研究者詳細 - 江國　大輔

論文 - 江國　大輔

分割表示 163 件中 21 - 40 件目／全件表示 >>

Features of the oral microbiome in Japanese elderly people with 20 or more teeth and a non-severe periodontal condition during periodontal maintenance treatment: A cross-sectional study. 査読国際誌

Naoki Toyama, Daisuke Ekuni, Aya Yokoi, Daiki Fukuhara, Md Monirul Islam, Nanami Sawada, Yukiho Nakashima, Momoko Nakahara, Ichiro Sumita, Manabu Morita

Frontiers in cellular and infection microbiology 12 957890 - 957890 2022年

記述言語：英語掲載種別：研究論文（学術雑誌）

INTRODUCTION: The aim of the present study was to characterize the profile and diversity of the oral microbiome of a periodontally non-severe group with ≥20 teeth in comparison with a severe periodontitis group of elderly Japanese people. METHODS: A total of 50 patients who had ≥20 teeth and aged ≥60 years were recruited, and 34 participants (13 non-severe participants) were analyzed. After oral rinse (saliva after rinsing) sample collection, the V3-V4 regions of the 16S rRNA gene were sequenced to investigate microbiome composition, alpha diversity (Shannon index, Simpson index, richness, and evenness), and beta diversity using principal coordinate analysis (PCoA) based on weighted and unweighted UniFrac distances. A linear discriminant analysis effect size was calculated to identify bacterial species in the periodontally non-severe group. RESULTS: The periodontally non-severe group showed lower alpha diversity than that of the severe periodontitis group (p <0.05); however, the beta diversities were not significantly different. A higher relative abundance of four bacterial species (Prevotella nanceiensis, Gemella sanguinis, Fusobacterium periodonticum, and Haemophilus parainfluenzae) was observed in the non-severe group than that in the severe periodontitis group. CONCLUSION: The oral microbiome in elderly Japanese people with ≥20 teeth and a non-severe periodontal condition was characterized by low alpha diversity and the presence of four bacterial species.

DOI： 10.3389/fcimb.2022.957890

PubMed

researchmap

Association between Self-Reported Chewing Status and Glycemic Control in Japanese Adults. 査読国際誌

Komei Iwai, Tetsuji Azuma, Takatoshi Yonenaga, Daisuke Ekuni, Kazutoshi Watanabe, Akihiro Obora, Fumiko Deguchi, Takao Kojima, Manabu Morita, Takaaki Tomofuji

International journal of environmental research and public health 18 ( 18 ) 2021年9月

Detection of Salivary miRNAs That Predict Chronic Periodontitis Progression: A Cohort Study. 査読国際誌

Kohei Fujimori, Toshiki Yoneda, Takaaki Tomofuji, Daisuke Ekuni, Tetsuji Azuma, Takayuki Maruyama, Yoshio Sugiura, Manabu Morita

International journal of environmental research and public health 18 ( 15 ) 2021年7月

Comprehensive Analysis of Risk Factors for Periodontitis Focusing on the Saliva Microbiome and Polymorphism. 査読国際誌

Naoki Toyama, Daisuke Ekuni, Daisuke Matsui, Teruhide Koyama, Masahiro Nakatochi, Yukihide Momozawa, Michiaki Kubo, Manabu Morita

International journal of environmental research and public health 18 ( 12 ) 2021年6月

Parafunctional masseter muscle activity during waking is related to periodontitis progression: A pilot prospective cohort study. 査読国際誌

Daisuke Ekuni, Seiya Kato, Shigehisa Kawakami, Takayuki Maruyama, Kota Kataoka, Yoko Uchida-Fukuhara, Daiki Fukuhara, Naoki Toyama, Aya Yokoi, Md Monirul Islam, Subrina Binta Khair, Naoki Kodama, Manabu Morita

Journal of clinical periodontology 48 ( 6 ) 785 - 794 2021年6月

「口臭による日常生活への支障」に関連する要因査読

佐保輝, 横井彩, 丸山貴之, 竹内倫子, 江國大輔, 森田学

日本口臭学会会誌 12 ( 1 ) 11 - 17 2021年5月

基本チェックリストの口腔機能3項目と口腔機能との関連

竹内倫子, 澤田ななみ, 鷲尾憲文, 澤田弘一, 江國大輔, 森田学

老年歯科医学 35 ( 4 ) 317 - 318 2021年3月

若年者と高齢者との間での口腔機能の比較

澤田ななみ, 竹内倫子, 江國大輔, 森田学

老年歯科医学 35 ( 4 ) 363 - 364 2021年3月

Association between the incidence of early childhood caries and attending childcare among toddlers in a rural area of Japan: a prospective cohort study. 国際誌

