2024/05/24 更新

写真a

ナイトウ ヒロミチ
内藤 宏道
NAITOU Hiromichi
所属
医歯薬学域 准教授
職名
准教授
外部リンク

学位

  • 博士(医学) ( 2013年6月   岡山大学 )

  • 医学博士(岡山大学) ( 2013年6月   岡山大学大学院 医歯薬学総合研究科 )

研究キーワード

  • 院外心停止

  • 気道管理

  • 心肺蘇生

  • 病院前診療

  • 心停止後症候群

研究分野

  • ライフサイエンス / 救急医学

学歴

  • 岡山大学医学部医学科    

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  • University of Pittsburgh School of Medicine   Department of Emergency Medicine  

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    備考: Visiting Researcher

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  • 岡山大学大学院    

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経歴

所属学協会

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委員歴

  • 日本集中治療医学会   災害時の集中治療検討委員会  

    2023年 - 現在   

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  • 日本救急医学会   シニア救急医のキャリア支援を考えるワーキンググループ  

    2022年 - 現在   

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  • 日本救急医学会   脳死・臓器組織移植に関する委員会  

    2021年1月 - 2022年12月   

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    団体区分:学協会

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  • 日本救急医学会   評議員  

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  • 日本集中治療医学会   評議員  

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  • 日本中毒学会 評議員  

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  • 日本中毒学会 評議員選出委員会  

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  • 日本外傷学会 評議員  

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論文

  • Effect of Stomach Inflation during Cardiopulmonary Resuscitation on Return of Spontaneous Circulation in Out-of-Hospital Cardiac Arrest Patients: A Retrospective Observational Study. 国際誌

    Hiromichi Naito, Hiroaki Hanafusa, Takashi Hongo, Tetsuya Yumoto, Takashi Yorifuji, Alexandra Weissman, Jon C Rittenberger, Francis X Guyette, Mamoru Fujishima, Hiroki Maeyama, Astunori Nakao

    Resuscitation   109994 - 109994   2023年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Gastric inflation caused by excessive ventilation is a common complication of cardiopulmonary resuscitation. Gastric inflation may further compromise ventilation via increases in intrathoracic pressure, leading to decreased venous return and cardiac output, which may impair out-of-hospital cardiac arrest (OHCA) outcomes. The purpose of this study was to measure the gastric volume of OHCA patients using computed tomography (CT) scan images and evaluate the effect of gastric inflation on return of spontaneous circulation (ROSC). METHODS: In this single-center, retrospective, observational study, CT scan was conducted after ROSC or immediately after death. Total gastric volume was measured. Primary outcome was ROSC. Achievement of ROSC was compared in the gastric distention group and the no gastric distention group; gastric distension was defined as total gastric volume in the ≥75th percentile. Additionally, factors associated with gastric distention were examined. RESULTS: A total of 446 cases were enrolled in the study; 120 cases (27%) achieved ROSC. The median gastric volume was 400 ml for all OHCA subjects; 1068 ml in gastric distention group vs. 287 ml in no gastric distention group. There was no difference in ROSC between the groups (27/112 [24.1%] vs. 93/334 [27.8%], p=0.440). Gastric distention did not have a significant impact, even after adjustments (adjusted odds ratio 0.73, 95% confidence interval [0.42 - 1.29]). Increased gastric volume was associated with longer emergency medical service activity time. CONCLUSIONS: We observed a median gastric volume of 400 ml in patients after OHCA resuscitation. In our setting, gastric distention did not prevent ROSC.

    DOI: 10.1016/j.resuscitation.2023.109994

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  • Prevalence, reasons, and timing of decisions to withhold/withdraw life-sustaining therapy for out-of-hospital cardiac arrest patients with extracorporeal cardiopulmonary resuscitation 査読 国際誌

    Hiromichi Naito, Masaaki Sakuraya, Takashi Hongo, Hiroaki Takada, Tetsuya Yumoto, Takashi Yorifuji, Toru Hifumi, Akihiko Inoue, Tetsuya Sakamoto, Yasuhiro Kuroda, Atsunori Nakao

    Critical Care   27 ( 1 )   2023年6月

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)   出版者・発行元:Springer Science and Business Media LLC  

    Abstract

    Background

    Extracorporeal cardiopulmonary resuscitation (ECPR) is rapidly becoming a common treatment strategy for patients with refractory cardiac arrest. Despite its benefits, ECPR raises a variety of ethical concerns when the treatment is discontinued. There is little information about the decision to withhold/withdraw life-sustaining therapy (WLST) for out-of-hospital cardiac arrest (OHCA) patients after ECPR.

    Methods

    We conducted a secondary analysis of data from the SAVE-J II study, a retrospective, multicenter study of ECPR in Japan. Adult patients who underwent ECPR for OHCA with medical causes were included. The prevalence, reasons, and timing of WLST decisions were recorded. Outcomes of patients with or without WLST decisions were compared. Further, factors associated with WLST decisions were examined.

    Results

    We included 1660 patients in the analysis; 510 (30.7%) had WLST decisions. The number of WLST decisions was the highest on the first day and WSLT decisions were made a median of two days after ICU admission. Reasons for WLST were perceived unfavorable neurological prognosis (300/510 [58.8%]), perceived unfavorable cardiac/pulmonary prognosis (105/510 [20.5%]), inability to maintain extracorporeal cardiopulmonary support (71/510 [13.9%]), complications (10/510 [1.9%]), exacerbation of comorbidity before cardiac arrest (7/510 [1.3%]), and others. Patients with WLST had lower 30-day survival (WLST vs. no-WLST: 36/506 [7.1%] vs. 386/1140 [33.8%], p < 0.001). Primary cerebral disorders as cause of cardiac arrest and higher severity of illness at intensive care unit admission were associated with WLST decisions.

    Conclusion

    For approximately one-third of ECPR/OHCA patients, WLST was decided during admission, mainly because of perceived unfavorable neurological prognoses. Decisions and neurological assessments for ECPR/OHCA patients need further analysis.

    DOI: 10.1186/s13054-023-04534-2

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    その他リンク: https://link.springer.com/article/10.1186/s13054-023-04534-2/fulltext.html

  • Mid-term (30- to 90-day) neurological changes in out-of-hospital cardiac arrest patients: A nationwide retrospective study (the JAAM-OHCA registry). 国際誌

    Hiromichi Naito, Tsuyoshi Nojima, Takashi Yorifuji, Noritomo Fujisaki, Atsunori Nakao

    The American journal of emergency medicine   58   27 - 32   2022年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    OBJECTIVE: Few studies have focused on mid/long-term neurological changes in out-of- hospital cardiac arrest (OHCA) survivors. Some studies suggest that there is still a slow, small, progressive improvement in cognitive function and quality of life for this population, even in the mid/long term. However, clinical data focused on mid/long-term outcomes for OHCA patients are still lacking. This study aimed to assess mid-term neurological changes in OHCA patients. We summarized patients' improved or worsened neurological changes between 30 and 90 days. Then we identified the relationship between clinical variables and 30- to 90-day neurological improvement. METHODS: A retrospective review of data (Jun 2014 - Dec 2017) from a Japanese nationwide OHCA registry was conducted. Inclusion criteria were OHCA patients ≥18 years old. Exclusion criteria were death within 30 days and missing Cerebral Performance Category (CPC) score at 30 and 90 days. We described the distributions of 30-day and 90-day CPC scores as well as the number and portion of patients whose CPC scores improved and worsened between 30 and 90 days. Additionally, factors affecting improved neurological changes over the time period were examined using multivariable logistic regression. RESULTS: Of the registry's 34,745 patients, 1868 were analyzed. Favorable neurological outcomes (CPC scores of 1 and 2) were seen in 1020/1868 patients at 90 days. CPC scores at 90 days were: CPC 1: 866 (46%), CPC 2: 154 (8.2%), CPC 3: 224 (12%), and CPC 4: 392 (20%), respectively. A total of 232 patients (CPC 5: 12%) died between 30 and 90 days. In 133 patients (7%), 90-day CPC scores improved compared to their 30-day scores. In 260 patients (14%), 90-day CPC scores worsened compared with their 30-day scores. Application of target temperature management was an independent factor for 30- to 90-day neurological improvement (adjusted odds ratio: 1.69, 95% confidence interval: 1.07-2.68). CONCLUSIONS: In our nationwide registry, 7% of resuscitated patients had improved neurological changes in the 30- to 90-day period; most of the improvements were CPC scores improving from 2 to 1. Target temperature management was an independent factor associated with CPC improvement over the 30- to 90-day period.

    DOI: 10.1016/j.ajem.2022.05.017

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  • Association between emergency medical service transport time and survival in patients with traumatic cardiac arrest: a Nationwide retrospective observational study 査読 国際誌

    Hiromichi Naito, Tetsuya Yumoto, Takashi Yorifuji, Tsuyoshi Nojima, Hirotsugu Yamamoto, Taihei Yamada, Kohei Tsukahara, Mototaka Inaba, Takeshi Nishimura, Takenori Uehara, Atsunori Nakao

    BMC Emergency Medicine   21 ( 1 )   104 - 104   2021年12月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Springer Science and Business Media LLC  

    <title>Abstract</title><sec>
    <title>Background</title>
    Patients with traumatic cardiac arrest (TCA) are known to have poor prognoses. In 2003, the joint committee of the National Association of EMS Physicians and the American College of Surgeons Committee on Trauma proposed stopping unsuccessful cardiopulmonary resuscitation (CPR) sustained for &gt; 15 min after TCA. However, in 2013, a specific time-limit for terminating resuscitation was dropped, due to the lack of conclusive studies or data. We aimed to define the association between emergency medical services transport time and survival to demonstrate the survival curve of TCA.


    </sec><sec>
    <title>Methods</title>
    A retrospective review of the Japan Trauma Data Bank. Inclusion criteria were age ≥ 16, at least one trauma with Abbreviated Injury Scale score (AIS) ≥ 3, and CPR performed in a prehospital setting. Exclusion criteria were burn injury, AIS score of 6 in any region, and missing data. Estimated survival rate and risk ratio for survival were analyzed according to transport time for all patients. Analysis was also performed separately on patients with sustained TCA at arrival.


    </sec><sec>
    <title>Results</title>
    Of 292,027 patients in the database, 5336 were included in the study with 4141 sustained TCA. Their median age was 53 years (interquartile range (IQR) 36–70), and 67.2% were male. Their median Injury Severity Score was 29 (IQR 22–41), and median transport time was 11 min (IQR 6–17). Overall survival after TCA was 4.5%; however, survival of patients with sustained TCA at arrival was only 1.2%. The estimated survival rate and risk ratio for sustained TCA rapidly decreased after 15 min of transport time, with estimated survival falling below 1%.


    </sec><sec>
    <title>Conclusion</title>
    The chances of survival for sustained TCA declined rapidly while the patient is transported with CPR support. Time should be one reasonable factor for considering termination of resuscitation in patients with sustained TCA, although clinical signs of life, and type and severity of trauma should be taken into account clinically.


    </sec>

    DOI: 10.1186/s12873-021-00499-z

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    その他リンク: https://link.springer.com/article/10.1186/s12873-021-00499-z/fulltext.html

  • Prognostication after cardiac arrest: Results of an international, multi-professional survey 査読

    Alexis Steinberg, Clifton W. Callaway, Robert M. Arnold, Tobias Cronberg, Hiromichi Naito, Koral Dadon, Minjung Kathy Chae, Jonathan Elmer

    Resuscitation   138   190 - 197   2019年5月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier BV  

    DOI: 10.1016/j.resuscitation.2019.03.016

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  • Intracranial pressure increases during rewarming period after mild therapeutic hypothermia in postcardiac arrest patients. 査読

    Naito H, Isotani E, Callaway CW, Hagioka S, Morimoto N.

    Ther Hypothermia Temp Manag .   6 ( 4 )   189 - 193   2016年12月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1089/ther.2016.0009

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    その他リンク: https://www.liebertpub.com/doi/pdf/10.1089/ther.2016.0009

  • Video laryngoscopic techniques associated with intubation success in a helicopter emergency medical service system 査読

    Hiromichi Naito*,Francis X. Guyette,Christian Martin-Gill,Clifton W. Callaway

    Prehospital Emergency Care   20 ( 3 )   333 - 342   2016年5月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.3109/10903127.2015.1111480

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  • Impact of sex of bystanders who perform cardiopulmonary resuscitation on return of spontaneous circulation in out-of-hospital cardiac arrest patients: A retrospective, observational study. 国際誌

    Shunsuke Nakamura, Tsuyoshi Nojima, Takafumi Obara, Takashi Hongo, Tetsuya Yumoto, Takashi Yorifuji, Atsunori Nakao, Hiromichi Naito

    Resuscitation plus   18   100659 - 100659   2024年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: The impact of the sex of bystanders who initiate cardiopulmonary resuscitation (CPR) on out-of-hospital cardiac arrest (OHCA) patients has not been fully elucidated. This study aims to investigate the association between the sex of bystanders who perform CPR and the clinical outcomes of OHCA patients in real-world clinical settings. METHODS: We conducted a retrospective, observational study using data from the Okayama City Fire Department in Japan. Patients were categorized based on bystanders' sex. Our primary outcomes were return of spontaneous circulation (ROSC). Our secondary outcome was 30-day survival and 30-day favorable neurological outcome, defined as Cerebral Performance Category score of 1 or 2. Multivariable logistic regression analysis was used to examine the association between these groups and outcomes. RESULTS: The study included 3,209 patients with a comparable distribution of male (1,540 patients: 48.0%) and female bystanders (1,669 patients: 52.0%) between the groups. Overall, 221 (6.9%) ROSC at hospital arrival, 226 (7.0%) patients had 30-day survival, and 121 (3.8%) patients had 30-day favorable neurological outcomes. Bystander sex (female as reference) did not contribute to ROSC at hospital arrival (adjusted OR [aOR] 1.11, 95% CI: 0.76-1.61), 30-day survival (aOR 1.23, 95% CI: 0.83-1.82), or 30-day favorable neurological outcomes (aOR 0.66, 95% CI: 0.34-1.27). Basic life support education experience was a bystander factor positively associated with ROSC. Patient factors positively associated with ROSC were initial shockable rhythm and witness of cardiac arrest. CONCLUSION: There were no differences in ROSC, 30-day survival, or 30-day neurological outcomes in OHCA patients based on bystander sex.

    DOI: 10.1016/j.resplu.2024.100659

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  • Organ donation after extracorporeal cardiopulmonary resuscitation: a nationwide retrospective cohort study. 国際誌

    Tetsuya Yumoto, Kohei Tsukahara, Takafumi Obara, Takashi Hongo, Tsuyoshi Nojima, Hiromichi Naito, Atsunori Nakao

    Critical care (London, England)   28 ( 1 )   160 - 160   2024年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Limited data are available on organ donation practices and recipient outcomes, particularly when comparing donors who experienced cardiac arrest and received extracorporeal cardiopulmonary resuscitation (ECPR) followed by veno-arterial extracorporeal membrane oxygenation (ECMO) decannulation, versus those who experienced cardiac arrest without receiving ECPR. This study aims to explore organ donation practices and outcomes post-ECPR to enhance our understanding of the donation potential after cardiac arrest. METHODS: We conducted a nationwide retrospective cohort study using data from the Japan Organ Transplant Network database, covering all deceased organ donors between July 17, 2010, and August 31, 2022. We included donors who experienced at least one episode of cardiac arrest. During the study period, patients undergoing ECMO treatment were not eligible for a legal diagnosis of brain death. We compared the timeframes associated with each donor's management and the long-term graft outcomes of recipients between ECPR and non-ECPR groups. RESULTS: Among 370 brain death donors with an episode of cardiac arrest, 26 (7.0%) received ECPR and 344 (93.0%) did not; the majority were due to out-of-hospital cardiac arrests. The median duration of veno-arterial ECMO support after ECPR was 3 days. Patients in the ECPR group had significantly longer intervals from admission to organ procurement compared to those not receiving ECPR (13 vs. 9 days, P = 0.005). Lung graft survival rates were significantly lower in the ECPR group (log-rank test P = 0.009), with no significant differences in other organ graft survival rates. Of 160 circulatory death donors with an episode of cardiac arrest, 27 (16.9%) received ECPR and 133 (83.1%) did not. Time intervals from admission to organ procurement following circulatory death and graft survival showed no significant differences between ECPR and non-ECPR groups. The number of organs donated was similar between the ECPR and non-ECPR groups, regardless of brain or circulatory death. CONCLUSIONS: This nationwide study reveals that lung graft survival was lower in recipients from ECPR-treated donors, highlighting the need for targeted research and protocol adjustments in post-ECPR organ donation.

    DOI: 10.1186/s13054-024-04949-5

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  • Long-term, patient-centered, frailty-based outcomes of older critical illness survivors from the emergency department: a post hoc analysis of the LIFE Study. 国際誌

    Takashi Hongo, Tetsuya Yumoto, Mototaka Inaba, Shunsuke Taito, Takashi Yorifuji, Atsunori Nakao, Hiromichi Naito

    BMC geriatrics   24 ( 1 )   257 - 257   2024年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Evidence indicates frailty before intensive care unit (ICU) admission leads to poor outcomes. However, it is unclear whether quality of life (QOL) and activities of daily living (ADL) for survivors of critical illness admitted to the ICU via the emergency department remain consistent or deteriorate in the long-term compared to baseline. This study aimed to evaluate long-term QOL/ADL outcomes in these patients, categorized by the presence or absence of frailty according to Clinical Frailty Scale (CFS) score, as well as explore factors that influence these outcomes. METHODS: This was a post-hoc analysis of a prospective, multicenter, observational study conducted across Japan. It included survivors aged 65 years or older who were admitted to the ICU through the emergency department. Based on CFS scores, participants were categorized into either the not frail group or the frail group, using a threshold CFS score of < 4. Our primary outcome was patient-centered outcomes (QOL/ADL) measured by the five-level EuroQol five-dimensional questionnaire (EQ-5D-5L) and the Barthel Index six months post-ICU admission, comparing results from baseline. Secondary outcomes included exploration of factors associated with QOL/ADL six months post-ICU admission using multiple linear regression analyses. RESULTS: Of 514 candidates, 390 participants responded to the EQ-5D-5L questionnaire, while 237 responded to the Barthel Index. At six months post-admission, mean EQ-5D-5L values declined in both the not frail and frail groups (0.80 to 0.73, p = 0.003 and 0.58 to 0.50, p = 0.002, respectively); Barthel Index scores also declined in both groups (98 to 83, p < 0.001 and 79 to 61, p < 0.001, respectively). Multiple linear regression analysis revealed that baseline frailty (β coefficient, -0.15; 95% CI, - 0.23 to - 0.07; p < 0.001) and pre-admission EQ-5D-5L scores (β coefficient, 0.14; 95% CI, 0.02 to 0.26; p = 0.016) affected EQ-5D-5L scores at six months. Similarly, baseline frailty (β coefficient, -12.3; 95% CI, - 23.9 to - 0.80; p = 0.036) and Barthel Index scores (β coefficient, 0.54; 95% CI, 0.30 to 0.79; p < 0.001) influenced the Barthel Index score at six months. CONCLUSIONS: Regardless of frailty, older ICU survivors from the emergency department were more likely to experience reduced QOL and ADL six months after ICU admission compared to baseline.

    DOI: 10.1186/s12877-024-04881-x

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  • Changes in temporal muscle dimensions and their clinical impact in out-of-hospital cardiac arrest survivors

    Takashi Hongo, Hiromichi Naito, Keibun Liu, Yuya Murakami, Satoshi Nozaki, Hiroki Maeyama, Ayaka Matsuoka, Hisashi Dote, Kazumasa Inaba, Satoshi Miike, Shigeki Fujitani, Tomohiro Hiraoka, Takafumi Obara, Tsuyoshi Nojima, Atsunori Nakao, Tetsuya Yumoto

    Resuscitation Plus   17   100527 - 100527   2024年3月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier BV  

    DOI: 10.1016/j.resplu.2023.100527

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  • 法的脳死判定時にCPAPモードを用いた無呼吸テストを実施した小児2例

    平岡 知浩, 小原 隆史, 塚原 紘平, 難波 宏太, 岡田 真澄, 平山 隆浩, 湯本 哲也, 内藤 宏道, 中尾 篤典

    日本小児科学会雑誌   128 ( 2 )   361 - 361   2024年2月

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    記述言語:日本語   出版者・発行元:(公社)日本小児科学会  

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  • Successful Cardiac, Lung, and Kidney Transplantation from a Methanol-poisoned Donor.

    Takashi Hongo, Tetsuya Yumoto, Yoshinori Kosaki, Tomohiro Hiraoka, Kohei Tsukahara, Tsuyoshi Nojima, Takafumi Obara, Kohei Ageta, Yukie Yamasaki, Kaori Taniguchi, Masanobu Miura, Satoru Miyaishi, Hiromichi Naito, Atsunori Nakao

    JMA journal   7 ( 1 )   133 - 135   2024年1月

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    記述言語:英語  

    Massive methanol exposure can lead to severe and detrimental effects that can result in death or brain death. As organs from patients with brain death after methanol ingestion are less likely to be recovered, these patients have been considered marginal donors. We present a case of successful multiple organ transplantation (heart, lungs, and kidneys) from a methanol-poisoned patient. Our experience illustrates that donor death from methanol intoxication does not preclude organ transplantation.

    DOI: 10.31662/jmaj.2023-0081

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  • Hydrogen in Transplantation: Potential Applications and Therapeutic Implications. 国際誌

    Takafumi Obara, Hiromichi Naito, Tsuyoshi Nojima, Takahiro Hirayama, Takashi Hongo, Kohei Ageta, Toshiyuki Aokage, Masaki Hisamura, Tetsuya Yumoto, Atsunori Nakao

    Biomedicines   12 ( 1 )   2024年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Hydrogen gas, renowned for its antioxidant properties, has emerged as a novel therapeutic agent with applications across various medical domains, positioning it as a potential adjunct therapy in transplantation. Beyond its antioxidative properties, hydrogen also exerts anti-inflammatory effects by modulating pro-inflammatory cytokines and signaling pathways. Furthermore, hydrogen's capacity to activate cytoprotective pathways bolsters cellular resilience against stressors. In recent decades, significant advancements have been made in the critical medical procedure of transplantation. However, persistent challenges such as ischemia-reperfusion injury (IRI) and graft rejection continue to hinder transplant success rates. This comprehensive review explores the potential applications and therapeutic implications of hydrogen in transplantation, shedding light on its role in mitigating IRI, improving graft survival, and modulating immune responses. Through a meticulous analysis encompassing both preclinical and clinical studies, we aim to provide valuable insights into the promising utility of hydrogen as a complementary therapy in transplantation.

    DOI: 10.3390/biomedicines12010118

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  • Association of initial lactate levels and red blood cell transfusion strategy with outcomes after severe trauma: a post hoc analysis of the RESTRIC trial. 国際誌

    Yoshinori Kosaki, Takashi Hongo, Mineji Hayakawa, Daisuke Kudo, Shigeki Kushimoto, Takashi Tagami, Hiromichi Naito, Atsunori Nakao, Tetsuya Yumoto

    World journal of emergency surgery : WJES   19 ( 1 )   1 - 1   2024年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: The appropriateness of a restrictive transfusion strategy for those with active bleeding after traumatic injury remains uncertain. Given the association between tissue hypoxia and lactate levels, we hypothesized that the optimal transfusion strategy may differ based on lactate levels. This post hoc analysis of the RESTRIC trial sought to investigate the association between transfusion strategies and patient outcomes based on initial lactate levels. METHODS: We performed a post hoc analysis of the RESTRIC trial, a cluster-randomized, crossover, non-inferiority multicenter trials, comparing a restrictive and liberal red blood cell transfusion strategy for adult trauma patients at risk of major bleeding. This was conducted during the initial phase of trauma resuscitation; from emergency department arrival up to 7 days after hospital admission or intensive care unit (ICU) discharge. Patients were grouped by lactate levels at emergency department arrival: low (< 2.5 mmol/L), middle (≥ 2.5 and < 4.0 mmol/L), and high (≥ 4.0 mmol/L). We compared 28 days mortality and ICU-free and ventilator-free days using multiple linear regression among groups. RESULTS: Of the 422 RESTRIC trial participants, 396 were analyzed, with low (n = 131), middle (n = 113), and high (n = 152) lactate. Across all lactate groups, 28 days mortality was similar between strategies. However, in the low lactate group, the restrictive approach correlated with more ICU-free (β coefficient 3.16; 95% CI 0.45 to 5.86) and ventilator-free days (β coefficient 2.72; 95% CI 0.18 to 5.26) compared to the liberal strategy. These findings persisted even after excluding patients with severe traumatic brain injury. CONCLUSIONS: Our results suggest that restrictive transfusion strategy might not have a significant impact on 28-day survival rates, regardless of lactate levels. However, the liberal transfusion strategy may lead to shorter ICU- and ventilator-free days for patients with low initial blood lactate levels.

    DOI: 10.1186/s13017-023-00530-7

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  • Reply to: Stomach inflation during cardiopulmonary resuscitation in out-of-hospital cardiac arrest patients: where did the air go? 国際誌

    Hiromichi Naito, Takashi Hongo, Tetsuya Yumoto, Hiroki Maeyama, Astunori Nakao

    Resuscitation   110099 - 110099   2023年12月

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  • Treatment patterns and clinician stress related to care of out-of-hospital cardiac arrest patients with a do not attempt resuscitation order. 国際誌

    Ryo Tanabe, Takashi Hongo, Takafumi Obara, Tsuyoshi Nojima, Atsunori Nakao, Jonathan Elmer, Hiromichi Naito, Tetsuya Yumoto

    Resuscitation plus   16   100507 - 100507   2023年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    OBJECTIVE: This research investigated treatment patterns for out-of-hospital cardiac arrest patients with Do Not Attempt Resuscitation orders in Japanese emergency departments and the associated clinician stress. METHODS: A cross-sectional survey was conducted at 9 hospitals in Okayama, Japan, targeting emergency department nurses and physicians. The questionnaire inquired about the last treated out-of-hospital cardiac arrest patient with a Do Not Attempt Resuscitation. We assessed emotional stress on a 0-10 scale and moral distress on a 1-5 scale among clinicians. RESULTS: Of 208 participants, 107 (51%) had treated an out-of-hospital cardiac arrest patient with a Do Not Attempt Resuscitation order in the past 6 months. Of these, 65 (61%) clinicians used a "slow code" due to perceived futility in resuscitation (42/65 [65%]), unwillingness to terminate resuscitation upon arrival (38/65 [59%]), and absence of family at the time of patient's arrival (35/65 [54%]). Female clinicians had higher emotional stress (5 vs. 3; P = 0.007) and moral distress (3 vs. 2; P = 0.002) than males. Nurses faced more moral distress than physicians (3 vs. 2; P < 0.001). Adjusted logistic regression revealed that having performed a "slow code" (adjusted odds ratio, 5.09 [95% CI, 1.68-17.87]) and having greater ethical concerns about "slow code" (adjusted odds ratio, 0.35 [95% CI, 0.19-0.58]) were associated with high stress levels. CONCLUSIONS: The prevalent use of "slow code" for out-of-hospital cardiac arrest patients with Do Not Attempt Resuscitation orders underscores the challenges in managing these patients in clinical practice.

    DOI: 10.1016/j.resplu.2023.100507

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  • 蘇生を希望しない院外心停止の診療に関する救急外来での実態調査 多機関共同横断研究

    田邉 綾, 湯本 哲也, 本郷 貴識, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   34 ( 12 )   720 - 720   2023年12月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 暑熱環境下における気温上昇と心血管救急搬送リスクとの関連 時間依存の予防対策

    藤本 竜平, 鈴木 越治, 鹿嶋 小緒里, 内藤 宏道, 中村 一文, 中尾 篤典, 岡 岳文, 伊藤 浩, 頼藤 貴志

    日本救急医学会雑誌   34 ( 12 )   739 - 739   2023年12月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • アセトアミノフェン中毒に対する一酸化炭素放出物質(CORM-401)の新規治療法としての可能性

    青景 聡之, Meng Ying, 小原 隆史, 湯本 哲也, 平山 隆浩, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   34 ( 12 )   717 - 717   2023年12月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • Radiation in an emergency situation: attempting to respect the patient's beliefs as reported by a minor. 国際誌

    Tetsuya Yumoto, Takashi Hongo, Yasuhiro Koide, Takafumi Obara, Kohei Tsukahara, Hiromichi Naito, Atsunori Nakao

    BMC medical ethics   24 ( 1 )   80 - 80   2023年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Each individual's unique health-related beliefs can greatly impact the patient-clinician relationship. When there is a conflict between the patient's preferences and recommended medical care, it can create a serious ethical dilemma, especially in an emergency setting, and dramatically alter this important relationship. CASE PRESENTATION: A 56-year-old man, who remained comatose after out-of-hospital cardiac arrest, was rushed to our hospital. The patient was scheduled for emergency coronary angiography when his adolescent daughter reported that she and her father held sincere beliefs against radiation exposure. We were concerned that she did not fully understand the potential consequences if her father did not receive the recommended treatment. A physician provided her with in depth information regarding the risks and benefits of the treatment. While we did not want to disregard her statement, we opted to save the patient's life due to concerns about the validity of her report. CONCLUSIONS: Variations in beliefs regarding medical care force clinicians to incorporate patient beliefs into medical practice. However, an emergency may require a completely different approach. When faced with a patient in a life-threatening condition and unconscious, we should take action to prioritize saving their life, unless we are highly certain about the validity of their advance directives.

    DOI: 10.1186/s12910-023-00962-5

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  • Collapse-related traumatic intracranial hemorrhage following out-of-hospital cardiac arrest: A multicenter retrospective cohort study. 国際誌

    Fumiya Inoue, Takashi Hongo, Toshihisa Ichiba, Takayuki Otani, Hiroshi Naito, Yoshinori Kosaki, Yuya Murakami, Atsuyoshi Iida, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao

    Resuscitation plus   15   100418 - 100418   2023年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Sudden loss of consciousness as a result of cardiac arrest can cause severe traumatic head injury. Collapse-related traumatic intracranial hemorrhage (CRTIH) following out-of-hospital cardiac arrest (OHCA) may be linked to poor neurological outcomes; however, there is a paucity of data on this entity. This study aimed to investigate the frequency, characteristics, and outcomes of CRTIH following OHCA. METHODS: Adult patients treated post-OHCA at 5 intensive care units who had head computed tomography (CT) scans were included in the study. CRTIH following OHCA was defined as a traumatic intracranial injury from collapse due to sudden loss of consciousness associated with OHCA. Patients with and without CRTIH were compared. The primary outcome assessed was the frequency of CRTIH following OHCA. Additionally, the clinical features, management, and consequences of CRTIH were analyzed descriptively. RESULTS: CRTIH following OHCA was observed in 8 of 345 enrolled patients (2.3%). CRTIH was more frequent after collapse outside the home, from a standing position, or due to cardiac arrest with a cardiac etiology. Intracranial hematoma expansion on follow up CT was seen in 2 patients; both received anticoagulant therapy, and one required surgical evacuation. Three patients (37.5%) with CRTIH had favorable neurological outcomes 28 days after collapse. CONCLUSIONS: Despite its rare occurrence, physicians should pay special attention to CRTIH following OHCA during the post-resuscitation care period. Larger prospective studies are warranted to provide a more explicit picture of this clinical condition.

    DOI: 10.1016/j.resplu.2023.100418

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  • Attenuation of pulmonary damage in aged lipopolysaccharide-induced inflammation mice through continuous 2 % hydrogen gas inhalation: A potential therapeutic strategy for geriatric inflammation and survival. 国際誌

    Toshiyuki Aokage, Masumi Iketani, Mizuki Seya, Ying Meng, Kohei Ageta, Hiromichi Naito, Atsunori Nakao, Ikuroh Ohsawa

    Experimental gerontology   180   112270 - 112270   2023年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    INTRODUCTION: With the global population aging, there is an increased prevalence of sepsis among the elderly, a demographic particularly susceptible to inflammation. This study aimed to evaluate the therapeutic potential of hydrogen gas, known for its anti-inflammatory and antioxidant properties, in attenuating inflammation specifically in the lungs and liver, and age-associated molecular markers in aged mice. METHODS: Male mice aged 21 to 23 months, representative of the human elderly population, were subjected to inflammation via intraperitoneal injection of lipopolysaccharide (LPS). The mice were allocated into eight groups to examine the effects of varying durations and concentrations of hydrogen gas inhalation: control, saline without hydrogen, saline with 24-hour 2 % hydrogen, LPS without hydrogen, LPS with 24-hour 2 % hydrogen, LPS with 6-hour 2 % hydrogen, LPS with 1-hour 2 % hydrogen, and LPS with 24-hour 1 % hydrogen. Parameters assessed included survival rate, activity level, inflammatory biomarkers, and organ injury. RESULTS: Extended administration of hydrogen gas specifically at a 2 % concentration for 24 h led to a favorable prognosis in the aged mice by reducing mRNA expression of inflammatory biomarkers in lung and liver tissue, mitigating lung injury, and diminishing the expression of the senescence-associated protein p21. Moreover, hydrogen gas inhalation selectively ameliorated senescence-related markers in lung tissue, including C-X-C motif chemokine 2, metalloproteinase-3, and arginase-1. Notably, hydrogen gas did not alleviate LPS-induced liver injury under the conditions tested. CONCLUSION: The study highlights that continuous inhalation of hydrogen gas at a 2 % concentration for 24 h can be a potent intervention in the geriatric population for improving survival and physical activity by mitigating pulmonary inflammation and modulating senescence-related markers in aged mice with LPS-induced inflammation. This finding paves the way for future research into hydrogen gas as a therapeutic strategy to alleviate severe inflammation that can lead to organ damage in the elderly.

    DOI: 10.1016/j.exger.2023.112270

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  • Comparison of outcomes of out-of-hospital cardiac arrest patients: Emergency calls placed from mobile phones vs. landline phones. 国際誌

    Takeshi Nishimura, Masafumi Suga, Takashi Hongo, Tetsuya Yumoto, Atsunori Nakao, Satoshi Ishihara, Hiromichi Naito

    Resuscitation plus   15   100434 - 100434   2023年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Until recently, calls to the emergency medical service (EMS) from landline phones, which display the caller's exact location at the dispatch center, had been common. Since the use of mobile phones has become widespread, many emergency calls are now made from mobile phones. Differences in outcomes of out-of-hospital cardiac arrest (OHCA) patients for whom EMS was called from mobile versus landline phones has not yet been fully elucidated. METHODS: We performed a retrospective, population-based analysis in Kobe, Japan to examine whether EMS calls from mobiles improved the prognosis of OHCA patients over EMS calls placed from landlines. The primary outcome was favorable neurological outcome, defined as Cerebral Performance Category (CPC) scores of 1 or 2 at discharge. Secondary outcomes were survival at one-month, survival at discharge, and time durations between call and EMS activities. RESULTS: Of 4,231 OHCA cases, 2,194 cases (706 landline cases vs. 1,488 mobile cases) were included in this study. The percentages of favorable neurological outcomes were 0.7% (5/706) in the landline group and 3.8% (56/1,488) in the mobile group. Adjusted multivariable logistic regression revealed that favorable neurological outcomes (odds ratio [OR] 3.03, 95% confidence interval [CI] 1.12-8.17, p = 0.03) were better in the mobile group, while one-month survival (OR 1.30, 95% CI 0.80-2.14, p = 0.29) was not significantly different. Bystander CPR was more frequently administered in the mobile group (landlines 61.3% vs. mobiles 68.4%, p < 0.01). Time durations between call to EMS dispatch (184.5 [IQR 157-220 s] vs. 205 [IQR 174-248 s], p < 0.01) and EMS arrival (476.5 [IQR 377-599 s] vs. 491 [IQR 407.5-611.5 s], p < 0.01) were shorter in the landline group. CONCLUSIONS: Although the landline caller location display system seems effective for shorter times between EMS call and EMS arrival, mobile phone use was associated with better neurological outcomes.

