酸: 0.65 [0.47-0.91])。以上メタゲノムシーケンシングおよび16S rRNAシーケンシング解析より、モンゴル国の肥満者の腸内においては、A. hadrusをはじめとする短鎖脂肪酸菌が産生する短鎖脂肪酸が2型糖尿病を抑制する因子であることが示唆された。

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  • モンゴル国における2型糖尿病肥満者と非2型糖尿病肥満者の腸内細菌叢の比較

    2022.04 - 2023.03

    九州大学 アジア・オセアニア研究教育機構  「Kyushu University Asia Week 2022」 アジア・オセアニア賞 

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  • モンゴル人の腸内フローラと健康と食の関係

    2022.01 - 2022.12

    ANRI  基礎科学スカラーシップ 

    篠田あかり

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  • モンゴル国における環境微生物と食の季節変化が人畜の腸内細菌叢に及ぼす影響

    2021.10 - 2022.03

    九州大学  次世代挑戦的プログラム 

    篠田あかり

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