2024/05/28 更新

写真a

ワン ジン
WANG JIN
WANG JIN
所属
ヘルスシステム統合科学学域 准教授
職名
准教授
プロフィール

              

学位

  • 博士(生物工学) ( 2015年7月   筑波大学 )

研究分野

  • ナノテク・材料 / ナノマイクロシステム

  • ナノテク・材料 / 分析化学

  • ものづくり技術(機械・電気電子・化学工学) / 電子デバイス、電子機器

  • ナノテク・材料 / 生物分子化学

学歴

  • 筑波大学   Graduate School of Life and Environmental Sciences  

    2012年8月 - 2015年7月

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経歴

  • 岡山大学   学術研究院ヘルスシステム統合科学学域   准教授

    2024年4月 - 現在

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  • 岡山大学   学術研究院ヘルスシステム統合科学学域   助教

    2020年4月 - 2024年3月

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  • 九州大学   システム情報科学研究院 / 五感応用デバイス研究開発センター   JST ImPACT&CREST 特任助教/学術研究員

    2015年8月 - 2020年3月

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委員歴

  • The 11th East Asia Symposium on Superconductor Electronics (EASSE 2023) Secretary  

    2022年1月 - 2023年4月   

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    団体区分:学協会

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  • 電気学会全国大会   実行委員会  

    2021年10月 - 現在   

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    団体区分:学協会

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論文

  • Label-Free Measurement of CD63 Positive Extracellular Vesicles Using Terahertz Chemical Microscopy 査読

    Changjiang Liu, Jin Wang, Ryo Negishi, Tatsutoshi Inuzuka, Toshihiko Kiwa

    ACS Sensors   2024年5月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:American Chemical Society (ACS)  

    DOI: 10.1021/acssensors.4c00590

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  • Ultrathin Platinum Film Hydrogen Sensors with a Twin-T Type Notch Filter Circuit 査読

    Shoki Wakabayashi, Yuki Oh, Haruhito Nakayama, Jin Wang, Toshihiko Kiwa

    Sensors   24 ( 2 )   548 - 548   2024年1月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:MDPI AG  

    In recent years, hydrogen energy has garnered attention as a potential solution for mitigating greenhouse gas emissions. However, concerns regarding the inherent risk of hydrogen gas leakage and potential explosions have necessitated the development of advanced sensors. Within our research group, we have innovated an ultrathin platinum (Pt) film hydrogen sensor that gauges resistance changes in Pt thin films when exposed to hydrogen gas. Notably, the sensitivity of each sensor is contingent upon the thickness of the Pt film. To address the challenge of detecting hydrogen using multiple sensors, we integrated the ultrathin Pt film as a resistance element within a twin-T type notch filter. This filter exhibits a distinctive reduction in output signals at a specific frequency. The frequency properties of the notch filter dynamically alter with changes in the resistance of the Pt film induced by hydrogen exposure. Consequently, the ultrathin Pt film hydrogen sensor monitors output signal variations around the notch frequency, responding to shifts in frequency properties. This innovative approach enables the electrical control of sensor sensitivity by adjusting the operating frequency in proximity to the notch frequency. Additionally, the simultaneous detection of hydrogen by multiple sensors was successfully achieved by interconnecting sensors with distinct notch frequencies in series.

    DOI: 10.3390/s24020548

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  • Terahertz aptasensor for dopamine neurochemical detection 査読

    Jin Wang, Kosei Morita, Masaki Ando, Sota Yoshida, Hiroki Nagata, Kenji Sakai, Toshihiko Kiwa

    Applied Physics Express   2023年5月

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)  

    DOI: 10.35848/1882-0786/acd102

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  • Aggregation of magnetic nanoparticles in biological solvents evaluated by HTS-SQUID magnetic immunoassay system 査読

    K. Yamashita, K. Kishimoto, H. Kuroda, J. Wang, K. Sakai, M. M. Saari, T. Kiwa

    IEEE Transactions on Applied Superconductivity   33 ( 5 )   1 - 6   2023年1月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Institute of Electrical and Electronics Engineers (IEEE)  

    DOI: 10.1109/tasc.2023.3239830

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  • Multifunctional terahertz microscopy for biochemical and chemical imaging and sensing 査読

    Jin Wang, Masaki Ando, Hiroki Nagata, Sota Yoshida, Kenji Sakai, Toshihiko Kiwa

    Biosensors and Bioelectronics   220   114901 - 114901   2023年1月

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier BV  

    DOI: 10.1016/j.bios.2022.114901

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  • All-in-one terahertz taste sensor: integrated electronic and bioelectronic tongues 査読

    Jin Wang, Kenji Sakai, Toshihiko Kiwa

    Sensors & Diagnostics   2023年

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)   出版者・発行元:Royal Society of Chemistry (RSC)  

    Taste sensors, also known as electronic tongues or bioelectronic tongues, are designed to evaluate food and beverages, as well as for medical diagnostics. This device mimics the ability of the...

    DOI: 10.1039/d3sd00038a

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  • Comparative Study of Terahertz Chemical Microscopy and Flexible ISFET Approaches for Calcium Ion Detection 査読

    Sota Yoshida, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2023年

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    掲載種別:研究論文(国際会議プロシーディングス)  

    In this study, we conducted a comprehensive comparison of two advanced techniques, terahertz chemical microscopy (TCM) and ion-sensitive field-effect transistors (ISFET), for calcium ion detection. The results revealed the advantages and limitations of TCM and flexible ISFET, offering valuable insights into their applications and improvements.

    DOI: 10.1109/IRMMW-THz57677.2023.10299237

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  • Detection of Nucleocapsid Proteins of COVID-19 using a Terahertz Chemical Microscope 査読

    Xue Ding, Sayaka Tsuji, Mana Murakami, Jin Wang, Hirofumi Inoue, Toshihiko Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2023年

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    掲載種別:研究論文(国際会議プロシーディングス)  

    Since the first person infected with COVID-19 was diagnosed in December 2019, the infection has spread rapidly all over the world. PCR and antigen testing are commonly used to detect infection, but detection sensitivity and sample size can be improved. In our group, a terahertz chemical microscope (TCM) has been developed. In this study, we successfully detected the SARS-CoV-2 nucleocapsid proteins (N protein) in solutions by immobilizing the aptamer and N protein on a sensing plate using avidin-biotin reaction.