    DOI: 10.1016/j.resplu.2023.100434

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  • An Unusual Presentation of Chest Pain and Laryngeal Discomfort in a Pregnant Woman: A Case Report and Literature Review.

    Misa Sasanami, Atsuyoshi Iida, Masaya Iwamuro, Ryousuke Hirai, Takashi Obara, Kohei Tsukahara, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao

    Acta medica Okayama   77 ( 4 )   429 - 431   2023年8月

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    記述言語:英語  

    Intramural esophageal dissection (IED), characterized by bleeding into the submucosal space, leads to mucosal separation and dissection. The most prevalent symptoms are sudden chest or retrosternal pain, hematemesis, and dysphagia. Therefore, acute coronary syndrome and aortic dissection are among its most notable differential diagnoses. A 31-year-old pregnant woman presented with acute chest pain, laryngeal discomfort, and hematemesis. Emergency esophagogastroscopy revealed longitudinal mucosal dissection (upper esophagus to esophagogastric junction). The patient was successfully treated by avoiding the ingestion of solid foods. Clinicians should consider a diagnosis of IED for pregnant patients with acute chest pain, especially if hematemesis is present.

    DOI: 10.18926/AMO/65755

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  • Transversal Survey of Emergency Medicine Policy and Quality Metrics in Japan's Regional Health Care Plans.

    Atsuyoshi Iida, Shinya Saito, Jun Hamada, Shunsuke Nakamura, Tsuyoshi Nojima, Hiromichi Naito, Takeshi Mikane

    JMA journal   6 ( 3 )   284 - 291   2023年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    INTRODUCTION: It is essential to establish appropriate medical quality metrics and make improvements to safely and efficiently deliver optimum emergency medical services. The Ministry of Health, Labor and Welfare (MHLW) recommends prefectures to establish numerical quality metrics in their regional healthcare plans (RHCP). The 7th RHCP was issued by the MHLW in 2017 along with a notice of planning in covering the six-year period from 2018 to 2023. In this descriptive study, the emergency medicine policies in the 7th RHCP of each prefecture were analyzed from a quality improvement perspective. METHOD: The authors examined the chapters on emergency medicine in the RHCPs of 47 prefectural governments for the overall structure, cost-benefits, and connection to community-based integrated care systems. The type and number of clinical measures listed as numerical metrics and their classification methods were emphasized. RESULT: Regarding the overall plan structure, 40 prefectural governments began their description with an analysis of current surroundings. In total, 24 prefectural governments mentioned community-based integrated care systems but none mentioned cost-benefit analysis. Altogether, only 43 of 47 prefectural governments (91%) indicated numerical metrics. The maximum number of numerical targets for quality measures by prefecture was 19, the minimum was 0, and the median was 4 (IQR: 3-6.5); there were 220 metrics in total, with 82 structural, 96 process, and 42 outcome measures. Additionally, 13 prefectures (28%) classified quality measures according to the MHLW's guidance, 6 (13%) used their own classification manner, while the others did not classify their measures. CONCLUSIONS: There were significant differences in emergency medicine policies and quality metrics among the prefectural governments. Further research is needed to develop and establish more comprehensive and appropriate metrics based on a common methodology to improve the quality of emergency medicine.

    DOI: 10.31662/jmaj.2022-0172

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  • 救急医療現場における個人的信念に基づく医療行為拒否への対応 放射線被曝拒否事例から考える

    小出 恭大, 湯本 哲也, 本郷 貴識, 小崎 吉訓, 野島 剛, 上田 浩平, 小原 隆史, 飯田 淳義, 山本 浩継, 青景 聡之, 塚原 紘平, 内藤 宏道, 中尾 篤典

    日本臨床救急医学会雑誌   26 ( 3 )   358 - 358   2023年7月

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    記述言語:日本語   出版者・発行元:(一社)日本臨床救急医学会  

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  • アセトアミノフェン中毒におけるプロカルシトニンの有用性

    野島 剛, 本郷 貴識, 小原 隆史, 小崎 吉訓, 飯田 淳義, 湯本 哲也, 青景 聡之, 塚原 紘平, 内藤 宏道, 中尾 篤典

    中毒研究   36 ( 2 )   207 - 207   2023年7月

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    記述言語:日本語   出版者・発行元:(株)へるす出版  

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  • Hydrogen inhalation attenuates lung contusion after blunt chest trauma in mice. 国際誌

    Kohei Ageta, Takahiro Hirayama, Toshiyuki Aokage, Mizuki Seya, Ying Meng, Tsuyoshi Nojima, Hirotsugu Yamamoto, Takafumi Obara, Atsunori Nakao, Tetsuya Yumoto, Kohei Tsukahara, Hiromichi Naito

    Surgery   2023年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Lung contusion caused by blunt chest trauma evokes a severe inflammatory reaction in the pulmonary parenchyma that may be associated with acute respiratory distress syndrome. Although hydrogen gas has antioxidant and anti-inflammatory effects and is protective against multiple types of lung injury at safe concentrations, the effects of inhaled hydrogen gas on blunt lung injury have not been previously investigated. Therefore, using a mouse model, we tested the hypothesis that hydrogen inhalation after chest trauma would reduce pulmonary inflammation and acute lung injury associated with lung contusion. METHODS: Inbred male C57BL/6 mice were randomly divided into 3 groups: sham with air inhalation, lung contusion with air inhalation, and lung contusion with 1.3% hydrogen inhalation. Experimental lung contusion was induced using a highly reproducible and standardized apparatus. Immediately after induction of lung contusion, mice were placed in a chamber exposed to 1.3% hydrogen gas in the air. Histopathological analysis and real-time polymerase chain reaction in lung tissue and blood gas analysis were performed 6 hours after contusion. RESULTS: Histopathological examination of the lung tissue after contusion revealed perivascular/intra-alveolar hemorrhage, perivascular/interstitial leukocyte infiltration, and interstitial/intra-alveolar edema. These histological changes and the extent of lung contusion, as determined by computed tomography, were significantly mitigated by hydrogen inhalation. Hydrogen inhalation also significantly reduced inflammatory cytokine and chemokine mRNA levels and improved oxygenation. CONCLUSION: Hydrogen inhalation therapy significantly mitigated inflammatory responses associated with lung contusion in mice. Hydrogen inhalation therapy may be a supplemental therapeutic strategy for treating lung contusion.

    DOI: 10.1016/j.surg.2023.04.029

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  • Furious lung abscess due to Parvimonas micra

    Shinnosuke Fukushima, Hideharu Hagiya, Hiromichi Naito, Fumio Otsuka

    Respirology Case Reports   11 ( 6 )   2023年5月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    DOI: 10.1002/rcr2.1161

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  • 症例ライブラリー 術中の頻脈 術前から原因不明の頻脈を伴った外傷患者

    小﨑 吉訓, 内藤 宏道

    LiSA   30 ( 5 )   570 - 572   2023年5月

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    出版者・発行元:株式会社医学書院  

    DOI: 10.11477/mf.3101202554

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  • Impact of frailty on long-term mortality in older patients receiving intensive care via the emergency department. 国際誌

    Mototaka Inaba, Hiromichi Naito, Takashi Yorifuji, Chikaaki Nakamichi, Hiroki Maeyama, Hideki Ishikawa, Nobuaki Shime, Sadayori Uemori, Satoshi Ishihara, Makoto Takaoka, Tsuyoshi Ohtsuka, Masahiro Harada, Satoshi Nozaki, Keisuke Kohama, Ryota Sakurai, Shuho Sato, Shun Muramatsu, Kazunori Yamashita, Toshihiko Mayumi, Kaoruko Aita, Atsunori Nakao

    Scientific reports   13 ( 1 )   5433 - 5433   2023年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    The aim of this study was to evaluate whether frailty was associated with 6-month mortality in older adults who were admitted to the intensive care unit (ICU) with an illness requiring emergency care. The investigation was a prospective, multi-center, observational study conducted among the ICUs of 17 participating hospitals. Patients ≥ 65 years of age who were admitted to the ICU directly from an emergency department visit were assessed to determine their baseline Clinical Frailty Scale (CFS) scores before the illness and were surveyed 6 months after admission. Among 650 patients included in the study, the median age was 79 years old, and overall mortality at 6 months was as low as 21%, ranging from 6.2% in patients with CFS 1 to 42.9% in patients with CFS ≥ 7. When adjusted for potential confounders, CFS score was an independent prognostic factor for mortality (one-point increase in CFS, adjusted risk ratio with 95% confidence interval 1.19 [1.09-1.30]). Quality of life 6 months after admission worsened as baseline CFS score increased. However, there was no association between total hospitalization cost and baseline CFS. CFS is an important predictor of long-term outcomes among critically ill older patients requiring emergent admission.

    DOI: 10.1038/s41598-023-32519-2

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  • Association between prehospital advanced life support by emergency medical services personnel and neurological outcomes among adult out-of-hospital cardiac arrest patients treated with extracorporeal cardiopulmonary resuscitation: A secondary analysis of the SAVE-J II study. 国際誌

    Tetsuya Yumoto, Takashi Hongo, Toru Hifumi, Akihiko Inoue, Tetsuya Sakamoto, Yasuhiro Kuroda, Takashi Yorifuji, Atsunori Nakao, Hiromichi Naito

    Journal of the American College of Emergency Physicians open   4 ( 2 )   e12948   2023年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    STUDY OBJECTIVE: Early deployment of extracorporeal cardiopulmonary resuscitation (ECPR) is critical in treating refractory out-of-hospital cardiac arrest (OHCA) patients who are potential candidates for ECPR. The effect of prehospital advanced life support (ALS), including epinephrine administration or advanced airway, compared with no ALS in this setting remains unclear. This study's objective was to determine the association between any prehospital ALS care and outcomes of patients who received ECPR with emergency medical services-treated OHCA. METHODS: This was a secondary analysis of data from the Study of Advanced Cardiac Life Support for Ventricular Fibrillation with Extracorporeal Circulation in Japan (SAVE-J) II study. Patients were separated into 2 groups-those who received prehospital ALS (ALS group) and those did not receive prehospital ALS (no ALS group). Multiple logistic regression analysis was used to investigate the association between prehospital ALS and favorable neurological outcomes (defined as Cerebral Performance Category scores 1-2) at hospital discharge. RESULTS: A total of 1289 patients were included, with 644 patients in the ALS group and 645 patients in the no ALS group. There were fewer favorable neurological outcomes at hospital discharge in the ALS group compared with the no ALS group (10.4 vs 19.8%, p <0.001). A multiple logistic regression analysis revealed that any prehospital ALS care (adjusted odds ratios 0.47; 95% confidence interval 0.34-0.66; p <0.001) was associated with unfavorable neurological outcomes at hospital discharge. CONCLUSION: Prehospital ALS was associated with worse neurological outcomes at hospital discharge in patients treated with ECPR for OHCA. Further prospective studies are required to determine the clinical implications of these findings.

    DOI: 10.1002/emp2.12948

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  • Hydrogen gas treatment improves survival in a rat model of crush syndrome by ameliorating rhabdomyolysis

    Tetsuya Yumoto, Toshiyuki Aokage, Takahiro Hirayama, Hirotsugu Yamamoto, Takafumi Obara, Tsuyoshi Nojima, Hiromichi Naito, Atsunori Nakao

    European Journal of Inflammation   21   1721727X2311685 - 1721727X2311685   2023年3月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:SAGE Publications  

    Objectives

    Crush syndrome (CS) is characterized by a systemic manifestation of traumatic rhabdomyolysis, leading to multiple organ dysfunction and death. Ischemia-reperfusion (IR) injury is commonly responsible for systemic response. Extending studies have shown that hydrogen gas treatment ameliorated IR injury in numerous experimental models; however, its effect on CS has not been well examined. This study aimed to investigate the effects of hydrogen gas inhalation following crush injury in an experimental model of CS.

    Methods

    Male Sprague-Dawley rats were subjected to experimental CS by applying a total of 3.0 kg weight to both hindlimb under general anesthesia for 6 h. Immediately after decompression, the animals were randomly placed in a gas chamber filled with either air or 1.3% hydrogen gas. Animals were sacrificed 18 h or 24 h following gas exposure for non-survival studies or for survival study, respectively.

    Results

    The rats with hydrogen treatment ( n = 6) had a higher 24-h survival than the rats with air treatment ( n = 9) (100% vs. 44%, p = 0.035). Lactate concentrations (2.9 ± 0.2 vs. 2.2 ± 0.2 mmol/L, p = 0.040) and creatine kinase (34,178 ± 13,580 vs. 5005 ± 842 IU/L, p = 0.016) were lower in the hydrogen group compared with the air group 18 h after decompression ( n = 4 in the air group, and n = 5 in the H2 group). Histological analysis revealed that the damage to the rectus femoris muscle and kidney appeared to be ameliorated by hydrogen treatment.

    Conclusion

    Hydrogen gas inhalation may be a promising therapeutic approach in the treatment of CS.

    DOI: 10.1177/1721727x231168547

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    その他リンク: http://journals.sagepub.com/doi/full-xml/10.1177/1721727X231168547

  • Heat Exposure Following the Rainy Season Is Associated With an Increased Risk of Cardiovascular Emergency Among the Elderly in Japan. 国際誌

    Ryohei Fujimoto, Etsuji Suzuki, Saori Kashima, Kazufumi Nakamura, Hiromichi Naito, Atsunori Nakao, Hiroshi Ito, Takashi Yorifuji

    Journal of the American Heart Association   12 ( 6 )   e027046   2023年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Background Despite the impact of heat exposure caused by global warming, few studies have investigated the hourly effects of heat exposure and the risk of cardiovascular disease (CVD) in the elderly. We examined the associations between short-term heat exposure and the risk of CVD in the elderly in Japan and evaluated possible effect-measure modifications by rainy seasons that occur in East Asia. Methods and Results We conducted a time-stratified case-crossover study. The study included 6527 residents in Okayama City, Japan, aged ≥65 years who were transported to emergency hospitals between 2012 and 2019 for the onset of CVD during and a few months after the rainy seasons. We examined the linear associations between temperature and CVD-related emergency calls for each year and for hourly preceding intervals before the emergency call during the most relevant months. Heat exposure during 1 month after the end of the rainy season was associated with CVD risk; the odds ratio (OR) for a 1° C increase in temperature was 1.34 (95% CI, 1.29-1.40). When we further explored the nonlinear association by using the natural cubic spline model, we found a J-shaped relationship. Exposures 0 to 6 hours before the case event (preceding intervals 0-6 hours) were associated with CVD risk, particularly for the preceding interval 0 to 1 hour (OR, 1.33 [95% CI, 1.28-1.39]). For longer periods, the highest risk was at preceding intervals 0 to 23 hours (OR, 1.40 [95% CI, 1.34-1.46]). Conclusions Elderly individuals may be more susceptible to CVD after heat exposure during the month after the rainy season. As shown by finer temporal resolution analyses, short-term exposure to increasing temperature can trigger CVD onset.

    DOI: 10.1161/JAHA.122.027046

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  • Association of Prehospital Physician Presence During Pediatric Out-of-Hospital Cardiac Arrest With Neurologic Outcomes. 国際誌

    Takafumi Obara, Tetsuya Yumoto, Tsuyoshi Nojima, Takashi Hongo, Kohei Tsukahara, Naomi Matsumoto, Takashi Yorifuji, Atsunori Nakao, Jonathan Elmer, Hiromichi Naito

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies   2023年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    OBJECTIVES: To examine the association of prehospital physician presence with neurologic outcomes of pediatric patients with out-of-hospital cardiac arrest (OHCA). DESIGN: Retrospective cohort study. SETTING: Data from the Japanese Association for Acute Medicine-OHCA Registry. INTERVENTIONS: None. PATIENTS: Pediatric patients (age 17 yr old or younger) registered in the database between June 2014 and December 2019. MEASUREMENT AND MAIN RESULTS: We used logistic regression models with stabilized inverse probability of treatment weighting (IPTW) to estimate the associated treatment effect of a prehospital physician with 1-month neurologically intact survival. Secondary outcomes included in-hospital return of spontaneous circulation (ROSC) and 1-month survival after OHCA. A total of 1,187 patients (276 in the physician presence group and 911 in the physician absence group) were included (median age 3 yr [interquartile range 0-14 yr]; 723 [61%] male). Comparison of the physician presence group, versus the physician absence, showed 1-month favorable neurologic outcomes of 8.3% (23/276) versus 3.6% (33/911). Physician presence was associated with greater odds of 1-month neurologically intact survival after stabilized IPTW adjustment (adjusted odds ratio [aOR] 1.98, 95% CI 1.08-3.66). We also found an association in the secondary outcome between physician presence, opposed to absence, and in-hospital ROSC (aOR 1.48, 95% CI 1.08-2.04). However, we failed to identify an association with 1-month survival (aOR 1.49, 95% CI 0.97-2.88). CONCLUSIONS: Among pediatric patients with OHCA, prehospital physician presence, compared with absence, was associated almost two-fold greater odds of 1-month favorable neurologic outcomes.

    DOI: 10.1097/PCC.0000000000003206

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  • Organ Donation after Extracorporeal Cardiopulmonary Resuscitation and Brain Death.

    Takafumi Obara, Tetsuya Yumoto, Kenji Aoshima, Kohei Tsukahara, Hiromichi Naito, Atsunori Nakao

    Acta medica Okayama   77 ( 1 )   117 - 120   2023年2月

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    記述言語:英語  

    A 38-year-old primipara Japanese woman suffered cardiac arrest due to a pulmonary thromboembolism 1 day after undergoing a cesarean section. Extracorporeal cardiopulmonary resuscitation was initiated and extracorporeal membrane oxygenation support was needed for 24 h. Despite intensive care, the patient was diagnosed with brain death on day 6. With the family's consent, comprehensive end-of-life care including organ donation was discussed based on our hospital's policy. The family decided to donate her organs. Specific training and education are required for emergency physicians to optimize the process of incorporating organ donation into end-of-life care while respecting the patient's and family's wishes.

    DOI: 10.18926/AMO/64372

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  • A Seat Belt Injury Causing a Large Breast Hematoma: A Case Report. 国際誌

    Shunki Yamamoto, Yoshinori Kosaki, Takenori Uehara, Hiromichi Naito, Atsunori Nakao

    Cureus   15 ( 2 )   e35440   2023年2月

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    記述言語:英語  

    Seat belts with shoulder restraints have decreased the frequency of life-threatening severe chest trauma caused by car accidents. However, the introduction of seat belt legislation has led to an increase in a specific pattern of blunt trauma known as seat belt syndrome, which includes rib, clavicle, spine, and sternum fractures, as well as rupture of hollow pelvic and abdominal viscera, mesenteric tears, and major vessel injuries. The shoulder restraint part of the three-point seat belt commonly rests near or over the female and male breast. A 54-year-old female presented to our emergency department complaining of swelling and pain in her left breast immediately after a traffic accident. The patient had used a seat belt with a shoulder restraint. Bruising was noted along her chest where there had been seat belt contact. Her breast hematoma was most likely caused by breast tissue compression between her rib and the seat belt. Contrast-enhanced computed tomography demonstrated a sizable breast hematoma with active arterial contrast material extravasation, as well as multiple left rib fractures. The patient was conservatively treated with analgesic and anti-inflammatory drugs. Complete resolution was achieved, and her breast returned to its normal appearance. Although endovascular treatment and surgical hemostasis have been proposed for the treatment of breast injuries with active bleeding, conservative treatment such as compression hemostasis may be feasible.

    DOI: 10.7759/cureus.35440

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  • 遺伝性血管浮腫(HAE)の診断後に、腹痛発作で救急搬送を繰り返していた一例

    佐々並 三紗, 薬師寺 泰匡, 本郷 貴識, 野島 剛, 上田 浩平, 内藤 宏道, 中尾 篤典

    日本腹部救急医学会雑誌   43 ( 2 )   520 - 520   2023年2月

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    記述言語:日本語   出版者・発行元:(一社)日本腹部救急医学会  

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  • Automatic emergency calls from smartphone/smartwatch applications in trauma. 国際誌

    Takashi Hongo, Shunki Yamamoto, Tsuyoshi Nojima, Hiromichi Naito, Atsunori Nakao, Tetsuya Yumoto

    Acute medicine & surgery   10 ( 1 )   e875   2023年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/ams2.875

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  • Successfully treated case of severe hypothermia secondary to myxedema coma. 国際誌

    Hirotsugu Yamamoto, Takashi Hongo, Tsuyoshi Nojima, Takafumi Obara, Yoshinori Kosaki, Kohei Ageta, Kohei Tsukahara, Tetsuya Yumoto, Atsunori Nakao, Hiromichi Naito

    Acute medicine & surgery   10 ( 1 )   e828   2023年

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    記述言語:英語  

    BACKGROUND: Myxedema coma is an extremely rare but fatal endocrine emergency that requires urgent recognition and treatment. We describe a case of severe hypothermia that rapidly deteriorated to cardiac arrest that was attributed to myxedema coma. CASE PRESENTATION: A 52-year-old man without a history of hypothyroidism was transferred to our emergency department due to coma and profound hypothermia. The patient developed cardiac arrest immediately after hospital arrival but return of spontaneous circulation was achieved shortly after resuscitation. The patient was noted to have generalized, nonpitting edema, dry skin, severe respiratory acidosis, hyponatremia, and elevated creatinine kinase, which was indicative of hypothyroidism. Myxedema coma was confirmed by a thyroid profile. The patient was successfully treated with intravenous levothyroxine and glucocorticoid. CONCLUSION: Although myxedema coma is a rare cause of severe hypothermia, emergency physicians should be familiar with its clinical features and management.

    DOI: 10.1002/ams2.828

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  • Association between timing of speech and language therapy initiation and outcomes among post-extubation dysphagia patients: a multicenter retrospective cohort study

    Takashi Hongo, Ryohei Yamamoto, Keibun Liu, Takahiko Yaguchi, Hisashi Dote, Ryusuke Saito, Tomoyuki Masuyama, Kosuke Nakatsuka, Shinichi Watanabe, Takahiro Kanaya, Tomoya Yamaguchi, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao

    Critical Care   26 ( 1 )   2022年12月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Springer Science and Business Media LLC  

    Abstract

    Background

    Post-extubation dysphagia (PED) is recognized as a common complication in the intensive care unit (ICU). Speech and language therapy (SLT) can potentially help improve PED; however, the impact of the timing of SLT initiation on persistent PED has not been well investigated. This study aimed to examine the timing of SLT initiation and its effect on patient outcomes after extubation in the ICU.

    Methods

    We conducted this multicenter, retrospective, cohort study, collecting data from eight ICUs in Japan. Patients aged ≥ 20 years with orotracheal intubation and mechanical ventilation for longer than 48 h, and those who received SLT due to PED, defined as patients with modified water swallowing test scores of 3 or lower, were included. The primary outcome was dysphagia at hospital discharge, defined as functional oral intake scale score &lt; 5 or death after extubation. Secondary outcomes included dysphagia or death at the seventh, 14th, or 28th day after extubation, aspiration pneumonia, and in-hospital mortality. Associations between the timing of SLT initiation and outcomes were determined using multivariable logistic regression.

    Results

    A total of 272 patients were included. Of them, 82 (30.1%) patients exhibited dysphagia or death at hospital discharge, and their time spans from extubation to SLT initiation were 1.0 days. The primary outcome revealed that every day of delay in SLT initiation post-extubation was associated with dysphagia or death at hospital discharge (adjusted odds ratio (AOR), 1.09; 95% CI, 1.02–1.18). Similarly, secondary outcomes showed associations between this per day delay in SLT initiation and dysphagia or death at the seventh day (AOR, 1.28; 95% CI, 1.05–1.55), 14th day (AOR, 1.34; 95% CI, 1.13–1.58), or 28th day (AOR, 1.21; 95% CI, 1.07–1.36) after extubation and occurrence of aspiration pneumonia (AOR, 1.09; 95% CI, 1.02–1.17), while per day delay in post-extubation SLT initiation did not affect in-hospital mortality (AOR, 1.04; 95% CI, 0.97–1.12).

    Conclusions

    Delayed initiation of SLT in PED patients was associated with persistent dysphagia or death. Early initiation of SLT may prevent this complication post-extubation. A randomized controlled study is needed to validate these results.

    DOI: 10.1186/s13054-022-03974-6

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    その他リンク: https://link.springer.com/article/10.1186/s13054-022-03974-6/fulltext.html

  • Rare case of intracerebral hemorrhage in anaphylactic shock following administration of intramuscular adrenaline: A case report. 国際誌

    Shunki Yamamoto, Takashi Hongo, Tomokazu Tamura, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao

    Clinical case reports   10 ( 11 )   e6534   2022年11月

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    記述言語:英語  

    Intracerebral hemorrhage should be considered as a possible adverse event in patients with anaphylactic shock who are treated with adrenaline administration, especially in those at high risk of serious bleeding events.

    DOI: 10.1002/ccr3.6534

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  • 認知機能および(または)摂食嚥下機能の障害予防を目指すICU早期リハビリテーション 人工呼吸管理後の嚥下障害におけるST介入時期の検討 多施設後ろ向き観察研究(中間報告)

    本郷 貴識, 山本 良平, 劉 啓文, 内藤 宏道, 中尾 篤典, 水川 俊一

    日本集中治療医学会雑誌   29 ( Suppl.1 )   373 - 373   2022年11月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • Bile pigments in emergency and critical care medicine. 国際誌

    Mizuki Seya, Toshiyuki Aokage, Tsuyoshi Nojima, Atsunori Nakao, Hiromichi Naito

    European journal of medical research   27 ( 1 )   224 - 224   2022年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Bile pigments, such as bilirubin and biliverdin, are end products of the heme degradation pathway in mammals and are widely known for their cytotoxic effects. However, recent studies have revealed that they exert cytoprotective effects through antioxidative, anti-inflammatory, and immunosuppressive properties. All these mechanisms are indispensable in the treatment of diseases in the field of emergency and critical care medicine, such as coronary ischemia, stroke, encephalomyelitis, acute lung injury/acute respiratory distress syndrome, mesenteric ischemia, and sepsis. While further research is required before the safe application of bile pigments in the clinical setting, their underlying mechanisms shed light on their utilization as therapeutic agents in the field of emergency and critical care medicine. This article aims to summarize the current understanding of bile pigments and re-evaluate their therapeutic potential in the diseases listed above.

    DOI: 10.1186/s40001-022-00863-0

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  • Predictive Factors of Return Home and Return to Work for Intensive Care Unit Survivors after Traumatic Brain Injury with a Follow-up Period of 2 Years.

    Satoru Yabuno, Takao Yasuhara, Satoshi Murai, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao, Isao Date

    Neurologia medico-chirurgica   62 ( 10 )   465 - 474   2022年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Intensive care unit (ICU) survivors after traumatic brain injury (TBI) frequently have serious disabilities with subsequent difficulty in reintegration into society. We aimed to investigate outcomes for ICU survivors after moderate to severe TBI (msTBI) and to identify predictive factors of return home (RH) and return to work (RTW). This single-center retrospective cohort study was conducted on all trauma patients admitted to the emergency ICU of our hospital between 2013 and 2017. Of these patients, adult (age ≥ 18 years) msTBI patients with head Abbreviated Injury Scale ≥ 3 were extracted. We performed univariate/multivariate logistic regression analyses to explore the predictive factors of RH and RTW. Among a total of 146 ICU survivors after msTBI, 107 were included (median follow-up period: 26 months). The RH and RTW rates were 78% and 35%, respectively. Multivariate analyses revealed that the predictive factors of RH were age < 65 years (P < 0.001), HR < 76 bpm (P = 0.015), platelet count ≥ 19× 104/μL (P = 0.0037), D-dimer < 26 μg/mL (P = 0.034), and Glasgow Coma Scale (GCS) score > 8 (P = 0.0015). Similarly, the predictive factors of RTW were age < 65 years (P < 0.001) and GCS score > 8 (P = 0.0039). This study revealed that "age" and "GCS score on admission" affected RH and RTW for ICU survivors after msTBI.

    DOI: 10.2176/jns-nmc.2022-0149

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  • 縦隔気腫を合併した糖尿病性ケトアシドーシスの1例

    山下 航矢, 本郷 貴識, 野島 剛, 湯本 哲也, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   33 ( 10 )   881 - 881   2022年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • Luminal administration of biliverdin ameliorates ischemia-reperfusion injury following intestinal transplant in rats. 国際誌

    Tsuyoshi Nojima, Takafumi Obara, Hirotsugu Yamamoto, Tetsuya Yumoto, Takuro Igawa, Toshiyuki Aokage, Mizuki Seya, Atsunori Nakao, Hiromichi Naito

    Surgery   172 ( 5 )   1522 - 1528   2022年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Intestinal grafts are susceptible to ischemia-reperfusion injury, resulting in the loss of mucosal barrier function and graft failure. Biliverdin is known to exert a variety of cytoprotective functions against oxidative tissue injury. Because the mucosal layer is the primary site of ischemia-reperfusion injury, mucosa-targeting strategies by luminal delivery of reagents might be beneficial. We tested whether intraluminal administration of biliverdin as an adjuvant to standard preservation solutions protected against ischemia-reperfusion injury. METHODS: Orthotopic syngeneic intestinal transplants were performed on Lewis rats after 6 hours of cold preservation. Saline containing biliverdin (10 μM) or without biliverdin was introduced into the lumen of the intestinal grafts immediately before cold preservation. RESULTS: Damage to the intestinal mucosa caused by ischemia-reperfusion injury resulted in severe morphological changes, including blunting of the villi and erosion, and led to significant loss of gut barrier function 3 hours after reperfusion. These changes to the mucosa were notably ameliorated by intraluminal administration of biliverdin. Biliverdin also effectively inhibited upregulation of messenger RNAs for interleukin-6, inducible nitric oxide synthase, and C-C motif chemokine 2. Additionally, biliverdin treatment prevented the loss of expression of claudin-1, a transmembrane, tight-junction barrier protein. The 14-day survival of recipients of biliverdin-treated grafts was significantly improved as compared with the recipients of saline-treated control grafts (83.3% vs 38.9%, P = .030). CONCLUSION: This study demonstrated that luminally delivered biliverdin provides beneficial effects during the transplant of rat small intestinal grafts and could be an attractive therapeutic option in organ transplantation.

    DOI: 10.1016/j.surg.2022.07.021

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  • 委員会報告 脳死下臓器提供におけるアンケート調査 脳死判定を目的とした転院搬送の考察をふまえて

    横堀 將司, 横田 裕行, 渥美 生弘, 黒田 泰弘, 内藤 宏道, 西山 慶, 林 宗博, 平尾 朋仁, 本多 ゆみえ, 師岡 誉也, 吉川 美喜子, 稲田 眞治, 小野 元, 伊藤 友弥, 江川 裕子, 沢本 圭悟, 岩永 航, 一般社団法人日本救急医学会脳死・臓器組織移植に関する委員会

    日本救急医学会雑誌   33 ( 8 )   421 - 435   2022年8月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

    新型コロナウイルス感染症蔓延下において脳死下臓器提供数が減少しているなかで,脳死判定を目的とした転院搬送の是非に関する議論が始まっている。これをふまえ,全国救命センターにおけるコロナ禍での脳死判定や脳死下臓器移植に関わる現状と問題点を調査した。全国救命センター295施設に質問紙URLを送付し電子的に回収した。調査項目は施設背景,臓器提供の意思決定に関する質問,臓器提供も見据えた患者管理,脳死判定,臓器提供手術の問題点に関する質問,臓器提供を目的とした転院に関する質問とした。220施設より回答を得た(回答率74.6%)。コロナ禍において臓器提供を施行した施設は45施設(20.5%)存在した。臓器提供を行った施設とそうでなかった施設において,休日夜間帯に勤務をしている専門医数に差が見られた(平均3.04人対2.44人)。また,コロナ禍によって臓器提供に関する事項が影響を受けたと回答した施設は全国救命センターの43施設(19.6%)に及び,患者個室管理,家族の面会制限,チームの参集困難など,感染対策による影響と回答した施設がうち39施設(90.7%)に見られた。「脳死下臓器提供」を目的とした転院に関し,他施設に転送したいと回答した施設群(60施設:27%)は,院内連携が手薄く,マンパワーが少なく,また,脳死判定医が少ないこと,脳死判定の費用に関わる経済的問題に要因があると思われた。本研究によりコロナ禍における脳死下臓器提供に関わるハード,ソフト両面の課題が明確になった。とくに施設におけるマンパワー拡充のための施設間連携と経済的支援の拡充が今後の課題であると思われた。(著者抄録)

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  • Frequency, associated factors, and associated outcomes of dysphagia following sepsis. 国際誌

    Takashi Hongo, Tetsuya Yumoto, Hiromichi Naito, Toshifumi Fujiwara, Jun Kondo, Satoshi Nozaki, Atsunori Nakao

    Australian critical care : official journal of the Confederation of Australian Critical Care Nurses   2022年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Identifying dysphagia as a potential complication of sepsis may improve swallowing function and survival while decreasing hospital length of stay. OBJECTIVES: Our goal was to determine the frequency of dysphagia in sepsis survivors on the 7th day after admission, as well as their associated factors and outcomes. METHODS: This single-centre, retrospective, observational study analysed data from sepsis survivors admitted to Okayama Saiseikai General Hospital from 2018 to 2019. Participants with sepsis were assigned to one of two study groups based on the presence or absence of dysphagia using the criterion of Functional Oral Intake Scale score <5 on the 7th day after admission. We used multivariate logistic regression to determine factors independently associated with dysphagia on the 7th day after admission. Multivariate logistic regression was also used to determine associations between groups and outcomes, including dysphagia on hospital discharge, direct discharge home (discharge of patients directly to their home), and total dependency (Barthel Index score ≤20) on hospital discharge. RESULTS: One hundred one patients met the study inclusion criteria, 55 with dysphagia and 46 without dysphagia. Fasting period (adjusted odds ratio [AOR]: 1.31, 95% confidence interval [CI]: 1.07-1.59) and enteral tube feeding (AOR: 8.56, 95% CI: 1.95-37.5) were independently associated with the presence of dysphagia on the 7th day after admission. Dysphagia on the 7th day after admission was associated with dysphagia on hospital discharge (AOR: 46.0, 95%, CI: 7.90-268.3), a lower chance of direct discharge home (AOR: 0.03, 95% CI: 0.01-0.15), and a higher incidence of total dependency (AOR: 9.30, 95% CI: 2.68-32.2). CONCLUSIONS: We found that dysphagia was commonly encountered post sepsis. Fasting period and enteral tube feeding were independently associated with dysphagia on the 7th day after admission. Dysphagia on the 7th day after admission was also associated with dysphagia on hospital discharge, nondirect discharge home, and dependency in activities of daily living at the time of hospital discharge.

