研究者詳細 - 内山　淳平

MISC - 内山　淳平

分割表示 322 件中 221 - 240 件目／全件表示 >>

C型ボツリヌス毒素変換ファージのゲノム比較と遺伝子機能解析(The genome sequence of Clostridium botulinum type C phage and functional analysis of gene products)

阪口義彦, 内山淳平, 小椋義俊, 山本由弥子, 松崎茂展, 林哲也, 松下治, 小熊惠二, 林俊治

日本細菌学雑誌 71 ( 1 ) 135 - 135 2016年2月

ファージ・ルネッサンスファージ発見から100年たった今ファージを利用した細菌検出黄色ブドウ球菌検出ファージクロマト法の開発

松井秀仁, 内山淳平, 津田愛美, 松崎茂展, 花木秀明

日本細菌学雑誌 71 ( 1 ) 54 - 54 2016年2月

緑膿菌PAO1株とファージKPP22の短期間進化的軍拡競走の解析

那須川忠弥, 内山淳平, 鈴木仁人, 宮田玲奈, 山口琴絵, 内山伊代, 阪口義彦, 柴山恵吾, 阪口雅弘, 松崎茂展

日本細菌学雑誌 71 ( 1 ) 92 - 92 2016年2月

Helicobacter pylori ファージとそのゲノム

内山淳平, 竹内啓晃, 松崎茂展

Helicobacter Research 20 50 - 54 2016年

電解加工を用いた小径曲がり穴加工における加工速度

内山光夫, 黒澤圭汰, 鈴木淳平

電気加工学会誌 50 ( 123 ) 36 - 42 2016年

食物有害反応を示す犬における卵白アレルゲンに対するIgE反応性の検討

島倉秀勝, 齋藤拓, 藤村正人, 岡本憲明, 内山淳平, 阪口雅弘

日本獣医学会学術集会講演要旨集 158回 401 - 401 2015年8月

細菌感染症における診断法と治療法の開発バクテリオファージの利用

内山淳平, 松井秀仁, 阪口義彦, 花木秀明, 松崎茂展, 阪口雅弘

日本獣医学会学術集会講演要旨集 158回 182 - 182 2015年8月

イヌにおける新規口腔内常在細菌の同定と全ゲノム配列解析

平山隆一郎, 鈴木仁人, 内山淳平, 松井真理, 鈴木里和, 柴山恵吾, 阪口雅弘, 木内明男

日本獣医学会学術集会講演要旨集 158回 313 - 313 2015年8月

眼感染症に対するファージ療法の研究開発および臨床応用への問題点

福田憲, 石田わか, 内山淳平, 松崎茂展, 福島敦樹

日本獣医学会学術集会講演要旨集 158回 183 - 183 2015年8月

Evaluation of the lubrication mechanism at various rotation speeds and granule filling levels in a container mixer using a thermal effusivity sensor 査読国際誌

Jumpei Uchiyama, Shigeru Aoki

DRUG DEVELOPMENT AND INDUSTRIAL PHARMACY 41 ( 7 ) 1172 - 1181 2015年7月

記述言語：英語出版者・発行元：TAYLOR & FRANCIS LTD

To research the detailed mechanism of the lubrication process using the thermal effusivity sensor, the relationships of the lubrication progress with the pattern of powder flow, the rotation speed and the filling level were investigated. The thermal effusivity profile was studied as a function of the number of rotations at various rotation speeds. It was observed that at lower rotation speeds, the profiles of the lubrication progress were almost the same, regardless of the rotation speed. In this region, the highest speed was defined as the critical rotation speed (CRS), which was found to be one of the important factors. The CRS had close relations with avalanche flow in the blender. The first and the second phases were observed in the lubrication process. The first phase was influenced by the CRS and the filling level in the blender. The second phase was influenced by the rotation speed. The mechanism of two-phase process was proposed as a macro progression of the dispersion of the lubricant (first phase) and micro progression of the coating of the powder particles with lubricant (second phase). The accurate monitoring by the thermal effusivity sensor was able to help a better understanding in the lubrication process.

DOI： 10.3109/03639045.2014.935394

ファージ尾部タンパクを用いた黄色ブドウ球菌検出方法の開発

松井秀仁, 崔龍洙, 花木秀明, 内山淳平, 松崎茂展

日本化学療法学会雑誌 63 ( Suppl.A ) 170 - 170 2015年5月

New Approach to Evaluate the Lubrication Process in Various Granule Filling Levels and Rotating Mixer Sizes Using a Thermal Effusivity Sensor 査読

Jumpei Uchiyama, Shigeru Aoki, Yoshifumi Uemoto

CHEMICAL & PHARMACEUTICAL BULLETIN 63 ( 3 ) 164 - 179 2015年3月

記述言語：英語出版者・発行元：PHARMACEUTICAL SOC JAPAN

The principles of thermal effusivity are applied to an understanding of the detailed mechanisms of the lubrication process in a rotating mixer. The relationships and impact of the lubrication process by the pattern of powder flow, the filling level, and the rotating mixer size were investigated. Thermal effusivity profiles of the lubrication process, as obtained, indicate that lubrication is a two-phase process. The intersection point of the first and second phases (IPFS) is influenced by changing the filling level, thus changing the resulting number of avalanche flows created. The slope of the second phase (SSP) is influenced by the relationship between the number and the length of avalanche flows. Understanding this difference between the first and second phases is important to successfully evaluate the impact of proposed changes in the lubrication process. From this knowledge, a predictive model of the lubrication profile can be generated to allow an evaluation of proposed changes to the lubrication process. This model allows estimation of the lubrication profile at different filling levels and in different rotating mixer sizes. In this study, the actual lubrication profile almost coincides with the model predicted lubrication profile. Based on these findings, it is assumed that lubrication profiles at a commercial scale can be predicted from data generated at the laboratory scale. Further, it is assumed that changes in the filling level can also be estimated from the laboratory or current data.

DOI： 10.1248/cpb.c14-00634

B型ボツリヌス菌のボツリヌス毒素遺伝子をコードするプラスミド解析(Analysis of botulinum neurotoxin type B6 gene-encoding plasmid in Clostridium botulinum type B)

阪口義彦, 内山淳平, 細見晃司, 幸田知子, 松崎茂展, 小椋義俊, 林哲也, 林俊治, 小崎俊司, 向本雅郁

日本細菌学雑誌 70 ( 1 ) 178 - 178 2015年2月