    DOI: 10.1109/IRMMW-THz57677.2023.10298956

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  • Electric Potential Mapping Measurement for All-Solid-State Lithium-Ion Batteries using a Terahertz Chemical Microscope 査読

    Taketo Yamaguchi, Yusei Hosokawa, Ryota Tomie, Takumi Higuchi, Takashi Teranishi, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2023年

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    掲載種別:研究論文(国際会議プロシーディングス)  

    Terahertz Chemical Microscope (TCM) has been developed to measure the electric potential distribution of batteries during charging and discharging. The battery is mounted on a sensing plate with SiO2 and Si films on a sapphire substrate and irradiate with a femtosecond laser to generate THz pulses. THz amplitude is proportional to the electric potential on the sensing plate, so the electric potential distribution of the battery on the sensing plate can be measured. In this study, a method was developed to measure the cathode surface of an all-solid-state lithium ion battery by the TCM and visualized the electric potential distribution of the battery. This result shows that the TCM could be a useful tool for measuring of all-solid-state batteries.

    DOI: 10.1109/IRMMW-THz57677.2023.10299081

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  • Thickness Measurement at High Lift-Off for Underwater Corroded Iron-Steel Structures Using a Magnetic Sensor Probe 査読

    Shoya Adachi, Minoru Hayashi, Taisei Kawakami, Yuto Ando, Jin Wang, Kenji Sakai, Toshihiko Kiwa, Toshiyuki Ishikawa, Keiji Tsukada

    Sensors   2022年12月

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.3390/s23010380

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  • Dispersion of Fe3O4 Nanoparticle Beads Driven by Femtosecond Laser Pulses for Quantitative Magnetic Immunoassay Measurements 査読

    Kouhei Kishimoto, Hiroto Kuroda, Misaki Tsubota, Kei Yamashita, Jin Wang, Kenji Sakai, Mohd Mawardi Saari, Toshihiko Kiwa

    ACS Applied Nano Materials   5 ( 11 )   17258 - 17263   2022年11月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:American Chemical Society (ACS)  

    DOI: 10.1021/acsanm.2c04399

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  • A Hydrothermal Method to Generate Carbon Quantum Dots from Waste Bones and Their Detection of Laundry Powder 招待 査読

    Heng Ye, Binbin Liu, Jin Wang, Chunyu Zhou, Zhili Xiong, Longshan Zhao

    Molecules   27 ( 19 )   6479   2022年10月

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.3390/molecules27196479

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  • Optimization of Microchannels and Application of Basic Activation Functions of Deep Neural Network for Accuracy Analysis of Microfluidic Parameter Data 査読

    Feroz Ahmed, Masashi Shimizu, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    Micromachines   2022年8月

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.3390/mi13081352

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  • Rational Design of Peptides Derived from Odorant-Binding Proteins for SARS-CoV-2-Related Volatile Organic Compounds Recognition 査読

    Jin Wang, Kenji Sakai, Toshihiko Kiwa

    Molecules   27 ( 12 )   3917 - 3917   2022年6月

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)   出版者・発行元:{MDPI} {AG}  

    DOI: 10.3390/molecules27123917

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  • Crack Detection for Welded Joint with Surface Coating Using Unsaturated AC Magnetic Flux Leakage 査読

    Minoru Hayashi, Taisei Kawakami, Shoya Adachi, Jin Wang, Kenji Sakai, Toshihiko Kiwa, Keiji Tsukada, Yohei Miyamoto, Mikihito Hirohata, Toshiyuki Ishikawa

    IEEE Transactions on Magnetics   58 ( 8 )   1 - 1   2022年2月

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Institute of Electrical and Electronics Engineers ({IEEE})  

    DOI: 10.1109/tmag.2022.3151656

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  • A Versatile Terahertz Chemical Microscope and Its Application for the Detection of Histamine 査読

    Jin Wang, Kosuke Sato, Yuichi Yoshida, Kenji Sakai, Toshihiko Kiwa

    Photonics   9 ( 1 )   26 - 26   2022年1月

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)   出版者・発行元:{MDPI} {AG}  

    DOI: 10.3390/photonics9010026

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  • Electric Potential Mapping of All-Solid-State Lithium Ion Batteries using A Terahertz Chemical Microscope 査読

    Ryota Tomie, Taketo Yamaguchi, Masashi Shimizu, Kashu Hamada, Takashi Teranishi, Hidetoshi Nose, Masaki Kobayashi, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2022-August   2022年

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    掲載種別:研究論文(国際会議プロシーディングス)  

    A terahertz (THz) chemical microscope has been developed to measure the electric potential distribution of liquid phase lithium ion batteries (LIBs) during charging and discharging. A LIB was fabricated on a sensing plate, which consists of SiO2 and Si films on a sapphire substrate, to generate THz pulses by a laser irradiation. Since the amplitude of THz is proportional to the electric potential on the sensing plate, the electric potential distribution of the lithium ion battery on the sensing plate could be visualized. In this study, the electric potential distribution across a conventional all-solid-state LIB was measured by immobilizing the LIB on the sensing plate using epoxy resin. The distribution of the electric potentials of the battery was clearly visualized by the TCM. This result indicates that the TCM could be one of useful tools for the development high performance batteries.

    DOI: 10.1109/IRMMW-THz50927.2022.9896121

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  • Terahertz Chemical Microscope for Calcium Ions and Stress Biomarker Sensing 査読

    Jin Wang, Sota Yoshida, Masaki Ando, Kenji Sakai, Toshihiko Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2022-August   2022年

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    担当区分:筆頭著者   掲載種別:研究論文(国際会議プロシーディングス)  

    Terahertz biosensing has gained enormous attention in medical diagnosis. In this study, we demonstrated that our developed terahertz chemical microscope (TCM) could be used for sensing of small molecules such as calcium ion, stress biomarker cortisol with extremely consumption of sample solutions and high sensitivity. Calcium ion sensitive membrane and DNA aptamer were utilized for calcium ions and cortisol sensing, respectively. The approach is unique and shows great promising for creating better future healthcare.