    DOI: 10.1016/j.aucc.2022.06.003

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  • The Impact of Medical Students Teaching Basic Life Support to Laypersons.

    Yoshinori Kosaki, Hiromichi Naito, Atsuyoshi Iida, Hiromi Ihoriya, Tsuyoshi Nojima, Taihei Yamada, Hirotsugu Yamamoto, Shunsuke Nakamura, Yasuhiro Mandai, Atsunori Nakao

    Acta medica Okayama   76 ( 3 )   265 - 271   2022年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Basic life support (BLS) courses for laypersons, including cardiopulmonary resuscitation (CPR) training, is known to improve outcomes of out-of-hospital cardiac events. We asked medical students to provide BLS training for laypersons as a part of their emergency medicine education and evaluated the effects of training on the BLS skills of laypersons. We also used a questionnaire to determine whether the medical students who provided the BLS training were themselves more confident and motivated to perform BLS compared to students who did not provide BLS training. The proportions of laypersons who reported confidence in checking for a response, performing chest compressions, and automated external defibrillator (AED) use were significantly increased after the BLS training. The proportions of medical students who reported increased confidence/motivation in terms of understanding BLS, checking for a response, chest compression, use of AED, and willingness to perform BLS were significantly greater among medical students who provided BLS instructions compared to those who did not. BLS instruction by medical students was associated with an improvement in laypersons' CPR accuracy and confidence in responding to cardiac arrest. The results indicate that medical students could gain understanding, confidence, and motivation in regard to their BLS skills by teaching BLS to laypersons.

    DOI: 10.18926/AMO/63720

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  • Prehospital emergency life-saving technicians promote the survival of trauma patients: A retrospective cohort study. 国際誌

    Takeshi Nishimura, Tsuyoshi Nojima, Hiromichi Naito, Satoshi Ishihara, Shinichi Nakayama, Atsunori Nakao

    The American journal of emergency medicine   56   218 - 222   2022年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    OBJECTIVE: Appropriate decisions by medical technicians at a trauma scene may influence a patient's prognosis. Emergency life-saving technicians (ELSTs) are certified specialists trained with the knowledge to provide advanced techniques for prehospital emergency care in Japan. However, the benefit of treatment by ELSTs compared to basic emergency medical technicians (BEMTs) remains unclear. The aim of this study is to determine whether treatment by ELSTs improves outcomes for trauma patients. METHODS: We retrospectively reviewed the Japan Trauma Data Bank for the years 2004 to 2017. Patients transferred to the hospital directly from the trauma scene and at least 16 years old were included in this study. The following criteria were used to exclude patients; presence of burns, untreatable severe traumas, unknown ELST attendance, and missing prognosis. We compared two groups (ELST group: patients transported by emergency medical services (EMS) with the presence of at least one ELST; BEMT group: patients transported only by BEMTs). Primary outcome was survival to discharge. Secondary outcomes were the need of definitive treatments defined by surgical intervention, intravascular radiology and blood transfusion at the receiving hospital within 24 h. A multivariable logistic regression model was used to calculate odds ratio (OR) and confidence intervals (CI) adjusted by age, sex, revised trauma score, and Injury severity score (ISS). RESULTS: Overall survival to discharge did not improve significantly (adjusted OR 1.13, 95% CI 0.99-1.30) with ELST intervention. In-hospital blood transfusion was more frequently required in the ELST group (adjusted OR 1.10, 95% CI 1.01-1.20). Emergency interventions (adjusted OR 1.03, 95% CI 0.97-1.09) were not different between the groups. In stratified analysis, the benefit of ELST attendance for survival was observed among patients with ISS <16 (adjusted OR 1.53, 95% CI 1.10-2.15), aged 65 years or older (adjusted OR 1.27, 95% CI 1.07-1.52), during the earlier study period (2004-2008, adjusted OR 1.50, 95% CI 1.14-1.97), and shorter transportation time (adjusted OR 1.21, 95% CI 1.03-1.41). CONCLUSIONS: Dispatch systems with ELST should be considered for trauma transports, which may benefit elderly or moderate severity trauma groups, with shorter transportation time conditions.

    DOI: 10.1016/j.ajem.2022.04.004

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  • Thoracic vertebral fractures and azygos or hemiazygos vein injuries during cardiopulmonary resuscitation: Caution needed. 国際誌

    Tsuyoshi Nojima, Tetsuya Yumoto, Hiromichi Naito, Atsunori Nakao

    Resuscitation plus   10   100261 - 100261   2022年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.resplu.2022.100261

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  • Extracorporeal cardiopulmonary resuscitation in adult patients with out-of-hospital cardiac arrest: a retrospective large cohort multicenter study in Japan. 国際誌

    Akihiko Inoue, Toru Hifumi, Tetsuya Sakamoto, Hiroshi Okamoto, Jun Kunikata, Hideto Yokoi, Hirotaka Sawano, Yuko Egawa, Shunichi Kato, Kazuhiro Sugiyama, Naofumi Bunya, Takehiko Kasai, Shinichi Ijuin, Shinichi Nakayama, Jun Kanda, Seiya Kanou, Toru Takiguchi, Shoji Yokobori, Hiroaki Takada, Kazushige Inoue, Ichiro Takeuchi, Hiroshi Honzawa, Makoto Kobayashi, Tomohiro Hamagami, Wataru Takayama, Yasuhiro Otomo, Kunihiko Maekawa, Takafumi Shimizu, Satoshi Nara, Michitaka Nasu, Kuniko Takahashi, Yoshihiro Hagiwara, Shigeki Kushimoto, Reo Fukuda, Takayuki Ogura, Shin-Ichiro Shiraishi, Ryosuke Zushi, Norio Otani, Migaku Kikuchi, Kazuhiro Watanabe, Takuo Nakagami, Tomohisa Shoko, Nobuya Kitamura, Takayuki Otani, Yoshinori Matsuoka, Makoto Aoki, Masaaki Sakuraya, Hideki Arimoto, Koichiro Homma, Hiromichi Naito, Shunichiro Nakao, Tomoya Okazaki, Yoshio Tahara, Yasuhiro Kuroda

    Critical care (London, England)   26 ( 1 )   129 - 129   2022年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: The prevalence of extracorporeal cardiopulmonary resuscitation (ECPR) in patients with out-of-hospital cardiac arrest (OHCA) has been increasing rapidly worldwide. However, guidelines or clinical studies do not provide sufficient data on ECPR practice. The aim of this study was to provide real-world data on ECPR for patients with OHCA, including details of complications. METHODS: We did a retrospective database analysis of observational multicenter cohort study in Japan. Adult patients with OHCA of presumed cardiac etiology who received ECPR between 2013 and 2018 were included. The primary outcome was favorable neurological outcome at hospital discharge, defined as a cerebral performance category of 1 or 2. RESULTS: A total of 1644 patients with OHCA were included in this study. The patient age was 18-93 years (median: 60 years). Shockable rhythm in the initial cardiac rhythm at the scene was 69.4%. The median estimated low flow time was 55 min (interquartile range: 45-66 min). Favorable neurological outcome at hospital discharge was observed in 14.1% of patients, and the rate of survival to hospital discharge was 27.2%. The proportions of favorable neurological outcome at hospital discharge in terms of shockable rhythm, pulseless electrical activity, and asystole were 16.7%, 9.2%, and 3.9%, respectively. Complications were observed during ECPR in 32.7% of patients, and the most common complication was bleeding, with the rates of cannulation site bleeding and other types of hemorrhage at 16.4% and 8.5%, respectively. CONCLUSIONS: In this large cohort, data on the ECPR of 1644 patients with OHCA show that the proportion of favorable neurological outcomes at hospital discharge was 14.1%, survival rate at hospital discharge was 27.2%, and complications were observed during ECPR in 32.7%.

    DOI: 10.1186/s13054-022-03998-y

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  • Can Blood Ammonia Level, Prehospital Time, and Return of Spontaneous Circulation Predict Neurological Outcomes of Out-of-Hospital Cardiac Arrest Patients? A Nationwide, Retrospective Cohort Study. 国際誌

    Tsuyoshi Nojima, Hiromichi Naito, Takafumi Obara, Kohei Ageta, Hiromasa Yakushiji, Tetsuya Yumoto, Noritomo Fujisaki, Atsunori Nakao

    Journal of clinical medicine   11 ( 9 )   2022年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: This study aimed to test if blood ammonia levels at hospital arrival, considering prehospital time and the patient's condition (whether return of spontaneous circulation [ROSC] was achieved at hospital arrival), can predict neurological outcomes after out-of-hospital cardiac arrest (OHCA). METHODS: This was a retrospective cohort study on data from a nationwide OHCA registry in Japan. Patients over 17 years old and whose blood ammonia levels had been recorded were included. The primary outcome was favorable neurological outcome at 30 days after OHCA. Blood ammonia levels, prehospital time, and the combination of the two were evaluated using the receiver operating characteristic curve to predict favorable outcomes. Then, cut-off blood ammonia values were determined based on whether ROSC was achieved at hospital arrival. RESULTS: Blood ammonia levels alone were sufficient to predict favorable outcomes. The overall cut-off ammonia value for favorable outcomes was 138 μg/dL; values were different for patients with ROSC (96.5 μg/dL) and those without ROSC (156 μg/dL) at hospital arrival. CONCLUSIONS: Our results using patient data from a large OHCA registry showed that blood ammonia levels at hospital arrival can predict neurological outcomes, with different cut-off values for patients with or without ROSC at hospital arrival.

    DOI: 10.3390/jcm11092566

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  • 智の探求:プレホスピタルと医療機関における心肺蘇生を望まない患者への対応 DNAR指示を有する院外心停止の特徴、病院前処置、転機に関する検討

    田邉 綾, 内藤 宏道, 野島 剛, 塚原 紘平, 山田 太平, 中尾 篤典

    日本臨床救急医学会雑誌   25 ( 2 )   275 - 275   2022年5月

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    記述言語:日本語   出版者・発行元:(一社)日本臨床救急医学会  

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  • Emotional work stress reactions of emergency medical technicians involved in transporting out-of-hospital cardiac arrest patients with “do not attempt resuscitation” orders

    Ryo Tanabe, Takashi Hongo, Yasuhiro Mandai, Mototaka Inaba, Takashi Yorifuji, Atsunori Nakao, Jonathan Elmer, Hiromichi Naito

    Resuscitation   173   61 - 68   2022年4月

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    掲載種別:研究論文(学術雑誌)  

    Background: Emergency medical technicians (EMTs) may be subjected to emotional stress during patient treatment/transport. In Japan, dispatched EMTs must attempt resuscitation in all cases of out-of-hospital cardiac arrest (OHCA), including patients with “do not attempt resuscitation” (DNAR) orders and patients whose families do not support resuscitation. We described the characteristics, prevalence, and outcomes of OHCA/DNAR patients, and aimed to identify factors associated with EMT stress when treating them. Methods: We included OHCA patients transported by EMTs in the city of Okayama from 2015 to 2019. We identified patients with DNAR orders based on emergency medical service (EMS) records, then EMTs completed questionnaires regarding the management of those patients and EMTs’ emotions. Results: Among 3079 eligible OHCA patients, 122 patients (4%) had DNAR orders (DNAR group), and 2957 (96%) patients had no DNAR orders (no DNAR group). Based on responses from 243 EMT participants involved in OHCA/DNAR transports, we divided EMTs into high stress (73/243, 30%) and low stress (170/243, 70%) groups. EMTs experienced emotional stress from treating patients with family physician orders to transport (AOR: 4.74, 95% CI: 2.35–9.56) and those for whom prehospital defibrillation was performed (AOR: 20.7, 95% CI: 3.10–137.9). Conclusions: Approximately 30% of EMTs providing resuscitation to OHCA/DNAR patients experienced high levels of stress. Establishment of a prehospital emergency system incorporating physician medical direction and updated guidelines for treating patients with DNAR orders may reduce the psychosocial stress of EMTs.

    DOI: 10.1016/j.resuscitation.2022.01.028

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  • Impact of different medical direction policies on prehospital advanced airway management for out-of hospital cardiac arrest patients: A retrospective cohort study. 国際誌

    Takashi Hongo, Tetsuya Yumoto, Hiromichi Naito, Takeshi Mikane, Atsunori Nakao

    Resuscitation plus   9   100210 - 100210   2022年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: Although optimal prehospital airway management after out-of-hospital cardiac arrest (OHCA) remains undetermined, no studies have compared different advanced airway management (AAM) policies adopted by two hospitals in charge of online medical direction by emergency physicians. We examined the impact of two different AAM policies on OHCA patient survival. METHODS: This observational cohort study included adult OHCA patients treated in Okayama City from 2013 to 2016. Patients were divided into two groups: the O group - those treated on odd days when a hospital with a policy favoring laryngeal tube ventilation (LT) supervised, and the E group - those treated on even days when the other hospital with a policy favoring endotracheal intubation (ETI) supervised. Multiple logistic regression analysis was performed to assess airway device effects. The primary outcome measure was seven-day survival. RESULTS: Of 2,406 eligible patients, 50.1% were in the O group and 49.9% were in the E group. O group patients received less ETI (1.0% vs. 12.0%) and more LT (53.3% vs. 43.0%) compared with E group patients. In univariate analysis, no differences were observed in seven-day survival (9.4% vs 10.1%). Multiple regression analysis revealed neither LT nor ETI had a significant independent effect on seven-day survival, considering bag-valve mask ventilation as a reference (OR, 0.78; 95% CI, 0.54 to 1.13, OR, 0.79; 95% CI, 0.36 to 1.72, respectively). CONCLUSION: Despite different advanced airway medical direction policies in a single city, there were no substantial impact on outcomes for OHCA patients.

    DOI: 10.1016/j.resplu.2022.100210

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  • Reusable Medical Isolation Gowns with a Liquid Barrier: Washing Gowns in the Coronavirus Disease 2019 Pandemic Era?

    Hiromichi Naito, Kohei Tsukahara, Soshi Takao, Takashi Yorifuji, Atsunori Nakao

    JMA journal   5 ( 1 )   107 - 108   2022年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Healthcare providers are at risk of exposure to SARS-CoV-2 via droplets, respiratory secretions, and contact with contaminated surfaces. Personal protective equipment (PPE) is necessary for primary reliable prevention to treat patients with coronavirus disease 2019 (COVID-19). However, PPE shortages have had a significant impact on every medical facility, and outpatient clinics are especially vulnerable to shortages of medical supplies. During the first stage of the pandemic, efforts were made to reduce the use of medical supplies. Guidance and strategies were proposed to ration the use of PPE, including reusing it. However, reuse (wash) of isolation gowns has not been practically promoted despite these suggestions. Further, reusable products may have advantages for economic and ecologic reasons. We developed an adult universally sized, long-sleeved, 100% polyester, reusable/washable gown with liquid barrier protection. The isolation gown can be worn repeatedly through washing and subsequent disinfection, and it can withstand washing in 80°C hot water for 10 min and/or immersion in 0.05%-0.1% sodium hypochlorite for 30 min and then dried. This new gown's liquid barrier performance is at Association for the Advancement of Medical Instrumentation level 1, even after 20 repeated uses with low cost. The choice of barrier level for gowns should be made based on the risk of contamination. However, the healthcare setting for COVID-19 patients varies greatly with not fully elucidated transmissibility. The newly made reusable isolation gown can be one option for treating COVID-19 patients especially in low-risk settings with economical advantage. Further, preparedness for reuse may have critical implications in extreme shortage. Reconsideration should be focused on reusable gowns with liquid barrier performance and their appropriate use.

    DOI: 10.31662/jmaj.2021-0075

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  • Adult Scurvy Presenting with Painful Purpura on the Legs

    Nayu Tamura, Takafumi Obara, Taihei Yamada, Tsuyoshi Nojima, Shunsuke Nakamura, Yasuhiro Koide, Makoto Takaoka, Hiromichi Naito, Atsunori Nakao

    Internal Medicine   61 ( 12 )   1913 - 1916   2022年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Japanese Society of Internal Medicine  

    Prolonged vitamin C deficiency can result in numerous metabolic abnormalities like impaired tissue repair and defective collagen synthesis. This case report describes a middle-age Japanese man presenting painful purpura on his lower limbs, severe anemia, and altered consciousness. The patient had been eating a selective diet lacking in vegetables and fruits since childhood. A serum analysis demonstrated a low level of vitamin C. The patient was treated with vitamin supplementation and psychological intervention. Scurvy is an under-considered illness with a favorable prognosis if diagnosed early while it is still sporadically encountered in some patients with malabsorption or malnutrition even in modern times.

    DOI: 10.2169/internalmedicine.8409-21

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  • Geriatric trauma prognosis trends over 10 years: analysis of a nationwide trauma registry. 国際誌

    Takeshi Nishimura, Hiromichi Naito, Atsunori Nakao, Shinichi Nakayama

    Trauma surgery & acute care open   7 ( 1 )   e000735   2022年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    PURPOSE: With Japan's population rapidly skewing toward aging, the number of geriatric trauma patients is expected to increase. Since we need to continue to improve the quality of geriatric trauma patient care, this study aimed to evaluate in-hospital mortality trends among geriatric trauma patients in Japan over a recent 10-year period. METHODS: This was a retrospective cohort study of data from a Japanese nationwide trauma registry (the Japan National Trauma Data Bank) on patients admitted between January 1, 2008 and December 31, 2017. Geriatric patients were defined as those 65 years old and older. The primary outcome was to clarify in-hospital mortality trends and changes over these 10 years. RESULTS: We identified 265 268 eligible trauma patients. Excluding those under 65 years old and those with inadequate or unknown age data, missing prognosis, out-of-hospital cardiac arrest, and burns, 107 766 patients were enrolled in this study. The total trauma patient in-hospital mortality trend was evaluated using the Cochran-Armitage test and showed a significant decrease (p<0.001). Although severe trauma patients (Injury Severity Score (ISS) ≥16) showed a significant decreasing trend (p<0.001) over time (from 26.1% to 14.5%), less-severe trauma patients (ISS <16) did not (p=0.41) (from 2.7% to 2.1%). Mixed logistic regression analysis showed that the number of year patients stayed in the hospital was significantly associated with mortality. CONCLUSIONS: While recognizing the limitations of the current analysis, our data demonstrated that prognoses for severe trauma patients over 65 years old improved dramatically over these 10 years, especially in those with severe trauma. LEVEL OF EVIDENCE: Ⅲ-retrospective cohort study.

    DOI: 10.1136/tsaco-2021-000735

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  • Prehospital advanced airway management of emergency medical service-witnessed traumatic out-of-hospital cardiac arrest patients: analysis of nationwide trauma registry. 国際誌

    Takeshi Nishimura, Masafumi Suga, Atsunori Nakao, Satoshi Ishihara, Hiromichi Naito

    Acute medicine & surgery   9 ( 1 )   e786   2022年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    AIM: Survival of traumatic out-of-hospital cardiac arrest (OHCA) is poor. Early use of advanced airway management (AAM) techniques, including endotracheal intubation and supraglottic devices, are expected to contribute to the improved survival of these patients. The aim of this study was to determine whether prehospital use of AAM improves the outcomes for emergency medical service (EMS)-witnessed traumatic OHCA. METHODS: A nationwide retrospective study was carried out. Trauma patients with EMS-witnessed cardiac arrest who received cardiopulmonary resuscitation during transport were included. Patients younger than 16 years and those with missing data were excluded. We compared two groups using propensity score matching. The primary outcome was survival to discharge. The secondary outcome was return of spontaneous circulation (ROSC) on hospital arrival. A logistic regression model was used to calculate odds ratios (OR) and confidence intervals (CI). RESULTS: After propensity score matching, 1,346 patients were enrolled (AAM 673 versus non-AAM 673). Forty-four AAM cases (6.5%) and 39 non-AAM cases (5.8%) survived. Logistic regression analysis did not show a contribution of AAM for survival to discharge (AAM 44/673 (6.5%), non-AAM 39/673 (5.8%); OR 1.12; 95% CI, 0.70-1.76; P = 0.64). However, AAM improved ROSC on admission (AAM 141/673 (21.0%), non-AAM 77/673 (11.4%); OR 2.05; 95% CI, 1.51-2.78; P < 0.001). This tendency was consistent throughout our subgroup analysis categorized by body region of the severe injury (head trauma, torso trauma, and extremity/spine trauma). CONCLUSIONS: Prehospital AAM among EMS-witnessed traumatic OHCA patients was not associated with survival to discharge; however, ROSC on hospital admission improved for the AAM patients.

    DOI: 10.1002/ams2.786

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  • Hamman's Syndrome Accompanied by Diabetic Ketoacidosis; a Case Report. 国際誌

    Koya Yamashita, Takashi Hongo, Tsuyoshi Nojima, Tetsuya Yumoto, Atsunori Nakao, Hiromichi Naito

    Archives of academic emergency medicine   10 ( 1 )   e68   2022年

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    記述言語:英語  

    Hamman's syndrome is an uncommon clinical entity characterized by an idiopathic spontaneous pneumomediastinum as a result of a sudden increase in intra-alveolar pressure. It can be triggered by repeated vomiting or Kussmaul breathing associated with diabetic ketoacidosis (DKA). Careful attention to this particular condition is needed to avoid under-diagnosis and to provide optimal management. Herein, we report a case of an 18-year-old man complaining of chest discomfort and progressive weight loss, ultimately diagnosed with Hamman's syndrome secondary to DKA. The patient's symptoms disappeared after intravenous fluid and insulin administration, while his pneumomediastinum resolved following conservative treatment. Our report highlights the importance of recognition of the links between pneumomediastinum as a cause of chest pain in patients with DKA.

    DOI: 10.22037/aaem.v10i1.1709

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  • Luminal Administration of a Water-soluble Carbon Monoxide-releasing Molecule (CORM-3) Mitigates Ischemia/Reperfusion Injury in Rats Following Intestinal Transplantation. 国際誌

    Takafumi Obara, Hirotsugu Yamamoto, Toshiyuki Aokage, Takuro Igawa, Tsuyoshi Nojima, Takahiro Hirayama, Mizuki Seya, Michiko Ishikawa-Aoyama, Atsunori Nakao, Roberto Motterlini, Hiromichi Naito

    Transplantation   106 ( 7 )   1365 - 1375   2021年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND: The protective effects of carbon monoxide (CO) against ischemia/reperfusion (IR) injury during organ transplantation have been extensively investigated. Likewise, CO-releasing molecules (CORMs) are known to exert a variety of pharmacological activities via liberation of controlled amounts of CO in organs. Therefore, we hypothesized that intraluminal administration of water-soluble CORM-3 during cold storage of intestinal grafts would provide protective effects against IR injury. METHODS: Orthotopic syngeneic intestinal transplantation was performed in Lewis rats following 6 h of cold preservation in Ringer solution or University of Wisconsin solution. Saline containing CORM-3 (100 µmol/L) or its inactive counterpart (iCORM-3) was intraluminally introduced in the intestinal graft before cold preservation. RESULTS: Histopathological analysis of untreated and iCORM-3-treated grafts revealed a similar erosion and blunting of the intestinal villi. These changes in the mucosa structure were significantly attenuated by intraluminal administration of CORM-3. Intestinal mucosa damage caused by IR injury led to considerable deterioration of gut barrier function 3 h postreperfusion. CORM-3 significantly inhibited upregulation of proinflammatory mRNA levels, ameliorated intestinal morphological changes, and improved graft blood flow and mucosal barrier function. Additionally, CORM-3-treated grafts increased recipient survival rates. Pharmacological blockade of soluble guanylyl cyclase activity significantly reversed the protective effects conferred by CORM-3, indicating that CO partially mediates its therapeutic actions via soluble guanylyl cyclase activation. CONCLUSION: Our study demonstrates that luminally delivered CORM-3 provides beneficial effects in cold-stored rat small intestinal grafts and could be an attractive therapeutic application of CO in the clinical setting of organ preservation and transplantation.

    DOI: 10.1097/TP.0000000000004007

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  • The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020) 国際誌

    Moritoki Egi, Hiroshi Ogura, Tomoaki Yatabe, Kazuaki Atagi, Shigeaki Inoue, Toshiaki Iba, Yasuyuki Kakihana, Tatsuya Kawasaki, Shigeki Kushimoto, Yasuhiro Kuroda, Joji Kotani, Nobuaki Shime, Takumi Taniguchi, Ryosuke Tsuruta, Kent Doi, Matsuyuki Doi, Taka-aki Nakada, Masaki Nakane, Seitaro Fujishima, Naoto Hosokawa, Yoshiki Masuda, Asako Matsushima, Naoyuki Matsuda, Kazuma Yamakawa, Yoshitaka Hara, Masaaki Sakuraya, Shinichiro Ohshimo, Yoshitaka Aoki, Mai Inada, Yutaka Umemura, Yusuke Kawai, Yutaka Kondo, Hiroki Saito, Shunsuke Taito, Chikashi Takeda, Takero Terayama, Hideo Tohira, Hideki Hashimoto, Kei Hayashida, Toru Hifumi, Tomoya Hirose, Tatsuma Fukuda, Tomoko Fujii, Shinya Miura, Hideto Yasuda, Toshikazu Abe, Kohkichi Andoh, Yuki Iida, Tadashi Ishihara, Kentaro Ide, Kenta Ito, Yusuke Ito, Yu Inata, Akemi Utsunomiya, Takeshi Unoki, Koji Endo, Akira Ouchi, Masayuki Ozaki, Satoshi Ono, Morihiro Katsura, Atsushi Kawaguchi, Yusuke Kawamura, Daisuke Kudo, Kenji Kubo, Kiyoyasu Kurahashi, Hideaki Sakuramoto, Akira Shimoyama, Takeshi Suzuki, Shusuke Sekine, Motohiro Sekino, Nozomi Takahashi, Sei Takahashi, Hiroshi Takahashi, Takashi Tagami, Goro Tajima, Hiroomi Tatsumi, Masanori Tani, Asuka Tsuchiya, Yusuke Tsutsumi, Takaki Naito, Masaharu Nagae, Ichiro Nagasawa, Kensuke Nakamura, Tetsuro Nishimura, Shin Nunomiya, Yasuhiro Norisue, Satoru Hashimoto, Daisuke Hasegawa, Junji Hatakeyama, Naoki Hara, Naoki Higashibeppu, Nana Furushima, Hirotaka Furusono, Yujiro Matsuishi, Tasuku Matsuyama, Yusuke Minematsu, Ryoichi Miyashita, Yuji Miyatake, Megumi Moriyasu, Toru Yamada, Hiroyuki Yamada, Ryo Yamamoto, Takeshi Yoshida, Yuhei Yoshida, Jumpei Yoshimura, Ryuichi Yotsumoto, Hiroshi Yonekura, Takeshi Wada, Eizo Watanabe, Makoto Aoki, Hideki Asai, Takakuni Abe, Yutaka Igarashi, Naoya Iguchi, Masami Ishikawa, Go Ishimaru, Shutaro Isokawa, Ryuta Itakura, Hisashi Imahase, Haruki Imura, Takashi Irinoda, Kenji Uehara, Noritaka Ushio, Takeshi Umegaki, Yuko Egawa, Yuki Enomoto, Kohei Ota, Yoshifumi Ohchi, Takanori Ohno, Hiroyuki Ohbe, Kazuyuki Oka, Nobunaga Okada, Yohei Okada, Hiromu Okano, Jun Okamoto, Hiroshi Okuda, Takayuki Ogura, Yu Onodera, Yuhta Oyama, Motoshi Kainuma, Eisuke Kako, Masahiro Kashiura, Hiromi Kato, Akihiro Kanaya, Tadashi Kaneko, Keita Kanehata, Ken-ichi Kano, Hiroyuki Kawano, Kazuya Kikutani, Hitoshi Kikuchi, Takahiro Kido, Sho Kimura, Hiroyuki Koami, Daisuke Kobashi, Iwao Saiki, Masahito Sakai, Ayaka Sakamoto, Tetsuya Sato, Yasuhiro Shiga, Manabu Shimoto, Shinya Shimoyama, Tomohisa Shoko, Yoh Sugawara, Atsunori Sugita, Satoshi Suzuki, Yuji Suzuki, Tomohiro Suhara, Kenji Sonota, Shuhei Takauji, Kohei Takashima, Sho Takahashi, Yoko Takahashi, Jun Takeshita, Yuuki Tanaka, Akihito Tampo, Taichiro Tsunoyama, Kenichi Tetsuhara, Kentaro Tokunaga, Yoshihiro Tomioka, Kentaro Tomita, Naoki Tominaga, Mitsunobu Toyosaki, Yukitoshi Toyoda, Hiromichi Naito, Isao Nagata, Tadashi Nagato, Yoshimi Nakamura, Yuki Nakamori, Isao Nahara, Hiromu Naraba, Chihiro Narita, Norihiro Nishioka, Tomoya Nishimura, Kei Nishiyama, Tomohisa Nomura, Taiki Haga, Yoshihiro Hagiwara, Katsuhiko Hashimoto, Takeshi Hatachi, Toshiaki Hamasaki, Takuya Hayashi, Minoru Hayashi, Atsuki Hayamizu, Go Haraguchi, Yohei Hirano, Ryo Fujii, Motoki Fujita, Naoyuki Fujimura, Hiraku Funakoshi, Masahito Horiguchi, Jun Maki, Naohisa Masunaga, Yosuke Matsumura, Takuya Mayumi, Keisuke Minami, Yuya Miyazaki, Kazuyuki Miyamoto, Teppei Murata, Machi Yanai, Takao Yano, Kohei Yamada, Naoki Yamada, Tomonori Yamamoto, Shodai Yoshihiro, Hiroshi Tanaka, Osamu Nishida

    Journal of Intensive Care   9 ( 1 )   53 - 53   2021年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Springer Science and Business Media LLC  

    <title>Abstract</title>The Japanese Clinical Practice Guidelines for Management of Sepsis and Septic Shock 2020 (J-SSCG 2020), a Japanese-specific set of clinical practice guidelines for sepsis and septic shock created as revised from J-SSCG 2016 jointly by the Japanese Society of Intensive Care Medicine and the Japanese Association for Acute Medicine, was first released in September 2020 and published in February 2021. An English-language version of these guidelines was created based on the contents of the original Japanese-language version. The purpose of this guideline is to assist medical staff in making appropriate decisions to improve the prognosis of patients undergoing treatment for sepsis and septic shock. We aimed to provide high-quality guidelines that are easy to use and understand for specialists, general clinicians, and multidisciplinary medical professionals. J-SSCG 2016 took up new subjects that were not present in SSCG 2016 (e.g., ICU-acquired weakness [ICU-AW], post-intensive care syndrome [PICS], and body temperature management). The J-SSCG 2020 covered a total of 22 areas with four additional new areas (patient- and family-centered care, sepsis treatment system, neuro-intensive treatment, and stress ulcers). A total of 118 important clinical issues (clinical questions, CQs) were extracted regardless of the presence or absence of evidence. These CQs also include those that have been given particular focus within Japan. This is a large-scale guideline covering multiple fields; thus, in addition to the 25 committee members, we had the participation and support of a total of 226 members who are professionals (physicians, nurses, physiotherapists, clinical engineers, and pharmacists) and medical workers with a history of sepsis or critical illness. The GRADE method was adopted for making recommendations, and the modified Delphi method was used to determine recommendations by voting from all committee members.

    As a result, 79 GRADE-based recommendations, 5 Good Practice Statements (GPS), 18 expert consensuses, 27 answers to background questions (BQs), and summaries of definitions and diagnosis of sepsis were created as responses to 118 CQs. We also incorporated visual information for each CQ according to the time course of treatment, and we will also distribute this as an app. The J-SSCG 2020 is expected to be widely used as a useful bedside guideline in the field of sepsis treatment both in Japan and overseas involving multiple disciplines.

    DOI: 10.1186/s40560-021-00555-7

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    その他リンク: https://link.springer.com/article/10.1186/s40560-021-00555-7/fulltext.html

  • The effects of inhaling hydrogen gas on macrophage polarization, fibrosis, and lung function in mice with bleomycin-induced lung injury 査読

    Toshiyuki Aokage, Mizuki Seya, Takahiro Hirayama, Tsuyoshi Nojima, Masumi Iketani, Michiko Ishikawa, Yasuhiro Terasaki, Akihiko Taniguchi, Nobuaki Miyahara, Atsunori Nakao, Ikuroh Ohsawa, Hiromichi Naito

    BMC Pulmonary Medicine   21 ( 1 )   2021年12月

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    担当区分:最終著者, 責任著者   掲載種別:研究論文(学術雑誌)   出版者・発行元:Springer Science and Business Media LLC  

    <title>Abstract</title><sec>
    <title>Background</title>
    Acute respiratory distress syndrome, which is caused by acute lung injury, is a destructive respiratory disorder caused by a systemic inflammatory response. Persistent inflammation results in irreversible alveolar fibrosis. Because hydrogen gas possesses anti-inflammatory properties, we hypothesized that daily repeated inhalation of hydrogen gas could suppress persistent lung inflammation by inducing functional changes in macrophages, and consequently inhibit lung fibrosis during late-phase lung injury.


    </sec><sec>
    <title>Methods</title>
    To test this hypothesis, lung injury was induced in mice by intratracheal administration of bleomycin (1.0 mg/kg). Mice were exposed to control gas (air) or hydrogen (3.2% in air) for 6 h every day for 7 or 21 days. Respiratory physiology, tissue pathology, markers of inflammation, and macrophage phenotypes were examined.


    </sec><sec>
    <title>Results</title>
    Mice with bleomycin-induced lung injury that received daily hydrogen therapy for 21 days (BH group) exhibited higher static compliance (0.056 mL/cmH2O, 95% CI 0.047–0.064) than mice with bleomycin-induced lung injury exposed only to air (BA group; 0.042 mL/cmH2O, 95% CI 0.031–0.053, <italic>p</italic> = 0.02) and lower static elastance (BH 18.8 cmH2O/mL, [95% CI 15.4–22.2] vs. BA 26.7 cmH2O/mL [95% CI 19.6–33.8], <italic>p</italic> = 0.02). When the mRNA levels of pro-inflammatory cytokines were examined 7 days after bleomycin administration, interleukin (IL)-6, IL-4 and IL-13 were significantly lower in the BH group than in the BA group. There were significantly fewer M2-biased macrophages in the alveolar interstitium of the BH group than in the BA group (3.1% [95% CI 1.6–4.5%] vs. 1.1% [95% CI 0.3–1.8%], <italic>p</italic> = 0.008).


    </sec><sec>
    <title>Conclusions</title>
    The results suggest that hydrogen inhalation inhibits the deterioration of respiratory physiological function and alveolar fibrosis in this model of lung injury.


