研究者詳細 - 寺東　宏明

MISC - 寺東　宏明

分割表示 82 件中 41 - 60 件目／全件表示 >>

Repair roles of hSMUG1 assessed by damage specificity and cellular activity 国際誌

Aya Masaoka, Mayumi Matsubara, Tamon Tanaka, Hiroaki Terato, Yoshihiko Ohyama, Kihei Kubo, Hiroshi Ide

Nucleic Acids Research Supplement 3 263 - 264 2003年

Identification and characterization of mammalian 5-formyluracil-DNA glycosylase 国際誌

Mayumi Matsubara, Aya Masaoka, Tamon Tanaka, Hiroaki Terato, Yoshihiko Ohyama, Hiroshi Ide

Nucleic Acids Research Supplement 3 233 - 234 2003年

Repair of oxidative cytosine damage by DNA glycosylases 国際誌

Atsushi Katafuchi, Aya Matsuo, Hiroaki Terato, Yoshihiko Ohyama, Hiroshi Ide

Nucleic Acids Research Supplement 3 269 - 270 2003年

記述言語：英語

5-Hydroxyuracil (HOU) and 5-hydroxycytosine (HOC) are major oxidative lesions of cytosine with mutagenic potentials. Therefore, HOU and HOC need to be removed from DNA to avoid mutation. In this study, oligonucleotide substrates containing HOU and HOC were synthesized by DNA polymerase reactions and tested for DNA glycosylases. Ung exhibited an extremely low activity for HOU as compared to uracil (U). In contrast, hSMUG1 excised HOU and U with a comparable efficiency. Ung and hSMUG1 did not excise HOC.

PubMed

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89 Identification of a Mammalian 5-Formyluracil-DNA Glycosylase and its Substrate Recognition Mechanism(Repair of radiation damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society) :

TANAKA Tamon, MATSUBARA Mayumi, MASAOKA Aya, KUBO Kihei, TERATO Hiroaki, OHYAMA Yoshihiko, IDE Hiroshi

Journal of radiation research 44 ( 4 ) 408 - 408 2003年

201 The Repair Mechanism of a Crosslink Lesion of Oxanine Generated by NO(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society) :

NAKANO Toshiaki, SIMIZU Ryoko, TERATO Hiroaki, BENNET Houten, IDE Hiroshi

Journal of radiation research 44 ( 4 ) 436 - 436 2003年

202 Quantitation of DNA damage induced by high LET particles(Physics, chemistry and DNA damage, Abstracts of the 46th Annual Meeting of the Japan Radiation Research Society) :

TANAKA Ruri, NAKAARAI Yusuke, TERATO Hiroaki, FURUSAWA Yoshiya, IDE Hiroshi

Journal of radiation research 44 ( 4 ) 436 - 436 2003年

Detection of NO-induced DNA lesions by the modified aldehyde reactive probe (ARP) assay. 国際誌

Toshiaki Nakano, Hiroaki Terato, Yoshihiro Yoshioka, Yoshihiko Ohyama, Kihei Kubo, Hiroshi Ide

Nucleic Acids Research Supplement 2 239 - 240 2002年

Purification of a Repair Enzyme for 5-Formyluracil :

MATSUBARA Mayumi, TANAKA Tamon, MASAOKA Aya, KUBO Kihei, TERATO Hiroaki, OHYAMA Yoshihiko, IDE Hiroshi

Journal of radiation research 43 ( 4 ) 446 - 446 2002年

Translesion DNA Synthesis Past a FapyG Lesion by E. coli DNA Polymerase I :

ASAGOSHI Kenjiro, TERATO Hiroaki, OHYAMA Yoshihiko, IDE Hiroshi

Journal of radiation research 43 ( 4 ) 448 - 448 2002年

Adduct formation between oxanine and amine derivatives.

Nakano, T., Terato, H., Asagoshi, K., Ohyama, Y., Suzuki, T., Yamada, M., Makino, K., Ide, H.

Nucleic acids research. Supplement (2001) 1 ( 1 ) 47 - 48 2001年

Quantitation of DNA damage by an aldehyde reactive probe (ARP).

