論文 - 茶谷 悠平
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A mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism. 査読 国際誌
Yushin Ando, Akinao Kobo, Tatsuya Niwa, Ayako Yamakawa, Suzuna Konoma, Yuki Kobayashi, Osamu Nureki, Hideki Taguchi, Yuzuru Itoh, Yuhei Chadani
Nature communications 16 ( 1 ) 2323 - 2323 2025年3月
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STALL-seq: mRNA-display selection of bacterial and eukaryotic translational arrest sequences from large random-sequence libraries. 査読 国際誌
Tadashi Hamano, Yu Nagumo, Tomofumi Umehara, Kota Hirono, Kei Fujiwara, Hideki Taguchi, Yuhei Chadani, Nobuhide Doi
The Journal of biological chemistry 300 ( 12 ) 107978 - 107978 2024年11月
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Nonspecific N-terminal tetrapeptide insertions disrupt the translation arrest induced by ribosome-arresting peptide sequences. 査読 国際誌
Akinao Kobo, Hideki Taguchi, Yuhei Chadani
The Journal of biological chemistry 300 ( 6 ) 107360 - 107360 2024年6月
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The ABCF proteins in Escherichia coli individually cope with 'hard-to-translate' nascent peptide sequences. 査読 国際誌
Yuhei Chadani, Shun Yamanouchi, Eri Uemura, Kohei Yamasaki, Tatsuya Niwa, Toma Ikeda, Miku Kurihara, Wataru Iwasaki, Hideki Taguchi
Nucleic acids research 2024年4月
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Mechanistic dissection of premature translation termination induced by acidic residues-enriched nascent peptide 査読
Yuhei Chadani, Takashi Kanamori, Tatsuya Niwa, Kazuya Ichihara, Keiichi I. Nakayama, Akinobu Matsumoto, Hideki Taguchi
Cell Reports 42 ( 12 ) 113569 - 113569 2023年12月
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Shinobu Chiba, Keigo Fujiwara, Yuhei Chadani, Hideki Taguchi
The Journal of Biochemistry 173 ( 4 ) 227 - 236 2023年1月
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A method to enrich polypeptidyl-tRNAs to capture snapshots of translation in the cell. 査読 国際誌
Ayako Yamakawa, Tatsuya Niwa, Yuhei Chadani, Akinao Kobo, Hideki Taguchi
Nucleic acids research 2023年1月
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Nascent peptide-induced translation discontinuation in eukaryotes impacts biased amino acid usage in proteomes. 査読 国際誌
Yosuke Ito, Yuhei Chadani, Tatsuya Niwa, Ayako Yamakawa, Kodai Machida, Hiroaki Imataka, Hideki Taguchi
Nature communications 13 ( 1 ) 7451 - 7451 2022年12月
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Prophage excision switches the primary ribosome rescue pathway and rescue-associated gene regulations in Escherichia coli. 査読 国際誌
Haruka Onodera, Tatsuya Niwa, Hideki Taguchi, Yuhei Chadani
Molecular microbiology 119 ( 1 ) 44 - 58 2022年11月
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Shotgun Proteomics Revealed Preferential Degradation of Misfolded In Vivo Obligate GroE Substrates by Lon Protease in Escherichia coli. 査読 国際誌
Tatsuya Niwa, Yuhei Chadani, Hideki Taguchi
Molecules (Basel, Switzerland) 27 ( 12 ) 2022年6月
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Nascent polypeptide within the exit tunnel stabilizes the ribosome to counteract risky translation. 査読 国際誌
Yuhei Chadani, Nobuyuki Sugata, Tatsuya Niwa, Yosuke Ito, Shintaro Iwasaki, Hideki Taguchi
The EMBO journal 40 ( 23 ) e108299 2021年10月