    </sec>

    DOI: 10.1186/s12890-021-01712-2

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  • The diagnosis of delayed expanding traumatic pseudoaneurysm of thoracic aorta caused by self-inflicted penetrating injury with crossbow bolt: A case report

    Shunsuke Nakamura, Taihei Yamada, Hiromichi Naito, Naoya Sakoda, Atsunori Nakao

    International Journal of Surgery Case Reports   88   106474 - 106474   2021年11月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier BV  

    DOI: 10.1016/j.ijscr.2021.106474

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  • A Rare Case of Pelvic Abscess Due to Spontaneous Non-traumatic Bladder Rupture 国際誌

    Kyosuke Inoguchi, Takashi Hongo, Hiromichi Naito, Atsunori Nakao

    Cureus   13 ( 10 )   e18913   2021年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Cureus, Inc.  

    Spontaneous bladder rupture is an uncommon and life-threatening urological emergency, and early diagnosis is often challenging. Herein, we report a case of intraperitoneal bladder rupture in an 81-year-old male with neurogenic bladder-the case of intraperitoneal bladder rupture required late laparotomy for pelvic abscess following initial conservative treatment. An eighty-one-year-old male presented to our emergency department with deterioration of consciousness, fever, and hematuria. He denied previous trauma history and had been treated for neurogenic bladder. Physical examination revealed signs of tenderness in the abdomen. A diagnosis of bladder rupture was made based on laboratory examination indicating renal failure and radiological imaging showing urinary ascites. Conservative management with a Foley catheter and antibiotics (meropenem administered 1 g/day) was initiated. On day seven after admission, the patient complained of abdominal pain and fever, and a diagnosis of pelvic abscess based on contrast-enhanced computed tomography and septic peritonitis was made. An emergency exploratory laparotomy for peritoneal drainage was performed. The postoperative course was uneventful, and the patient was discharged on day 29 after admission. Urinary bladder rupture should always be considered as a differential diagnosis in patients presenting with free fluid in the abdomen, peritonitis, reduced urine output, and hematuria. Clinicians should be aware that secondary bacterial peritonitis can occur as a major complication of a ruptured urinary bladder.

    DOI: 10.7759/cureus.18913

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  • Short or Irregular Sleep Duration in Early Childhood Increases Risk of Injury for Primary School-Age Children: A Nationwide Longitudinal Birth Cohort in Japan 査読 国際誌

    Takafumi Obara, Hiromichi Naito, Kohei Tsukahara, Naomi Matsumoto, Hirotsugu Yamamoto, Takashi Yorifuji, Atsunori Nakao

    International Journal of Environmental Research and Public Health   18 ( 18 )   9512 - 9512   2021年9月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:MDPI AG  

    The aim of this study was to investigate the longitudinal relationship between shorter or irregular sleep duration (SD) in early childhood and increased risk of injury at primary school age using data from a nationwide survey in Japan. We categorized SD into seven groups: 6 h, 7 h, 8 h, 9 hrs, 10 or 11 h, &gt;12 h, and irregular, based on questionnaire responses collected at 5.5 years old. The relationship between SD and incidence of injury at 5.5–nine years of age is shown. In addition, we completed a stratified analysis on children with or without problematic behavior at eight years old. We included 32,044 children, of which 6369 were classified as having an injury and 25,675 as not having an injury. Logistic regression model showed that shorter or irregular SD categories were associated with an increased adjusted odds ratio (aOR) for injuries (6 h: aOR 1.40, 95% confidence interval (CI) 1.19–1.66, 7 h: aOR 1.10, 95% CI, 0.98–1.23, 8 h: aOR 1.13, 95% CI, 1.02–1.26, irregular: aOR 1.26, 95% CI 1.10–1.43). The same tendency was observed with shorter or irregular SD in subgroups with or without behavioral problems. Shorter or irregular sleep habits during early childhood are associated with injury during primary school age.

    DOI: 10.3390/ijerph18189512

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  • Emergency Dispatches for Suicide Attempts During the COVID-19 Outbreak in Okayama, Japan: A Descriptive Epidemiological Study 査読

    Hiroshi Habu, Soshi Takao, Ryohei Fujimoto, Hiromichi Naito, Atsunori Nakao, Takashi Yorifuji

    Journal of Epidemiology   31 ( 9 )   511 - 517   2021年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Japan Epidemiological Association  

    BACKGROUND: Hardships associated with the ongoing coronavirus disease 2019 (COVID-19) pandemic can affect mental health, potentially leading to increased risk of suicide. We examined the relationship between the COVID-19 outbreak and suicide attempts in Okayama, Japan using information from emergency dispatches. METHODS: This was a descriptive epidemiological study. We collected information on emergency dispatches in Okayama City and Kibichuo from March to August in 2018, 2019, and 2020 (n = 47,770 cases). We compared emergency dispatches and their demographic characteristics, especially focusing on suicide attempts, during these 3 years. RESULTS: The number of emergency dispatches in 2020 decreased compared with the previous 2 years, while the number and proportion of emergency dispatches related to suicide attempts increased. This increase was more pronounced among women and those aged 25-49 years. Among women aged 25-49 years, there was a cumulative total of 43 suicide attempts in 2018 and 2019 and 73 suicide attempts in 2020. CONCLUSIONS: The number and proportion of emergency dispatches related to suicide attempts increased in 2020 compared with the previous 2 years, especially among women and those aged 25-49 years. This increase may be partly explained by hardships, such as economic losses or reduced social ties, during the COVID-19 outbreak.

    DOI: 10.2188/jea.je20210066

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  • Arrhythmogenic Right Ventricular Cardiomyopathy Diagnosed during Hospitalization for Cardiac Arrest.

    Masahiko Ochi, Atsuyoshi Iida, Yuka Takahashi, Masamichi Tanaka, Hironori Saito, Hiromichi Naito, Takeshi Mikane, Soichiro Fuke

    Acta medica Okayama   75 ( 4 )   517 - 521   2021年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a genetically mediated cardiomyopathy charac-terized by progressive myocardial loss of the right ventricle and its replacement by fibrofatty tissue, causing dyskinesia, aneurysm, and/or arrhythmia. The prevalence of ARVC is estimated to be 1 in 2,000-5,000, with the condition accounting for up to 20% of sudden cardiac deaths in individuals < 35 years old. This report describes the case of 61-year-old Japanese who was diagnosed with ARVC after cardiac arrest (CA) and successful resusci-tation. After the sudden CA, the restoration of spontaneous circulation was achieved with appropriate resusci-tation, followed by the introduction of target temperature management in the intensive care unit. He was diag-nosed with ARVC based on angiography and histology results. An ICD (implantable cardioverter-defibrillator) was implanted, and he was discharged without neurological sequelae 1 month post-CA. ARVC is an important cause of sudden CA, and successfully resuscitated patients with right ventricular dilation should undergo testing to rule out ARVC.

    DOI: 10.18926/AMO/62405

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  • Right Hemiplegia Following Acute Carbon Monoxide Poisoning 国際誌

    Kenji Aoshima, Hidenaru Yamaoka, Shunsuke Nakamura, Tsuyoshi Nojima, Hiromichi Naito, Atsunori Nakao

    Cureus   13 ( 7 )   e16738   2021年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Cureus, Inc.  

    Acute carbon monoxide (CO) poisoning remains a common cause of poison-related death and influences neurological function. An 83-year-old female was transferred to our emergency unit due to hypertension with dizziness, headache, and right hemiplegia. There was no radiographic evidence of ischemic stroke. The family members reported that the patient may have been exposed to CO by briquettes burned inside a closed room. High flow oxygen therapy was given for suspected CO intoxication and her symptoms quickly improved. Although we do not have clear evidence, we presume that hemiplegia in our patient was caused by CO intoxication, based on rapid recovery with oxygen therapy, carboxyhemoglobin (COHb) level elevation (3.0%), polycythemia, and neuroimaging. Despite the hematogenous effects of CO, paralysis appeared to be more severe on her right side than on her left side. MRI and blood tests helped to support CO as the suspected cause of her hemiplegia. This case reconfirms the importance of medical interviewing by medical practitioners, even in an emergency setting.

    DOI: 10.7759/cureus.16738

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  • Unrecognized Orbital Images Cause Diagnostic Confusion: Silicone Oil and Implanted Silicone Encircling Bands 国際誌

    Tsuyoshi Nojima, Takafumi Obara, Kohei Tsukahara, Atsunori Nakao, Hiromichi Naito

    Case Reports in Emergency Medicine   2021   1 - 3   2021年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Hindawi Limited  

    Introduction. Most physicians are not familiar with postoperative changes to the orbit, so radiologists and clinicians may sometimes find it challenging to conduct a proper radiological assessment of the globe of the eye and orbital abnormalities. We present a patient with head trauma who had surgery for retinal detachment with implantation of silicone encircling bands. This case report may help clinicians recognize imaging characteristics after ophthalmic surgery to prevent misdiagnosis and unnecessary workup. Case Report. An 18-year-old man with severe head trauma was admitted to our hospital. Initial computed tomography (CT) revealed a high attenuation of intraocular silicone that could be mistaken for a hemorrhage. Ophthalmological examination and detailed ophthalmic history confirmed silicone oil in his eye for treatment of retinal detachment. Knowledge of the anatomical changes and radiological appearance of postsurgical findings following retinal detachment, including the surgical materials of silicone oil or bands, can prevent unnecessary alarm. Conclusion. Implanted ophthalmic devices, for example, silicone oil, appear similar to hemorrhages on CT and magnetic resonance imaging and cause diagnostic confusion. When in doubt, it is useful to assess the clinical presentation and obtain an accurate medical history.

    DOI: 10.1155/2021/9940395

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    その他リンク: http://downloads.hindawi.com/journals/criem/2021/9940395.xml

  • Carbon monoxide poisoning during pregnancy treated with hyperbaric oxygen 国際誌

    Yoshinori Kosaki, Hiroki Maeyama, Tsuyoshi Nojima, Takafumi Obara, Atsunori Nakao, Hiromichi Naito

    Clinical Case Reports   9 ( 5 )   e04138   2021年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    Acute carbon monoxide (CO) intoxication during pregnancy causes fetal death and teratogenic effects. Hyperbaric oxygen (HBO2) therapy has the potential to improve them. HBO2 therapy should be considered to treat CO intoxication during pregnancy.

    DOI: 10.1002/ccr3.4138

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    その他リンク: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/ccr3.4138

  • Characteristics of self-inflicted injury among suicidal patients: analysis of nation-wide trauma registry 査読

    Takeshi Nishimura, Hiromichi Naito, Atsunori Nakao, Shinichi Nakayama

    Trauma Surgery & Acute Care Open   6 ( 1 )   e000694 - e000694   2021年4月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:BMJ  

    <sec><title>Purpose</title>Self-inflicted injury is one of the most common causes of suicide. Extremity injury is thought to occur most frequently among penetrating injury; however, epidemiology among patients attempting suicide is unknown. This study aims to find the characteristics of penetrating self-inflicted trauma patients.

    </sec><sec><title>Methods</title>This is a retrospective cohort study of Japanese nation-wide trauma registry (the Japan National Trauma Data Bank) between January 1, 2004 and December 31, 2017. Patients who attempted suicide with penetrating injury were eligible. We evaluated the occurrence of injury based on injury site (neck/face, chest, abdomen, extremity) as a dependent variable and aging as an independent variable using a generalized linear model and compare those groups with spline models.

    </sec><sec><title>Results</title>4576 trauma patients were eligible. Excluding patients with missing age, missing survival data, and missing abbreviate injury score, 4183 patients were enrolled in this study. Common injury site is follows: abdomen 1772 patients (42.4%), extremity 1344 patients (32.0%), neck/face 1253 patients (30.0%), and chest 993 patients (23.7%). The occurrence of neck/face injury, chest injury, and abdominal injury increased with age. On contrary, the rate of extremity injury decreased with age.

    </sec><sec><title>Conclusions</title>Among self-inflicted trauma patients, abdominal injury was the most common injury, and neck/face injury, chest injury, and abdominal injury were related with aging. On the contrary, the rate of extremity injury decreased as patients’ age progressed.

    </sec><sec><title>Level of evidence</title>Retrospective cohort study, Level III.

    </sec>

    DOI: 10.1136/tsaco-2021-000694

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  • Takotsubo Cardiomyopathy Caused by Carbon Dioxide Intoxication 国際誌

    Haruna Inoue, Takeshi Nishimura, Tsuyoshi Nojima, Hiromichi Naito

    Cureus   13 ( 3 )   e14179   2021年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Cureus, Inc.  

    A 49-year-old man transferred to our hospital for dyspnea that developed while transporting significant loads of dry ice, which may have caused potential carbon dioxide intoxication. On admission, he presented hyperventilation and disorientation. Transthoracic echocardiography showed the reduced motion of the anterior wall of the left ventricle with decreased left ventricular ejection fraction. The patient underwent coronary angiography, which did not show apparent coronary arterial stenosis. The electrocardiogram revealed T-wave change and echocardiography results showed the subsided changes on the third hospital day. He was discharged without any symptoms on the fourth hospital day. Our case demonstrates the potential association between carbon dioxide intoxication and Takotsubo cardiomyopathy. Our experience may inform emergency physicians in formulating diagnostic/therapeutic approaches for similar patients experiencing cardiac failure following carbon dioxide intoxication.

    DOI: 10.7759/cureus.14179

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  • Prevalence and predictors of direct discharge home following hospitalization of patients with serious adverse events managed by the rapid response system in Japan: a multicenter, retrospective, observational study 査読 国際誌

    Takashi Hongo, Hiromichi Naito, Toshifumi Fujiwara, Takaki Naito, Yosuke Homma, Yoshihisa Fujimoto, Morooka Takaya, Yuji Yamamori, Taka‐aki Nakada, Tsuyoshi Nojima, Atsunori Nakao, Shigeki Fujitani, Shinsuke Fujiwara, Masayasu Arai, Eiji Kawamoto, Yoshiki Sento, Yuta Kawase, Kazuma Nagata, Takuro Saito, Masahiro Tamashiro, Kazuhiro Aoki, Atsushi Miyawaki, Tomoyuki Masuyama, Tatsuya Kawasaki, Takuya Kawaguchi, Takahiro Atsumi, Tomoyuki Ikeda, Yoshiro Hayashi, Takanao Otake, Masaru Tobe, Ryosuke Sekine, Takaaki Nakada, Kazuhiko Sugimoto, Hiroshi Onozawa, Kentaro Miyake, Chikaaki Nakamichi, Naraba Hiromu, Jun Makino, Kenzo Ishii, Yasunobu Goto, Hitoshi Kikuchi, Tadaaki Takada, Dai Taguchi, Kenzo Ishii, Eisei Hoshiyama, Hiromichi Miyabe, Masaru Okamoto, Masahiro Koide, Yoichi Kase, Takuya Hashino, Takehiro Niitsu, Hiroshi Kamijo

    Acute Medicine & Surgery   8 ( 1 )   e690   2021年1月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    AIM: The rapid response system (RRS) is an in-hospital medical safety system. To date, not much is known about patient disposition after RRS activation, especially discharge home. This study aimed to investigate the prevalence, characteristics, and outcomes of patients with adverse events who required RRS activation. METHODS: Retrospective data from the In-Hospital Emergency Registry in Japan collected from April 2016 to November 2020 were eligible for our analysis. We divided patients into Home Discharge, Transfer, and Death groups. The primary outcome was the prevalence of direct discharge home, and independently associated factors were determined using multivariable logistic regression. RESULTS: We enrolled 2,043 patients who met the inclusion criteria. The prevalence of discharge home was 45.7%; 934 patients were included in the Home Discharge group. Age (adjusted odds ratio [AOR] 0.96; 95% confidence interval [CI], 0.95-0.97), malignancy (AOR 0.69; 95% CI, 0.48-0.99), oxygen administration before RRS (AOR 0.49; 95% CI, 0.36-0.66), cerebral performance category score on admission (AOR 0.38; 95% CI, 0.26-0.56), do not attempt resuscitation order before RRS (AOR 0.17; 95% CI, 0.10-0.29), RRS call for respiratory failure (AOR 0.50; 95% CI, 0.34-0.72), RRS call for stroke (AOR 0.12; 95% CI, 0.03-0.37), and intubation (AOR 0.20; 95% CI, 0.12-0.34) were independently negative, and RRS call for anaphylaxis (AOR 15.3; 95% CI, 2.72-86.3) was positively associated with discharge home. CONCLUSION: Less than half of the in-hospital patients under RRS activation could discharge home. Patients' conditions before RRS activation, disorders requiring RRS activation, and intubation were factors that affected direct discharge home.

    DOI: 10.1002/ams2.690

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  • Refractory gastric ulcer due to undisclosed use of topical diclofenac epolamine patches 査読 国際誌

    Yuta Oda, Hiromichi Naito, Tsuyoshi Nojima, Atsunori Nakao

    Acute Medicine & Surgery   8 ( 1 )   e710   2021年1月

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    担当区分:責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    BACKGROUND: Topical forms of nonsteroidal anti-inflammatory drugs (NSAIDs) have been created to lessen systemic adverse effects. In general, they are believed to be well tolerated and appropriate for use as an over-the-counter (OTC) drug. CASE PRESENTATION: A 68-year-old woman visited our clinic due to tarry stool. The patient reported multiple episodes of recurrent bleeding from a gastric ulcer for 2 months and was treated with endoscopic hemostatic clipping. The patient disclosed she had been using a large number of diclofenac patches for more than 3 months. The patient was treated conservatively by discontinuation of diclofenac patches and treatment with a proton pump inhibitor and omeprazole. CONCLUSION: In conclusion, inappropriate use of topical NSAID patches can be a cause of peptic ulcer bleeding. Patients reporting multiple episodes of recurrent bleeding from a gastric ulcer should be questioned, particularly about the use of OTC medications that might include topical NSAID patches.

    DOI: 10.1002/ams2.710

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  • State‐of‐the‐art methods for the treatment of severe hemorrhagic trauma: selective aortic arch perfusion and emergency preservation and resuscitation—what is next? 国際誌

    Atsuyoshi Iida, Hiromichi Naito, Tsuyoshi Nojima, Tetsuya Yumoto, Taihei Yamada, Noritomo Fujisaki, Atsunori Nakao, Takeshi Mikane

    Acute Medicine & Surgery   8 ( 1 )   e641   2021年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    Trauma is a primary cause of death globally, with non-compressible torso hemorrhage constituting an important part of "potentially survivable trauma death." Resuscitative endovascular balloon occlusion of the aorta has become a popular alternative to aortic cross-clamping under emergent thoracotomy for non-compressible torso hemorrhage in recent years, however, it alone does not improve the survival rate of patients with severe shock or traumatic cardiac arrest from non-compressible torso hemorrhage. Development of novel advanced maneuvers is essential to improve these patients' survival, and research on promising methods such as selective aortic arch perfusion and emergency preservation and resuscitation is ongoing. This review aimed to provide physicians in charge of severe trauma cases with a broad understanding of these novel therapeutic approaches to manage patients with severe hemorrhagic trauma, which may allow them to develop lifesaving strategies for exsanguinating trauma patients. Although there are still hurdles to overcome before their clinical application, promising research on these novel strategies is in progress, and ongoing development of synthetic red blood cells and techniques that reduce ischemia-reperfusion injury may further maximize their effects. Both continuous proof-of-concept studies and translational clinical evaluations are necessary to clinically apply these hemostasis approaches to trauma patients.

    DOI: 10.1002/ams2.641

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  • Variability of extracorporeal cardiopulmonary resuscitation practice in patients with out‐of‐hospital cardiac arrest from the emergency department to intensive care unit in Japan

    Toru Hifumi, Akihiko Inoue, Toru Takiguchi, Kazuhiro Watanabe, Takayuki Ogura, Tomoya Okazaki, Shinichi Ijuin, Ryosuke Zushi, Hideki Arimoto, Hiroaki Takada, Shinichirou Shiraishi, Yuko Egawa, Jun Kanda, Michitaka Nasu, Makoto Kobayashi, Masaaki Sakuraya, Hiromichi Naito, Shunichiro Nakao, Norio Otani, Ichiro Takeuchi, Naofumi Bunya, Takafumi Shimizu, Hirotaka Sawano, Wataru Takayama, Shigeki Kushimoto, Tomohisa Shoko, Makoto Aoki, Takayuki Otani, Yoshinori Matsuoka, Koichiro Homma, Kunihiko Maekawa, Yoshio Tahara, Reo Fukuda, Migaku Kikuchi, Takuo Nakagami, Yoshihiro Hagiwara, Nobuya Kitamura, Kazuhiro Sugiyama, Tetsuya Sakamoto, Yasuhiro Kuroda

    Acute Medicine & Surgery   8 ( 1 )   2021年1月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    DOI: 10.1002/ams2.647

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  • Incidence and characteristics of medical emergencies related to dental treatment: a retrospective single‐center study 査読 国際誌

    Kyoichi Obata, Hiromichi Naito, Hiromasa Yakushiji, Takafumi Obara, Kisho Ono, Tsuyoshi Nojima, Kohei Tsukahara, Taihei Yamada, Akira Sasaki, Atsunori Nakao

    Acute Medicine & Surgery   8 ( 1 )   e651   2021年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    AIM: Although uncommon, medical emergencies arise in general dental practice. Inadequate data on their severity and frequency makes targeting medical education for general dental practitioners difficult. This also makes planning for unexpected events challenging for practitioners and makes collaborating with emergency physicians burdensome. We aimed to clarify the incidence and characteristics of a dental outpatient department's medical emergencies. METHODS: This single-center, retrospective, observational study was undertaken with patients who visited the dental outpatient department of Okayama University Hospital during the 8-year period. The primary outcome of the study was to identify the incidence and characteristics of medical emergencies in the dental outpatient department. Then we examined the timing of medical emergencies, administered medications, and final disposition (home/admission). RESULTS: During the period, 1,146,929 patients were enrolled. Forty-two patients (0.0037%) were consulted as medical emergencies. More than 60% of the incidents were vasovagal syncope, and dehydration and hypoglycemia were the second most prevalent at 9.5%. The most common types of dental treatments were tooth extraction (45.2%), followed by general dental treatment (28.6%), and other dental surgery such as implant placement (14.3%). Types of medical emergencies occurred equally before, during, and after dental treatment. Antihypertensive agents, sedatives, or glucose were used. For patients with emergencies, 90.5% recovered during the day and returned home, and 9.5% were hospitalized. CONCLUSION: The incidence of medical emergencies was low in our dental outpatient department. Knowledge of basic management principles, regular education for emergency care, and practicing first aid skills are mandatory for safe patient management.

    DOI: 10.1002/ams2.651

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  • Cardiac arrest due to liquid nicotine intoxication: a case report

    Atsuyoshi Iida, Yuki Fujiwara, Tsuyoshi Nojima, Hiromichi Naito, Atsunori Nakao, Takeshi Mikane

    Acute Medicine &amp; Surgery   8 ( 1 )   2021年1月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    DOI: 10.1002/ams2.720

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  • Plastic Bronchitis in a Five-Year-Old Boy Treated Using Extracorporeal Membrane Oxygenation; a Case Report. 国際誌

    Tsuyoshi Nojima, Hiromichi Naito, Takafumi Obara, Kohei Tsukahara, Atsunori Nakao

    Archives of academic emergency medicine   9 ( 1 )   e16   2021年

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    記述言語:英語  

    Plastic bronchitis is an uncommon disorder marked by the production of bronchial casts and acute respiratory failure development. In pediatric cases, influenza infection sometimes results in the obstruction of bronchi and leads to this potentially life-threatening condition. We report the case of a five-year-old boy with plastic bronchitis related to influenza A infection, which could only be recovered by the use of extracorporeal membrane oxygenation (ECMO). ECMO could effectively provide sufficient oxygenation for patients suffering from severe reversible acute respiratory failure. If patients infected with the influenza virus present acute respiratory distress with total lung atelectasis, clinicians should consider the diagnosis of plastic bronchitis and the subsequent treatment interventions with ECMO in a severe cases.

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  • Three-year-old traumatic liver injury patient treated successfully using transcatheter arterial embolization 国際誌

    Atsuyoshi Iida, Tsuyoshi Ryuko, Masaichi Kemmotsu, Hiroaki Ishii, Hiromichi Naito, Atsunori Nakao

    International Journal of Surgery Case Reports   70   205 - 208   2020年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier BV  

    INTRODUCTION: Liver injury is the most vulnerable to blunt abdominal trauma. Diagnostic evaluation and treatment of blunt liver trauma in children have changed essentially over the last decades. PRESENTATION OF CASE: A 3-year-old girl, weighing 10 kg was run over by a car and admitted to our hospital. Due to the liver injury and increased intra-abdominal hemorrhage confirmed by computed tomography, emergent transcatheter arterial embolization (TAE) was performed. Hemostasis was successfully obtained without complications. The patient had a good postoperative course and was discharged on the 9th day after admission. DISCUSSION: To the best of our knowledge, this case is the youngest and lowest weight emergency TAE success cases of childhood liver injury. TAE is an alternative to laparotomy and a useful procedure to accomplish nonsurgical management in adult who are hemodynamically stable and have no other associated injury requiring laparotomy. On the other hand, TAE is considered to have some complications in child cases because of the small diameter of the artery and the tendency to spasm. Our case showed that TAE can be a safe option for emergency hemostasis in pediatric trauma cases weighing 10 kg. CONCLUSION: Emergency physicians must be aware that radiological intervention is an important adjunct to management of childhood liver injury.

    DOI: 10.1016/j.ijscr.2020.04.036

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  • Pediatric airway compromise due to thyroid storm associated with influenza A infection: A case report 国際誌

    Taiki Higaki, Kohei Tsukahara, Takafumi Obara, Tsuyoshi Nojima, Hirotsugu Yamamoto, Takaaki Osako, Hiromichi Naito, Atsunori Nakao

    Respiratory Medicine Case Reports   31   101182 - 101182   2020年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier BV  

    Thyroid storm is a potentially fatal intensification of thyrotoxicosis normally marked by tachycardia, hyperthermia, impaired mental status, and severe agitation. It can be initiated by numerous causes. Failure to promptly diagnose the condition may lead to high mortality. Early diagnosis and treatment of thyroid storm are essential to prevent further life-threatening complications. A 10-year-old girl was admitted to our emergency center for intensive care. The patient presented tachypnea with stridor, paradoxical abdominal breathing, and "barking" cough. The patient was diagnosed as upper airway obstruction complicated by thyroid storm associated with influenza infection. Following immediate airway management, the patient was administered a short-acting beta-blocker, hydrocortisone, thiamazole, and saturated solution of potassium iodide was initiated. The patient was extubated on day 8 and transferred to a local hospital on day 11 without adverse complications. When examining patients with influenza infection, emergency doctors should be more attentive not to miss other critical diagnoses. The present case was initially diagnosed as croup due to influenza infection. Sharing our experience may help emergency physicians treat similar cases of pediatric airway compromise due to thyroid storm.

    DOI: 10.1016/j.rmcr.2020.101182

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  • Factors Affecting the Absorption of Midazolam to the Extracorporeal Membrane Oxygenation Circuit. 査読

    Atsuyoshi Iida, Hiromichi Naito, Takashi Yorifuji, Yoshito Zamami, Akane Yamada, Tadashi Koga, Toru Imai, Toshiaki Sendo, Atsunori Nakao, Shingo Ichiba

    Acta medica Okayama   73 ( 2 )   101 - 107   2019年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Sedatives are administered during extracorporeal membrane oxygenation (ECMO) therapy to ensure patient safety, reduce the metabolic rate and correct the oxygen supply-demand balance. However, the concentrations of sedatives can be decreased due to absorption into the circuit. This study examined factors affecting the absorption of a commonly used sedative, midazolam (MDZ). Using multiple ex vivo simulation models, three factors that may influence MDZ levels in the ECMO circuit were examined: polyvinyl chloride (PVC) tubing in the circuit, use of a membrane oxygenator in the circuit, and heparin coating of the circuit. We also assessed changes in drug concentration when MDZ was re-injected in a circuit. The MDZ level decreased to approximately 60% of the initial concentration in simulated circuits within the first 30 minutes. The strongest factor in this phenomenon was contact with the PVC tubing. Membrane oxygenator use tended to increase MDZ loss, whereas heparin circuit coating had no influence on MDZ absorption. Similar results were obtained when a second dose of MDZ was injected to the second-use circuits.

    DOI: 10.18926/AMO/56645

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  • Gastric Emphysema in a Critically Ill Patient Successfully Treated without Surgery 国際誌

    Hiromi Ihoriya, Tetsuya Yumoto, Masaya Iwamuro, Noritomo Fujisaki, Takaaki Osako, Hiromichi Naito, Atsunori Nakao

    Case Reports in Critical Care   2019   1 - 4   2019年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Hindawi Limited  

    Gastric emphysema is a relatively rare clinical entity caused by injury to the gastric mucosa. A 62-year-old Japanese male with a history of heavy alcohol consumption and smoking was admitted to the emergency intensive care unit due to severe hypercapnic respiratory acidosis. His body mass index was only 12.6. Ten days after initiation of enteral feeding, he complained of abdominal pain. Computed tomography revealed intraluminal air in the distended gastric wall. Esophagogastroduodenoscopy showed diffuse edema, redness, and erosion throughout the stomach. Based on the findings of narrow angle and short distance of the aorta-superior mesenteric artery, the patient was diagnosed with gastric emphysema associated with superior mesenteric artery syndrome. He was successfully managed nonoperatively with treatments including intravenous antibiotics, gastric decompression, and bowel rest. Physicians should be aware of this unusual condition in such critically ill patients complaining of abdominal pain and needing close monitoring and observation to exclude gastric necrosis or perforation.

    DOI: 10.1155/2019/1824101

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    その他リンク: http://downloads.hindawi.com/journals/cricc/2019/1824101.xml

  • 初療時には診断をつけられなかった農薬中毒の2例

    有吉 雪乃, 内藤 宏道, 竹居 セラ, 森本 直樹, 三浦 雅布, 中尾 篤典, 宮石 智

    中毒研究   32 ( 1 )   100 - 100   2019年3月

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    記述言語:日本語   出版者・発行元:(株)へるす出版  

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  • Impact of contrast extravasation on computed tomography of the psoas major muscle in patients with blunt torso trauma 査読 国際誌

    Tetsuya Yumoto, Hiromichi Naito, Takao Hiraki, Yasuaki Yamakawa, Taihei Yamada, Atsunori Nakao

    Journal of Trauma and Acute Care Surgery   86 ( 2 )   268 - 273   2019年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Ovid Technologies (Wolters Kluwer Health)  

    BACKGROUND: The clinical significance of contrast extravasation (CE) on computed tomography (CT) of the psoas major muscle after blunt torso trauma and the optimal management of patients requiring transcatheter arterial embolization (TAE) of the lumbar artery have not been well elucidated. The aim of this study was to investigate the impact of CE on CT to determine the need for TAE of the lumbar artery. METHODS: We examined a single-center retrospective cohort of blunt torso trauma patients who underwent contrast-enhanced CT from 2008 to 2017. Basic demographics and clinical data were obtained, including the number of lumbar transverse process fractures (LTPFs) and maximum psoas major muscle hematoma (PMMH) size and ratio. Maximum PMMH size was analyzed by measuring the cross-sectional area of hematoma size at the level of CE. Psoas major muscle hematoma size ratio was obtained by dividing maximum PMMH size by psoas major muscle size of the unaffected side at the same slice level. RESULTS: A total of 762 patients were included. One hundred seventeen patients had LTPFs and/or PMMH. Of 117 patients, 25 had CE on CT of the psoas major muscle and had significantly higher rates of older age and severe injury compared with those without CE. Of the 25 patients with CE, 13 required TAE of the lumbar artery. Patients who required TAE had a significantly higher number of LTPFs (4 vs. 2, p = 0.011) and higher PMMH size ratio (2.10 vs. 1.32, p = 0.016). Psoas major muscle hematoma size ratio revealed moderate accuracy (area under the receiver operating characteristic curve, 0.782). CONCLUSIONS: Approximately half of the blunt torso trauma patients with CE on CT of the psoas major muscle will require TAE of the lumbar artery. Higher number of LTPFs and larger PMMH size can be a predictor of the need for TAE of the lumbar artery among patients with CE on CT. LEVEL OF EVIDENCE: Therapeutic/care management, level IV.

    DOI: 10.1097/ta.0000000000002121

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  • Mortality in trauma patients admitted during, before, and after national academic emergency medicine and trauma surgery meeting dates in Japan 査読 国際誌

    Tetsuya Yumoto, Hiromichi Naito, Hiromi Ihoriya, Takashi Yorifuji, Atsunori Nakao

    PLOS ONE   14 ( 1 )   e0207049 - e0207049   2019年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Public Library of Science (PLoS)  

    Annually, many physicians attend national academic meetings. While participating in these meetings can have a positive impact on daily medical practice, attendance may result in reduced medical staffing during the meeting dates. We sought to examine whether there were differences in mortality after trauma among patients admitted to the hospital during, before, and after meeting dates. Using the Japan Trauma Data Bank, we analyzed in-hospital mortality in patients with traumatic injury admitted to the hospital from 2004 to 2015 during the dates of two national academic meetings-the Japanese Association for Acute Medicine (JAAM) and the Japanese Association for the Surgery of Trauma (JAST). We compared the data with that of patients admitted with trauma during identical weekdays in the weeks before and after the meetings, respectively. We used multiple logistic regression analysis to compare outcomes among the three groups. A total of 7,491 patients were included in our analyses, with 2,481, 2,492, and 2,518 patients in the during, before, and after meeting dates groups, respectively; their mortality rates were 7.3%, 8.0%, and 8.5%, respectively. After adjusting for covariates, no significant differences in in-hospital mortality were found among the three groups (adjusted odds ratio [95% CI] of the before meeting dates and after meeting dates groups; 1.18 [0.89-1.56] and 1.23 [0.93-1.63], respectively, with the during meeting dates group as the reference category). No significant differences in in-hospital mortality were found among trauma patients admitted during, before, and after the JAAM and JAST meeting dates.

    DOI: 10.1371/journal.pone.0207049

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  • Heat-not-burn cigarettes induce fulminant acute eosinophilic pneumonia requiring extracorporeal membrane oxygenation. 査読 国際誌

    Aokage T, Tsukahara K, Fukuda Y, Tokioka F, Taniguchi A, Naito H, Nakao A

    Respiratory medicine case reports   26   87 - 90   2019年

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  • 右内頸静脈穿刺による脱血での体外膜型肺を併用した心肺蘇生 脱血カニューレに関して

    内藤 宏道, 平山 隆浩, 塚原 紘平

    日本集中治療医学会雑誌   25 ( 6 )   467 - 468   2018年11月

  • Emphysematous cystitis successfully treated with hyperbaric oxygen therapy: case report

    Hirotaka Yasuhara, Hiromichi Naito, Yoshinori Kosaki, Yasuaki Yamakawa, Atsuyoshi Iida, Tetsuya Yumoto, Hirotsugu Yamamoto, Taihei Yamada, Kohei Tsukahara, Takaaki Osako, Yasuhiro Mandai, Atsunori Nakao

    UNDERSEA AND HYPERBARIC MEDICINE   45 ( 6 )   701 - 703   2018年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:UNDERSEA & HYPERBARIC MEDICAL SOC INC  

    Emphysematous cystitis is an uncommon acute infection of the underlying bladder musculature and mucosa, caused by gas-producing organisms. Here we describe an 87-year-old woman with diabetes mellitus and emphysematous cystitis who was successfully treated with hyperbaric oxygen (HBO2) therapy. Her predisposition of diabetes and infection with gas-producing bacteria was considered to precede the development of emphysematous cystitis. Computed tomography revealed gas accumulation in the bladder wall and lumen. Antibiotics and HBO2 therapy were administered. HBO2 therapy may be beneficial due to the improvement in oxygenation of the tissues affected by the disease. HBO2 is a useful adjunct therapy for the management of severe emphysematous cystitis.

