研究者詳細 - 押木　俊之

MISC - 押木　俊之

分割表示 99 件中 41 - 60 件目／全件表示 >>

2元機能型錯体触媒による水和反応

押木俊之

月刊ファインケミカル 38 ( 10 ) 6 - 14 2009年

環境対応型の加水分解触媒技術革新的化学触媒を用いるニトリル類の水和(加水分解)技術

押木俊之

クリーンテクノロジー ( 3 ) 51 - 54 2009年

生体触媒の制約を超える人工加水分解触媒

押木俊之

日本化学会講演予稿集 89th ( 1 ) 2009年

高活性錯体触媒法によるアミド製造法の開発

押木俊之, 石塚章斤, 兵頭功

ケミカルエンジニヤリング 53 ( 6 ) 440 - 444 2008年

Alkyne Exchange Reactions of Silylalkyne Complexes of Tantalum: Mechanistic Investigation and its Application in the Preparation of New Tantalum Complexes Having Functional Alkynes (PhC≡CR (R = COOMe, CONMe2))

Toshiyuki Oshiki, Atsushi Yamada, Kimio Kawai, Hirotaka Arimitsu, Kazuhiko Takai

Organometallics 26 ( 1 ) 173 - 182 2007年1月

Analgesic agents without gastric damage: Design and synthesis of structurally simple benzenesulfonanilide-type cyclooxygenase-1-selective inhibitors

Xiaoxia Zheng, Hiroyuki Oda, Kayo Takamatsu, Yukio Sugimoto, Akihiro Tai, Eiichi Akaho, Hamed Ismail Ali, Toshiyuki Oshiki, Hiroki Kakuta, Kenji Sasaki

BIOORGANIC & MEDICINAL CHEMISTRY 15 ( 2 ) 1014 - 1021 2007年1月

記述言語：英語出版者・発行元：PERGAMON-ELSEVIER SCIENCE LTD

In order to create novel analgesic agents without gastric disturbance, structurally simple cyclooxygenase-1 (COX-1) inhibitors with a benzenesulfonanilide skeleton were designed and synthesized. As a result, compounds 11f and 15a, which possess a p-amino group on the benzenesulfonyl moiety and p-chloro group on the anilino moiety, showed COX-1-selective inhibition. Moreover compound 11f, which is the most potent compound in this study showed more potent analgesic activity than that of aspirin at 30 mg/kg by po. The anti-inflammatory activity and gastric damage, however, were very weak or not detectably different from aspirin. Since the structure of our COX-1 inhibitors are very simple, they may be useful as lead compounds for superior COX-1 inhibitors as analgesic agents without gastric disturbance. (c) 2006 Published by Elsevier Ltd.

DOI： 10.1016/j.bmc.2006.10.029

Web of Science

researchmap

ニトリル類の水和反応を無溶媒で触媒する新規高活性イリジウム錯体の開発

押木俊之, 石塚章斤, 兵頭功, 有光寛高, 高井和彦

触媒 49 ( 6 ) 412 - 414 2007年

Titanium and zirconium complexes with non-salicylaldimine-type imine-phenoxy chelate ligands: Syntheses, structures, and ethylene-polymerization behavior

Yasuhiko Suzuki, Hidetsugu Tanaka, Toshiyuki Oshiki, Kazuhiko Takai, Terunori Fujita