    DOI: 10.1109/IRMMW-THz50927.2022.9895468

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  • Development of impedance measurement of lithium ion batteries electrode using terahertz chemical microscope 査読

    Masashi Shimizu, Ryoji Yamanaka, Takashi Teranishi, Jin Wang, Kenji Sakai, Keiji Tsukada, Toshihiko Kiwa

    Electrical Engineering in Japan   214 ( 4 )   2021年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Wiley  

    DOI: 10.1002/eej.23355

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    その他リンク: https://onlinelibrary.wiley.com/doi/full-xml/10.1002/eej.23355

  • Visualization of Charge-Transfer Complex for the Detection of 2, 4, 6-Trinitrotoluene Using Terahertz Chemical Microscope 査読

    Jin Wang, Hiroki Nagata, Masaki Ando, Yuichi Yoshida, Kenji Sakai, Toshihiko Kiwa

    Journal of The Electrochemical Society   168 ( 11 )   2021年11月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Electrochemical Society  

    <jats:title>Abstract</jats:title>
    <jats:p>This study focuses on the visualization of a charge-transfer complex, namely a Meisenheimer complex, for the detection of uncharged 2, 4, 6-trinitrotoluene (TNT) explosives by developing a terahertz chemical microscope (TCM) imaging system. The organic amine 3-aminopropyltriethoxysilane (APTES) was immobilized on an SiO2-film-coated TCM sensing plate, where it interacted with TNT molecules. The surface electrical potential distribution of TNT, APTES, and the charge-transfer complex was mapped. An electrical potential shift occurred due to the formation of a charge-transfer complex between the electron-rich amino-silane APTES and electron-deficient TNT molecules on the surface of the sensing plate. The electrical imaging and detection of TNT explosives by using the TCM imaging system were demonstrated by measuring the amplitude of the terahertz pulse caused by this electrical potential shift. N-(2-Aminoethyl)-3-aminopropyltrimethoxysilane and N1-(3-trimethoxysilylpropyl)diethylenetriamine were used for further evaluation and comparison of color changes arising from the amine-TNT interactions. The results have shown that TCM imaging is a promising method for the detection of uncharged TNT explosives at a low (sub-parts-per-million) concentration.</jats:p>

    DOI: 10.1149/1945-7111/ac3a2c

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  • Detection of Lung Cancer Cells in Solutions Using a Terahertz Chemical Microscope 査読 国際誌

    Yuichi Yoshida, Xue Ding, Kohei Iwatsuki, Katsuya Taniizumi, Hirofumi Inoue, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    Sensors   21 ( 22 )   7631 - 7631   2021年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:{MDPI} {AG}  

    <jats:p>Cancer genome analysis has recently attracted attention for personalized cancer treatment. In this treatment, evaluation of the ratio of cancer cells in a specimen tissue is essential for the precise analysis of the genome. Conventionally, the evaluation takes at least two days and depends on the skill of the pathologist. In our group, a terahertz chemical microscope (TCM) was developed to easily and quickly measure the number of cancer cells in a solution. In this study, an antibody was immobilized on a sensing plate using an avidin-biotin reaction to immobilize it for high density and to improve antibody alignment. In addition, as the detected terahertz signals vary depending on the sensitivity of the sensing plate, the sensitivity was evaluated using pH measurement. The result of the cancer cell detection was corrected using the result of pH measurement. These results indicate that a TCM is expected to be an excellent candidate for liquid biopsies in cancer diagnosis.</jats:p>

    DOI: 10.3390/s21227631

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  • Development of two-dimensional qualitative visualization method for isoflavones secreted from soybean roots using sheets with immobilized bovine serum albumin 査読

    Takeshi Onodera, Haruna Miyazaki, Xinzhu Li, Jin Wang, Masaru Nakayasu, Rui Yatabe, Yusuke Tahara, Ai Hosoki, Nozomu Sakurai, Akifumi Sugiyama

    Biosensors and Bioelectronics   196   113705 - 113705   2021年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier {BV}  

    DOI: 10.1016/j.bios.2021.113705

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  • Terahertz imaging technique for monitoring the flow of buffer solutions at different pH values through a microfluidic chip 査読

    Ahmed, F., Mahana, A., Taniizumi, K., Wang, J., Sakai, K., Kiwa, T.

    Japanese Journal of Applied Physics   60 ( 2 )   2021年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:IOP PUBLISHING LTD  

    Polydimethylsiloxane (PDMS)-based mold prepared using a 3D-printed structure is a cost-effective material and tool to fabricate robust microfluidic chips (MCs) without requiring expensive clean room facilities. A capillary-based MC made of PDMS can be attached onto a glass substrate to visualize the chemical reactions in different types of pH buffer solutions (BSs) flowing through microflow channels (MFCs) using terahertz (THz) image sensing technology. In this study, we designed a microfluidic structure with two inlet wells and an outlet well, equipped with a Si:sapphire substrate to visualize the chemical interaction between BSs injected at different pH values (4 and 10) through an MFC. THz imaging maps were captured during the flow of the BSs using a THz chemical microscope, and the fluid dynamics was studied. We determined and plotted the variation in the THz amplitude data with respect to the BS concentration and analyzed the characteristics of the data.

    DOI: 10.35848/1347-4065/abd86e

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  • A Simple, Rapid and Low-cost 3-Aminopropyltriethoxysilane (APTES)-based Surface Plasmon Resonance Sensor for TNT Explosive Detection 査読

    Wang, J.

    Analytical Sciences   37 ( 7 )   2021年

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)  

    DOI: 10.2116/analsci.20N028

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  • Design and validation of microfluidic parameters of a microfluidic chip using fluid dynamics 査読

    Ahmed, F., Yoshida, Y., Wang, J., Sakai, K., Kiwa, T.

    AIP Advances   11 ( 7 )   2021年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:AIP Publishing  

    The internal fluidic parameters of microfluidic channels must be analyzed to solve fundamental microfluidic problems, including microscale transport problems involving thermal analysis, chemical reactivity, velocity, pressure drop, etc., for developing good-quality chemical and biological products. Therefore, the characterization and optimization of the interaction of chemical and biological solutions through microfluidic channels are vital for fluid flow design and engineering for quality assurance in microfluidic platforms. As the internal structures and kinetics of microfluidic channels are becoming increasingly complex, experiments involving optimal fluidic and transport designs are challenging to perform with high accuracy. However, highly integrated simulation tools can guide researchers without specialized computational fluid backgrounds to design numerical prototypes of highly integrated devices. In this study, a microfluidic chip with two inlet wells and one outlet well was fabricated from polydimethylsiloxane following which simulations were performed using an ANSYS Fluent tool influenced by computational fluid dynamics at a nearly identical scale. The pressure drop and velocity profiles of the interaction of two pH buffer solutions (pH 4 and 10) through the designed microfluidic chip were qualitatively estimated from experimental data analysis and validated with the simulation results obtained from the CFD-influenced ANSYS Fluent tool. (c) 2021 Author(s).