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  • 【ぜひ知っておきたい水・電解質異常と輸液管理】各種病態における輸液管理 薬物中毒

    小崎 吉訓, 内藤 宏道, 中尾 篤典

    臨牀と研究   95 ( 8 )   871 - 875   2018年8月

  • Cushing’s sign and severe traumatic brain injury in children after blunt trauma: a nationwide retrospective cohort study in Japan 査読

    Tetsuya Yumoto, Hiromichi Naito, Takashi Yorifuji, Hiroki Maeyama, Yoshinori Kosaki, Hirotsugu Yamamoto, Kohei Tsukahara, Takaaki Osako, Atsunori Nakao

    BMJ Open   8 ( 3 )   e020781 - e020781   2018年3月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:BMJ  

    <sec><title>Objective</title>We tested whether Cushing’s sign could predict severe traumatic brain injury (TBI) requiring immediate neurosurgical intervention (BI-NSI) in children after blunt trauma.

    </sec><sec><title>Design</title>Retrospective cohort study using Japan Trauma Data Bank.

    </sec><sec><title>Setting</title>Emergency and critical care centres in secondary and tertiary hospitals in Japan.

    </sec><sec><title>Participants</title>Children between the ages of 2 and 15 years with Glasgow Coma Scale motor scores of 5 or less at presentation after blunt trauma from 2004 to 2015 were included. A total of 1480 paediatric patients were analysed.

    </sec><sec><title>Primary outcome measures</title>Patients requiring neurosurgical intervention within 24 hours of hospital arrival and patients who died due to isolated severe TBI were defined as BI-NSI. The combination of systolic blood pressure (SBP) and heart rate (HR) on arrival, which were respectively divided into tertiles, and its correlation with BI-NSI were investigated using a multiple logistic regression model.

    </sec><sec><title>Results</title>In the study cohort, 297 (20.1%) exhibited BI-NSI. After adjusting for sex, age category and with or without haemorrhage shock, groups with higher SBP and lower HR (SBP ≥135 mm Hg; HR ≤92 bpm) were significantly associated with BI-NSI (OR 2.84, 95% CI 1.68 to 4.80, P&lt;0.001) compared with the patients with normal vital signs. In age-specific analysis, hypertension and bradycardia were significantly associated with BI-NSI in a group of 7–10 and 11–15 years of age; however, no significant association was observed in a group of 2–6 years of age.

    </sec><sec><title>Conclusions</title>Cushing’s sign after blunt trauma was significantly associated with BI-NSI in school-age children and young adolescents.

    </sec>

    DOI: 10.1136/bmjopen-2017-020781

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  • Staphylococcus aureus Bacteremia Complicated by Psoas Abscess and Infective Endocarditis in a Patient with Atopic Dermatitis. 査読

    Tsuboi I, Yumoto T, Toyokawa T, Matsueda K, Horii J, Naito H, Nakao A.

    Case Rep Infect Dis   2017   2017年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Indirect Calorimetry Measurement of Energy Expenditure Related to Body Position Changes in Healthy Adults. 査読

    Obata K, Yumoto T, Fuke S, Tsukahara K, Naito H, Iida A, Takahashi T, Ujike Y, Nakao A.

    Acta Med Okayama   71 ( 6 )   467 - 473   2017年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.18926/AMO/55583

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  • Pneumatosis cystoides intestinalis presenting as pneumoperitoneum in a patient with chronic obstructive pulmonary disease 査読

    Atsuyoshi Iida*,Hiromichi Naito*,Kohei Tsukahara*,Tetsuya Yumoto*,Nobuyuki Nosaka*,Shinnichi Kawana,Keiji Sato*,Nobuhiro Takeuchi,Jyunichi Soneda,Atsunori Nakao*

    Journal of Medical Case Reports   11 ( 1 )   1 - 10   2017年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1186/s13256-017-1198-2

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  • Venous thromboembolism in major trauma patients: a single-center retrospective cohort study of the epidemiology and utility of D-dimer for screening. 査読 国際誌

    Yumoto T, Naito H, Yamakawa Y, Iida A, Tsukahara K, Nakao A.

    Acute Med Surg   4 ( 4 )   394 - 400   2017年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1002/ams2.290

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  • Occult Sources of Bleeding in Blunt Trauma : A Narrative Review.

    Tetsuya Yumoto, Yoshinori Kosaki, Yasuaki Yamakawa, Atsuyoshi Iida, Hirotsugu Yamamoto, Taihei Yamada, Kohei Tsukahara, Hiromichi Naito, Takaaki Osako, Atsunori Nakao

    Acta medica Okayama   71 ( 5 )   363 - 368   2017年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Worldwide, hemorrhagic shock in major trauma remains a major potentially preventable cause of death. Controlling bleeding and subsequent coagulopathy is a big challenge. Immediate assessment of unidentified bleeding sources is essential in blunt trauma patients with hemorrhagic shock. Chest/pelvic X-ray in conjunction with ultrasonography have been established classically as initial diagnostic imaging modalities to identify the major sources of internal bleeding including intra-thoracic, intra-abdominal, or retroperitoneal hemorrhage related to pelvic fracture. Massive soft tissue injury, regardless of whether isolated or associated with multiple injuries, occasionally causes extensive hemorrhage and acute traumatic coagulopathy. Specific types of injuries, including soft tissue injury or retroperitoneal hemorrhage unrelated to pelvic fracture, can potentially be overlooked or be considered "occult" causes of bleeding because classical diagnostic imaging often cannot exclude such injuries. The purpose of this narrative review article is to describe "occult" or unusual sources of bleeding associated with blunt trauma.

    DOI: 10.18926/AMO/55433

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  • Multiple liver abscesses caused by streptococcus constellatus. 査読

    Takeuchi N, Naito H, Yumoto T, Tsukahara K, Yamada T, Osako T, Soneda J, Nakao A.

    Surgical Infections Case Reports   2 ( 1 )   61 - 64   2017年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • A Successfully Treated Case of Criminal Thallium Poisoning. 査読 国際誌

    Yumoto T, Tsukahara K, Naito H, Iida A, Nakao A.

    case Rep Infect Dis   11 ( 4 )   OD01-OD02   2017年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.7860/JCDR/2017/24286.9494

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  • 右内頚静脈穿刺による脱血で体外膜型肺を併用し心肺蘇生を施行した4症例の検討. 査読

    野島宏悦, 内藤宏道, 小崎吉訓, 杉山淳一, 大谷晋吉, 川西進, 萩岡信吾, 森本直樹.

    日本集中治療医学会雑誌.   24 ( 2 )   131 - 135   2017年3月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:(一社)日本集中治療医学会  

    透視装置が使用できない状況下でも安全で短時間に送・脱血管を挿入するため、脱血管を右内頸静脈穿刺にて留置し、院外難治性心停止患者に対し体外膜型肺を併用した心肺蘇生法を行った。対象患者は4名、来院から体外循環開始までの時間は平均19.5(16[最小値]〜23[最大値])分で、ポンプ流量は2.5(1.2〜3.7)l/minであった。導入に伴う出血、虚血、感染、送・脱血管先端の誤留置は認めなかった。心拍再開までは十分なポンプ流量を確保できた。自己心拍再開後、1例で脱血不良のため大腿静脈からの脱血管再留置を行った。2例が体外膜型肺を離脱、1例が独歩で退院、3例が死亡した。本4症例では脱血管に径の小さい送血用カニューレを代用し、右内頸静脈穿刺で留置したため、脱血に制限があったものの、院外心停止患者に対し、合併症なく迅速に体外膜型肺を導入できた。(著者抄録)

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    その他リンク: https://search-tp.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2017&ichushi_jid=J02874&link_issn=&doc_id=20170403430005&doc_link_id=20181120430012&url=http%3A%2F%2Fsearch.jamas.or.jp%2Flink%2Fbc%2F20181120430012&type=jamaslink&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F99999_1.gif

  • Intraocular silicone oil masquerading as eye hemorrhage. 査読

    Yamakawa Y, Naito H, Tsukahara K, Iida A, Yumoto T, Yamada T, Osako T, Nakao A.

    J Trauma Treat   6 ( 1 )   360 - 361   2017年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • A successfully treated case of penetrating facial trauma. 査読

    Yumoto T, Iida A, Tsukahara K, Naito H, Terado M, Sato K, Date I, Nakao A.

    Int J Case Rep Images   8 ( 2 )   120 - 123   2017年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Staphylococcus aureus Bacteremia Complicated by Psoas Abscess and Infective Endocarditis in a Patient with Atopic Dermatitis

    Ichiro Tsuboi, Tetsuya Yumoto, Tatsuya Toyokawa, Katsunori Matsueda, Joichiro Horii, Hiromichi Naito, Atsunori Nakao

    Case Reports in Infectious Diseases   2017   1 - 4   2017年

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Hindawi Limited  

    The close relationship between atopic dermatitis (AD) and infective endocarditis (IE) has been implicated. <italic>Staphylococcus aureus</italic> colonization is frequently seen observed in AD patients’ skin lesions. Although a case of IE due to <italic>S. aureus</italic> bacteremia in an AD patient has been sporadically reported, a case of <italic>S. aureus</italic> bacteremia complicated by psoas abscess and IE has not been previously reported. A 42-year-old man with a history of AD presented to our hospital complaining of fever, fatigue, chills, lower right back pain, and poor appetite for a week. His blood cultures showed growth of <italic>S. aureus</italic>. On day 3, the patient presented acute cardiac failure and was diagnosed with IE based on echocardiogram examination. Since the patient’s cardiac failure did not respond to medication, an emergency surgery was performed on the fourth day of hospitalization. The patient underwent successful surgical treatment of the heart lesions and subsequent percutaneous drainage of psoas abscess and received intensive antibiotics, which successfully improved his condition. Our report emphasizes awareness of the association between AD and invasive <italic>S. aureus</italic> infections.

    DOI: 10.1155/2017/4920182

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    その他リンク: http://downloads.hindawi.com/journals/criid/2017/4920182.xml

  • Successfully-treated asymptomatic celiac artery aneurysm. A case report. 査読 国際誌

    Takeuchi N, Soneda J, Naito H, Iida A, Yumoto T, Tsukahara K, Nakao A.

    Int J Surg Case Rep   33   115 - 118   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijscr.2017.02.018

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  • A case of traumatic cardiopulmonary arrest with good neurological outcome predicted by amplitude-integrated electroencephalogram. 査読 国際誌

    Harada K, Tsukahara K, Yumoto T, Yamakawa Y, Iida A, Naito H, Nakao A.

    Int J Surg Case Rep   36   42 - 45   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijscr.2017.04.025

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  • A Successfully Treated Case of Criminal Thallium Poisoning 国際誌

    Tetsuya Yumoto

    JOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH   11 ( 4 )   OD01-OD02   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JCDR Research and Publications  

    Thallium was once commonly used as a household rodent or ant killer, but many countries have banned such use due to unintentional or criminal poisonings of humans. A common initial clinical manifestation of thallium poisoning is gastrointestinal symptoms followed by delayed onset of neurological symptoms and alopecia. These clinical characteristics can provide important diagnostic clues regarding thallium poisoning. Here, we report a 23-year-old woman who was poisoned by a business colleague when she unknowingly drank tea containing the toxic substance several times. The patient was treated with multi-dose activated charcoal with airway protection and Prussian blue.

    DOI: 10.7860/jcdr/2017/24286.9494

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  • Impact of Cushing's sign in the prehospital setting on predicting the need for immediate neurosurgical intervention in trauma patients 査読

    Tetsuya Yumoto*,Toshiharu Mitsuhashi*,Yasuaki Yamakawa*,Atsuyoshi Iida*,Nobuyuki Nosaka*,Kohei Tsukahara*,Hiromichi Naito*,Atsunori Nakao*

    Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine   24 ( 1 )   2016年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1186/s13049-016-0341-1

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  • Case of necrotizing fasciitis from streptococcus pyogenes (group A) treated successfully with negative-pressure wound therapy. 査読

    Inaba M, Nozaki S, Fujiwara T, Hongou T, Uozumi M, Nakahara T, Akagi Y, Kojima T, Naito H, Nakao A.

    Surgical Infections Case Reports.   1   142 - 145   2016年11月

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  • The Clinical Application of Hydrogen as a Medical Treatment. 査読

    Iida A, Nosaka N, Yumoto T. Knaup E. Naito H. Nishiyama C. Yamakawa Y. Tsukahara K. Terado M. Sato K. Ugawa T. Nakao A.

    Acta Med Okayama   70 ( 5 )   331 - 337   2016年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Okayama University Medical School  

    In recent years, it has become evident that molecular hydrogen is a particularyl effective treatment for various disease models such as ischemia-reperfusion injury; as a result, research on hydrogen has progressed rapidly. Hydrogen has been shown to be effective not only through intake as a gas, but also as a liquid medication taken orally, intravenously, or locally. Hydrogenʼs effectiveness is thus multifaceted. Herein we review the recent research on hydrogen-rich water, and we examine the possibilities for its clinical application. Now that hydrogen is in the limelight as a gaseous signaling molecule due to its potential ability to inhibit oxidative stress signaling, new research developments are highly anticipated.

    DOI: 10.18926/AMO/54590

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  • A successfully treated case of iliopsoas abscess affecting urinary tract infection caused by streptococcus sanguis. 査読

    Takeuchi N, Emori K, Yoshitani M, Soneda J, Naito H, Yumoto T, Tsukahara K, Nakao A.

    Surg Infect Case Rep.   1 ( 1 )   123 - 125   2016年9月

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  • Intraperitoneally administered, hydrogen-rich physiologic solution protects against postoperative ileus and is associated with reduced nitric oxide production 査読

    Ayana Okamoto,Keisuke Kohama,Michiko Aoyama-Ishikawa,Hayato Yamashita,Noritomo Fujisaki,Taihei Yamada,Tetsuya Yumoto*,Nobuyuki Nosaka*,Hiromichi Naito*,Kohei Tsukahara*,Atsuyoshi Iida*,Keiji Sato*,Joji Kotani,Atsunori Nakao*

    Surgery   160 ( 3 )   623 - 631   2016年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.surg.2016.05.026

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  • A successfully treated case of iliopsoas abscess affecting urinary tract infection caused by streptococcus sanguis. 査読

    Takeuchi N, Emori K, Yoshitani M, Soneda J, Naito H, Yumoto T, Tsukahara K, Nakao A

    Surgical Infections Case Reports.   1   41 - 43   2016年2月

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  • Soft tissue hematoma of the neck due to thyroid rupture with unusual mechanism 査読

    Kohei Tsukahara*,Keiji Sato*,Tetsuya Yumoto*,Atsuyoshi Iida*,Nobuyuki Nosaka*,Michihisa Terado*,Hiromichi Naito*,Yorihisa Orita*,Tomoyuki Naito,Kentaro Miki,Mayu Sugihara,Satoko Nagao,Toyomu Ugawa*,Atsunori Nakao*

    International Journal of Surgery Case Reports   26   217 - 220   2016年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ijscr.2016.08.002

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  • Effects of antibiotics administration on the incidence of wound infection in percutaneous dilatational tracheostomy. 査読

    Hagiya H, Naito H, Hagioka S, Okahara S, Morimoto N, Kusano

    Acta Med Okayama   68 ( 2 )   57 - 62   2014年8月

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  • Acute methemoglobinemia caused by suicidal ingestion of liquid fertilizer 査読

    Yasutoshi Kuroe, Hiromichi Naito, Junichi Sugiyama, Susumu Kawanishi, Naoki Morimoto, Shingo Hagioka

    Clinical Toxicology   52 ( 7 )   819 - 819   2014年8月

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    担当区分:責任著者   掲載種別:研究論文(学術雑誌)   出版者・発行元:Informa UK Limited  

    DOI: 10.3109/15563650.2014.932367

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  • Comprehensive Analysis of Systemically Disseminated ST8/non-USA300 type Community-acquired Methicillin-resistant Staphylococcus Aureus Infection. 査読

    Hagiya H, Hisatsune J, Kojima T, Shiota S, Naito H, Hagioka S, Morimoto N, Otsuka F, Sugai M.

    Intern Med.   53 ( 8 )   907 - 912   2014年3月

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  • Comprehensive Analysis of Systemically Disseminated ST8/non-USA300 type Community-acquired Methicillin-resistant Staphylococcus aureus Infection

    Hagiya Hideharu, Hisatsune Junzo, Kojima Taro, Shiota Sumiko, Naito Hiromichi, Hagioka Shingo, Morimoto Naoki, Otsuka Fumio, Sugai Motoyuki

    Internal Medicine   53 ( 8 )   907 - 912   2014年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Japanese Society of Internal Medicine  

    Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) is genetically heterogeneous and various genotypes are spreading worldwide. We herein report a case of systematically disseminated Japan-intrinsic CA-MRSA infection that was successfully treated. A genetically identical single strain was isolated from a total of 11 different parts of the patient's body, and the pathogen was found to be multilocus sequence type 8, staphylococcal cassette chromosome mec IV, coagulase type III and negative for both Panton-Valentine leukocidin and arginine catabolic mobile element. The epidemiology and pathogenicity of the Japan-intrinsic CA-MRSA strain remain unknown, and further investigation of this life-threatening organism is warranted.<br>

    DOI: 10.2169/internalmedicine.53.1746

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  • 重症呼吸不全に対するAirway Pressure Release Ventilationの肺酸素化能および循環動態に与える影響の検討. 査読

    岡原修司, 内藤宏道, 萩岡信吾, 森本直樹, 森松博史, 森田潔.

    ICUとCCU   37   219 - 223   2013年12月

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  • Quantitative evaluation of the neuroprotective effects of a short-acting β-adrenoceptor antagonist at a clinical dose on forebrain ischemia in gerbils: effects of esmolol on ischemic depolarization and histologic outcome of hippocampal CA1. 査読

    Danura T, Takeda Y, Shiraishi K, Naito H, Mizoue R, Sato S, Morita K.

    J Neurosurg Anesthesiol   25 ( 3 )   292 - 298   2013年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    BACKGROUND:Neuroprotective effects of esmolol in laboratory and clinical settings have been reported. The present study was designed to quantitatively evaluate the neuroprotective effects of esmolol using logistic regression curves and extracellular potentials.MATERIALS AND METHODS:In 42 gerbils, bilateral occlusion of common carotid arteries was performed for 3, 5, or 7 minutes (n=7 in each group). In treated animals, esmolol (200 µg/kg/min) was administered for 90 minutes, 30 minutes before the onset of ischemia. Direct current potentials were measured in the bilateral CA1 regions, in which histologic evaluation was performed 5 days later. Relations of neuronal damage with ischemic duration and duration of ischemic depolarization were determined using logistic regression curves.RESULTS:There was no significant difference in onset time between the 2 groups (the control group vs. the esmolol group: 1.65±0.46 vs. 1.68±0.45 min, P=0.76), and significant differences in durations of ischemic depolarization were not observed with any ischemic duration. However, logistic regression curves indicated that esmolol has a neuroprotective effect from 2.95 to 7.66 minutes of ischemic depolarization (P<0.05), and esmolol prolonged the duration of ischemic depolarization causing 50% neuronal damage from 4.97 to 6.34 minutes (P<0.05). Logistic regression curves also indicated that esmolol has a neuroprotective effect from 3.77 to 7.74 minutes of ischemic duration (P<0.05), and esmolol prolonged the ischemic duration causing 50% neuronal damage from 4.26 to 4.91 minutes (P<0.05).

    DOI: 10.1097/ana.0b013e31827fe3b1

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  • Effect of lidocaine on dynamic changes in cortical reduced nicotinamide adenine dinucleotide fluorescence during transient focal cerebral ischemia in rats 査読

    Naito H, Takeda Y, Danura T, Kass IS, Morita K.

    Neuroscience   235   59 - 69   2013年4月

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Rats were subjected to 90 min of focal ischemia by occluding the left middle cerebral and both common carotid arteries. The dynamic changes in the formation of brain ischemic areas were analyzed by measuring the direct current (DC) potential and reduced nicotinamide adenine dinucleotide (NADH) fluorescence with ultraviolet irradiation. In the lidocaine group (n = 10), 30 min before ischemia, an intravenous bolus (1.5 mg/kg) of lidocaine was administered, followed by a continuous infusion (2 mg/kg/h) for 150 min. In the control group (n = 10), an equivalent amount of saline was administered. Following the initiation of ischemia, an area of high-intensity NADH fluorescence rapidly developed in the middle cerebral artery territory in both groups and the DC potential in this area showed ischemic depolarization. An increase in NADH fluorescence closely correlated with the DC depolarization. The blood flow in the marginal zone of both groups showed a similar decrease. Five minutes after the onset of ischemia, the area of high-intensity NADH fluorescence was significantly smaller in the lidocaine group (67% of the control; P = 0.01). This was likely due to the suppression of ischemic depolarization by blockage of voltage-dependent sodium channels with lidocaine. Although lidocaine administration did not attenuate the number of pen-infarct depolarizations during ischemia, the high-intensity area and infarct volume were significantly smaller in the lidocaine group both at the end of ischemia (78% of the control; P = 0.046) and 24 h later (P = 0.02). A logistic regression analysis demonstrated a relationship between the duration of ischemic depolarization and histologic damage and revealed that lidocaine administration did not attenuate neuronal damage when the duration of depolarization was identical. These findings indicate that the mechanism by which lidocaine decreases infarct volume is primarily through a reduction of the brain area undergoing NADH fluorescence increases which closely correlates with depolarization.

    DOI: 10.1016/j.neuroscience.2013.01.010

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  • In Reply: 国際誌

    Yoshimasa Takeda, Hiroshi Hashimoto, Koji Fumoto, Tetsuya Danura, Hiromichi Naito, Naoki Morimoto, Hiroshi Katayama, Soichiro Fushimi, Akihiro Matsukawa, Aiji Ohtsuka, Kiyoshi Morita

    Anesthesiology   118 ( 2 )   469 - 470   2013年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Ovid Technologies (Wolters Kluwer Health)  

    DOI: 10.1097/aln.0b013e31827e3c53

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  • Emphysematous liver abscesses complicated by septic pulmonary emboli in patients with diabetes: two cases. 査読

    Hagiya H, Kuroe Y, Nojima H, Otani S, Sugiyama J, Naito H, Kawanishi S, Hagioka S, Morimoto N.

    Intern Med.   52 ( 1 )   141 - 145   2013年2月

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  • A Fatal case of streptococcal toxic shock syndrome due to Streptococcus dysgalactiae subsp. equisimilis possibly caused by an intramuscular injection. 査読

    Hagiya H, Okita S, Kuroe Y, Nojima H, Otani S, Sugiyama J, Naito H, Kawanishi S, Hagioka S, Morimoto N.

    Intern Med.   52 ( 3 )   397 - 402   2013年2月

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  • Delftia acidovorans bacteremia caused by bacterial translocation after organophosphorus poisoning in an immunocompetent adult patient. 査読 国際誌

    Hagiya H, Murase T, Sugiyama J, Kuroe Y, Nojima H, Naito H, Hagioka S, Morimoto N.

    J Infect Chemother.   19 ( 2 )   338 - 341   2013年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10156-012-0472-x

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  • Emphysematous Liver Abscesses Complicated by Septic Pulmonary Emboli in Patients with Diabetes: Two Cases

    Hagiya Hideharu, Kuroe Yasutoshi, Nojima Hiroyoshi, Otani Shinkichi, Sugiyama Junichi, Naito Hiromichi, Kawanishi Susumu, Hagioka Shingo, Morimoto Naoki

    Internal Medicine   52 ( 1 )   141 - 145   2013年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Japanese Society of Internal Medicine  

    An emphysematous liver abscess is a fatal condition that often occurs in patients with uncontrolled diabetes mellitus. I herein describe two cases of Klebsiella pneumoniae-induced emphysematous liver abscesses complicated by septic pulmonary emboli in patients with poorly controlled diabetes mellitus. Both patients showed hemoglobin A1c levels of more than 10% and did not present with any abdominal symptoms on admission. However, they were diagnosed and successfully treated with percutaneous transhepatic abscess drainage and antibiotics. This fatal disease should be taken into consideration in patients with uncontrolled diabetes mellitus who suffer from prolonged fevers and uncharacteristic general malaise.<br>

    DOI: 10.2169/internalmedicine.52.8737

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  • A Fatal Case of Streptococcal Toxic Shock Syndrome due to Streptococcus dysgalactiae subsp. equisimilis Possibly Caused by an Intramuscular Injection

    Hagiya Hideharu, Okita Shunji, Kuroe Yasutoshi, Nojima Hiroyoshi, Otani Shinkichi, Sugiyama Junichi, Naito Hiromichi, Kawanishi Susumu, Hagioka Shingo, Morimoto Naoki

    Internal Medicine   52 ( 3 )   397 - 402   2013年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Japanese Society of Internal Medicine  

    An 88-year-old man died of streptococcal toxic shock syndrome due to a group G streptococcus infection that was possibly caused by an intramuscular injection given 30 hours earlier in his right deltoid muscle. The causative pathogen was later identified to be Streptococcus dysgalactiae subsp. equisimilis (stG485). Although providing intramuscular injections is an essential skill of health care workers that is performed daily worldwide, it may constitute a port of entry for pathogens via skin breaches that can cause life-threatening infections. All invasive procedures should be carefully performed, especially when immunologically compromised patients are involved.<br>

    DOI: 10.2169/internalmedicine.52.8846

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  • Co-infection with invasive pulmonary aspergillosis and Pneumocystis jirovecii pneumonia after corticosteroid therapy. 査読 国際誌

    Hagiya H, Miyake T, Kokumai Y, Murase T, Kuroe Y, Nojima H, Sugiyama J, Naito H, Hagioka S, Morimoto N.

    J Infect Chemother.   19 ( 2 )   342 - 347   2013年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1007/s10156-012-0473-9

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  • Effects of pharyngeal cooling on brain temperature in primates and humans 査読

    Takeda Y, Hashimoto H, Fumoto K, Danura T, Naito H, Morimoto N, Katayama H, Fushimi S, Matukawa A, Ohtsuka A, Morita K.

    Anesthesiology   117   2012年12月

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  • Necrotizing duodenitis caused by Clostridium perfringens type A in a Japanese young man. 査読

    Hagiya H, Naito H, Sugiyama J, Nojima H, Hagioka S, Morimoto N.

    Intern Med.   51 ( 20 )   2973 - 2976   2012年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Severe soft tissue Infection of the lower extremity caused by Haemophilus influenzae (serotype f, biotype II) in an adult patient. 査読

    Hagiya H, Murase T, Naito H, Hagioka S, Morimoto N.

    Intern Med.   51 ( 13 )   1783 - 1787   2012年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

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  • Effects of Pharyngeal Cooling on Brain Temperature in Primates and Humans 査読 国際誌

    Yoshimasa Takeda, Hiroshi Hashimoto, Koji Fumoto, Tetsuya Danura, Hiromichi Naito, Naoki Morimoto, Hiroshi Katayama, Soichiro Fushimi, Akihiro Matsukawa, Aiji Ohtsuka, Kiyoshi Morita

    Anesthesiology   117 ( 1 )   117 - 125   2012年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Ovid Technologies (Wolters Kluwer Health)  

    <sec>
    <title>Background</title>
    Pharyngeal cooling decreases brain temperature by cooling carotid arteries. This study was designed to evaluate the principle of pharyngeal cooling in monkeys and humans.


    </sec>
    <sec>
    <title>Methods</title>
    Monkeys (n = 10) were resuscitated following 12 min of cardiac arrest. Pharyngeal cooling (n = 5), in which cold saline (5°C) was perfused into the cuff at the rate of 500 ml/min, was initiated simultaneously with the onset of resuscitation for 30 min. Patients (n = 3) who were in an intensive care unit were subjected to 30 min of pharyngeal cooling under propofol anesthesia.


    </sec>
    <sec>
    <title>Results</title>
    In the animal study, core brain temperature was significantly decreased compared with that in the control group by 1.9°C (SD = 0.8, P &amp;lt; 0.001) and 3.1°C (SD = 1.0, P &amp;lt; 0.001) at 10 min and 30 min after the onset of cooling, respectively. The cooling effect was more evident in an animal with low postresuscitation blood pressure. Total dose of epinephrine, number of direct current shocks, and recovery of blood pressure were not different between the two groups. The pharyngeal epithelium was microscopically intact on day 5. In the clinical study, insertion of the cuff and start of perfusion did not affect heart rate or blood pressure. Tympanic temperature was decreased by 0.6 ± 0.1°C/30 min without affecting bladder temperature. The pharynx was macroscopically intact for 3 days.


    </sec>
    <sec>
    <title>Conclusions</title>
    Pharyngeal cooling rapidly and selectively decreased brain temperature in primates and tympanic temperature in humans and did not have adverse effects on return of spontaneous circulation, even when initiated during cardiac arrest in primates.


    </sec>

    DOI: 10.1097/aln.0b013e3182580536

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  • ALI/ARDSに対するNPPV成功の予測因子の検討. 査読

    岡原修司, 内藤宏道, 萩岡信吾, 萩谷英大, 杉山淳一, 勝田知也, 森本直樹.

    日本救急医学会雑誌   23   768 - 774   2012年6月

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  • 急性上腸間膜動脈閉塞症における予後に関わる因子の検討 査読

    西田傑, 萩岡信吾, 内藤宏道, 杉山雅俊, 森本直樹.

    日本集中治療医学会雑誌   19 ( 1 )   33 - 37   2012年1月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Japanese Society of Intensive Care Medicine  

    【目的】急性上腸間膜動脈閉塞症の予後に関わる因子を検討する。【方法】当院で経験した急性上腸間膜動脈閉塞症症例27例を28日生存群と死亡群に分け,患者背景,血液検査所見,所要時間を予後に関わる可能性のある因子として抽出した。【結果】死亡群では,Acute Physiology and Chronic Health Evaluation II(APACHE II)スコア18.2±6.4,乳酸値8.1±4.3 mmol/l,クレアチニン2.3±1.1 mg/dlが生存群に対して有意に高値だった。症状発現から治療開始までの時間は死亡群,生存群ともに15時間で変わらなかった。【結論】症状発現から治療開始までの時間は予後とは関わっておらず,クレアチニン,乳酸値が予後の指標として使用できる可能性が考えられた。

    DOI: 10.3918/jsicm.19.33

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  • Severe Soft Tissue Infection of the Lower Extremity Caused by Haemophilus influenzae (serotype f, biotype II) in an Adult Patient 査読

    Hagiya Hideharu, Murase Tomoko, Naito Hiromichi, Hagioka Shingo, Morimoto Naoki

    Internal Medicine   51 ( 13 )   1783 - 1787   2012年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Japanese Society of Internal Medicine  

    The infection caused by non-b-type Haemophilus influenzae has been increasing in this Hib (H.influenzae serotype b) vaccination era. H.influenzae serotype f (Hif) is considered as one of those emerging pathogens. In general, H.influenzae is a common pathogen of such as pneumonia, otitis media, and meningitis, but is rare in soft tissue infection, especially at the extremity. We report a rare case of severe soft tissue infection caused by Hif which occurred at the lower extremity of immunocompetent adult patient.<br>

    DOI: 10.2169/internalmedicine.51.7209

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  • Necrotizing Duodenitis Caused by Clostridium perfringens Type A in a Japanese Young Man

    Hagiya Hideharu, Naito Hiromichi, Sugiyama Junichi, Nojima Hiroyoshi, Hagioka Shingo, Morimoto Naoki

    Internal Medicine   51 ( 20 )   2973 - 2976   2012年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Japanese Society of Internal Medicine  

    A 21-year-old Japanese man with a history of marked body weight loss over a short period of time died of necrotizing duodenitis caused by Clostridium perfringens (C. perfringens) type A. C. perfringens type A is considered to usually cause self-limiting gastroenteritis. Necrotizing enteritis sometimes occurs due to C. perfringens in developing countries; however, it is primarily caused by the type C strain and its site of onset is typically the jejunum or ileum. This is a rare case of necrotizing duodenitis caused by C. perfringens type A in a Japanese young man. Physicians need to be more aware of this emerging fatal disease in developed countries.<br>

    DOI: 10.2169/internalmedicine.51.8407

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  • 症例報告 除草剤(ラッソー乳剤)服用後,長期間にわたり痙攣が持続した1例

    内藤 宏道, 長江 正晴, 岡原 修司

    中毒研究   24 ( 1 )   35 - 38   2011年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:へるす出版  

    Scopus

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  • 症例報告 陽イオン界面活性剤を含む中性洗剤(HDQ Neutral)の誤飲により上気道狭窄をきたした1症例

    長江 正晴, 内藤 宏道, 岡原 修司

    中毒研究   24 ( 1 )   39 - 41   2011年

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)   出版者・発行元:へるす出版  

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    CiNii Article

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  • 重症ARDSに対するステロイド療法の検討 査読

    萩岡信吾, 長江正晴, 内藤宏道, 石井智子, 森本直樹, 笠井慎也, 杉山雅俊

    ICUとCCU   33   403 - 408   2009年5月

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    記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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  • マムシ咬傷48例の検討 ?初診時の腫脹の程度は重症度を反映するか 査読

    内藤宏道, 松本和幸, 長江正晴, 笠井慎也, 白石建輔, 森本直樹, 萩岡信吾, 杉山雅俊

    中毒研究   20   31 - 35   2007年10月

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    担当区分:筆頭著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)  

    CiNii Article

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  • 当院における外傷症例の分析 -日本外傷データバンク事業への参加- 査読

    内藤宏道, 長江正晴, 笠井慎也, 白石建輔, 森本直樹

    津山中央病院医学雑誌   20   27 - 31   2006年9月

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    担当区分:筆頭著者   記述言語:日本語   掲載種別:研究論文(学術雑誌)  

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▼全件表示

書籍等出版物

  • 救急救命スタッフのためのITLS

    Alson,Roy L., Han,Kyee H., Campbell, John E., ITLS日本支部( 担当: 共訳 ,  範囲: 脊椎・脊髄損傷と傷病者を中心に考えた脊髄運動制限)

    メディカ出版  2021年9月  ( ISBN:9784840475846

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    総ページ数:xxii, 464p   記述言語:日本語

    CiNii Books

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  • Neuroanesthesia and cerebrospinal protection

    Naito H, Morimoto N( 担当: 共著)

    Springer  2015年8月  ( ISBN:9784431544906

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    記述言語:英語

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  • 心拍再開後ケアと低体温描法 トレーニング・マニュアル

    内藤宏道, 武田吉正( 担当: 共著)

    日本蘇生協議会編  2015年5月  ( ISBN:9784906502714

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    記述言語:日本語

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MISC

  • レボチロキシン多量服薬の一例

    小崎 吉訓, 内藤 宏道, 小出 恭大, 塚原 紘平, 湯本 哲也, 中尾 篤典

    日本臨床救急医学会雑誌   26 ( 3 )   351 - 351   2023年7月

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    記述言語:日本語   出版者・発行元:(一社)日本臨床救急医学会  