CHEMISTRY-AN ASIAN JOURNAL 1 ( 6 ) 878 - 887 2006年12月

記述言語：英語掲載種別：書評論文，書評，文献紹介等出版者・発行元：WILEY-V C H VERLAG GMBH

New Ti and Zr complexes that bear imine-phenoxy chelate ligands, [12,4-di-tBu-6-(RCH=N)C6H40}MCl2] (1: M=Ti, R=Ph; 2: M=Ti, R=C6F5; 3: M=Zr, R=Ph; 4: M=Zr, R=C6F5), were synthesized and investigated as precatalysts for ethylene polymerization. H-1 NMR spectroscopy suggests that these complexes exist as mixtures of structural isomers. X-ray crystallographic analysis of the adduct 1 center dot HCl reveals that it exists as a zwitterionic complex in which H and Cl are situated in close proximity to one of the imine nitrogen atoms and the central metal, respectively. The Xray molecular structure also indicates that one imine phenoxy group with the syn C=N configuration functions as a bidentate ligand, whereas the other, of the anti C=N form, acts as a monodentate phenoxy ligand. Although Zr complexes 3 and 4 with methylaluminoxane (MAO) or [Ph3C](+)[B(C6F5)(4)]/AliBu(3)displayed moderate activity, the Ti congeners 1 and 2, in association with an appropriate activator, catalyzed ethylene polymerization with high efficiency. Upon activation with MAO at 25 degrees C, 2 displayed a very high activity of 19900 (kg PE) (mol Ti)(-1)h(-1), which is comparable to that for [Cp2TiCl2] and [Cp2ZrCl2], although increasing the polymerization temperature did result in a marked decrease in activity. Complex 2 contains a C6F5 group on the imine nitrogen atom and mediated nonliving-type polymerization, unlike the corresponding salicylaldimine-type complex. Conversely, with [Ph3C](-)/[B(C6F5)(4)](-)/AliBu(3) activation, 1 exhibited enhanced activity as the temperature was increased (25-75 degrees C) and maintained very high activity for 60 min at 75 degrees C (18740 (kg PE) (mol Ti)(-1)h(-1)). H-1 NMR spectroscopic studies of the reaction suggest that this thermally robust catalyst system generates an amine-phenoxy complex as the catalytically active species. The combinations 1/[Ph3C](+)[B(C6F5)(4)](-)/AliBu(3) and 2/MAO also worked as high-activity catalysts for the copolymerization of ethylene and propylene.

DOI： 10.1002/asia.200600256

Web of Science

researchmap

Dramatic rate acceleration by a diphenyl-2-pyridylphosphine ligand in the hydration of nitriles catalyzed by Ru(acac)(2) complexes

T Oshiki, H Yamashita, K Sawada, M Utsunomiya, K Takahashi, K Takai

ORGANOMETALLICS 24 ( 26 ) 6287 - 6290 2005年12月

記述言語：英語出版者・発行元：AMER CHEMICAL SOC

New ruthenium(II) complexes having acac (=acetylacetonato) and diphenyl-2-pyridylphosphine as ligands proved to be excellent catalysts for hydration of nitriles to amides under neutral conditions. Among the ruthenium complexes examined, cis-Ru(acac)(2)(PPh(2)py)(2) exhibited the highest activity, with a turnover frequency of up to 20900 (mol of amide)/((mol of catalyst) h).

DOI： 10.1021/om050792b

Web of Science

researchmap

A novel heteroligated phenoxy-based titanium complex: Structure, stability, and ethylene polymerization behavior

Y Suzuki, T Oshiki, H Tanaka, K Takai, T Fujita

CHEMISTRY LETTERS 34 ( 10 ) 1458 - 1459 2005年10月

記述言語：英語出版者・発行元：CHEMICAL SOC JAPAN

A new phenoxy-imine and phenoxy-ketone heteroligated titanium complex was obtained by hydrolysis of one of the two imine moieties of a bis(phenoxy-imine)Ti complex. X-ray diffraction analysis revealed that the complex assumes an octahedral coordination geometry with a cis-phenoxy-O's and cis-Cl's disposition. NMR studies demonstrated that the complex does not undergo disproportionation. In association with methylaluminoxane, the complex behaved as a non-living-type single-site catalyst for ethylene polymerization.