    DOI: 10.1063/5.0056597

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  • Development of Ion Concentration Measurement Method for Minute Volume of Blood Using Terahertz Chemical Microscope 査読

    Katsuya Taniizumi, Hiroki Nagata, Masaki Ando, Atsuya Mahana, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2021-August   2021年

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    掲載種別:研究論文(国際会議プロシーディングス)  

    A terahertz chemical microscope (TCM) was proposed and developed to measure small ion concentrations in solution. By creating multiple wells on the sensing plate, it was possible to measure the ion concentration of 35 μl of whole sheep blood.

    DOI: 10.1109/IRMMW-THz50926.2021.9566818

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  • Investigation of Cross-Section Measurement Method for All-Solid-State Batteries Using Terahertz Chemical Microscopy 査読

    Masashi Shimizu, Ryota Tomie, Kashu Hamada, Takashi Teranishi, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2021-August   2021年

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    掲載種別:研究論文(国際会議プロシーディングス)  

    In recent years, all-solid-state batteries have been attracting attention as secondary batteries to replace Li ion batteries. To improve the performance of all-solid-state batteries, measurement methods are required to evaluate electrode-solid electrolyte interfaces and electrochemical reactions between electrodes. In this study, we investigated a measurement method for the cross-section of all-solid-state batteries using terahertz chemical microscopy (TCM). We fabricated a model of all-solid-state battery and showed the possibility of using TCM to measure the cross-section of the all-solid-state battery by measuring the cross-section of a model of all-solid-state battery.

    DOI: 10.1109/IRMMW-THz50926.2021.9567015

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  • Detection of cancer cells using immune reaction with a terahertz chemical microscope 査読

    Y. Yoshida, X. Ding, K. Iwatsuki, H. Inoue, J. Wang, K. Sakai, T. Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2021-August   2021年

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    掲載種別:研究論文(国際会議プロシーディングス)  

    Recently, analyzing cancer genome is attracted to personalize cancer treatment. The ratio of cancer cells in a specimen is essential for precise analysis of the genome. In our group, a terahertz chemical microscope (TCM) has been proposed and developed to measure the number of cancer cells in solution. In this study, a biotin-tagged AE1/AE3 was immobilized on a sensing plate using avidin-biotin reaction, and we succeed in detecting lung cancer cells in solutions.

    DOI: 10.1109/IRMMW-THz50926.2021.9566935

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  • Evaluation of Cosmetic Liquid Penetration Using Terahertz Time-of-Flight Method 査読

    Tomoya Niki, Tomoki Kotani, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    International Conference on Infrared, Millimeter, and Terahertz Waves, IRMMW-THz   2021-August   2021年

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    掲載種別:研究論文(国際会議プロシーディングス)  

    It is important to evaluate the penetration depth and speed of cosmetics into the skin for the cosmetic industry. However, the conventional method for measuring those parameters has some drawbacks. In this study, a terahertz time-of-flight method with Si-based emitter was applied for evaluation. The penetration of the liquid into a pig skin was measured as a travelling time of the THz pulses irradiating on a pigskin, where the glycerin concentration in the liquid was varied.

    DOI: 10.1109/IRMMW-THz50926.2021.9567484

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  • Quartz Crystal Microbalance Sensor Based on Peptide Anchored Single-Walled Carbon Nanotubes for Highly Selective TNT Explosive Detection 査読

    Jin Wang, Masayoshi Tanaka, Mina Okochi

    Proceedings of IEEE Sensors   2020-October   2020年10月

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    担当区分:筆頭著者   掲載種別:研究論文(国際会議プロシーディングス)  

    In this study, quartz crystal microbalance (QCM) sensor based on 2, 4, 6-trinitrotoluene (TNT) recognition peptide functionalized single-walled carbon nanotubes (SWCNTs) for TNT explosive detection was developed. The SWCNTs were immobilized on the self-assembled monolayer (SAM) cysteamine modified QCM gold-chip surface. Through π-stacking interaction, the specific TNT recognition peptide (named TNTHCDR3) was anchored on the SWCNTs surface. The results revealed that the peptide-SWCNTs hybrid modified QCM sensor offered highly selective detection of TNT explosive.

    DOI: 10.1109/SENSORS47125.2020.9278670

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  • Peptide-modified Microelectrode-based Potentiometric Device for 2,4,6-trinitrotoluene Molecule Detection 査読

    Jin Wang

    Sensors and Materials   31 ( 3 )   2609 - 2617   2019年8月

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:MYU, SCIENTIFIC PUBLISHING DIVISION  

    A 2,4,6-trinitrotoluene (TNT) molecule recognition peptide-modified potentiometric device was developed in a multiparallel way using microelectrodes. The change in potential caused by the explosive target and recognition peptide was monitored in real-time sensorgrams through our laboratory-built analysis system. The peptide-modified microelectrode-based potentiometric device demonstrated the highly selective and sensitive sensing of the TNT molecule over other aromatic analogues.

    DOI: 10.18494/sam.2019.2385

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  • An SPR sensor chip based on peptide-modified single-walled carbon nanotubes with enhanced sensitivity and selectivity in the detection of 2,4,6-trinitrotoluene explosives 査読 国際誌

    Wang, J., Du, S., Onodera, T., Yatabe, R., Tanaka, M., Okochi, M., Toko, K.

    Sensors (Switzerland)   18 ( 12 )   2018年

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    In this study, we developed a surface plasmon resonance (SPR) sensor chip based on 2,4,6-trinitrotoluene (TNT) recognition peptide-modified single-walled carbon nanotubes (SWCNTs). The carboxylic acid-functionalized SWCNTs were immobilized on a 3-aminopropyltriethoxysilane (APTES)-modified SPR Au chip surface. Through π-stacking between the aromatic amino acids and SWCNTs, the TNT recognition peptide TNTHCDR3 was immobilized onto the surface of the SWCNTs. The peptide⁻SWCNTs-modified sensor surface was confirmed and evaluated by atomic force microscope (AFM) observation. The peptide⁻SWCNTs hybrid SPR sensor chip exhibited enhanced sensitivity with a limit of detection (LOD) of 772 ppb and highly selective detection compared with commercialized carboxymethylated dextran matrix sensor chips.