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Transcription-translation of the Escherichia coli genome within artificial cells. 査読 国際誌
Tatsuki Deyama, Yukino Matsui, Yuhei Chadani, Yasuhiko Sekine, Nobuhide Doi, Kei Fujiwara
Chemical communications (Cambridge, England) 57 ( 80 ) 10367 - 10370 2021年10月
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Escherichia coli small heat shock protein IbpA is an aggregation-sensor that self-regulates its own expression at posttranscriptional levels. 査読 国際誌
Tsukumi Miwa, Yuhei Chadani, Hideki Taguchi
Molecular microbiology 115 ( 1 ) 142 - 156 2020年10月
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Intrinsic Ribosome Destabilization Underlies Translation and Provides an Organism with a Strategy of Environmental Sensing. 査読 国際誌
Yuhei Chadani, Tatsuya Niwa, Takashi Izumi, Nobuyuki Sugata, Asuteka Nagao, Tsutomu Suzuki, Shinobu Chiba, Koreaki Ito, Hideki Taguchi
Molecular cell 68 ( 3 ) 528 - 539 2017年11月
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Integrated in vivo and in vitro nascent chain profiling reveals widespread translational pausing. 査読 国際誌
Yuhei Chadani, Tatsuya Niwa, Shinobu Chiba, Hideki Taguchi, Koreaki Ito
Proceedings of the National Academy of Sciences of the United States of America 113 ( 7 ) E829-38 2016年2月
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大腸菌の持つ二段構えのリボソーム解放機構
阿保達彦, 茶谷悠平
生化学 87 ( 6 ) 736 - 40 2015年12月
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ArfA recognizes the lack of mRNA in the mRNA channel after RF2 binding for ribosome rescue. 査読 国際誌
Daisuke Kurita, Yuhei Chadani, Akira Muto, Tatsuhiko Abo, Hyouta Himeno
Nucleic acids research 42 ( 21 ) 13339 - 52 2014年12月
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The fail-safe system to rescue the stalled ribosomes in Escherichia coli. 査読 国際誌
Tatsuhiko Abo, Yuhei Chadani
Frontiers in microbiology 5 156 - 156 2014年
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ArfA recruits release factor 2 to rescue stalled ribosomes by peptidyl-tRNA hydrolysis in Escherichia coli. 査読 国際誌
Yuhei Chadani, Koreaki Ito, Kazuhiro Kutsukake, Tatsuhiko Abo
Molecular microbiology 86 ( 1 ) 37 - 50 2012年10月
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Escherichia coli YaeJ protein mediates a novel ribosome-rescue pathway distinct from SsrA- and ArfA-mediated pathways. 査読 国際誌
Yuhei Chadani, Katsuhiko Ono, Kazuhiro Kutsukake, Tatsuhiko Abo
Molecular microbiology 80 ( 3 ) 772 - 85 2011年5月
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Nascentome analysis uncovers futile protein synthesis in Escherichia coli. 査読 国際誌
Koreaki Ito, Yuhei Chadani, Kenta Nakamori, Shinobu Chiba, Yoshinori Akiyama, Tatsuhiko Abo
PloS one 6 ( 12 ) e28413 2011年
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trans-translation-mediated tight regulation of the expression of the alternative ribosome-rescue factor ArfA in Escherichia coli. 査読
Yuhei Chadani, Emi Matsumoto, Hiroaki Aso, Takeo Wada, Kazuhiro Kutsukake, Shizuyo Sutou, Tatsuhiko Abo
Genes & genetic systems 86 ( 3 ) 151 - 63 2011年
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Ribosome rescue by Escherichia coli ArfA (YhdL) in the absence of trans-translation system. 査読 国際誌
Yuhei Chadani, Katsuhiko Ono, Shin-Ichiro Ozawa, Yuichiro Takahashi, Kazuyuki Takai, Hideaki Nanamiya, Yuzuru Tozawa, Kazuhiro Kutsukake, Tatsuhiko Abo
Molecular microbiology 78 ( 4 ) 796 - 808 2010年11月