Faculty Profiles - Makimoto Go

Papers - Makimoto Go

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PET-CTにて縦隔・肺門リンパ節転移陽性の肺癌症例における超音波気管支鏡ガイド下針生検の有用性

南大輔, 瀧川奈義夫, 小田尚廣, 槇本剛, 二宮貴一朗, 豊田容輔, 肥後寿夫, 久保寿夫, 大橋圭明, 佐藤晃子, 堀田勝幸, 宮原信明, 金廣有彦, 田端雅弘, 谷本光音, 木浦勝行

気管支学 37 ( 3 ) 345 - 345 2015.5

気管支鏡検査における迅速細胞診の進歩と問題点 BIOEVALUATORを用いた迅速細胞診断を併用した超音波気管支鏡ガイド下針生検の有用性

南大輔, 瀧川奈義夫, 槇本剛, 小田尚廣, 豊田容輔, 二宮貴一朗, 肥後寿夫, 久保寿夫, 大橋圭明, 佐藤晃子, 堀田勝幸, 宮原信明, 金廣有彦, 田端雅弘, 谷本光音, 木浦勝行

気管支学 37 ( Suppl. ) S151 - S151 2015.5

PET-CTにて縦隔、肺門リンパ節転移偽陽性の肺癌症例における超音波気管支鏡ガイド下針生検の有用性

気管支学 37 ( Suppl. ) S193 - S193 2015.5

ガイドシース併用気管支腔内超音波断層法による経気管支肺生検で確定診断された悪性リンパ腫の2例

肥後寿夫, 南大輔, 小田尚廣, 豊田容輔, 二宮貴一朗, 槇本剛, 谷口暁彦, 久保寿夫, 大橋圭明, 佐藤晃子, 堀田勝幸, 宮原信明, 田端雅弘, 金廣有彦, 谷本光音, 木浦勝行

気管支学 37 ( Suppl. ) S287 - S287 2015.5

腎移植後の免疫抑制療法に合併した肺クリプトコッカス症の診断にEBUS-GSが有用であった1例

槇本剛, 南大輔, 宮原信明, 久保寿夫, 大橋圭明, 佐藤晃子, 堀田勝幸, 金廣有彦, 田端雅弘, 谷本光音, 木浦勝行

気管支学 37 ( 3 ) 345 - 345 2015.5

経気管支肺生検にて悪性リンパ腫と確定診断された4例

小田尚廣, 南大輔, 瀧川奈義夫, 槙本剛, 二宮貴一郎, 豊田容輔, 肥後寿夫, 久保寿夫, 大橋圭明, 佐藤晃子, 堀田勝幸, 宮原信明, 金廣有彦, 田端雅弘, 谷本光音, 木浦勝行

気管支学 37 ( 3 ) 350 - 350 2015.5

BIOEVALUATORを用いた迅速細胞診断を併用したEBUS-TBNAの有用性

槇本剛, 南大輔, 瀧川奈義夫, 二宮貴一朗, 小田尚廣, 豊田容輔, 肥後寿夫, 久保寿夫, 大橋圭明, 佐藤晃子, 堀田勝幸, 宮原信明, 金廣有彦, 田端雅弘, 谷本光音, 木浦勝行

日本呼吸器学会誌 4 ( 増刊 ) 216 - 216 2015.3

ガイドシース併用気管支腔内超音波断層法の肺癌診断への導入効果

南大輔, 瀧川奈義夫, 二宮貴一朗, 小田尚廣, 豊田容輔, 槙本剛, 肥後寿夫, 久保寿夫, 大橋圭明, 佐藤晃子, 堀田勝幸, 宮原信明, 金廣有彦, 田端雅弘, 谷本光音, 木浦勝行

肺癌 54 ( 5 ) 534 - 534 2014.10

ACTH産生胸腺神経内分泌腫瘍に合併したニューモシスチス肺炎の1例

枝木久典, 南大輔, 二宮貴一朗, 小田尚廣, 豊田容輔, 槇本剛, 肥後寿夫, 久保寿夫, 大橋圭明, 佐藤晃子, 堀田勝幸, 宮原信明, 金廣有彦, 田端雅弘, 谷本光音, 木浦勝行, 小松原基志, 稲垣兼一

肺癌 54 ( 4 ) 260 - 260 2014.8

Phrenic nerve paralysis as the initial presentation in pleural sarcomatoid mesothelioma. International journal

Go Makimoto, Keiichi Fujiwara, Nobukazu Fujimoto, Ichiro Yamadori, Toshio Sato, Takumi Kishimoto

Case reports in oncology 7 ( 2 ) 389 - 92 2014.5

Language：English

A 74-year-old man was referred to our hospital because of persistent cough. A chest radiograph revealed an elevation of the right diaphragm. Computed tomography (CT) images revealed a small nodule localized on the right mediastinum. Five months later, the nodule had grown and was diagnosed as malignant pleural mesothelioma (MPM) by a CT-guided needle biopsy. The patient underwent combined chemotherapy, but the disease progressed rapidly and he passed away. On autopsy, microscopic findings and immunohistological examinations supported the diagnosis of sarcomatoid mesothelioma. Therefore, we diagnosed this rare case as localized sarcomatoid MPM showing phrenic nerve paralysis as an initial presentation.