    DOI: 10.3390/s18124461

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  • Highly Selective Rational Design of Peptide-Based Surface Plasmon Resonance Sensor for Direct Determination of 2,4,6-trinitrotoluene (TNT) Explosive 査読

    Wang, J., Muto, M., Yatabe, R., Tahara, Y., Onodera, T., Tanaka, M., Okochi, M., Toko, K.

    Sensors and Actuators, B: Chemical   264   279 - 284   2018年

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE SA  

    In this study, 2,4,6-trinitrotoluene (TNT) binding peptide was synthesized and screened for TNT specific detection using surface plasmon resonance (SPR) sensor. The TNT binding peptide was rational design and synthesized through amino acid sequence from complementarity determining region (CDR) in the anti-TNT monoclonal antibody, which was produced from hybridoma cell using TNP-KLH conjugate as antigen. Three TNT binding peptide sequences were obtained from the heavy chain of CDR1 named TNTHCDRI, TNTHCDR2 from CDR2 and TNTHCDR3 from CDR3 of anti-TNT antibody. Screening process of three candidate peptides were carried out by using the SPR sensor with direct determination, which the peptide was directly immobilized on the sensor chip CM7 surface through amine coupling reaction. The results demonstrated that peptide TNTHCDR3 was determined as TNT binding peptide and no nonspecific binding was observed. The selectivity of TNT binding peptide TNTHCDR3 was also testified by six kinds of TNT analogues. The results indicated the specific binding between TNT and peptide TNTHCDR3. (C) 2018 Elsevier B.V. All rights reserved.

    DOI: 10.1016/j.snb.2018.02.075

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  • Near infrared optical biosensor based on peptide functionalized single-walled carbon nanotubes hybrids for 2,4,6-trinitrotoluene (TNT) explosive detection 査読

    Wang, J.

    Analytical Biochemistry   550   2018年

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    担当区分:筆頭著者, 責任著者   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.ab.2018.04.011

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  • Array-Based Rational Design of Short Peptide Probe-Derived from an Anti-TNT Monoclonal Antibody 査読 国際誌

    Okochi, M., Muto, M., Yanai, K., Tanaka, M., Onodera, T., Wang, J., Ueda, H., Toko, K.

    ACS Combinatorial Science   19 ( 10 )   625 - 632   2017年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Complementarity-determining regions (CDRs) are sites on the variable chains of antibodies responsible for binding to specific antigens. In this study, a short peptide probe for recognition of 2,4,6-trinitrotoluene (TNT), was identified by testing sequences derived from the CDRs of an anti-TNT monoclonal antibody. The major TNT-binding site in this antibody was identified in the heavy chain CDR3 by antigen docking simulation and confirmed by an immunoassay using a spot-synthesis based peptide array comprising amino acid sequences of six CDRs in the variable region. A peptide derived from heavy chain CDR3 (RGYSSFIYWF) bound to TNT with a dissociation constant of 1.3 μM measured by surface plasmon resonance. Substitution of selected amino acids with basic residues increased TNT binding while substitution with acidic amino acids decreased affinity, an isoleucine to arginine change showed the greatest improvement of 1.8-fold. The ability to create simple peptide binders of volatile organic compounds from sequence information provided by the immune system in the creation of an immune response will be beneficial for sensor developments in the future.

    DOI: 10.1021/acscombsci.7b00035

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  • Rational design of peptide-functionalized surface plasmon resonance sensor for specific detection of TNT explosive 査読 国際誌

    Wang, J., Muto, M., Yatabe, R., Onodera, T., Tanaka, M., Okochi, M., Toko, K.

    Sensors (Switzerland)   17 ( 10 )   2017年

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    担当区分:筆頭著者, 責任著者   記述言語:英語   掲載種別:研究論文(学術雑誌)  

    In this study, a rationally-designed 2,4,6-trinitrotoluene (TNT) binding peptide derived from an amino acid sequence of the complementarity-determining region (CDR) of an anti-TNT monoclonal antibody was used for TNT detection based on a maleimide-functionalized surface plasmon resonance (SPR) sensor. By antigen-docking simulation and screening, the TNT binding candidate peptides were obtained as TNTHCDR1 derived from the heavy chain of CDR1, TNTHCDR2 derived from CDR2, and TNTHCDR3 from CDR3 of an anti-TNT antibody. The binding events between candidate peptides and TNT were evaluated using the SPR sensor by direct determination based on the 3-aminopropyltriethoxysilane (APTES) surface. The TNT binding peptide was directly immobilized on the maleimide-functionalized sensor chip surface from N-γ-maleimidobutyryl-oxysuccinimide ester (GMBS). The results demonstrated that peptide TNTHCDR3 was identified and selected as a TNT binding peptide among the other two candidate peptides. Five kinds of TNT analogues were also investigated to testify the selectivity of TNT binding peptide TNTHCDR3. Furthermore, the results indicated that the APTES-GMBS-based SPR sensor chip procedure featured a great potential application for the direct detection of TNT.

    DOI: 10.3390/s17102249

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  • A micro IrOx potentiometric sensor for direct determination of organophosphate pesticides 査読

    Wang, J., Yokokawa, M., Satake, T., Suzuki, H.

    Sensors and Actuators, B: Chemical   220   2015年

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.snb.2015.05.115

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  • Microfluidic Device for Coulometric Detection of Organophosphate Pesticides 査読

    WANG Jin, SATAKE Takaaki, SUZUKI Hiroaki

    Analytical Sciences   31 ( 7 )   591 - 595   2015年

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    担当区分:筆頭著者   記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:The Japan Society for Analytical Chemistry  

    A microdevice for coulometric detection of organophosphate pesticides (OPs) was fabricated based on the measurement of the inhibition of an enzyme, acetylcholinesterase (AChE), by OPs. Thiocholine (TCh) produced in the enzymatic reaction of AChE with acetylthiocholine (ATCh) as a substrate was oxidized on a microelectrode array formed in a main flow channel. Volumes of plugs of necessary solutions were measured using a structure consisting of a row of rhombuses formed in an auxiliary flow channel. The plugs were merged and solution components were mixed at a T-junction formed with the main and auxiliary flow channels. A linear relationship was confirmed between the generated charge and the logarithm of the OP (malathion) concentration in a concentration range between 10−6 and 10−3 M with a correlation coefficient of 0.951. The lower limit of detection was 412 nM.