DOI： 10.1246/cl.2005.1458

Web of Science

researchmap

Synthesis of bis(phenoxyimine) Ti alkyl complexes and observation of living species by H-1 NMR spectroscopy

H Makio, T Oshiki, K Takai, T Fujita

CHEMISTRY LETTERS 34 ( 10 ) 1382 - 1383 2005年10月

記述言語：英語出版者・発行元：CHEMICAL SOC JAPAN

Synthesis of [C6F5N=CH(2-O-C6H3-3-R)](2)TiMex (R: Bu-t; X: Br (2), R: Bu-t; X: Me (3), R: H; X: Me (4)) was achieved by the reaction of methylated titanium halides with sodium salts of the phenoxyimine ligands. These complexes can be activated with equimolar amounts of B(C6F5)(3) or Ph3CB(C6F5)(4) to form methyl cationic species, which, upon addition of a small amount of ethylene monomer allows room temperature observation of cationic polymeryl species.

DOI： 10.1246/cl.2005.1382

Web of Science

researchmap

Low-temperature catalytic hydrothermal treatment of wood biomass: analysis of liquid products

S Karagoz, T Bhaskar, A Muto, Y Sakata, T Oshiki, T Kishimoto

CHEMICAL ENGINEERING JOURNAL 108 ( 1-2 ) 127 - 137 2005年4月

記述言語：英語出版者・発行元：ELSEVIER SCIENCE SA

Catalytic hydrothermal treatment of wood biomass was performed at 280&DEG; C for 15 min in the presence of alkaline solutions (NaOH, Na2CO3, KOH and K2CO3). Oil products were extracted from both liquid and solid portion by different solvents and analyzed individually. The effect of base solutions on the yield of oil products and composition of oils obtained at different stages were discussed in detail. Based on the conversion and yield of liquid products, the catalytic activity can be ranked as follows: K2CO3 &GT; KOH &GT; Na2CO3 &GT; NaOH. In thermal run, the yield of solid residue was about 42% whereas it was 4.0% in the presence of K2CO3. Catalytic hydrothermal treatment of biomass produced mainly phenolic compounds. In thermal run, furan derivatives were observed whereas these compounds could not be observed in catalytic runs. The volatility distribution of hydrocarbons (ether extract) was characterized by using C-NP gram and it showed that the majority of hydrocarbons for all runs including thermal were distributed boiling point range of n-C-11. The products from hydrothermal treatment of wood biomass were analyzed using GC-MS, H-1 NMR, C-13 NMR, TOC and ion chromatograph. &COPY; 2005 Elsevier B.V. All rights reserved.

DOI： 10.1016/j.cej.2005.01.007

Web of Science

researchmap

Catalytic performance of tantalum-eta(2)-alkyne complexes [TaCl3((RC)-C-1 CR2)L-2] for alkyne cyclotrimerization

T Oshiki, H Nomoto, K Tanaka, K Takai

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN 77 ( 5 ) 1009 - 1011 2004年5月

記述言語：英語出版者・発行元：CHEMICAL SOC JAPAN

Structurally characterized tantalum-eta(2)-alkyne complexes [TaCl3(eta(2)-EtCdropCEt)L-2] (1, L-2 = 1,2-dimethoxyethane (DME); 2, L = py) acted as catalysts for the cyclotrimerization of terminal alkynes. The catalytic reaction proceeded at 25 degreesC within few hours and the trisubstituted benzenes were obtained without the formation of linear oligomers. A new tantalum complex having a terminal alkyne ligand, [TaCl3(eta(2)-Me(3)SiCdropCH)(dme)] (3), was prepared, and its catalytic performance was also investigated.