Kurisu, S., Miya, T., Terato, H., Masaoka, A., Ohyama, Y., Kubo, K., Ide, H.

Nucleic acids research. Supplement (2001) 1 ( 1 ) 45 - 46 2001年

Mechanism to maintain genetic information in Halobacterium salinarium, a halophilic bacterium.

Terato, H, Asgarani, E, Funamizu, H, Saito, T, Shahmohammadi, H. R, Ide, H

Mutation Research, Fundamental and Molecular Mechanisms of Mutagenesis 2001年

Recognition of 5-Formyluracil by Repair Enzymes for Oxidative Damage :

MASAOKA Aya, HASEGAWA Rei, MATSUBARA Mayumi, TERATO Hiroaki, OHYAMA Yoshihiko, IDE Hiroshi

Journal of radiation research 42 ( 4 ) 482 - 482 2001年

Detection of Radiation-Induced DNA Damage by an Aldehyde Reactive Probe (ARP) :

TERATO Hiroaki, KURISU Satofumi, MIYA Toshinobu, ALI Mohammed Mohsin, OHYAMA Yoshihiko, KUBO Kihei, IDE Hiroshi

Journal of radiation research 42 ( 4 ) 465 - 465 2001年

Enzymatic properties of Escherichia coli and human 7, 8-dihysro-8-oxoguanine DNA glycosylase.

Asagoshi, K, Yamada, T, Terato, H, Ohyama, Y, Ide, H

Nucleic Acids Symposium Series 44 11 - 12 2000年

DNA protection ability of intracellular highly concentrated salts on Halobacterium salinarium, an extremely halophilic bacterium

H Terato, E Asgarani, HR Shahmohammadi, H Funamizu, T Saito, H Ide

8TH WORLD SALT SYMPOSIUM, VOLS 1 AND 2 927 - 931 2000年

担当区分：筆頭著者,　責任著者記述言語：英語出版者・発行元：ELSEVIER SCIENCE BV

Halobacterium salinarium is an extremely halophilic archaebacterium, which lives in the surface of salt lake and salt plant. In these environments, H. salinarium is usually exposed by intense irradiation of sunlight including ultraviolet light (UV). UV produces DNA lesions, and possesses mutagenic and/or lethal effects on organisms. H. salinarium can tolerant various DNA-damaging agents such as UV and gamma rays. H. salinarium contains saturated concentrations of K+ and Cl- in the cell. Since Cl- is known to be a radical scavenger, the intracellular highly accumulated ions seem to be involved in the DNA protection. In vitro, highly concentrated KCI inhibited the generations of cyclobutane pyrimidine dimer (CPD) and DNA strand break, the DNA lesions induced by UV and gamma rays, respectively. These protection efficiencies are larger than that shown by carotenoid, an abandon antioxidant in the cell of H. salinarium. Therefore the intracellular highly concentrated salts play effective role not only to tolerant against osmotic pressure, but also to maintain the genetic information in the extremely severe environment.

Web of Science

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Preparation and enzymatic recognition of guanine lesions induced by nitrogen oxides.

Masaoka, A, Terato, H, Honsho, A, Ohyama, Y, Suzuki, T, Yamada, M, Makino, K, Ide, H

Nucleic Acids Symposium Series 44 87 - 88 2000年

Substrate Specificities of Endonuclease III Homologues :

ODAWARA Hiroaki, MIYANO Takayuki, TERATO Hiroaki, OHYAMA Yoshihiko, IDE Hiroshi

Journal of radiation research 41 ( 4 ) 423 - 423 2000年

Recognition of Formamidopyrimidine by Endonuclease III Homologues :

ASAGOSHI Kenjiro, YAMADA Takao, OKADA Yumiko, TERATO Hiroaki, OHYAMA Yoshihiko, YAMAMOTO Kazuo, IDE Hiroshi

Journal of radiation research 41 ( 4 ) 422 - 422 2000年

Preparation of DNA containing 7-methylguanine as unique lesions.

Asagoshi, K, Terato, H, Ohyama, Y, Ide, H

Nucleic Acids Symposium Series 42 83 - 84 1999年

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