    DOI: 10.2116/analsci.31.591

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  • Coulometric microdevice for organophosphate pesticide detection 査読

    Wang, J., Suzuki, H., Satake, T.

    Sensors and Actuators, B: Chemical   204   2014年

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.snb.2014.06.115

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  • The effects on fruit and vegetable by ultra-high pressure technology 査読

    Jin Wang

    Food Research and Development   2012年

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    担当区分:筆頭著者   掲載種別:研究論文(学術雑誌)  

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MISC

  • 神経伝達物質を検知するテラヘルツ波バイオセンサーの開発 査読

    森田 滉生, 吉田 聡太, 光田 祐太, 逢坂 大樹, 笠原 真悟, 王 璡, 紀和 利彦

    2023年11月

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    担当区分:責任著者  

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  • フレキシブル超薄膜水素センサの開発 査読

    王 裕基, 若林 翔貴, 王 璡, 紀和 利彦

    2023年11月

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  • Comparative Study of Terahertz Chemical Microscopy and Flexible ISFET Approaches for Calcium Ion Detection 査読

    Sota Yoshida, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    2023 48th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)   2023年9月

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    出版者・発行元:IEEE  

    In this study, we conducted a comprehensive comparison of two advanced techniques, terahertz chemical microscopy (TCM) and ion-sensitive field-effect transistors (ISFET), for calcium ion detection. The results revealed the advantages and limitations of TCM and flexible ISFET, offering valuable insights into their applications and improvements.

    DOI: 10.1109/irmmw-thz57677.2023.10299237

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  • Detection of Nucleocapsid Proteins of COVID-19 using a Terahertz Chemical Microscope 査読

    Xue Ding, Sayaka Tsuji, Mana Murakami, Jin Wang, Hirofumi Inoue, Toshihiko Kiwa

    2023 48th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)   2023年9月

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    出版者・発行元:IEEE  

    Since the first person infected with COVID-19 was diagnosed in December 2019, the infection has spread rapidly all over the world. PCR and antigen testing are commonly used to detect infection, but detection sensitivity and sample size can be improved. In our group, a terahertz chemical microscope (TCM) has been developed. In this study, we successfully detected the SARS-CoV-2 nucleocapsid proteins (N protein) in solutions by immobilizing the aptamer and N protein on a sensing plate using avidin-biotin reaction.

    DOI: 10.1109/irmmw-thz57677.2023.10298956

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  • Electric Potential Mapping Measurement for All-Solid-State Lithium-Ion Batteries using a Terahertz Chemical Microscope 査読

    Taketo Yamaguchi, Yusei Hosokawa, Ryota Tomie, Takumi Higuchi, Takashi Teranishi, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    2023 48th International Conference on Infrared, Millimeter, and Terahertz Waves (IRMMW-THz)   2023年9月

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    出版者・発行元:IEEE  

    Terahertz Chemical Microscope (TCM) has been developed to measure the electric potential distribution of batteries during charging and discharging. The battery is mounted on a sensing plate with SiO2 and Si films on a sapphire substrate and irradiate with a femtosecond laser to generate THz pulses. THz amplitude is proportional to the electric potential on the sensing plate, so the electric potential distribution of the battery on the sensing plate can be measured. In this study, a method was developed to measure the cathode surface of an all-solid-state lithium ion battery by the TCM and visualized the electric potential distribution of the battery. This result shows that the TCM could be a useful tool for measuring of all-solid-state batteries.

    DOI: 10.1109/irmmw-thz57677.2023.10299081

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  • Visvcosity measurement of biological solvents using HTS-SQUID with magnetic nanoparticles

    K Yamashita, S Asayama, R Moriya, T Yamanoto, W Jin, T Kiwa

    2023年8月

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    掲載種別:機関テクニカルレポート,技術報告書,プレプリント等  

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  • テラヘルツ波ケミカル顕微鏡を用いたアプタマーによるSARS-CoV-2検出技術の開発

    辻紗也佳, DING Xue, 村上真菜, 井上博文, WANG Jin, 堺健司, 紀和利彦

    応用物理学会春季学術講演会講演予稿集(CD-ROM)   70th   2023年

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  • Electric Potential Mapping of All-Solid-State Lithium Ion Batteries using A Terahertz Chemical Microscope 査読

    Ryota Tomie, Taketo Yamaguchi, Masashi Shimizu, Kashu Hamada, Takashi Teranishi, Hidetoshi Nose, Masaki Kobayashi, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)   2022-August   2022年8月

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    出版者・発行元:IEEE  

    A terahertz (THz) chemical microscope has been developed to measure the electric potential distribution of liquid phase lithium ion batteries (LIBs) during charging and discharging. A LIB was fabricated on a sensing plate, which consists of SiO2 and Si films on a sapphire substrate, to generate THz pulses by a laser irradiation. Since the amplitude of THz is proportional to the electric potential on the sensing plate, the electric potential distribution of the lithium ion battery on the sensing plate could be visualized. In this study, the electric potential distribution across a conventional all-solid-state LIB was measured by immobilizing the LIB on the sensing plate using epoxy resin. The distribution of the electric potentials of the battery was clearly visualized by the TCM. This result indicates that the TCM could be one of useful tools for the development high performance batteries.

    DOI: 10.1109/irmmw-thz50927.2022.9896121

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  • Terahertz Chemical Microscope for Calcium Ions and Stress Biomarker Sensing 査読

    Jin Wang, Sota Yoshida, Masaki Ando, Kenji Sakai, Toshihiko Kiwa

    2022 47th International Conference on Infrared, Millimeter and Terahertz Waves (IRMMW-THz)   2022-August   2022年8月

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    担当区分:筆頭著者, 責任著者   出版者・発行元:IEEE  

    Terahertz biosensing has gained enormous attention in medical diagnosis. In this study, we demonstrated that our developed terahertz chemical microscope (TCM) could be used for sensing of small molecules such as calcium ion, stress biomarker cortisol with extremely consumption of sample solutions and high sensitivity. Calcium ion sensitive membrane and DNA aptamer were utilized for calcium ions and cortisol sensing, respectively. The approach is unique and shows great promising for creating better future healthcare.