DOI： 10.1246/bcsj.77.1009

Web of Science

researchmap

Preparation, structural characterization, and reactions of tantalum-alkyne complexes TaCl3((RC)-C-1 CR2)L-2 (L-2 = DME, bipy, and TMEDA; L = Py)

T Oshiki, K Tanaka, J Yamada, T Ishiyama, Y Kataoka, K Mashima, K Tani, K Takai

ORGANOMETALLICS 22 ( 3 ) 464 - 472 2003年2月

記述言語：英語出版者・発行元：AMER CHEMICAL SOC

Tantalum-alkyne complexes with the general formula TaCl3(R(1)CdropCR(2))(dme) (1a, R-1 = R-2 = Et; 1b, R-1 = R-2 = n-C5H11; 1c, R-1 = Ph, R-2 = Me; 1d, R-1 = R-2 = Ph; DME = 1,2-dimethoxyethane) were synthesized by treatment of the corresponding alkynes with a low-valent tantalum derived by reduction of tantalum pentachloride with zinc powder in a mixed solvent of toluene and DME. The DME ligand can be replaced by 2 equiv of pyridine to afford the corresponding dipyridine complexes TaCl3(R(1)CdropCR(2))(py)(2) (2a, R-1 = R-2 = Et; 2b, R-1 = R-2 = n-C5H11; 2c, R-1 = Ph, R-2 = Me; 2d, R-1 = R-2 = Ph). Additionally, the reaction of 1a with the bidentate nitrogen ligands bipyridine and N,N,N',N'-tetramethyethylenediamine (= TMEDA) gave TaCl3(EtCdropCEt)(bipy) (3) and TaCl3(EtCdropCEt)(tmeda) (4), respectively. The eta(2)- and 4e-coordination mode of an alkyne with a large contribution of a metalacyclopropene canonical structure was revealed by spectroscopic methods (NMR and IR) and crystallographic analyses of 1a, 1c, 2a, and 4. The reactivies of the tantalum-3-hexyne complexes la, 2a, 3, and 4 toward 3-phenylpropanal were investigated. Only the pyridine complex 2a reacted with a stoichiometric amount of the aldehyde to afford the corresponding allylic alcohol in 77% yield upon hydrolysis. The reaction proceeded via an oxatantalacyclopentene species.

DOI： 10.1021/om020510x

Web of Science

researchmap

私の産学連携への取り組み

押木俊之

触媒 45(8), 674 2003年

Synthesis and ethylene polymerization behavior of Ti and Zr complexes having imine-phenoxy chelate ligands.

Y Suzuki, T Oshiki, K Takai, N Kashiwa, T Fujita

ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 223 A80 - A81 2002年4月

新しい均一系クロム錯体触媒によるオレフィン重合

押木俊之

触媒第43巻3号235頁 2001年

錯体触媒によるC-H結合活性化を利用した置換ベンゼン類の新合成法

押木俊之

Organometallic News 3号, 103頁 2001年

Determination of the absolute configuration of partly fluorinated allylic alcohols; the first synthesis of optically pure 1,2-difluoroallylic alcohols

Yumiko Takagi, Takiko Nakatani, Toshiyuki Itoh, Toshiyuki Oshiki

Tetrahedron Letters 41 ( 41 ) 7889 - 7892 2000年10月

Determination of the absolute configuration of partly fluorinated allylic alcohols; the first synthesis of optically pure 1,2-difluoroallylic alcohols

Y Takagi, T Nakatani, T Itoh, T Oshiki

TETRAHEDRON LETTERS 41 ( 41 ) 7889 - 7892 2000年10月

記述言語：英語出版者・発行元：PERGAMON-ELSEVIER SCIENCE LTD

Optically active 1,1,2-trifluoro- or 1,2-difluoroallylic alcohols were prepared via a lipase-catalyzed reaction and their absolute configuration was determined by an X-ray crystallographic analysis of the corresponding ferrocene ester along with the refined Mosher method (the Kusumi-Ohtani method). (C) 2000 Elsevier Science Ltd. All rights reserved.

DOI： 10.1016/S0040-4039(00)01349-6

Web of Science

researchmap

　前のページ - 次のページ　

<押木 俊之>

MISC - 押木 俊之

<押木　俊之>

MISC - 押木　俊之