DOI： 10.1159/000363760

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nab-Paclitaxel in Combination with Carboplatin for a Previously Treated Thymic Carcinoma. International journal

Go Makimoto, Keiichi Fujiwara, Hiromi Watanabe, Nobuhisa Kameyama, Mizuho Matsushita, Kammei Rai, Ken Sato, Toshiro Yonei, Toshio Sato, Takuo Shibayama

Case reports in oncology 7 ( 1 ) 14 - 7 2014.1

Language：English

We present the case of a 40-year-old man with previously treated thymic carcinoma, complaining of gradually worsening back pain. Computed tomography scans of the chest showed multiple pleural disseminated nodules with a pleural effusion in the right thorax. The patient was treated with carboplatin on day 1 plus nab-paclitaxel on day 1 and 8 in cycles repeated every 4 weeks. Objective tumor shrinkage was observed after 4 cycles of this regimen. In addition, the elevated serum cytokeratin 19 fragment level decreased, and the patient's back pain was relieved without any analgesics. Although he experienced grade 4 neutropenia and granulocyte colony-stimulating factor (G-CSF) injection, the severity of thrombocytopenia and nonhematological toxicities such as reversible neuropathy did not exceed grade 1 during the treatment. To our knowledge, this is the first report to demonstrate the efficacy of combination chemotherapy consisting of carboplatin and nab-paclitaxel against thymic carcinoma. This case report suggests that nab-paclitaxel in combination with carboplatin can be a favorable chemotherapy regimen for advanced thymic carcinoma.

DOI： 10.1159/000357938

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Diffuse parenchymal pulmonary amyloidosis showing an objective response to bortezomib-based chemotherapy.

Hisao Higo, Keiichi Fujiwara, Hiromi Watanabe, Go Makimoto, Nobuhisa Kameyama, Mizuho Matsushita, Kammei Rai, Ken Sato, Tomoko Inomata, Kazutaka Sunami, Takuo Shibayama

Internal medicine (Tokyo, Japan) 53 ( 16 ) 1809 - 12 2014

Language：English Publishing type：Research paper (scientific journal)

A 77-year-old woman was admitted because of bilateral hand numbness and dyspnea on exertion. Her serum IgG was increased, and a bone marrow aspiration analysis supported a diagnosis of multiple myeloma. Additionally, computed tomography scans of the chest showed bilateral ground glass attenuations, linear opacities, and consolidations. Transbronchial lung biopsy revealed Congo Red-positive amorphous eosinophilic deposits. She was therefore diagnosed with diffuse parenchymal pulmonary amyloidosis accompanied by multiple myeloma. Following combination chemotherapy including bortezomib, her serum monoclonal protein levels were normalized, and pulmonary function and oxygenation improved.

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Two cases of possible neuro-Sweet disease with meningoencephalitis as the initial manifestation. International journal

Go Makimoto, Yasuhiro Manabe, Chizuru Yamakawa, Daiki Fujii, Yasuko Ikeda-Sakai, Hisashi Narai, Nobuhiko Omori, Koji Abe

Neurology international 4 ( 1 ) e5 2012.1

Language：English

We report 2 cases that were considered to be neuro-Sweet disease. They initially manifested with meningoencephalitis and no skin lesions, and rapidly improved with corticosteroid therapy. In both cases, patients complained of meningitic symptoms such as fever and headache, and HLA-B54 and -Cw1 turned out to be positive over the clinical course. Cerebrospinal fluid analysis showed increased levels of lymphocytes and protein. In case #1, fluid-attenuated inversion recovery (FLAIR), magnetic resonance imaging (MRI) and diffusion-weighted images (DWI) showed high-intensity signals in the right dorsal medulla oblongata, bilateral dorsal midbrain, and left thalamus. In case #2, FLAIR and DWI showed high-intensity signals in the bilateral cerebellar cortex and left caudate nucleus. Symptoms and MRI images were markedly improved in both cases after corticosteroid pulse therapy. According to published diagnostic criteria, these 2 cases were considered possible neuro-Sweet disease. These cases suggest that the combination of meningoencephalitis and HLA specificity is important to consider the possibility of neuro-Sweet disease, even without skin lesions.

DOI： 10.4081/ni.2012.e5

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Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome. International journal

Go Makimoto, Michiko Asano, Nobukazu Fujimoto, Yasuko Fuchimoto, Katsuichiro Ono, Shinji Ozaki, Koji Taguchi, Takumi Kishimoto

Case reports in rheumatology 2012 640353 - 640353 2012

Language：English Publishing type：Research paper (scientific journal)

Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms. Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericarditis. We report a case of SS presenting initially with bilateral pleural effusions. A 63-year old man was admitted to our hospital with a one-month history of cough, dyspnea, and right chest pain. Chest-computed tomography revealed bilateral pleural effusions. Serum anti-SS-A antibody titer was 1 : 256. Ophthalmological examination revealed a positive Schirmer test. Lip biopsy showed atrophy and plasmacytic infiltration of the salivary gland. Corticosteroid treatment was initiated. Pleural effusions were almost completely resolved by day 30. The patient has not experienced any recurrence.

DOI： 10.1155/2012/640353

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Papers - Makimoto Go