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  • 救急医療現場における個人的信念に基づく医療行為拒否への対応 放射線被曝拒否事例から考える

    小出 恭大, 湯本 哲也, 本郷 貴識, 小崎 吉訓, 野島 剛, 上田 浩平, 小原 隆史, 飯田 淳義, 山本 浩継, 青景 聡之, 塚原 紘平, 内藤 宏道, 中尾 篤典

    日本臨床救急医学会雑誌   26 ( 3 )   358 - 358   2023年7月

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    記述言語:日本語   出版者・発行元:(一社)日本臨床救急医学会  

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  • アセトアミノフェン中毒におけるプロカルシトニンの有用性

    野島 剛, 本郷 貴識, 小原 隆史, 小崎 吉訓, 飯田 淳義, 湯本 哲也, 青景 聡之, 塚原 紘平, 内藤 宏道, 中尾 篤典

    中毒研究   36 ( 2 )   207 - 207   2023年7月

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    記述言語:日本語   出版者・発行元:(株)へるす出版  

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  • 集中治療領域での嚥下障害

    本郷 貴識, 小原 隆史, 野島 剛, 上田 浩平, 青景 聡之, 塚原 紘平, 湯本 哲也, 内藤 宏道, 中尾 篤典

    日本集中治療医学会雑誌   30 ( Suppl.1 )   S269 - S269   2023年6月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • つなぐいのち~小児脳死下臓器ドナー管理 小児脳死下臓器ドナー管理の特徴 当センターでの経験から

    小原 隆史, 内藤 宏道, 塚原 紘平, 野島 剛, 上田 浩平, 本郷 貴識, 小崎 吉訓, 山本 浩継, 青景 聡之, 湯本 哲也, 中尾 篤典

    日本集中治療医学会雑誌   30 ( Suppl.1 )   S283 - S283   2023年6月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 当科における小児急性脳症と体温管理療法の現状

    小原 隆史, 塚原 紘平, 平岡 知浩, 本郷 貴識, 湯本 哲也, 内藤 宏道, 中尾 篤典

    日本脳低温療法・体温管理学会誌   26 ( 1 )   47 - 47   2023年6月

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    記述言語:日本語   出版者・発行元:日本脳低温療法・体温管理学会  

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  • 体温管理療法中の温度管理が筋萎縮にあたえる影響の検討

    本郷 貴識, 小原 隆史, 湯本 哲也, 内藤 宏道, 中尾 篤典

    日本脳低温療法・体温管理学会誌   26 ( 1 )   48 - 48   2023年6月

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    記述言語:日本語   出版者・発行元:日本脳低温療法・体温管理学会  

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  • つなぐ命と気持ち~脳死移植における集中治療の役割~潜在的なドナーの認知から移植外科医につなげるところまで 終末期の児童に対し「臓器移植の情報提供」を含めた選択肢提示を行うために 当院の体制作りと現状

    塚原 紘平, 小原 隆史, 野島 剛, 上田 浩平, 本郷 貴識, 小崎 吉訓, 山本 浩継, 飯田 淳義, 青景 聡之, 湯本 哲也, 内藤 宏道, 中尾 篤典

    日本集中治療医学会雑誌   30 ( Suppl.1 )   S331 - S331   2023年6月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 小児の院外心停止における医師の病院前救急診療は神経学的転帰を改善する

    小原 隆史, 湯本 哲也, 塚原 紘平, 野島 剛, 本郷 貴識, 松本 尚美, 頼藤 貴志, 中尾 篤典, 内藤 宏道

    日本集中治療医学会雑誌   30 ( Suppl.1 )   S422 - S422   2023年6月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • おもり自由落下装置を用いた慢性頭部外傷性脳症モデルの作成 高い再現性と定量性を求めて

    菅原 千明, 安原 隆雄, 平山 隆浩, 正井 加織, 佐々田 晋, 河内 哲, 藪野 諭, 永瀬 喬之, 佐々木 達也, 内藤 宏道, 浅沼 幹人, 伊達 勲

    日本脳神経外傷学会プログラム・抄録集   46回   119 - 119   2023年2月

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    記述言語:日本語   出版者・発行元:(一社)日本脳神経外傷学会  

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  • 脳死の状態判断に補助検査として脳血流シンチグラフィを施行した1例

    庵谷 紘美, 内藤 宏道, 小原 隆史, 青景 聡之, 塚原 紘平, 中尾 篤典

    日本集中治療医学会雑誌   29 ( Suppl.1 )   667 - 667   2022年11月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 臓器移植におけるドナー管理(臓器保護の観点から) 6歳未満おける臓器移植ドナー管理の特徴

    小原 隆史, 内藤 宏道, 塚原 紘平, 青景 聡之, 野島 剛, 上田 浩平, 小崎 吉訓, 山田 太平, 藤崎 宣友, 中尾 篤典

    日本集中治療医学会雑誌   29 ( Suppl.1 )   297 - 297   2022年11月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 地域枠制度・地域医療に対する持続的発展を担う救急医療教育

    野島 剛, 湯本 哲也, 小崎 吉訓, 長谷川 徹, 塚原 紘平, 内藤 宏道, 小川 弘子, 佐藤 勝, 忠田 正樹, 中尾 篤典

    日本救急医学会雑誌   33 ( 10 )   850 - 850   2022年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 水素含有臓器保護液は,虚血再灌流後のミトコンドリアの機能回復を早め,細胞死を軽減する

    瀬谷 海月, 青景 聡之, 山田 太平, 渡邉 暁洋, 山本 浩継, 平山 隆浩, 野島 剛, 中尾 篤典, 内藤 宏道

    日本救急医学会雑誌   33 ( 10 )   891 - 891   2022年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 産科情報共有システム「iPicss」により迅速な対応ができた出産中の脳出血の搬送例

    佐々並 三紗, 小崎 吉訓, 塚原 紘平, 牧 尉太, 中尾 篤典, 内藤 宏道, 湯本 哲也, 上田 浩平, 小原 隆史, 本郷 貴識, 平岡 知浩

    日本救急医学会雑誌   33 ( 10 )   806 - 806   2022年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 医学生による女性型シミュレーターを用いた蘇生実習の検討

    久保 卓也, 本郷 貴識, 塚原 紘平, 野島 剛, 小崎 吉訓, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   33 ( 10 )   875 - 875   2022年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 組織の体制整備による持続可能な「臓器提供」

    塚原 紘平, 平岡 知浩, 薬師寺 泰匡, 小原 隆史, 小崎 吉訓, 野島 剛, 湯本 哲也, 山本 浩継, 青景 聡之, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   33 ( 10 )   847 - 847   2022年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 治療的医学ガス(Medical gas)を救急集中治療領域へ応用する 救急医による挑戦

    小原 隆史, 青景 聡之, 山本 浩継, 野島 剛, 上田 浩平, 湯本 哲也, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   33 ( 10 )   823 - 823   2022年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • デジタル田園健康特区における救急救命士の権限・役割の拡大による救急体制の充実への取り組み

    上田 浩平, 本郷 貴識, 小原 隆史, 野島 剛, 湯本 哲也, 塚原 紘平, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   33 ( 10 )   872 - 872   2022年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 院外心停止例での体温管理療法に関する無作為化比較試験

    内藤 宏道, 錦見 満暁, 岡田 遥平, 前山 博輝, 木口 雄之, 西田 一貴, 松井 茂之, 黒田 泰弘, 西山 慶, 石見 拓, 中尾 篤典

    日本脳低温療法・体温管理学会誌   25 ( 1 )   12 - 13   2022年9月

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    記述言語:日本語   出版者・発行元:日本脳低温療法・体温管理学会  

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  • 院外心停止例での体温管理療法に関する無作為化比較試験

    内藤 宏道, 錦見 満暁, 岡田 遥平, 前山 博輝, 木口 雄之, 西田 一貴, 松井 茂之, 黒田 泰弘, 西山 慶, 石見 拓, 中尾 篤典

    日本脳低温療法・体温管理学会誌   25 ( 1 )   12 - 13   2022年9月

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    記述言語:日本語   出版者・発行元:日本脳低温療法・体温管理学会  

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  • 委員会報告:脳死下臓器提供におけるアンケート調査~脳死判定を目的とした転院搬送の考察をふまえて~ 査読

    一般社団法人日本救急医学会, 脳死, 臓器組織移植に関する委員会, 委員長, 横堀將司, 委員, 横田裕行, 渥美生弘, 黒田泰弘, 内藤宏道, 西山慶, 林宗博, 平尾朋仁, 本多ゆみえ, 師岡誉也, 吉川美喜子, 稲田眞治, 小野元, 伊藤友弥, 江川裕子, 沢本圭悟, 岩永航

    日本救急医学会雑誌   33 ( 8 )   421 - 435   2022年7月

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    記述言語:日本語   掲載種別:記事・総説・解説・論説等(学術雑誌)   出版者・発行元:(一社)日本救急医学会  

    新型コロナウイルス感染症蔓延下において脳死下臓器提供数が減少しているなかで,脳死判定を目的とした転院搬送の是非に関する議論が始まっている。これをふまえ,全国救命センターにおけるコロナ禍での脳死判定や脳死下臓器移植に関わる現状と問題点を調査した。全国救命センター295施設に質問紙URLを送付し電子的に回収した。調査項目は施設背景,臓器提供の意思決定に関する質問,臓器提供も見据えた患者管理,脳死判定,臓器提供手術の問題点に関する質問,臓器提供を目的とした転院に関する質問とした。220施設より回答を得た(回答率74.6%)。コロナ禍において臓器提供を施行した施設は45施設(20.5%)存在した。臓器提供を行った施設とそうでなかった施設において,休日夜間帯に勤務をしている専門医数に差が見られた(平均3.04人対2.44人)。また,コロナ禍によって臓器提供に関する事項が影響を受けたと回答した施設は全国救命センターの43施設(19.6%)に及び,患者個室管理,家族の面会制限,チームの参集困難など,感染対策による影響と回答した施設がうち39施設(90.7%)に見られた。「脳死下臓器提供」を目的とした転院に関し,他施設に転送したいと回答した施設群(60施設:27%)は,院内連携が手薄く,マンパワーが少なく,また,脳死判定医が少ないこと,脳死判定の費用に関わる経済的問題に要因があると思われた。本研究によりコロナ禍における脳死下臓器提供に関わるハード,ソフト両面の課題が明確になった。とくに施設におけるマンパワー拡充のための施設間連携と経済的支援の拡充が今後の課題であると思われた。(著者抄録)

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  • キノコ中毒におけるプロカルシトニンによる診断は有用か

    野島 剛, 湯本 哲也, 小崎 吉訓, 小原 隆史, 上田 浩平, 塚原 紘平, 山田 太平, 内藤 宏道, 中尾 篤典

    中毒研究   35 ( 2 )   153 - 153   2022年7月

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    記述言語:日本語   出版者・発行元:(株)へるす出版  

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  • 前頸部の腫脹によるICP上昇に対し厳密な体位保持が有用であった重症頭部外傷の小児例

    小原 隆史, 塚原 紘平, 山本 浩継, 内藤 宏道, 中尾 篤典

    日本小児救急医学会雑誌   21 ( 2 )   287 - 287   2022年6月

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    記述言語:日本語   出版者・発行元:(一社)日本小児救急医学会  

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  • 日本外傷学会データバンクを用いた熱傷症例の検討

    野島 剛, 内藤 宏道, 小原 隆史, 小崎 吉訓, 上田 浩平, 塚原 紘平, 中尾 篤典

    熱傷   48 ( 1 )   38 - 39   2022年3月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 当院高度救命救急センターにおける小児の熱傷と感染に関するまとめ

    小原 隆史, 塚原 紘平, 野島 剛, 上田 浩平, 山本 浩継, 内藤 宏道, 中尾 篤典

    熱傷   48 ( 1 )   41 - 41   2022年3月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 当院高度救命救急センターにおける小児の熱傷と感染に関するまとめ

    小原 隆史, 塚原 紘平, 野島 剛, 上田 浩平, 山本 浩継, 内藤 宏道, 中尾 篤典

    熱傷   48 ( 1 )   41 - 41   2022年3月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 広範囲熱傷患者のエネルギー消費の経過

    大塚 貴久, 塚原 絋平, 内藤 宏道, 中尾 篤典

    熱傷   48 ( 1 )   38 - 38   2022年3月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 日本外傷学会データバンクを用いた熱傷症例の検討

    野島 剛, 内藤 宏道, 小原 隆史, 小崎 吉訓, 上田 浩平, 塚原 紘平, 中尾 篤典

    熱傷   48 ( 1 )   38 - 39   2022年3月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 当院EICUにおいて、熱傷患者の熱傷面積が広いほど緑膿菌は検出されるかの検証

    木口 隆, 加藤 湖月, 野島 剛, 小崎 吉訓, 藤崎 宣友, 塚原 紘平, 内藤 宏道, 中尾 篤典

    熱傷   48 ( 1 )   40 - 40   2022年3月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 岡山市における重症熱傷患者搬送とコロナウイルス感染症の影響

    上田 浩平, 内藤 宏道, 塚原 紘平, 中尾 篤典

    熱傷   48 ( 1 )   39 - 39   2022年3月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 臨床工学技士が迎え搬送に携わった経験と今後の課題

    岡田真澄, 落葉佑昌, 高寛, 平山隆浩, 上田浩平, 青景聡之, 塚原紘平, 内藤宏道, 中尾篤典

    日本集中治療医学会中国・四国支部学術集会プログラム・抄録集(Web)   6th   2022年

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  • DNAR指示を有する院外心停止の特徴,病院前処置,転機に関する検討

    田邉綾, 内藤宏道, 野島剛, 塚原紘平, 山田太平, 中尾篤典

    日本臨床救急医学会雑誌   25 ( 2 )   2022年

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  • 水素吸入は高齢者敗血症の予後を改善させるか? 老齢・LPSモデルマウスを用いた検証

    青景 聡之, 池谷 真澄, 藤崎 宣友, 大澤 郁朗, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   32 ( 12 )   1738 - 1738   2021年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

    J-GLOBAL

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  • 巨大地震急性期対応で国際NGOが果たす役割

    稲葉 基高, 坂田 大三, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   32 ( 12 )   1362 - 1362   2021年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 【Challenge to Change】救急医療における終末期医療 フレイルが高齢者の救急集中治療の予後に及ぼす影響(最終報告)

    稲葉 基高, 内藤 宏道, 真弓 俊彦, 中尾 篤典

    日本救急医学会雑誌   32 ( 12 )   1034 - 1034   2021年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 高齢者救急医療の問題点(各部門からの本音が聞きたい) 高齢者救急集中治療の予後から見たフレイルの重要性

    稲葉 基高, 内藤 宏道, 中尾 篤典

    日本在宅医療連合学会大会プログラム・講演抄録集   3回   154 - 154   2021年11月

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    記述言語:日本語   出版者・発行元:(一社)日本在宅医療連合学会  

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  • 蘇生実習における性差教育が与えるインパクト

    谷田 貴, 折田 沙穂, 塚原 紘平, 中村 俊介, 久保 卓也, 小崎 吉訓, 野島 剛, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   32 ( 12 )   2703 - 2703   2021年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 神経集中治療〜脳と全身管理のコラボレーション〜 小児急性脳症バンドルによる神経学予後改善への挑戦

    塚原 紘平, 小原 隆史, 山本 浩継, 野島 剛, 上田 浩平, 小崎 吉訓, 藤崎 宣友, 青景 聡之, 内藤 宏道, 中尾 篤典

    日本集中治療医学会雑誌   28 ( Suppl.2 )   257 - 257   2021年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 一酸化炭素遊離分子(CORM)管腔内投与による小腸移植グラフト保存への新しいアプローチ

    小原 隆史, 山本 浩継, 青景 聡之, 内藤 宏道, 中尾 篤典

    移植   56 ( 総会臨時 )   O26 - 4   2021年9月

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    記述言語:日本語   出版者・発行元:(一社)日本移植学会  

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  • コロナ禍における面会制限は脳死下臓器提供に影響を与えたか? 岡山大学病院高度救命救急センターの経験から

    萩原 万瀧, 塚原 紘平, 中村 俊介, 小崎 吉訓, 小田 裕太, 小原 隆史, 上田 浩平, 野島 剛, 山本 浩継, 山田 太平, 青景 聡之, 藤崎 宣友, 内藤 宏道, 中尾 篤典

    移植   56 ( 総会臨時 )   O25 - 1   2021年9月

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    記述言語:日本語   出版者・発行元:(一社)日本移植学会  

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  • PCASに対する脳保護療法:TTMの普及とスタンダード 来院時アンモニア値に搬送時間を加味した院外心停止患者の予後予測

    野島 剛, 内藤 宏道, 小崎 吉訓, 小原 隆史, 山本 浩継, 藤崎 宣友, 青景 聡之, 塚原 紘平, 山田 太平, 中尾 篤典

    日本集中治療医学会雑誌   28 ( Suppl.2 )   223 - 223   2021年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • ラット小腸移植モデルを使った水素含有生理食塩水の管腔内投与による臓器保護効果の検討

    山本 浩継, 小原 隆史, 青景 聡之, 井川 卓朗, 内藤 宏道, 中尾 篤典

    移植   56 ( 総会臨時 )   O26 - 5   2021年9月

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    記述言語:日本語   出版者・発行元:(一社)日本移植学会  

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  • 日本版敗血症ガイドライン2020;初期蘇生・ステロイドを知る 初期蘇生・循環作動薬班のエビデンス解説

    櫻谷 正明, 廣瀬 智也, 垣花 泰之, 松嶋 麻子, 高橋 弘, 田上 隆, 松山 匡, 大下 慎一郎, 下山 哲, 岡本 潤, 山田 浩平, 舩越 拓, 青木 誠, 村田 哲平, 西山 慶, 中森 裕毅, 宮崎 裕也, 内藤 宏道, 安部 隆国, 入野田 崇, 岡 和幸, 角山 泰一朗, 原口 剛, 石川 雅巳, 石丸 剛, 吉廣 尚大, 古川 彩香, 江木 盛時, 小倉 裕司, 西田 修, 田中 裕, J-SSCG2020特別委員会

    日本集中治療医学会雑誌   28 ( Suppl.2 )   225 - 225   2021年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 日本版敗血症ガイドライン2020;初期蘇生・ステロイドを知る 初期蘇生・循環作動薬班のエビデンス解説

    櫻谷 正明, 廣瀬 智也, 垣花 泰之, 松嶋 麻子, 高橋 弘, 田上 隆, 松山 匡, 大下 慎一郎, 下山 哲, 岡本 潤, 山田 浩平, 舩越 拓, 青木 誠, 村田 哲平, 西山 慶, 中森 裕毅, 宮崎 裕也, 内藤 宏道, 安部 隆国, 入野田 崇, 岡 和幸, 角山 泰一朗, 原口 剛, 石川 雅巳, 石丸 剛, 吉廣 尚大, 古川 彩香, 江木 盛時, 小倉 裕司, 西田 修, 田中 裕, J-SSCG2020特別委員会

    日本集中治療医学会雑誌   28 ( Suppl.2 )   225 - 225   2021年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • ここまできたPICS研究 敗血症治療後の嚥下障害の頻度、特徴、転帰(Frequency, Characteristics, and Outcomes of Dysphagia Following Sepsis Treatment)

    本郷 貴識, 内藤 宏道, 藤原 俊文, 赤木 洋介, 伏見 美紀, 難波 研二, 小林 洋二, 水川 俊一, 中尾 篤典

    日本集中治療医学会雑誌   28 ( Suppl.2 )   291 - 291   2021年9月

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    記述言語:英語   出版者・発行元:(一社)日本集中治療医学会  

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  • 早期血管内治療を必要とした鋭的外傷による大動脈瘤の一例

    中村 俊介, 山田 太平, 野島 剛, 小崎 吉訓, 内藤 宏道, 中尾 篤典

    日本外傷学会雑誌   35 ( 2 )   156 - 156   2021年5月

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    記述言語:日本語   出版者・発行元:(一社)日本外傷学会  

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  • 幼児期の睡眠不足は学童期のケガのリスクとなる(21世紀出生児縦断コホート研究)

    小原 隆史, 塚原 紘平, 山本 浩継, 松本 尚美, 頼藤 貴志, 内藤 宏道, 中尾 篤典

    日本小児科学会雑誌   125 ( 2 )   224 - 224   2021年2月

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    記述言語:日本語   出版者・発行元:(公社)日本小児科学会  

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  • 非特定警戒地域における新型コロナウイルス流行下の小児救急搬送の状況変化

    小原 隆史, 塚原 紘平, 上田 浩平, 内藤 宏道, 頼藤 貴志, 中尾 篤典

    日本小児救急医学会雑誌   20 ( 1 )   70 - 72   2021年2月

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    記述言語:日本語   出版者・発行元:(一社)日本小児救急医学会  

    (目的)Coronavirus disease 2019(COVID-19)の流行期、非特定警戒都道府県である岡山市の小児救急搬送の現状を検討した。(方法)2019・2020年の2〜5月に同市消防局内で、転院を除いた18歳未満を対象に後方視的観察研究を行った。(結果)4、5月の搬送数は前年比の半数以下、発熱を有する搬送も減っていた。重症例に変化はなく、軽症・中等症の減少が顕著であった。属性に違いはなく、搬送時間に差は認めなかった。(結論)平時から小児医療体制が確立しており、COVID-19の感染数も少なかったため、体制は適切に保たれていたが、引き続き今後に対する備えが重要である。(著者抄録)

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  • COVID19パンデミック下における搬送用エアロゾルボックスの検証

    塚原 紘平, 内藤 宏道, 稲葉 基高, 小崎 吉訓, 小原 隆史, 野島 剛, 上田 浩平, 藤崎 宣友, 中尾 篤典, 青井 純子, 藤森 隆史

    日本救急医学会雑誌   31 ( 11 )   1376 - 1376   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 岡山市消防局の救急活動時間におけるCOVID-19の影響

    上田 浩平, 小原 隆史, 野島 剛, 小崎 吉訓, 藤崎 宣友, 塚原 紘平, 山田 太平, 尾迫 貴章, 青景 聡之, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   1368 - 1368   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • NGOによるCOVID-19クラスター対策支援

    稲葉 基高, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   1323 - 1323   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • LIFE(Looking into Intensive care setting on Frailty of Elderly) Study中間報告

    稲葉 基高, 内藤 宏道, 真弓 俊彦, 中尾 篤典, 日本救急医学会高齢者救急特別委員会

    日本救急医学会雑誌   31 ( 11 )   959 - 959   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 飲酒者における外傷の生存率は非飲酒者と同等である 日本外傷データバンクを用いた検討

    野島 剛, 内藤 宏道, 小崎 吉訓, 上原 健敬, 山本 浩継, 藤崎 宣友, 青景 聡之, 塚原 紘平, 山田 太平, 尾迫 貴章, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   1969 - 1969   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

    J-GLOBAL

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  • 水素吸入療法は間質性肺炎遠隔期の呼吸機能を温存する ブレオマイシン処理マウスを用いた研究

    青景 聡之, 平山 隆浩, 池谷 真澄, 大澤 郁朗, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   1644 - 1644   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • COVID-19影響下における救急・集中治療関連医療従事者の心理的健康度

    久保 卓也, 小崎 吉訓, 藤崎 宣友, 青景 聡之, 塚原 紘平, 山田 太平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   1035 - 1035   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • インフルエンザウイルス感染を契機に上気道閉塞、意識障害を呈した甲状腺クリーゼ一例

    佐々並 三紗, 塚原 紘平, 小崎 吉訓, 小原 隆史, 野島 剛, 上田 浩平, 山本 浩継, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   1075 - 1075   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 食事に関する詳細な問診を必要とした壊血病の一例

    小出 恭大, 山田 太平, 小崎 吉訓, 野島 剛, 塚原 紘平, 藤崎 宣友, 尾迫 貴章, 内藤 宏道, 城端 慧, 高岡 諒, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   2105 - 2105   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 論文執筆も点数化を 2019年度救急科専門医試験受験して

    本郷 貴識, 藤原 俊文, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   880 - 880   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • amplitude-integrated EEGが意識障害患者の診断・早期治療に有効であった悪性症候群の1例

    中村 俊介, 内藤 宏道, 野島 剛, 小崎 吉訓, 山本 浩継, 藤崎 宣友, 青景 聡之, 塚原 紘平, 山田 太平, 尾迫 貴章, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   1105 - 1105   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 当院における産科救急の現状

    藤崎 宣友, 山本 浩継, 野島 剛, 小崎 吉訓, 青景 聡之, 塚原 紘平, 山田 太平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   1921 - 1921   2020年11月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 敗血症治療後嚥下障害の発症頻度とリスク因子(Frequency and Risk Factors of Dysphagia Following Sepsis Treatment)

    本郷 貴識, 内藤 宏道, 藤原 俊文, 野崎 哲, 中尾 篤典

    日本救急医学会雑誌   31 ( 11 )   2261 - 2261   2020年11月

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    記述言語:英語   出版者・発行元:(一社)日本救急医学会  

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  • 日本版敗血症診療ガイドライン2020;初期蘇生・ステロイドを知る 敗血症性ショックにおけるステロイド投与のタイミングとは?

    垣花 泰之, 松嶋 麻子, 櫻谷 正明, 廣瀬 智也, 高橋 弘, 田上 隆, 松山 匡, 大下 慎一郎, 下山 哲, 岡本 潤, 山田 浩平, 舩越 拓, 青木 誠, 村田 哲平, 西山 慶, 中森 裕毅, 宮崎 裕也, 内藤 宏道, 安部 隆国, 入野田 崇, 岡 和幸, 角山 泰一朗, 原口 剛, 石川 雅巳, 石丸 剛, 吉廣 尚大, 古川 彩香, 江木 盛時, 小倉 裕司, 西田 修, 田中 裕

    日本集中治療医学会雑誌   27 ( Suppl. )   260 - 260   2020年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 急性肺傷害に対する治療開発 水素吸入療法の炎症・線維化の抑制効果 マウスを用いた検証

    青景 聡之, 池谷 真澄, 瀬谷 瑞樹, 平山 隆浩, 石川 倫子, 内藤 宏道, 大澤 郁朗, 中尾 篤典

    日本集中治療医学会雑誌   27 ( Suppl. )   476 - 476   2020年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 当院の救急集中治療室における、急性腎障害の持続的腎代替療法の導入時期と予後を検討する

    岡田 真澄, 平山 隆浩, 落葉 佑昌, 塚原 紘平, 青景 聡之, 藤崎 宣友, 山田 太平, 内藤 宏道, 中尾 篤典

    日本集中治療医学会雑誌   27 ( Suppl. )   506 - 506   2020年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 一酸化炭素中毒に対し高気圧酸素療法を行った妊婦の一例

    小崎 吉訓, 小出 恭大, 野島 剛, 藤崎 宣友, 青景 聡之, 塚原 紘平, 山田 太平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    中毒研究   33 ( 2 )   162 - 162   2020年9月

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    記述言語:日本語   出版者・発行元:(株)へるす出版  

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  • 静脈-静脈体外式膜型人工肺療法(VV ECMO)ラットモデルの構築

    青景 聡之, 岡田 真澄, 平山 隆浩, 塚原 紘平, 内藤 宏道, 中尾 篤典

    日本集中治療医学会雑誌   27 ( Suppl. )   471 - 471   2020年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • mobile ECMOシステムの構築に向けての現状と問題点 臨床工学技士の立場から

    平山 隆浩, 落葉 佑昌, 堂口 琢磨, 岡田 真澄, 川田 将弘, 青景 聡之, 塚原 紘平, 小崎 吉訓, 内藤 宏道, 中尾 篤典

    日本集中治療医学会雑誌   27 ( Suppl. )   625 - 625   2020年9月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 災害時、都道府県庁には、いつ、だれが行く?西日本豪雨災害を経験した岡山県の取り組み

    山田 太平, 小崎 吉訓, 塚原 紘平, 内藤 宏道, 高田 洋介, 渡邉 暁洋, 大川 恭昌, 加藤 湖月, 中尾 篤典

    Japanese Journal of Disaster Medicine   24 ( 3 )   242 - 242   2019年12月

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    記述言語:日本語   出版者・発行元:(一社)日本災害医学会  

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  • 岡山大学病院における多数傷病者受入れの現状と課題(続報)

    高田 洋介, 渡邉 暁洋, 山田 太平, 小崎 吉訓, 塚原 紘平, 内藤 宏道, 中尾 博之, 中尾 篤典

    Japanese Journal of Disaster Medicine   24 ( 3 )   246 - 246   2019年12月

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    記述言語:日本語   出版者・発行元:(一社)日本災害医学会  

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  • 蘇生中止を考える 高齢者救急集中治療領域におけるevidenceの試み

    稲葉 基高, 内藤 宏道, 中尾 篤典

    蘇生   38 ( 3 )   136 - 136   2019年10月

  • 積極的な画像診断により救命した特発性腸間膜血腫の1例

    山田 太平, 小崎 吉訓, 湯本 哲也, 山本 浩継, 藤崎 宣友, 青景 聡之, 塚原 紘平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   30 ( 9 )   838 - 838   2019年9月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • VV-ECMOを駆使して 他院に収容された超重症呼吸不全をECMOで救命する チーム派遣・ECMO導入・搬送まで担う高度ECMO搬送システムの構築

    青景 聡之, 小崎 吉訓, 塚原 紘平, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   30 ( 9 )   557 - 557   2019年9月

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  • エチレングリコール中毒、「早期介入」が功を奏した一症例

    佐々並 三紗, 山田 太平, 庵谷 紘美, 小崎 吉訓, 湯本 哲也, 山本 浩継, 藤崎 宣友, 塚原 紘平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   30 ( 9 )   639 - 639   2019年9月

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  • 集中治療中に胃壁内気腫症を発症し保存的に治療しえた1例

    庵谷 紘美, 湯本 哲也, 小崎 吉訓, 山本 浩継, 青景 聡之, 藤崎 宣友, 山田 太平, 塚原 紘平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   30 ( 9 )   777 - 777   2019年9月

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  • 開腹止血術と同時に経腹部大動脈アプローチでTEVARを行った1例

    山川 泰明, 小崎 吉訓, 山本 浩継, 藤崎 宣友, 青景 聡之, 塚原 紘平, 山田 太平, 万代 康弘, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   30 ( 9 )   826 - 826   2019年9月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • フレイルは高齢者救急集中治療の予後予測因子となり得るか?

    稲葉 基高, 内藤 宏道, 中尾 篤典

    Medical Science Digest   45 ( 6 )   350 - 353   2019年6月

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    記述言語:日本語   出版者・発行元:(株)ニュー・サイエンス社  

    わが国は世界を牽引する超高齢化社会となり、高齢者の意思の尊重やQuality Of Life(QOL)の重要性が高まっている。しかし、重症の高齢者や時には死期の迫った高齢者が日々搬送されるわが国の救急集中治療の現場で、予後やQOLを評価した研究はほとんどない。我々は救急受診する高齢者の予後予測を行うための指標や予測因子を調査する中でフレイルとの関連に注目し、多施設共同研究を計画した。研究は多施設前向き観察研究。救急室から直接ICU(集中治療室)入室となった65歳以上の高齢者を対象とし、「フレイル」を含む患者背景、治療内容を収集する。6ヵ月後には調査票を郵送することで予後とQOLを明らかにし、予後とQOLに対するフレイルの影響を検証する。6ヵ月生存を主要アウトカム、QOL等を副次アウトカムとする予定で研究が進行中である。フレイルは高齢者救急集中治療の予後予測因子となり得るのか検証し、さらに現場での治療方針の一助となるデータの提示を目指す。(著者抄録)

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  • 外傷性視神経症に対し早期ステロイドパルス療法が奏功したと考えられた1症例

    庵谷紘美, 山田太平, 小崎吉訓, 山川泰明, 飯田淳義, 湯本哲也, 山本浩継, 青景聡之, 藤崎宣友, 塚原紘平, 万代康弘, 尾迫貴章, 内藤宏道, 中尾博之, 中尾篤典

    日本臨床外科学会雑誌   80 ( 3 )   608 - 608   2019年3月

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    記述言語:日本語   出版者・発行元:日本臨床外科学会  

    J-GLOBAL

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  • 西日本豪雨災害における真備地域医療復興プロジェクト支援活動報告

    渡邉 暁洋, 高田 洋介, 山田 太平, 小崎 吉訓, 山川 泰明, 飯田 淳義, 湯本 哲也, 山本 浩継, 青景 聡之, 藤崎 宣友, 塚原 紘平, 万代 康弘, 尾迫 貴章, 内藤 宏道, 中尾 博之, 中尾 篤典

    日本臨床外科学会雑誌   80 ( 3 )   608 - 608   2019年3月

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    記述言語:日本語   出版者・発行元:日本臨床外科学会  

    J-GLOBAL

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  • 日本のキノコ中毒5年間の報告

    小崎 吉訓, 内藤 宏道, 庵谷 紘美, 山川 泰明, 飯田 淳義, 湯本 哲也, 青景 聡之, 藤崎 宣友, 山田 太平, 山本 継, 塚原 紘平, 万代 康弘, 尾迫 貴章, 中尾 博之, 中尾 篤典

    中毒研究   32 ( 1 )   99 - 99   2019年3月

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  • 高度救命救急センターにおける重症患者への蛋白質投与について

    皆尾 望, 藤崎 宣友, 庵谷 紘美, 小崎 吉訓, 山川 泰明, 飯田 淳義, 湯本 哲也, 山本 浩継, 山田 太平, 青景 聡之, 塚原 紘平, 万代 康弘, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本臨床外科学会雑誌   80 ( 3 )   608 - 608   2019年3月

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  • V-Pシャント機能不全を来たした腹腔内髄液仮性嚢胞の一例

    高瀬 了輔, 庵谷 紘美, 井本 良二, 亀田 雅博, 小崎 吉訓, 山川 泰明, 飯田 淳義, 湯本 哲也, 青景 聡之, 藤崎 宣友, 山田 太平, 山本 浩継, 塚原 紘平, 万代 康弘, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本臨床外科学会雑誌   80 ( 3 )   608 - 608   2019年3月

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    記述言語:日本語   出版者・発行元:日本臨床外科学会  

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  • 病院避難におけるDMAT現場指揮所運営の経験から見えてきた諸課題

    飯田 淳義, 山田 太平, 小崎 吉訓, 内藤 宏道, 高田 洋介, 渡邉 暁洋, 大川 恭昌, 三橋 乙矢, 中尾 篤典

    Japanese Journal of Disaster Medicine   23 ( 3 )   363 - 363   2019年2月

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    記述言語:日本語   出版者・発行元:(一社)日本災害医学会  

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  • ECMO中の輸血需要に関連した臨床的特徴と凝固管理

    青景 聡之, 平山 隆浩, 塚原 紘平, 高 寛, 清水 一好, 中川 晃志, 岩崎 達雄, 笠原 真悟, 内藤 宏道, 中尾 篤典

    日本集中治療医学会雑誌   26 ( Suppl. )   [O27 - 6]   2019年2月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 平成30年7月豪雨 水害時の消毒用消石灰散布が及ぼす健康被害

    山田 太平, 小崎 吉訓, 飯田 淳義, 塚原 紘平, 内藤 宏道, 高田 洋介, 渡邉 暁洋, 大川 恭昌, 名倉 弘哲, 三木 真彩菜, 三橋 乙矢, 井上 智美, 加藤 湖月, 中尾 博之, 中尾 篤典

    Japanese Journal of Disaster Medicine   23 ( 3 )   423 - 423   2019年2月

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  • 岡山大学病院における多数傷病者受入れの現状と課題

    高田 洋介, 渡邉 暁洋, 山田 太平, 小崎 吉訓, 塚原 紘平, 内藤 宏道, 中尾 博之, 中尾 篤典

    Japanese Journal of Disaster Medicine   23 ( 3 )   533 - 533   2019年2月

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    記述言語:日本語   出版者・発行元:(一社)日本災害医学会  

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  • 「小児周産期領域における災害対策」 平成30年7月豪雨での岡山県災害時小児周産期リエゾンの活動報告

    塚原 紘平, 小崎 吉訓, 飯田 淳義, 山田 太平, 内藤 宏道, 渡邉 暁洋, 高田 洋介, 中尾 博之, 中尾 篤典

    Japanese Journal of Disaster Medicine   23 ( 3 )   314 - 314   2019年2月

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    記述言語:日本語   出版者・発行元:(一社)日本災害医学会  

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  • 豪雨水害に対する岡山県下の対応と課題

    中尾 博之, 渡邉 暁洋, 高田 洋介, 山田 太平, 内藤 宏道, 飯田 淳義, 小崎 吉訓, 塚原 紘平, 名倉 弘哲, 大川 恭昌, 三橋 乙矢, 三木 真彩菜, 井上 智美, 加藤 湖月, 中尾 篤典

    Japanese Journal of Disaster Medicine   23 ( 3 )   331 - 331   2019年2月

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    記述言語:日本語   出版者・発行元:(一社)日本災害医学会  

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  • 「トリアージの諸問題」 目的に適した災害時トリアージ法の選択 だれがどんなトリアージをいつ行うべきか?