    DOI: 10.1109/irmmw-thz50927.2022.9895468

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  • Study on the Performance of Sensitive Part of Bridge Type Ultra-Thin Film Hydrogen Sensor 査読

    Takahiro Mori, Shoki Wakabayashi, Kenji Kondoh, Takuya Takahashi, Makoto Nakagawa, Naohiro Ueda, Jin Wang, Kenji Sakai, Keiji Tsukada, Toshihiko Kiwa

    2021年11月

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    掲載種別:記事・総説・解説・論説等(国際会議プロシーディングズ)  

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  • Detection of Proteins Associated with Alzheimer’s Disease using a Terahertz Chemical Microscope 査読

    Kohei Iwatsuki, Yuichi Yoshida, Xue Ding, Sayaka Tsuji, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    2021年11月

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    掲載種別:記事・総説・解説・論説等(国際会議プロシーディングズ)  

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  • Investigation of Cross-Section Measurement Method for All-Solid-State Batteries Using Terahertz Chemical Microscopy 査読

    Masashi Shimizu, Ryota Tomie, Kashu Hamada, Takashi Teranishi, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    2021-August   2021年11月

  • Evaluation of Cosmetic Liquid Penetration Using Terahertz Time-of-Flight Method 査読

    Tomoya Niki, Tomoki Kotani, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    2021-August   2021年11月

  • Detection of cancer cells using immune reaction with a terahertz chemical microscope 査読

    Y Yoshida, X Ding, K Iwatsuki, H Inoue, J Wang, K Sakai, T Kiwa

    Part F146-JSAP 2019   2021年11月

  • Development of Ion Concentration Measurement Method for Minute Volume of Blood Using Terahertz Chemical Microscope 査読

    Katsuya Taniizumi, Hiroki Nagata, Masaki Ando, Atsuya Mahana, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    2021-August   2021年11月

  • Signal Accuracy of Terahertz Chemical Microscope for Lung Cancer Cell Detection 査読

    Yuichi Yoshida, Xue Ding, Kohei Iwatsuki, Sayaka Tsuji, Hirofumi Inoue, Jin Wang, Kenji Sakai, Toshihiko Kiwa

    2021年11月

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    掲載種別:記事・総説・解説・論説等(国際会議プロシーディングズ)  

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  • Terahertz Chemical Microscope Imaging System for 2, 4, 6-Trinitrotoluene Detection 査読

    Jin WANG, Hiroki Nagata, Kenji Sakai, Keiji Tsukada, Toshihiko Kiwa

    2021年10月

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    担当区分:筆頭著者, 責任著者   掲載種別:記事・総説・解説・論説等(国際会議プロシーディングズ)  

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  • 局所領域の電気化学インピーダンス評価に向けたHTS-SQUIDによる微小領域磁場計測装置の開発

    堺健司, 青木良太, WANG Jin, 紀和利彦, 塚田啓二

    応用物理学会春季学術講演会講演予稿集(CD-ROM)   68th   2021年

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  • テラヘルツ波ケミカル顕微鏡を用いたリチウムイオン電池電極のインピーダンス測定法の開発

    清水雅司, 山中亮治, 寺西貴志, Wang Jin, 堺健司, 塚田啓二, 紀和利彦

    電気学会論文誌 E   141 ( 8 )   2021年

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  • ブリッジ型Pt超薄膜水素センサの感応部形状の検討

    森貴啓, 小部寛斗, WANG Jin, 堺健司, 塚田啓二, 紀和利彦, 近藤健二, 高橋琢哉, 中川眞, 上田尚宏

    電気学会全国大会講演論文集(CD-ROM)   2021   2021年

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  • pH測定を利用したセンサ感度の補正によるがん細胞の検出信頼性の向上

    葭田勇一, XUE Ding, 岩附康平, 井上博文, WANG Jin, 堺健司, 紀和利彦

    電気・情報関連学会中国支部連合大会講演論文集(CD-ROM)   72nd   2021年

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  • Quartz crystal microbalance sensor based on peptide anchored single-walled carbon nanotubes for highly selective TNT explosive detection 査読

    2020-October   2020年10月

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    担当区分:筆頭著者, 責任著者  

    DOI: 10.1109/SENSORS47125.2020.9278670

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  • ウシ血清アルブミン固定化シートを用いたダイズ根圏のダイゼインの可視化

    小野寺武, 宮崎春菜, LI Xinzhu, WANG Jin, 矢田部塁, 田原祐助, 細木藍, 桜井望, 杉山暁史

    電気学会研究会資料   ( CHS-20-011-018 )   2020年

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  • ウシ血清アルブミンを用いたダイズ根のダイゼイン分泌分布計測システムの開発

    宮崎春菜, LI Xinzhu, WANG Jin, 矢田部塁, 田原祐助, 細木藍, 櫻井望, 杉山暁史, 小野寺武

    電気学会全国大会講演論文集(CD-ROM)   2020   2020年

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  • 多種多様な自動車の磁気ノイズの特性評価

    齊藤大介, 林実, 王しん, 堺健司, 紀和利彦, 塚田啓二

    日本磁気学会学術講演概要集   44th   2020年

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  • 根圏ダイゼイン検出のためのポリクローナル抗体の作製と表面プラズモン共鳴免疫センサによる評価

    鯵坂大樹, WANG Jin, LI Xinzhu, 矢田部塁, 田原祐助, 細木藍, 桜井望, 杉山暁史, 小野寺武

    電気学会研究会資料   ( CHS-19-013-029 )   2019年

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  • ウシ血清アルブミンの蛍光を用いた大豆根圏のダイゼイン計測シートの開発

    LI Xinzhu, WANG Jin, 矢田部塁, 田原祐助, 鰺坂大樹, 細木藍, 桜井望, 杉山暁史, 小野寺武

    センサ・マイクロマシンと応用システムシンポジウム(CD-ROM)   36th   2019年

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  • 爆発物検出に向けた抗体由来の分子認識ペプチドの探索

    矢内健太郎, 武藤正記, 武藤正記, WANG Jin, WANG Jin, 田中祐圭, 田中祐圭, 上田宏, 小野寺武, 小野寺武, 都甲潔, 都甲潔, 大河内美奈, 大河内美奈

    化学工学会年会研究発表講演要旨集(CD-ROM)   82nd   2017年

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  • 爆発物検出センサの開発に向けた抗体アミノ酸配列に基づく認識プローブの設計

    武藤正記, 武藤正記, 矢内健太郎, 矢内健太郎, WANG Jin, WANG Jin, 田中祐圭, 田中祐圭, 上田宏, 小野寺武, 小野寺武, 都甲潔, 都甲潔, 大河内美奈, 大河内美奈