    中尾 博之, 渡邉 暁洋, 山田 太平, 小崎 吉訓, 内藤 宏道, 中尾 篤典, 高田 洋介

    Japanese Journal of Disaster Medicine   23 ( 3 )   290 - 290   2019年2月

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  • 「病院避難において関係機関が認識するべき役割とは〜受援施設と支援機関それぞれの立場から〜」 平成30年7月豪雨におけるまび記念病院の病院避難の経験から DMAT派遣要請基準の考察

    中尾 篤典, 稲葉 基高, 山田 太平, 内藤 宏道, 塚原 紘平, 渡邉 暁洋, 中尾 博之

    Japanese Journal of Disaster Medicine   23 ( 3 )   311 - 311   2019年2月

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    記述言語:日本語   出版者・発行元:(一社)日本災害医学会  

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  • 平成30年7月豪雨災害時の病院避難における現場救護所での活動報告

    三橋 乙矢, 三木 真彩菜, 西尾 拓真, 加藤 湖月, 大川 恭昌, 小崎 吉訓, 飯田 淳義, 塚原 紘平, 山田 太平, 内藤 宏道, 中尾 篤典, 高田 洋介, 渡邉 暁洋, 中尾 博之

    Japanese Journal of Disaster Medicine   23 ( 3 )   363 - 363   2019年2月

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  • 「平成30年7月豪雨」での岡山大学病院の活動・傷病者受け入れ

    内藤 宏道, 小崎 吉訓, 飯田 淳義, 山田 太平, 塚原 紘平, 渡邉 暁洋, 高田 洋介, 中尾 博之, 中尾 篤典

    Japanese Journal of Disaster Medicine   23 ( 3 )   364 - 364   2019年2月

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    記述言語:日本語   出版者・発行元:(一社)日本災害医学会  

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  • 高齢者救急の現状と今後の方策 高齢者救急集中治療に対して「フレイル」が及ぼす影響についての前向き研究

    稲葉 基高, 内藤 宏道, 野崎 哲, 藤原 俊文, 真弓 俊彦, 中尾 篤典

    日本救急医学会雑誌   29 ( 10 )   344 - 344   2018年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 腹部CTからみた薬物過量内服

    浅田 遼, 塚原 紘平, 内藤 宏道, 飯田 淳義, 小崎 吉訓, 山川 泰明, 湯本 哲也, 山本 浩継, 山田 太平, 尾迫 貴章, 中尾 篤典

    日本救急医学会雑誌   29 ( 10 )   444 - 444   2018年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 本人・家族からの申告のなかった農薬中毒例の検討

    有吉 雪乃, 内藤 宏道, 萩岡 信吾, 小崎 吉訓, 飯田 淳義, 湯本 哲也, 山田 太平, 塚原 紘平, 尾迫 貴章, 森本 直樹, 中尾 篤典

    日本救急医学会雑誌   29 ( 10 )   446 - 446   2018年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • アンモニアガス曝露による気管狭窄・肺胞障害を認めた症例

    沢田 孝平, 小崎 吉訓, 山本 浩継, 藤崎 宣友, 青景 聡之, 山田 太平, 塚原 紘平, 万代 康弘, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   29 ( 10 )   437 - 437   2018年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 腹筋運動が誘因となったと思われる特発性腹直筋血腫の1症例

    山田 太平, 小崎 吉訓, 湯本 哲也, 飯田 淳義, 山本 浩継, 藤崎 宣友, 青景 聡之, 塚原 紘平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   29 ( 10 )   553 - 553   2018年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 学会開催日とその前後で外傷患者の死亡率に差はあるか? 日本外傷データバンクより

    湯本 哲也, 内藤 宏道, 庵谷 紘美, 小崎 吉訓, 山川 泰明, 飯田 淳義, 山本 浩継, 山田 太平, 塚原 紘平, 尾迫 貴章, 中尾 篤典

    日本救急医学会雑誌   29 ( 10 )   473 - 473   2018年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 大動脈のCT値を利用した重症外傷患者における新規大量輸血予測ツールの開発

    庵谷 紘美, 湯本 哲也, 小崎 吉訓, 山川 泰明, 飯田 淳義, 山本 浩継, 山田 太平, 塚原 紘平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   29 ( 10 )   473 - 473   2018年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 高度救命救急センターにおけるCRRT膜のlifetimeに関する検討

    岡田 真澄, 平山 隆浩, 末永 健二, 藤原 宏成, 落葉 佑昌, 岩藤 晋, 内藤 宏道, 中尾 篤典, 廣畑 聡

    日本急性血液浄化学会雑誌   9 ( Suppl. )   139 - 139   2018年9月

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    記述言語:日本語   出版者・発行元:(NPO)日本急性血液浄化学会  

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  • Trauma IVRにより救命し得た肺動脈損傷の1症例

    山田 太平, 小崎 吉訓, 山川 泰明, 湯本 哲也, 飯田 淳義, 内藤 宏道, 中尾 篤典

    日本外傷学会雑誌   32 ( 2 )   324 - 324   2018年6月

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    記述言語:日本語   出版者・発行元:(一社)日本外傷学会  

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  • 前頸部熱傷のため気管切開前に同部の植皮を先行させた4例についての検討

    高見 優男, 飯田 淳義, 小崎 吉訓, 山川 泰明, 湯本 哲也, 山田 太平, 山本 浩継, 塚原 紘平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    熱傷   44 ( 2 )   103 - 103   2018年6月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 鈍的体幹部外傷における大腰筋血腫と造影剤の血管外漏出像の意義についての検討

    湯本 哲也, 内藤 宏道, 山川 泰明, 小崎 吉訓, 飯田 淳義, 山田 太平, 中尾 篤典

    日本外傷学会雑誌   32 ( 2 )   284 - 284   2018年6月

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    記述言語:日本語   出版者・発行元:(一社)日本外傷学会  

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  • 当院5年6ヵ月の小児の熱傷における挿管症例の検討

    小崎 吉訓, 山本 浩継, 山川 泰明, 内藤 宏道, 飯田 淳義, 湯本 哲也, 山田 太平, 塚原 紘平, 尾迫 貴章, 中尾 篤紀

    熱傷   44 ( 2 )   104 - 104   2018年6月

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    記述言語:日本語   出版者・発行元:(一社)日本熱傷学会  

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  • 下部尿路損傷を伴う骨盤輪損傷の治療戦略

    山川 泰明, 小崎 吉訓, 湯本 哲也, 飯田 淳義, 山田 太平, 内藤 宏道, 野田 知之, 中尾 篤典

    日本外傷学会雑誌   32 ( 2 )   300 - 300   2018年6月

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    記述言語:日本語   出版者・発行元:(一社)日本外傷学会  

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  • 臨床工学技士の活躍の場の開拓、発展のために ミャンマーとの関わり

    平山 隆浩, 林 久美子, 岩藤 晋, 山川 泰明, 湯本 哲也, 山田 太平, 内藤 宏道, 木股 敬裕, 岡田 茂, 氏家 良人, 中尾 篤典

    日本臨床工学技士会会誌   ( 63 )   149 - 149   2018年4月

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    記述言語:日本語   出版者・発行元:(公社)日本臨床工学技士会  

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  • 院外心停止患者の搬送先病院と予後の検討

    内藤 宏道, 小崎 吉訓, 山川 泰明, 飯田 淳義, 湯本 哲也, 山本 浩継, 山田 太平, 塚原 紘平, 尾迫 貴章, 中尾 篤典

    日本集中治療医学会雑誌   25 ( Suppl. )   [O85 - 2]   2018年2月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 成人熱傷患者の生命予後および合併症と投与カロリーの関連性の検討

    妹尾春佳, 飯田淳義, 湯本哲也, 山本浩継, 青景聡之, 藤崎宣友, 山田太平, 塚原紘平, 尾迫貴章, 内藤宏道, 中尾篤典

    日本救急医学会雑誌   29 ( 10 )   2018年

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  • Cushing'S Sign and Higher Shock Index Are Predictors of the Life-threatening Pediatric Traumatic Brain Injury

    Tetsuya Yumoto, Hiromichi Naito, Hiroki Maeyama, Yoshinori Kosaki, Kohei Tsukahara, Atsunori Nakao

    CIRCULATION   136   2017年11月

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    記述言語:英語   掲載種別:研究発表ペーパー・要旨(国際会議)   出版者・発行元:LIPPINCOTT WILLIAMS & WILKINS  

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  • Occult Sources of Bleeding in Blunt Trauma: A Narrative Review

    Tetsuya Yumoto, Yoshinori Kosaki, Yasuaki Yamakawa, Atsuyoshi Iida, Hirotsugu Yamamoto, Taihei Yamada, Kohei Tsukahara, Hiromichi Naito, Takaaki Osako, Atsunori Nakao

    ACTA MEDICA OKAYAMA   71 ( 5 )   363 - 368   2017年10月

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    記述言語:英語   掲載種別:書評論文,書評,文献紹介等   出版者・発行元:OKAYAMA UNIV MED SCHOOL  

    Worldwide, hemorrhagic shock in major trauma remains a major potentially preventable cause of death. Controlling bleeding and subsequent coagulopathy is a big challenge. Immediate assessment of unidentified bleeding sources is essential in blunt trauma patients with hemorrhagic shock. Chest/pelvic X-ray in conjunction with ultrasonography have been established classically as initial diagnostic imaging modalities to identify the major sources of internal bleeding including intra-thoracic, intra-abdominal, or retroperitoneal hemorrhage related to pelvic fracture. Massive soft tissue injury, regardless of whether isolated or associated with multiple injuries, occasionally causes extensive hemorrhage and acute traumatic coagulopathy. Specific types of injuries, including soft tissue injury or retroperitoneal hemorrhage unrelated to pelvic fracture, can potentially be overlooked or be considered "occult" causes of bleeding because classical diagnostic imaging often cannot exclude such injuries. The purpose of this narrative review article is to describe "occult" or unusual sources of bleeding associated with blunt trauma.

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  • 確定診断に時間を要したStanford A型急性大動脈解離患者の特徴

    華房 宏成, 内藤 宏道, 小崎 吉訓, 塚原 紘平, 尾迫 貴章, 溝上 良一, 川西 進, 萩岡 信吾, 繁光 薫, 中尾 篤典, 森本 直樹

    日本救急医学会雑誌   28 ( 9 )   512 - 512   2017年9月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 救急医として地域、社会全体でリーダーになるということ(To be a regional and global leader as an emergency physician)

    湯本 哲也, 小崎 吉訓, 山川 泰明, 飯田 淳義, 山本 浩継, 山田 太平, 塚原 紘平, 内藤 宏道, 尾迫 貴章, 中尾 篤典

    日本救急医学会雑誌   28 ( 9 )   471 - 471   2017年9月

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  • 指切創処置時における私の工夫

    山川 泰明, 小崎 吉訓, 山本 浩継, 飯田 淳義, 湯本 哲也, 山田 太平, 塚原 紘平, 尾迫 貴章, 内藤 宏道, 中尾 篤典

    日本救急医学会雑誌   28 ( 9 )   502 - 502   2017年9月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • クモ膜下出血術後、スパイナルドレナージの合併症として、血腫による急性閉塞性水頭症を発症した1例

    内藤 宏道, 山川 泰明, 塚原 紘平, 湯本 哲也, 飯田 淳義, 小崎 吉訓, 山本 浩継, 山田 太平, 尾迫 貴章, 中尾 篤典

    日本救急医学会雑誌   28 ( 9 )   625 - 625   2017年9月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • マムシ咬傷における入院期間にかかわる因子の検討

    小崎 吉訓, 内藤 宏道, 山田 太平, 塚原 紘平, 尾迫 貴章, 溝上 良一, 川西 進, 萩岡 信吾, 繁光 薫, 中尾 篤典, 森本 直樹

    日本救急医学会雑誌   28 ( 9 )   726 - 726   2017年9月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 重度呼吸性アシドーシスを合併したPanayiotopoulos syndrome(Panayiotopoulos syndrome associated with severe respiratory acidosis)

    西野 貴大, 飯田 淳義, 塚原 紘平, 内藤 宏道, 山田 太平, 湯本 哲也, 尾迫 貴章, 小崎 吉訓, 山本 浩継, 山川 泰明, 中尾 篤典

    日本救急医学会雑誌   28 ( 9 )   518 - 518   2017年9月

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    記述言語:英語   出版者・発行元:(一社)日本救急医学会  

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  • 過酸化水素摂取後の門脈内ガスに対する高圧酸素療法による治療の成功(Portal venous gas following ingestion of hydrogen peroxide successfully treated with hyperbaric oxygen therapy)

    高尾 賢一朗, 内藤 宏道, 湯本 哲也, 小崎 吉訓, 飯田 淳義, 塚原 紘平, 山本 浩継, 山川 泰明, 山田 太平, 尾迫 貴章, 中尾 篤典

    日本救急医学会雑誌   28 ( 9 )   526 - 526   2017年9月

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    記述言語:英語   出版者・発行元:(一社)日本救急医学会  

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  • 病棟薬剤業務実施加算 岡山大学病院高度救命救急センターにおける病棟薬剤師の役割と展望

    大月 理恵子, 大川 恭昌, 名倉 弘哲, 内藤 宏道, 寺戸 通久, 佐藤 圭路, 鵜川 豊世武, 中尾 篤典

    日本集中治療医学会雑誌   24 ( Suppl. )   SY15 - 2   2017年2月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • AN69ST膜はナファモスタットメシル酸塩のほとんどを吸着する

    平山 隆浩, 大川 恭昌, 鵜川 豊世武, 林 久美子, 野坂 宜之, 湯本 哲也, 塚原 紘平, 内藤 宏道, 佐藤 圭路, 中尾 篤典

    日本集中治療医学会雑誌   24 ( Suppl. )   AW - 2   2017年2月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • A successfully-treated case of penetrating facial trauma.

    Yumoto T, Iida A, Tsukahara K, Naito H, Terado M, Sato K, Date I, Nakao A

    International Journal of Case Reports and Images   8 ( 2 )   120 - 123   2017年

  • 医学部6年次生は二次救命処置のリーダーができるか

    飯田 淳義, 万代 康弘, 芝 直基, 塚原 紘平, 内藤 宏道, 寺戸 通久, 佐藤 圭路, 鵜川 豊世武, 中尾 篤典, 松川 昭博, 那須 保友

    日本救急医学会雑誌   27 ( 9 )   444 - 444   2016年9月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 突然の心肺停止に至った小児前縦隔腫瘍の1例

    香山 尚美, 内藤 宏道, 衛藤 弘城, 福嶋 健志, 黒江 泰利, 野島 宏悦, 杉山 淳一, 梶 俊策, 松本 三明, 森本 直樹

    日本小児救急医学会雑誌   14 ( 1 )   69 - 72   2015年2月

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    記述言語:日本語   出版者・発行元:(一社)日本小児救急医学会  

    突然の心肺停止に至った前縦隔腫瘍の1例を経験した。症例は生来健康な8歳女児。数日前より、乾性咳嗽、呼気時喘鳴、咳き込み嘔吐を主訴に近医受診し、喘息性気管支炎として内服加療を受けていた。某日、夕刻になり、仰臥位での胸部不快感の増悪を訴え、突然の心肺停止状態となり、当院へ救急搬送された。胸部X線写真と胸部超音波検査より左胸腔内の広範な占拠性病変が認められた。胸骨正中切開を行い、腫瘍除去により心拍再開したが、遷延性の意識障害を呈し、入院25日目に死亡した。腫瘍の病理診断は非Hodgkinリンパ腫であり、腫瘍による冠動脈もしくは左房の圧迫が心停止の要因と推測した。喘鳴や仰臥位での呼吸困難の増悪を訴える小児では、縦隔腫瘍も鑑別のひとつとして念頭に置き、胸部X線撮影を考慮すること、また、巨大な縦隔腫瘍では病態の急激な悪化があり得ることを認識しておく必要がある。(著者抄録)

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  • PresepsinとPCTの変動に乖離を認めた侵襲性肺炎球菌感染症の1症例

    大谷 晋吉, 川西 進, 小崎 吉訓, 野島 宏悦, 杉山 淳一, 内藤 宏道, 萩岡 信吾, 森本 直樹

    日本集中治療医学会雑誌   22 ( Suppl. )   [DP44 - 5]   2015年1月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 骨盤骨折症例における画像所見と輸血量の関係

    小崎 吉訓, 内藤 宏道, 野島 宏悦, 大谷 晋吉, 杉山 淳一, 川西 進, 萩岡 信吾, 杉山 雅俊, 森本 直樹

    日本救急医学会雑誌   25 ( 8 )   425 - 425   2014年8月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 当院で経験した外傷性大動脈損傷12例についての後ろ向き調査

    大谷 晋吉, 内藤 宏道, 小崎 吉訓, 川西 進, 森本 直樹

    日本外傷学会雑誌   28 ( 2 )   174 - 174   2014年5月

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    記述言語:日本語   出版者・発行元:(一社)日本外傷学会  

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  • 凝固機能・止血を考慮した輸液・輸血療法 重症外傷における血漿フィブリノーゲン値と輸血量の関係

    内藤 宏道, 大谷 晋吉, 小崎 吉訓, 川西 進, 森本 直樹

    日本外傷学会雑誌   28 ( 2 )   152 - 152   2014年5月

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    記述言語:日本語   出版者・発行元:(一社)日本外傷学会  

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  • 当院における壊死性軟部組織感染症の治療状況と今後の展望

    萩谷 英大, 黒江 泰利, 野島 宏悦, 大谷 晋吉, 杉山 淳一, 内藤 宏道, 川西 進, 萩岡 信吾, 森本 直樹

    津山中央病院医学雑誌   27 ( 1 )   21 - 32   2013年9月

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    記述言語:日本語   出版者・発行元:(一財)津山慈風会津山中央病院  

    壊死性軟部組織感染症(NSTI:Necrotizing Soft Tissue Infection)は致死的疾患であり、救命のためには早急な外科的介入と適切な抗菌薬療法を含めた集学的治療が必要である。当院で経験されたNSTIについて臨床的背景を検討する。方法:「壊死性筋膜炎」「ガス壊疽」「フルニエ壊疽」のキーワードに該当する症例を2001年1月〜2012年5月にかけて後方視的に検索し検討した。結果:対象症例30、男女比21:9、平均年齢65歳(50-83歳)、7日死者率は23.3%(7/30)、28日死亡率は33.3%(10/30)であった。28日生存群(Survivors;S群)と死亡群(Non-survivors;NS群)において、APACHE II scoreはS群15.9、NS群32.4(p<0.00)、入院時SOFA scoreはS群4.3、NS群10.2(p<0.00)であった。24時間以内の外科的介入率は手術不適応例を除いてS群70%(14/20)、NS群71.4%(5/7)(p=0.57)、24時間以内の外科的介入例における手術開始までの平均時間はS群6.1時間、NS群5.4時間(p=0.62)、初回抗菌薬の感受性試験上の有効率は不明例を除いてS群88.9%(16/18)、NS群87.5%(7/8)(p=0.65)であり、いずれも有意差は認めなかった。LRINEC(Laboratory Risk Indicator for Necrotizing Fasciitis)scoreはS群7.3、NS群6.7(p=0.529)で有意差なく、Clinical score predictive of deathはS群4.6、NS群3.6(p=0.027)とむしろS群で有意に高値であった。考察・結語:NSTIは入院時に重症であるほど死に至る可能性が高く、早期の外科的介入、適切な抗菌薬療法を行っても死亡率は改善されなかった。また診断、死亡予測のためのスコアリングも有用ではなかった。NSTIは死亡率が高い疾患であることを十分に認識したうえで、単一所見やスコアリングに頼らず、患者の臨床的背景、リスクファクターなどを考慮して、NSTI疑い症例に対するより早期の診断・治療が全体の予後を改善すると考えられる。(著者抄録)

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  • マムシ咬傷に対する乾燥まむしウマ抗毒素の副作用の調査

    内藤 宏道, 萩岡 信吾, 川西 進, 杉山 淳一, 大谷 晋吉, 野島 宏悦, 黒江 泰利, 小崎 吉訓, 杉山 雅俊, 森本 直樹

    日本救急医学会雑誌   24 ( 8 )   528 - 528   2013年8月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 子宮留膿腫の穿孔による汎発性腹膜炎の1例

    萩谷 英大, 小古山 学, 赤堀 洋一郎, 河原 義文, 内藤 宏道, 萩岡 信吾, 森本 直樹

    日本救急医学会雑誌   24 ( 7 )   431 - 436   2013年7月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

    患者は慢性関節リウマチのため少量のプレドニゾロンとサラゾスルファピリジンを長期内服中の79歳の女性である。右大腿骨骨折に対する骨接合術のため入院中であったが、術後13日目に突然の腹痛が出現した。腹部全体に腹膜刺激症状を認め、腹部CTにて腹腔内に遊離ガスと液体貯留を認めたため消化管穿孔に伴う汎発性腹膜炎が疑われた。しかし同時に内部にガス産生を伴う腫大した子宮を認めたため経腟的ドレナージを施行すると大量の排膿があり、子宮留膿腫の穿孔に伴う汎発性腹膜炎の診断にて開腹手術となった。子宮底に穿孔部位を認め、子宮全摘術および両側付属器切除術を施行し、術後エンドトキシン吸着療法を含めた集学的治療により軽快した。子宮留膿腫は高齢女性にみられる予後良好の慢性疾患である。しかし稀に腹腔内に穿孔し汎発性腹膜炎の原因となり、致死的な疾患となり得ることが報告されている。腹腔内の遊離ガスと液体貯留を呈することが多いため、消化管穿孔の診断のもと開腹手術となり術中に診断されることが多く、術前診断率が低いことが指摘されている。本症例はステロイドと免疫抑制薬を長期併用する慢性関節リウマチ患者に発症した穿孔例であるが、急性腹症として発症する前に明らかな下腹部痛、異常帯下などは認めなかった。腹部CTにて子宮留膿腫の穿孔を疑ったことが、迅速な婦人科紹介、経腟的ドレナージ、適切な術式選択につながり救命できたものと考えられた。一般的に腹腔内の遊離ガスと液体貯留を伴う急性腹症の原因は消化管穿孔と考えられるが、高齢女性においては稀に子宮留膿腫の穿孔があることを救急医は認識しておくべきである。(著者抄録)

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    その他リンク: https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2013&ichushi_jid=J02445&link_issn=&doc_id=20130912260007&doc_link_id=10.3893%2Fjjaam.24.431&url=https%3A%2F%2Fdoi.org%2F10.3893%2Fjjaam.24.431&type=J-STAGE&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00007_3.gif

  • 悪性症候群に合併した重症偽膜性腸炎の一例

    萩谷 英大, 杉山 淳一, 村瀬 智子, 内藤 宏道, 萩岡 信吾, 森本 直樹

    日本集中治療医学会雑誌   20 ( 2 )   281 - 282   2013年4月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

    症例は統合失調症・双極性障害を有する40歳女性で、近医精神科入院中に発熱、筋硬直、発汗を認め、悪性症候群・感染症疑いにてダントロレン、セフトリアキソンを投与されるも改善せず、意識障害、血圧低下が出現し、当院救命救急センター搬送となった。精査の結果、悪性症候群と重症偽腹膜性腸炎を併発したClostridium difficile infection(CDI)と診断した。重症偽腹膜性腸炎は保存的加療とし、悪性症候群に対して経口バンコマイシン、メトロニダゾール投与を開始した。更に血清グロブリン低値に対し免疫グロブリン製剤を投与、DICに対しトロンボモジュリン投与、敗血症性心筋障害に対しドブタミンを投与した。その後全身状態は改善傾向にあったが、搬送15日目に偽膜性腸炎に伴う二次性の直腸腟瘻を発症した。意識障害が遷延したため手術などの積極的治療は行わず、現行治療を継続したが全身状態悪化のため同日死亡した。

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  • 救急救命士における麻疹、風疹、流行性耳下腺炎、水痘帯状疱疹のワクチン接種の重要性

    萩谷 英大, 國米 由美, 黒江 泰利, 野島 宏悦, 大谷 晋吉, 杉山 淳一, 内藤 宏道, 川西 進, 萩岡 信吾, 森本 直樹

    日本臨床救急医学会雑誌   16 ( 2 )   114 - 116   2013年4月

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    記述言語:日本語   出版者・発行元:(一社)日本臨床救急医学会  

    救急医療の最前線で患者対応にあたる救急隊員はさまざまな病原微生物に暴露する可能性が高い。当院に関連する救急救命士116名を対象に、麻疹、風疹、流行性耳下腺炎、水痘帯状疱疹における防御抗体の保有状況を調査した。前3疾患については約3〜5割の者がワクチン接種対象となり、4疾患すべてで非対象となった隊員は22.4%(26名/116名)に過ぎなかった。成人初感染例では重篤な脳炎、肺炎の合併率が高いこと、麻疹、風疹の現在の国内流行状況、救急隊員から搬送患者への感染の可能性などを考慮し、病院内の医療従事者同様に救急隊員も積極的なワクチン接種の対象と考え、そのための体制整備が急務である。(著者抄録)

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    その他リンク: https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2013&ichushi_jid=J03405&link_issn=&doc_id=20130515580013&doc_link_id=%2Fda2jjsem%2F2013%2F001602%2F013%2F0114-0116%26dl%3D0&url=https%3A%2F%2Fwww.medicalonline.jp%2Fjamas.php%3FGoodsID%3D%2Fda2jjsem%2F2013%2F001602%2F013%2F0114-0116%26dl%3D0&type=MedicalOnline&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F00004_2.gif

  • 当院で経験した小児頭部外傷例4年間の後ろ向き調査

    大谷 晋吉, 内藤 宏道, 小崎 吉訓, 川西 進, 森本 直樹

    日本外傷学会雑誌   27 ( 2 )   216 - 216   2013年4月

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    記述言語:日本語   出版者・発行元:(一社)日本外傷学会  

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  • 肝硬変患者に発症したextended spectrum β-lactamase産生大腸菌による大腿部の壊死性軟部組織感染症

    萩谷 英大, 村瀬 智子, 岡原 修司, 岡田 大輔, 杉山 淳一, 内藤 宏道, 萩岡 信吾, 森本 直樹

    日本集中治療医学会雑誌   20 ( 2 )   247 - 252   2013年4月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

    アルコール性肝硬変をもつ78歳男性。搬送2日前に左大腿部を虫に刺され、同部位の紫斑と意識障害のため救急搬送となった。左大腿部の紫斑は拡大傾向であったが、搬送直後と4時間後のCTでは外科的介入の適応にはないと判断された。しかしその後も紫斑、ショック状態が悪化したため搬送9時間後に3度目のCTを施行したところ、筋膜から筋層内にかけて著明らガス所見を認めたため局所のdebridementを施行し、術後も集学的治療を継続したが、搬送から約28時間後に死亡した。血液培養、術中浸出液からCTX-M-8 like遺伝子を有するextended spectrum β-lactamase(ESBL)産生大腸菌を検出したため、ESBL産生大腸菌による左大腿部の壊死性軟部組織感染症と診断した。致死的疾患である壊死性軟部組織感染症の起炎菌として、ESBL産生菌のような高度薬剤耐性菌もありうることに注意する必要がある。(著者抄録)

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  • Pharyngeal Cooling, Brain Temperature Reduction and a Neglect of History Reply

    Yoshimasa Takeda, Hiroshi Hashimoto, Koji Fumoto, Tetsuya Danura, Hiromichi Naito, Naoki Morimoto, Hiroshi Katayama, Soichiro Fushimi, Akihiro Matsukawa, Aiji Ohtsuka, Kiyoshi Morita

    ANESTHESIOLOGY   118 ( 2 )   469 - 470   2013年2月

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)   出版者・発行元:LIPPINCOTT WILLIAMS & WILKINS  

    DOI: 10.1097/ALN.0b013e31827e3c53

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  • 大腿骨転子部骨折術後の子宮留膿腫穿孔による急性腹症の1例

    沖田 駿治, 萩岡 信吾, 黒江 泰利, 野島 宏悦, 萩谷 英大, 大谷 晋吉, 杉山 淳一, 内藤 宏道, 川西 進, 森本 直樹

    日本集中治療医学会雑誌   20 ( Suppl. )   324 - 324   2013年1月

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    記述言語:日本語   出版者・発行元:(一社)日本集中治療医学会  

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  • 内陸地津山で発症した季節外れのVibrio vulnificus感染症

    萩谷英大, 塩田澄子, 三好伸一, 黒江泰利, 野島宏悦, 大谷晋吉, 杉山淳一, 内藤宏道, 川西進, 萩岡信吾, 森本直樹

    岡山医学会雑誌   125 ( 1 )   35 - 39   2013年

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    記述言語:日本語   出版者・発行元:岡山医学会  

    V.vulnificusは世界中の海水中に普遍的に存在し、ヒトには汚染魚介類の生食や創傷への海水の直接曝露によって感染する。本邦では河野らにより長崎県での初感染例が報告されて以来、西日本での発症例が多く、なかでも有明海沿岸からの報告が約40%を占めている。また、海水温度が20℃を超える夏期が好発時期とされている。今回著者等は、10月下旬という非好発時期に、岡山県の内陸地津山で発症したV.vulnificus感染症の死亡例を経験したので、検出されたV.vulnificusについて、抗菌薬感受性、生物型、病原因子遺伝子の検討を行った。結果、抗菌薬感受性は、アンピシリン、シプロフロキサシン、クラリスロマイシン、ゲンタマイシン、ドキシサイクリン、テトラサイクリンに対して良好な感受性を示し、比較対照に用いたL180(ヒトに病原性を示す株)およびPD8(ウナギに病原性を示す株)と同等であった。生物型は1型に分類された。病原因子遺伝子はtype A vvpおよびtype 1 vvhの遺伝子を保有しており、これはヒトのみに病原性を示す菌株(生物型1または3)が持つ型と同じであった。患者は飲酒歴から基礎疾患にアルコール性肝硬変を有していたと推測され、V.vulnificusの感染経路については発症数日前に葬式で賄われた食事から経口感染した可能性が高いと考えられた。

    DOI: 10.4044/joma.125.35

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  • 家族内発生したツキヨタケ中毒例

    内藤 宏道, 萩谷 英大, 萩岡 信吾, 黒江 泰利, 野島 宏悦, 岡原 修司, 岡田 大輔, 杉山 淳一, 森本 直樹

    日本臨床救急医学会雑誌   15 ( 6 )   756 - 759   2012年12月

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    記述言語:日本語   出版者・発行元:(一社)日本臨床救急医学会  

    山で採取したキノコを調理し、家族3人で食べたところ、約2時間後より全員が嘔吐を繰り返し、救急外来を受診した。臨床症状、持参したキノコの形状より、ツキヨタケによる中毒が推定された。輸液による対症療法を行い、嘔吐や倦怠感などの症状は軽快し、翌日、全員が退院となった。ツキヨタケはヒラタケやシイタケと形態が類似し、発育時期や発育場所も共通するため、毒キノコによる中毒のなかでは患者数が多い。通常は対症療法により数日で軽快するが、まれに重症例の報告もあることを念頭におき、注意深く経過観察を行うことが必要である。また、日常より集団発生や夜間発生した場合も含め、対応を検討しておくことが必要と思われる。(著者抄録)

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  • 救急隊員における流行性ウイルス疾患の抗体価保有状況とその重要性

    萩谷 英大, 黒江 泰利, 野島 宏悦, 大谷 晋吉, 杉山 淳一, 内藤 宏道, 川西 進, 萩岡 信吾, 杉山 雅俊, 森本 直樹

    日本救急医学会雑誌   23 ( 10 )   517 - 517   2012年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 当院で気管切開術を施行された症例のうち経皮的気管切開非適応症例の検討

    小崎 吉訓, 内藤 宏道, 黒江 泰利, 野島 宏悦, 萩谷 英大, 大谷 晋吉, 杉山 淳一, 川西 進, 萩岡 信吾, 杉山 雅俊, 森本 直樹

    日本救急医学会雑誌   23 ( 10 )   497 - 497   2012年10月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 当院における劇症型肺炎球菌感染症3症例の検討

    岡原 修司, 黒江 泰利, 萩谷 英大, 野島 宏悦, 岡田 大輔, 住吉 公洋, 杉山 淳一, 内藤 宏道, 萩岡 信吾, 杉山 雅俊, 森本 直樹

    日本救急医学会雑誌   22 ( 8 )   667 - 667   2011年8月

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    記述言語:日本語   出版者・発行元:(一社)日本救急医学会  

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  • 脳低温療法における至適冷却方法 脳低温療法におけるArctic Sunの有用性

    萩岡 信吾, 内藤 宏道, 住吉 公洋, 杉山 淳一, 岡田 大輔, 岡原 修司, 萩谷 英大, 野島 宏悦, 杉山 雅俊, 森本 直樹

    日本脳低温療法学会プログラム・抄録集   14回   66 - 66   2011年7月

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    記述言語:日本語   出版者・発行元:日本脳低温療法・体温管理学会  

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  • 喀血を来したため気道分離を要した外傷性仮性肺嚢胞の三症例

    黒江泰利, 内藤宏道, 野島宏悦, 萩谷英大, 岡原修司, 岡田大輔, 杉山淳一, 住吉公洋, 萩岡信吾, 杉山雅俊, 森本直樹

    日本救急医学会雑誌   22 ( 8 )   2011年

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  • 蘇生時咽頭冷却法の開発と臨床研究

    武田 吉正, 麓 耕二, 大塚 愛二, 白石 建輔, 檀浦 哲也, 内藤 宏道, 萩岡 信吾, 森本 直樹, 森田 潔

    J-ReSS   3   57 - 57   2010年9月

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    記述言語:日本語   出版者・発行元:(一社)日本蘇生協議会  

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  • 蘇生に臨む 咽頭冷却カフの開発と多施設臨床研究

    武田 吉正, 麓 耕二, 大塚 愛二, 白石 建輔, 檀浦 徹也, 内藤 宏道, 萩岡 信吾, 森本 直樹, 森田 潔

    蘇生   28 ( 3 )   155 - 155   2009年10月

  • PMX-DHP導入基準 穿孔性腹膜炎におけるPMX-DHP導入開始時間の検討

    衛藤 弘城, 白石 建輔, 萩岡 信吾, 笠井 慎也, 内藤 宏道, 長江 正晴, 松本 和幸, 福島 達夫, 森本 直樹

    エンドトキシン血症救命治療研究会誌   10 ( 1 )   243 - 244   2006年12月

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    記述言語:日本語   出版者・発行元:(株)自然科学社  

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  • マムシ咬傷48例の検討

    松本 和幸, 内藤 宏道, 久保田 暢人, 谷本 光隆, 長江 正晴, 笠井 慎也, 萩岡 信吾, 白石 建輔, 森本 直樹

    中毒研究   19 ( 2 )   210 - 210   2006年4月

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    記述言語:日本語   出版者・発行元:(株)へるす出版  

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▼全件表示

講演・口頭発表等

  • 広範囲熱傷患者のエネルギー消費の経過

    大塚貴久, 塚原紘平, 内藤宏道, 中尾篤典

    第29回日本熱傷学会中国四国地方会学術集会 

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    開催年月日: 2021年12月11日

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  • 岡山市における重症熱傷患者搬送とコロナウイルス感染症の影響

    上田浩平, 内藤宏道, 塚原紘平, 中尾篤典

    第29回日本熱傷学会中国四国地方会学術集会 

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    開催年月日: 2021年12月11日

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  • 当院EICUにおいて、熱傷患者の熱傷面積が広いほど緑膿菌は検出されるかの検証

    木口隆, 加藤湖月, 野島剛, 小﨑吉訓, 塚原紘平, 藤崎宣友, 内藤宏道, 中尾篤典

    第29回日本熱傷学会中国四国地方会学術集会 

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    開催年月日: 2021年12月11日

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  • 当院高度救命救急センターにおける小児の熱傷と感染に関するまとめ

    小原隆史, 塚原紘平, 野島剛, 上田浩平, 山本浩継, 内藤宏道, 中尾篤典

    第29回日本熱傷学会中国四国地方会学術集会 

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    開催年月日: 2021年12月11日

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  • 日本外傷学会データバンクを用いた熱傷症例の検討

    野島剛, 内藤宏道, 小原隆史, 小﨑吉訓, 上田浩平, 塚原紘平, 中尾篤典

    第29回日本熱傷学会中国四国地方会学術集会 

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    開催年月日: 2021年12月11日

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    塚原紘平, 内藤宏道, 中尾篤典

    第49回日本救急医学会総会 

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    開催年月日: 2021年11月21日 - 2021年11月23日

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  • 蘇生実習における性差教育が与えるインパクト

    谷田貴, 折田沙穂, 塚原紘平, 中村俊介, 久保卓也, 小﨑吉訓, 野島剛, 内藤宏道, 中尾篤典

    第49回日本救急医学会総会 

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    開催年月日: 2021年11月21日 - 2021年11月23日

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  • フレイルが高齢者の救急集中治療の予後に及ぼす影響(最終報告)

    稲葉基高, 内藤宏道, 真弓俊彦, 中尾篤典

    第49回日本救急医学会総会 

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    開催年月日: 2021年11月21日 - 2021年11月23日

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  • COVID-19禍における再利用(洗濯)可能な防水性の医療用ガウンの開発

    内藤宏道, 塚原紘平, 中尾篤典

    第49回日本救急医学会総会 

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    開催年月日: 2021年11月21日 - 2021年11月23日

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  • 巨大地震急性期対応で国際NGOが果たす役割

    稲葉基高, 坂田大三, 内藤宏道, 中尾篤典

    第49回日本救急医学会総会 

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    開催年月日: 2021年11月21日 - 2021年11月23日

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  • 水素吸入は高齢者敗血症の予後を改善させるか? 老齢・LPSモデルマウ スを用いた検証

    青景聡之, 池谷真澄, 藤崎宣友, 大澤郁朗, 内藤宏道, 中尾篤典

    第49回日本救急医学会総会 

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    開催年月日: 2021年11月21日 - 2021年11月23日

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  • 正中弓状靭帯症候群の診断と治療.