    化学とマイクロ・ナノシステム学会研究会講演要旨集   33rd   2016年

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  • ペプチドアレイを用いた抗体由来TNT結合ペプチドの配列最適化

    矢内健太郎, 矢内健太郎, 武藤正記, 武藤正記, WANG Jin, WANG Jin, 田中祐圭, 田中祐圭, 上田宏, 小野寺武, 小野寺武, 都甲潔, 都甲潔, 大河内美奈, 大河内美奈

    化学工学会年会研究発表講演要旨集(CD-ROM)   81st   2016年

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  • 抗TNT抗体の相補性決定領域に基づいた爆発物認識ペプチドの開発

    武藤正記, 武藤正記, 矢内健太郎, 矢内健太郎, WANG Jin, WANG Jin, 田中祐圭, 田中祐圭, 上田宏, 小野寺武, 小野寺武, 都甲潔, 都甲潔, 大河内美奈, 大河内美奈

    電気化学会大会講演要旨集(CD-ROM)   83rd   2016年

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  • 抗体相補性決定領域に基づいた揮発性爆発化合物の特異的ペプチドプローブの開発

    武藤正記, 武藤正記, 矢内健太郎, 矢内健太郎, 田中祐圭, 田中祐圭, 上田宏, WANG Jin, WANG Jin, 小野寺武, 小野寺武, 都甲潔, 都甲潔, 大河内美奈, 大河内美奈

    日本生物工学会大会講演要旨集   68th   2016年

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産業財産権

  • 特開2022-065994 根圏ケミカル濃度分布可視化シート

    小野寺 武, 王 璡, 李 心竹, 宮▲崎▼ 春菜, 矢田部 塁, 田原 祐助

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    出願番号:特願2020-174861 

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受賞

  • 公益財団法人池谷科学技術振興財団 単年度研究助成

    2023年6月  

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  • 岡山県産業振興財団科学技術賞

    2022年7月   公益財団法人岡山工学振興会  

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  • Best Teacher Award

    2021年3月   岡山大学工学部  

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  • 公益財団法人 岡山工学振興会科学技術賞

    2020年7月  

    王 璡

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  • 若手研究者優秀論文賞 2019年度

    2020年4月   Sensors and Materials MYU K.K.  

    Jin Wang

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  • 論文賞

    2017年9月   MDPI Sensors  

    Jin Wang

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  • 優秀発表賞

    2013年9月   筑波大学  

    Jin Wang

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共同研究・競争的資金等の研究

  • AuNPs and DNA Aptamer-Driven Terahertz Sensor for Highly Sensitive Detection of Small Molecules

    研究課題/領域番号:24K07524  2024年04月 - 2027年03月

    日本学術振興会  科学研究費助成事業  基盤研究(C)

    WANG JIN

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    配分額:4680000円 ( 直接経費:3600000円 、 間接経費:1080000円 )

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  • 神経伝達物質の可視化のためのDNAアプタマー/SWCNTハイブリットプローブの開発

    2023年04月 - 2024年03月

    公益財団法人池谷科学技術振興財団 研究助成 

    王 璡

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    担当区分:研究代表者 

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  • テラヘルツ波ケミカル顕微鏡によるがんバイオマーカーの高感度検出

    2022年06月 - 2023年03月

    公益財団法人岡山工学振興会 

    王璡

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    担当区分:研究代表者 

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  • Computational design of recognition peptide based plasmonic biosensor for small molecules detection

    研究課題/領域番号:21K14169  2021年04月 - 2024年03月

    日本学術振興会  科学研究費助成事業 若手研究  若手研究

    WANG JIN

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    配分額:4680000円 ( 直接経費:3600000円 、 間接経費:1080000円 )

    This research focuses on developing peptide recognition elements for small volatile organic molecules detection, which are diseased-related compounds. Benzaldehyde and acetone binding peptides have been derived from the odorant binding protein. Through molecular docking and simulation, the binding pocket and residues are determined. The amino acids SER and GLN played an important role in interaction with
    benzaldehyde by forming hydrogen bond and THR with acetone.

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  • テラヘルツ波を用いた TNT 爆薬イメージセンサーの開発

    2020年06月 - 2021年03月

    公益財団法人岡山工学振興会 

    王璡

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    担当区分:研究代表者 

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担当授業科目

  • エネルギー・エレクトロニクス実験A (2023年度) 3・4学期  - 水3~7

  • ヘルスシステム統合科学アドバンストインターンシップ (2023年度) 通年  - その他

  • ヘルスシステム統合科学専門英語 (2023年度) 後期  - その他

  • ヘルスシステム統合科学特別研究 (2023年度) 通年  - その他

  • ヘルスシステム統合科学特別研究 (2023年度) 通年  - その他

  • 工学基礎実験実習 (2023年度) 1・2学期  - その他

  • 工学基礎実験実習 (2023年度) 1・2学期  - 火5~8

  • 工学基礎実験実習 (2023年度) 1・2学期  - 火5~8

  • エネルギー・エレクトロニクス実験A (2022年度) 3・4学期  - 水2~6

  • ネットワーク工学実験A (2022年度) 3・4学期  - 水2~6

  • ヘルスシステム統合科学専門英語 (2022年度) 後期  - その他

  • ヘルスシステム統合科学特別研究 (2022年度) 通年  - その他

  • 工学基礎実験実習 (2022年度) 1・2学期  - その他

  • 工学基礎実験実習 (2022年度) 1・2学期  - 火5~8

  • 工学基礎実験実習 (2022年度) 1・2学期  - 火5~8

  • 電気通信系実験B (2022年度) 3・4学期  - その他

  • ヘルスシステム統合科学特別研究 (2021年度) 通年  - その他

  • 工学基礎実験実習 (2021年度) 1・2学期  - その他

  • 工学基礎実験実習 (2021年度) 1・2学期  - 火5,火6,火7,火8

  • 電気通信系実験B (2021年度) 3・4学期  - 水2,水3,水4,水5,水6

  • 工学基礎実験実習 (2020年度) 1・2学期  - 火4,火5,火6,火7

  • 工学基礎実験実習 (2020年度) 1・2学期  - 火4,火5,火6,火7

  • 電気通信系実験B (2020年度) 3・4学期  - 水2,水3,水4,水5,水6

  • 電気通信系実験Ⅱ (2020年度) 3・4学期  - 水2,水3,水4,水5,水6

▼全件表示

 

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