    小出恭大, 野島剛, 稲葉基高, 山本浩継, 小崎吉訓, 藤崎宣友, 塚原紘平, 山田太平, 内藤宏道, 池上徹則, 中尾篤典

    第37回日本救急医学会中国四国地方会 

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    開催年月日: 2021年5月28日 - 2021年5月29日

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  • 妊娠・産褥期に体外循環を用いた心肺蘇生(ECPR)と終末期への関わり方.

    小原隆史, 野島剛, 塚原紘平, 青景聡之, 内藤宏道, 中尾篤典

    第37回日本救急医学会中国四国地方会 

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    開催年月日: 2021年5月28日 - 2021年5月29日

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  • DNARオーダーを有する心停止症例の特徴および搬送に関わる救急隊のストレスに関する検討

    田邊綾, 本郷貴識, 稲葉基高, 小崎吉訓, 万代康弘, 山本浩継, 青景聡之, 塚原紘平, 藤崎宣友, 山田太平, 内藤宏道, 中尾篤典

    第37回日本救急医学会中国四国地方会 

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    開催年月日: 2021年5月28日 - 2021年5月29日

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  • IHRR-Jを用いたRRS要請した院内急変患者の自宅復帰の検討

    本郷貴識, 内藤宏道, 野崎哲, 藤原俊文, 中尾篤典

    第37回日本救急医学会中国四国地方会 

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    開催年月日: 2021年5月28日 - 2021年5月29日

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  • 幼児期の睡眠不足は学童期のケガのリスクとなる(21世紀出生児縦断コホート研究)

    小原隆史, 塚原紘平, 山本浩継, 松本尚美, 頼藤貴志, 内藤宏道, 中尾篤典

    第124回日本小児科学会学術集会 

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    開催年月日: 2021年4月16日 - 2021年4月18日

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  • 日本のキノコ中毒5年間の報告

    小?吉訓、内藤宏道、庵谷紘美、山川泰明、飯田淳義、湯本哲也、青景聡之、藤崎宣友、山田太平、山本浩継、塚原紘平、万代康弘、尾迫貴章、中尾博之、中尾篤典

    第30回日本中毒学会中国四国地方会学術集会 

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    開催年月日: 2018年12月8日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 初診時には診断をつけられなかった農薬中毒の2例

    有吉雪乃、内藤宏道、竹居セラ、森本直樹、三浦雅布、中尾篤典

    第30回日本中毒学会中国四国地方会学術集会 

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    開催年月日: 2018年12月8日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 腹筋運動が誘因となったと思われる特発関腹直筋血腫の1症例

    山田太平、小?吉訓、湯本哲也、飯田淳義、山本浩継、藤崎宣友、青景聡之、塚原紘平、尾迫貴章、内藤宏道、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:ポスター発表  

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  • 学会開催日とその前後で外傷患者の死亡率に差はあるのか??日本外傷データバンクより

    湯本哲也、内藤宏道、庵谷紘美、小?吉訓、山川泰明、飯田淳義、山本浩継、山田太平、塚原紘平、尾迫貴章、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 大動脈のCT値を利用した重症外傷患者における新規大量輸血予測ツールの開発

    庵谷紘美、湯本哲也、小?吉訓、山川泰明、飯田淳義、山本浩継、山田太平、塚原紘平、尾迫貴章、内藤宏道、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 救急医療とEnd-of-Life Care?臓器提供認定施設の視点から見えた課題

    尾迫貴章、湯本哲也、塚原紘平、内藤宏道、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • アンモニアガス曝露による気管狭窄・肺胞障害を認めた症例

    沢田孝平、小?吉訓、山本浩継、藤崎宣友、青景聡之、山田太平、塚原紘平、万代康弘、尾迫貴章、内藤宏道、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:ポスター発表  

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  • 腹部CTからみた薬物過量内服

    浅田遼、塚原紘平、内藤宏道、浅田淳義、小?吉訓、山川泰明、湯本哲也、山本浩継、山田太平、尾迫貴章、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 高度救命救急センターにおける歯科医師の救命救急研修の意義

    柴田茜、内藤宏道、塚原紘平、湯本哲也、飯田淳義、山川泰明、尾迫貴章、万代康弘、山田太平、青景聡之、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 本人・家族からの申告のなかった農薬中毒例の検討

    有吉雪乃、内藤宏道、萩岡信吾、小?吉訓、飯田淳義、湯本哲也、山田太平、塚原紘平、尾迫貴章、森本直樹、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 統合失調症との鑑別を要した抗NMDA受容抗体脳炎の一例

    曽田祐民、山本浩継、金聖泰、湯本哲也、塚原紘平、尾迫貴章、内藤宏道、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:ポスター発表  

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  • 成人熱傷患者の生命予後および合併症と投与カロリーの関連性の検討

    妹尾春佳、飯田淳義、湯本哲也、山本浩継、青景聡之、藤崎宣友、山田太平、塚原紘平、尾迫貴章、内藤宏道、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • Acute Agitation as an Initial Manifestation of Neuro-Behcet’s Disease

    Yuki Otsuka,Tetsuya Yumoto,Hiromi Ihoriya,Yoshinori Kosaki,Yasuaki Yamakawa,Atsuyoshi Iida,Hirotsugu Yamamoto,Taihei Yamada,Kohei Tsukahara,Hiromichi Naito,Atsunori Nakao

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:英語   会議種別:口頭発表(一般)  

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  • 齢者救急集中治療に対して「フレイル」が及ぼす影響についての前向き研究

    稲葉基高、内藤宏道、野崎哲、藤原俊文、真弓俊彦、中尾篤典

    第46回日本救急医学会総会・学術集会 

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    開催年月日: 2018年11月19日 - 2018年11月21日

    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(公募)  

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  • Type of Prehospital Airway Management Does Not Affect Chest X-ray Abnormality in Resuscitated Out-of-Hospital Cardiac Arrest Patients.

    Hiromichi Naito1, Atsunori Nakao, Alexandra Weissman, Jonathan Elmer, Christian Martin-Gill, Jon C Rittenberger, Francis X Guyette, Elliott K Gozansky, Glenn S Andrews, Clifton W Callaway.

    American Heart Association Scientific Sessions 2018 

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    開催年月日: 2018年11月10日 - 2018年11月12日

    記述言語:英語   会議種別:ポスター発表  

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  • Return of Spontaneous Circulation is not Affected by Gastric Distension.

    Hiroaki Hanafusa, Hiromichi Naito, Yoshiyuki Ueda, Tetsuya Yumoto, Takashi Yorifuji, Alexandra Weissman, Jon C Rittenberger, Francis X Guyette, Mamoru Fujishima, Makoto Kobayashi, Naoki Morimoto, Atsunori Nakao.

    American Heart Association Scientific Sessions 2018 

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    開催年月日: 2018年11月10日 - 2018年11月12日

    記述言語:英語   会議種別:ポスター発表  

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  • クサフグを自己調理して食中毒となった1症例

    小?吉訓、内藤宏道、庵谷紘美、山川泰明、飯田淳義、湯本哲也、青景聡之、藤崎宣友、山田太平、山本浩継、塚原絋平、万代康弘、尾迫貴章、中尾博之、中尾篤典

    岡山救急医療研究会第20階学術集会 

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    開催年月日: 2018年11月10日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • Issues and Prospects for Medical Education Support to Other Countries Ascertained from the Project for Enhancement of Medical Ecucation(PEME) Dissemination Seminar on Emergency Medicine.

    Taihei Yamada, Takahiro Hirayama, Hiromi Ihoriya, Yoshinori Kosaki, Yasuaki Yamakawa, Tetsuya Yumoto, Atsuyoshi Iida, Kohei Tsukahara, Takaaki Osako, Hiromichi Naito, Atsunori Nakao.

    The 14th Asia Pacific Conference on Disaster Medicine 

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    開催年月日: 2018年10月16日 - 2018年10月18日

    記述言語:英語   会議種別:ポスター発表  

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  • 鈍的体幹部外傷における大腰筋血腫と造影剤の血管外漏出像の意義についての検討

    湯本哲也、内藤宏道、山川泰明、小?吉訓、飯田淳義、山田太平、中尾篤典

    第32回日本外傷学会総会・学術集会 

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    開催年月日: 2018年6月21日 - 2018年6月22日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 下部尿路損傷を伴う骨盤輪損傷の治療戦略

    山川泰明、小?吉訓、湯本哲也、飯田淳義、山田太平、内藤宏道、野田知之、中尾篤典

    第32回日本外傷学会総会・学術集会 

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    開催年月日: 2018年6月21日 - 2018年6月22日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • Trauma IVRにより救命し得た肺動脈損傷の1症例

    山田太平、小?吉訓、山川泰明、湯本哲也、飯田淳義、内藤宏道、中尾篤典

    第32回日本外傷学会総会・学術集会 

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    開催年月日: 2018年6月21日 - 2018年6月22日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • Pediatric Acute Encephalopathy in ICU: Study from JaRPAC Database.

    Kohei Tsukahara, Nobuyuki Nosaka, Knaup Emily, Hirotsugu Yamamoto, Tetsuya Yumoto, Takaaki Osako, Hiromichi Naito, Atsunori Nakao.

    9th Congress of the World Federation of Pediatric Intensive & Critical Care Societies 

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    開催年月日: 2018年6月9日 - 2018年6月13日

    記述言語:英語   会議種別:ポスター発表  

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  • AN69ST membrane sdsorbs a large portion of the nafamostat mesilate and affect the management of anticoagulant therapy.

    Takahiro Hirayama, Satoru Esumi, Soichiro Ushio, Yasumasa Okawa, Nobuyuki Nosaka, Tetsuya Yumoto, Yoshihisa Kitamura, Toshiaki Sendo, Hiromichi Naito, Atsunori Nakao.

    International Conference on Emergency Medicine 2018 

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    開催年月日: 2018年6月6日 - 2018年6月9日

    記述言語:英語   会議種別:ポスター発表  

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  • A Difficult-to-diagnosis Case of Caffeine Intoxication.

    Yukino Ariyoshi, Hiromichi Naito, Taihei Yamada, Sella Takei, Hiroki Maeyama, Atsunori Nakao.

    International Conference on Emergency Medicine 2018 

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    開催年月日: 2018年6月6日 - 2018年6月9日

    記述言語:英語   会議種別:ポスター発表  

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  • A Successfully Treated Case of Criminal Thallium Poisoning.

    Sella Takei, Yukino Ariyoshi, Taihei Yamada, Hiromichi Naito, Hiroki Maeyama, Atsunori Nakao.

    International Conference on Emergency Medicine 2018 

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    開催年月日: 2018年6月6日 - 2018年6月9日

    記述言語:英語   会議種別:ポスター発表  

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  • Pneumoperitoneum with hydrogen-containing carbon dioxide ameliorates bowel inflammation.

    Hirotsugu Yamamoto, Taihei Yamada, Tetsuya Yumoto, Takaaki Osako, Hiromichi Naito, Atsunori Nakao.

    International Conference on Emergency Medicine 2018 

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    開催年月日: 2018年6月6日 - 2018年6月9日

    記述言語:英語   会議種別:ポスター発表  

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  • successfully treated case of cardiac arrest due to septic shock with extracorporeal membrane oxygenation.

    Hiroki Maeyama, Yuki Bansyotani, Daisaku Matsui, Makoto Kobayashi , Atsunori Nakao.

    International Conference on Emergency Medicine 2018 

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    開催年月日: 2018年6月6日 - 2018年6月9日

    記述言語:英語   会議種別:ポスター発表  

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  • Minimally Invasive Repair of Flail Chest and Open Pneumothorax with Bioabsorbable Fixation Device Made from Poly-L-lactic Acid.

    Taihei Yamada, Hiromi Ihoriya, Yoshori Kosaki, Yasuaki Yamakawa, Tetsuya Yumoto, Atsuyoshi Iida, Hirotsugu Yamamoto, Toshiyuki Aokage, Kouhei Tsukahara, Yasuhiro Mandai, Takaaki Osako, Hiromichi Naitou, Atsunori Nakao.

    International Conference on Emergency Medicine 2018 

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    開催年月日: 2018年6月6日 - 2018年6月9日

    記述言語:英語   会議種別:ポスター発表  

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  • 潰瘍を伴うGIST からの大量下血が診断の契機となった神経線維腫症1 型の1 救命例

    田邉綾、飯田淳義、小?吉訓、山川泰明、湯本哲也、山田太平、山本浩継、塚原紘平、万代康弘、尾迫貴章、内藤宏道、中尾 篤典

    第34回日本救急医学会中国四国地方会 

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    開催年月日: 2018年5月11日 - 2018年5月12日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 急性脳症と誤診されたAbusive Head Traumaの1例

    山本浩継、小崎吉訓、山川泰明、飯田淳義、湯本哲也、山田太平、塚原紘平、尾迫貴章、万代康弘、内藤宏道、中尾篤典

    第34回日本救急医学会中国四国地方会 

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    開催年月日: 2018年5月11日 - 2018年5月12日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 右内頸静脈穿刺による脱血での体外膜型肺を併用した心肺蘇生:脱血カニューレに関して

    安原大貴、内藤宏道、野島宏悦、小?吉訓、山川泰明、湯本哲也、山本浩継、山田太平、塚原紘平、尾迫貴章、万代康弘、中尾篤典

    第34回日本救急医学会中国四国地方会 

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    開催年月日: 2018年5月11日 - 2018年5月12日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • ICUに入室した小児急性脳症の疫学的特徴:多施設共同データベース(JaRPAC)をもとに

    塚原紘平,山本浩継,野坂宜之,クナウプ絵美里,尾迫貴章,内藤宏道,中尾篤典

    第45回日本集中治療医学会学術集会 

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    開催年月日: 2018年2月21日 - 2018年2月23日

    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(公募)  

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  • 院外心停止患者の搬送先病院と予後の検討

    内藤宏道,小?吉訓,山川泰明,飯田淳義,湯本哲也,山本浩継,山田太平,塚原紘平,尾迫貴章,中尾篤典

    第45回日本集中治療医学会学術集会 

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    開催年月日: 2018年2月21日 - 2018年2月23日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 腰動脈損傷を伴う多発脊椎骨折の3例.

    山川泰明、小?吉訓、山本浩継、飯田淳義、湯本哲也、山田太平、塚原絋平、尾迫貴章、内藤宏道、野田知之、尾崎敏文、中尾篤典.

    第23回救急整形外傷シンポジウム 

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    開催年月日: 2017年11月23日 - 2017年11月25日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • Two Case of Pulmonary Artery Injury Successfully Rescued by Trauma Interventional Radiology.

    Yamada T, Ihoriya H, Inoue K, Kosaki Y, Yamamoto H, Yumoto T, Iida A, Tsukahara K, Osako T, Naito H, Nakao A.

    The 9th Asian Conference On Emergency Medicine 

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    開催年月日: 2017年11月22日 - 2017年11月25日

    記述言語:英語   会議種別:ポスター発表  

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  • A Case of Effective Early Steroid Pulse Therapy for Traumatic Optic Neuropathy.

    Ihoriya H, Inoue K, Kosaki Y, Yamamoto H, Yumoto T, Iida A, Yamada T, Tsukahara K, Osako T, Naito H, Nakao A.

    The 9th Asian Conference On Emergency Medicine 

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    開催年月日: 2017年11月22日 - 2017年11月25日

    記述言語:英語   会議種別:ポスター発表  

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  • In-Flight-Intubation Shortens the Transportation Time in Helicopter Emergency Medical Service System.

    Maeyama H,Naito H,Francis X Guyette,Bansyatani Y,Matsui D,Yumoto T,Nakao A,Kobayashi M.

    The 9th Asian Conference On Emergency Medicine 

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    開催年月日: 2017年11月22日 - 2017年11月25日

    記述言語:英語   会議種別:ポスター発表  

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  • Pneumoperitoneum with hydorogen-containing carbon dioxide ameliorates bowel inflammation.

    Nakao A, Yumoto T, Yamada T, Naito H.

    The 9th Asian Conference On Emergency Medicine 

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    開催年月日: 2017年11月22日 - 2017年11月25日

    記述言語:英語   会議種別:口頭発表(一般)  

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  • Cushing’s Sign and Higher Shock Index Are Predictors of the Life-threatening Pediatric Traumatic Brain Injury.

    Yumoto T, Naito H, Maeyama H, Kosaki Y, Tsukahara K, Nakao A.

    American Heart Association Scientific Sessions 2017 

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    開催年月日: 2017年11月11日 - 2017年11月15日

    記述言語:英語   会議種別:口頭発表(一般)  

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  • Two different medical direction for airway management in a single city did not affect outcome of out-of-hospital cardiac arrest patients.

    Naito H, Yumoto T, Maeyama H, Kosaki Y, Yamamoto H, Yamakawa Y, Iida A, Yamada T, Tsukahara K, Osako T, Callaway CW, Okazaki Y, Mikane T, Nakao A.

    American Heart Association Scientific Sessions 2017 

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    開催年月日: 2017年11月11日 - 2017年11月15日

    記述言語:英語   会議種別:口頭発表(一般)  

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  • 当院高度救命救急センターにおける歯科連携システム.

    松井裕一、内藤宏道、塚原絋平、飯田淳義、湯本哲也、山川泰明、吉田祥子、國定勇希、佐々木朗、飯田征二、中尾篤典.

    第45回日本救急医学会総会・学術集会 

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    開催年月日: 2017年10月24日 - 2017年10月26日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 指切創処置時における私の工夫.

    山川泰明, 小?吉訓, 山本浩継, 飯田淳義, 湯本哲也, 山田太平, 塚原絋平, 尾迫貴章, 内藤宏道, 中尾篤典.

    第45回日本救急医学会総会・学術集会 

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    開催年月日: 2017年10月24日 - 2017年10月26日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • クモ膜下出血術後、スパイナルドレナージの合併症として、血腫による急性閉塞性水頭症を発症した1例.

    内藤宏道、山川泰明、塚原絋平、湯本哲也、飯田淳義、小?吉訓、山本浩継、山田太平、尾迫貴章、中尾篤典.

    第45回日本救急医学会総会・学術集会 

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    開催年月日: 2017年10月24日 - 2017年10月26日

    記述言語:日本語   会議種別:ポスター発表  

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  • To be a regional and global leader as an emergency physician.

    湯本哲也、小?吉訓、山川泰明、飯田淳義、山本浩継、山田太平、塚原絋平、内藤宏道、尾迫貴章、中尾篤典.

    第45回日本救急医学会総会・学術集会 

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    開催年月日: 2017年10月24日 - 2017年10月26日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • Portal venous gas following ingestion of hydrogen peroxide successfully treated with hyperbaric oxygen therapy.

    高尾賢一朗、内藤宏道、湯本哲也、小?吉訓、飯田淳義、塚原絋平、山本浩継、山川泰明、山田太平、尾迫貴章、中尾篤典.

    第45回日本救急医学会総会・学術集会 

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    開催年月日: 2017年10月24日 - 2017年10月26日

    記述言語:英語   会議種別:口頭発表(一般)  

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  • 確定診断に時間を要したStanford A型急性大動脈解離患者の特徴.

    華房宏成、内藤宏道、小?吉訓、塚原絋平、尾迫貴章、溝上良一、川西進、萩岡信吾、繁光薫、中尾篤典、森本直樹.

    第45回日本救急医学会総会・学術集会 

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    開催年月日: 2017年10月24日 - 2017年10月26日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • Panayiotopoulos syndrome associated with severe respiratory acidosis.

    西野貴大、飯田淳義、塚原絋平、内藤宏道、山田太平、湯本哲也、尾迫貴章、小?吉訓、山本浩継、山川泰明、中尾篤典.

    第45回日本救急医学会総会・学術集会 

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    開催年月日: 2017年10月24日 - 2017年10月26日

    記述言語:英語   会議種別:口頭発表(一般)  

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  • マムシ咬傷における入院期間にかかわる因子の検討.

    小?吉訓、内藤宏道、山田太平、塚原絋平、尾迫貴章、溝上良一、川西進、萩岡信吾、繁光薫、中尾篤典、森本直樹.

    第45回日本救急医学会総会・学術集会 

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    開催年月日: 2017年10月24日 - 2017年10月26日

    記述言語:日本語   会議種別:ポスター発表  

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  • 人工呼吸器の流量波形による経肺圧の推測は可能か.

    林久美子、平山隆浩、塚原紘平、内藤宏道、湯本哲也、飯田淳義、山川泰明、寺戸通久、佐藤圭路、鵜川豊世武、中尾篤典.

    第39回日本呼吸療法医学会学術集会 

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    開催年月日: 2017年7月15日 - 2017年7月16日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 遠位骨片の粉砕を伴う鎖骨遠位端骨折の治療経験.

    山川泰明、小松原将、野田知之、湯本哲也、飯田淳義、塚原絋平、内藤宏道、中尾篤典、尾崎敏文.

    第43回日本骨折治療学会 

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    開催年月日: 2017年7月7日 - 2017年7月8日

    記述言語:日本語   会議種別:ポスター発表  

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  • 骨盤骨折に伴うVTEの発生率.

    山川泰明、小松原将、野田知之、湯本哲也、飯田淳義、塚原絋平、内藤宏道、中尾篤典、尾崎敏文.

    第31回日本外傷学会総会・学術集会 

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    開催年月日: 2017年6月1日 - 2017年6月2日

    記述言語:日本語   会議種別:ポスター発表  

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  • 当院における腎損傷の治療成績.

    松尾聡子、山川泰明、湯本哲也、飯田淳義、塚原紘平、内藤宏道、 中尾篤典.

    第31回日本外傷学会総会・学術集会 

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    開催年月日: 2017年6月1日 - 2017年6月2日

    記述言語:日本語   会議種別:ポスター発表  

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  • 社会復帰となった11階からの墜落外傷.

    松尾聡子、山川泰明、湯本哲也、飯田淳義、塚原紘平、内藤宏道、 中尾篤典.

    第31回日本外傷学会総会・学術集会 

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    開催年月日: 2017年6月1日 - 2017年6月2日

    記述言語:日本語   会議種別:ポスター発表  

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  • 高度救命救急センターにおける小児外傷診療、小児体制整備の検証.

    塚原絋平、飯田淳義、湯本哲也、山川泰明、内藤宏道、寺戸通久、佐藤圭路、鵜川豊世武、中尾篤典.

    第20回日本臨床救急医学会総会・学術集会 

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    開催年月日: 2017年5月26日 - 2017年5月27日

    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(指名)  

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  • 不適切なペット飼育方法が要因と考えられたパスツレラ肺炎の1例.

    安藤明美、山川泰明、飯田淳義、湯本哲也、塚原紘平、内藤宏道、寺戸通久、佐藤圭路、鵜川豊世武、中尾篤典.

    第8回日本プライマリ・ケア連合学会学術大会 

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    開催年月日: 2017年5月13日 - 2017年5月14日

    記述言語:日本語   会議種別:ポスター発表  

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  • Venous thromboembolism in major trauma patients:a single center descriptive study.

    Yumoto T, Naito H, Yamakawa Y, Iida A, Nosaka N, Knaup E, Tsukahara K, Terado M, Sato K, Ugawa T, Nakao A.

    第44回日本集中治療医学会学術集会 

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    開催年月日: 2017年3月9日 - 2017年3月11日

    記述言語:英語   会議種別:口頭発表(一般)  

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  • 岡山大学病院高度救命救急センターにおける高気圧酸素療法(HBO)の現状と課題.

    佐藤圭路、湯本哲也、飯田淳義、塚原絋平、野坂宜之、クナウプ絵美里、内藤宏道、寺戸通久、鵜川豊世武、中尾篤典.

    第44回日本集中治療医学会学術集会 

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    開催年月日: 2017年3月9日 - 2017年3月11日

    記述言語:日本語   会議種別:ポスター発表  

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  • AN69ST膜はナファモスタットメシル酸塩のほとんどを吸着する.

    平山隆浩、大川恭昌、鵜川豊世武、林久美子、野坂宜之、湯本哲也、塚原紘平、内藤宏道、佐藤圭路、中尾篤典.

    第44回日本集中治療医学会学術集会 

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    開催年月日: 2017年3月9日 - 2017年3月11日

    記述言語:日本語   会議種別:口頭発表(一般)  

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  • 岡山大学病院高度救命救急センターにおける病棟薬剤師の役割と展望.

    大月理恵子、大川恭昌、名倉弘哲、内藤宏道、寺戸通久、鵜川豊世武、中尾篤典.

    第44回日本集中治療医学会学術集会 

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    開催年月日: 2017年3月9日 - 2017年3月11日

    記述言語:日本語   会議種別:シンポジウム・ワークショップ パネル(指名)  

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  • 医学科6年次生は二次救命処置のリーダーができるか.

    飯田淳義、万代康弘、芝直基、塚原絋平、内藤宏道、寺戸通久、佐藤圭路、鵜川豊世武、中尾篤典、松川昭博、那須保友.

    第44回日本救急医学会総会学術集会 

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    開催年月日: 2016年11月17日 - 2016年11月19日

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:東京  

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  • 病院前心停止患者に対する気道確保器具(気管挿管/声門上気道確保器具)の胸部レントゲン浸潤影への影響.

    内藤宏道.

    第44回日本救急医学会総会学術集会 

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    開催年月日: 2016年11月17日 - 2016年11月19日

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:東京  

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  • Ambiguity of the Self-Report Description of Cormack-Lehane View Grading in the Prehospital Setting.

    Naito H .

    2016 American Heart Association Resuscitation Science Symposium 

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    開催年月日: 2016年11月11日 - 2016年11月14日

    記述言語:英語   会議種別:口頭発表(一般)  

    開催地:New Orleans,USA  

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  • Interruptions of views are associated with failed endotracheal intubation and shallow laryngoscopic blade position is associated with longer attempt time in the prehospital settings

    Naito H,

    Best Abstract Award in Trauma Resuscitation Science 

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    開催年月日: 2015年11月7日 - 2015年11月9日

    記述言語:英語   会議種別:口頭発表(一般)  

    開催地:アメリカ合衆国  

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  • 重症外傷における血漿フィブリノーゲン値と輸血量の関係

    内藤宏道

    第28回日本外傷学会総会 

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    開催年月日: 2014年6月25日 - 2014年6月26日

    記述言語:日本語   会議種別:口頭発表(一般)  

    開催地:東京  

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受賞

  • American Heart Association Resuscitation Science Symposium 2015, Best Abstract Award in Trauma Resuscitation Science

    2015年11月  

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  • 第10回日本神経麻酔集中治療学会学術賞

    2014年  

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共同研究・競争的資金等の研究

  • 慢性外傷性脳症モデル確立と経動脈的幹細胞移植:タウ蛋白と遺伝子発現の変化に迫る

    研究課題/領域番号:22K09207  2022年04月 - 2025年03月

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    安原 隆雄, 内藤 宏道, 道上 宏之, 菱川 朋人, 田尻 直輝, 佐々木 達也, 佐々田 晋

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    配分額:4160000円 ( 直接経費:3200000円 、 間接経費:960000円 )

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  • 心停止後症候群に対する33℃と35℃の目標温度管理の神経学的予後に関する比較

    2021年 - 2025年

    日本学術振興会  科学研究費助成事業 基盤研究(C) 

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    担当区分:研究代表者 

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  • 高齢者の救急・集中治療に対してフレイルが及ぼす影響:多施設共同研究

    2018年 - 2020年

    日本学術振興会  科学研究費助成事業 基盤研究(C) 

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    担当区分:研究代表者 

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担当授業科目

  • 実践救命救急・災害医学(演習・実習) (2023年度) 特別  - その他

  • 実践救命救急・災害医学(講義・演習) (2023年度) 特別  - その他

  • 救命救急・災害医学Ⅰ(演習・実習) (2023年度) 特別  - その他

  • 救命救急・災害医学Ⅰ(講義・演習) (2023年度) 特別  - その他

  • 救命救急・災害医学Ⅱ(演習・実習) (2023年度) 特別  - その他

  • 救命救急・災害医学Ⅱ(講義・演習) (2023年度) 特別  - その他

  • 救命救急・災害医学実習 (2023年度) 特別  - その他

  • 救命救急・災害医学演習 (2023年度) 特別  - その他

  • 実践救命救急・災害医学(演習・実習) (2022年度) 特別  - その他

  • 実践救命救急・災害医学(講義・演習) (2022年度) 特別  - その他

  • 救命救急・災害医学Ⅰ(演習・実習) (2022年度) 特別  - その他

  • 救命救急・災害医学Ⅰ(講義・演習) (2022年度) 特別  - その他

  • 救命救急・災害医学Ⅱ(演習・実習) (2022年度) 特別  - その他

  • 救命救急・災害医学Ⅱ(講義・演習) (2022年度) 特別  - その他

  • 救命救急・災害医学Ⅰ(演習・実習) (2021年度) 特別  - その他

  • 救命救急・災害医学Ⅰ(講義・演習) (2021年度) 特別  - その他

  • 救命救急・災害医学Ⅱ(演習・実習) (2021年度) 特別  - その他

  • 救命救急・災害医学Ⅱ(講義・演習) (2021年度) 特別  - その他

  • 救急医学I(演習・実習) (2021年度) 特別  - その他

  • 救急医学I(講義・演習) (2021年度) 特別  - その他

  • 救急医学II(演習・実習) (2021年度) 特別  - その他

  • 救急医学II(講義・演習) (2021年度) 特別  - その他

  • 実践救命救急・災害医学(演習・実習) (2020年度) 特別  - その他

  • 実践救命救急・災害医学(講義・演習) (2020年度) 特別  - その他

  • 救命救急・災害医学Ⅰ(演習・実習) (2020年度) 特別  - その他

  • 救命救急・災害医学Ⅰ(講義・演習) (2020年度) 特別  - その他

  • 救命救急・災害医学Ⅱ(演習・実習) (2020年度) 特別  - その他

  • 救命救急・災害医学Ⅱ(講義・演習) (2020年度) 特別  - その他

  • 救急医学I(演習・実習) (2020年度) 特別  - その他

  • 救急医学I(講義・演習) (2020年度) 特別  - その他

  • 救急医学II(演習・実習) (2020年度) 特別  - その他

  • 救急医学II(講義・演習) (2020年度) 特別  - その他

▼全件表示

 

メディア報道

  • 新型コロナの診療医が岡山大学で講演会 現場の状況や課題語る インターネットメディア

    NHK NEWS WEB  岡山 NEWS WEB  2022年12月

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    執筆者:本人以外 

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