Aya Yokoi, Noriko Takeuchi, Daisuke Ekuni, Manabu Morita

Acta odontologica Scandinavica 79 ( 2 ) 118 - 123 2021年3月

Oral diadochokinesis is related to decline in swallowing function among community-dwelling Japanese elderly: a cross-sectional study. 国際誌

Noriko Takeuchi, Nanami Sawada, Daisuke Ekuni, Manabu Morita

Aging clinical and experimental research 33 ( 2 ) 399 - 405 2021年2月

Living with Family Is Directly Associated with Regular Dental Checkup and Indirectly Associated with Gingival Status among Japanese University Students: A 3-Year Cohort Study. 査読国際誌

Momoko Nakahara, Daisuke Ekuni, Kota Kataoka, Aya Yokoi, Yoko Uchida-Fukuhara, Daiki Fukuhara, Terumasa Kobayashi, Naoki Toyama, Hikari Saho, Md Monirul Islam, Yoshiaki Iwasaki, Manabu Morita

International journal of environmental research and public health 18 ( 1 ) 324 - 324 2021年1月

Living with Family Is Directly Associated with Regular Dental Checkup and Indirectly Associated with Gingival Status among Japanese University Students: A 3-Year Cohort Study. 国際誌

Momoko Nakahara, Daisuke Ekuni, Kota Kataoka, Aya Yokoi, Yoko Uchida-Fukuhara, Daiki Fukuhara, Terumasa Kobayashi, Naoki Toyama, Hikari Saho, Md Monirul Islam, Yoshiaki Iwasaki, Manabu Morita

International journal of environmental research and public health 18 ( 1 ) 2021年1月

記述言語：英語掲載種別：研究論文（学術雑誌）

Although some studies showed that lifestyle was associated with oral health behavior, few studies investigated the association between household type and oral health behavior. The aim of this prospective cohort study was to investigate the association between household type, oral health behavior, and periodontal status among Japanese university students. Data were obtained from 377 students who received oral examinations and self-questionnaires in 2016 and 2019. We assessed periodontal status using the percentage of bleeding on probing (%BOP), probing pocket depth, oral hygiene status, oral health behaviors, and related factors. We used structural equation modeling to determine the association between household type, oral health behaviors, gingivitis, and periodontitis. At follow-up, 252 students did not live with their families. The mean ± standard deviation of %BOP was 35.5 ± 24.7 at baseline and 32.1 ± 25.3 at follow-up. In the final model, students living with their families were significantly more likely to receive regular dental checkup than those living alone. Regular checkup affected the decrease in calculus. The decrease in calculus affected the decrease in %BOP over 3 years. Living with family was directly associated with regular dental checkups and indirectly contributed to gingival status among Japanese university students.

DOI： 10.3390/ijerph18010324

PubMed

researchmap

Association between Household Exposure to Secondhand Smoke and Dental Caries among Japanese Young Adults: A Cross-Sectional Study. 査読国際誌

Hikari Saho, Ayano Taniguchi-Tabata, Daisuke Ekuni, Aya Yokoi, Kouta Kataoka, Daiki Fukuhara, Naoki Toyama, Md Monirul Islam, Nanami Sawada, Yukiho Nakashima, Momoko Nakahara, Junya Deguchi, Yoko Uchida-Fukuhara, Toshiki Yoneda, Yoshiaki Iwasaki, Manabu Morita

International journal of environmental research and public health 17 ( 22 ) 8623 - 8623 2020年11月

Association between Household Exposure to Secondhand Smoke and Dental Caries among Japanese Young Adults: A Cross-Sectional Study. 国際誌

International journal of environmental research and public health 17 ( 22 ) 2020年11月

記述言語：英語掲載種別：研究論文（学術雑誌）

The long-term effects of secondhand smoke (SHS) on dental caries among Japanese young adults remain unclear. The purpose of this cross-sectional study was to evaluate whether household exposure to SHS is associated with dental caries in permanent dentition among Japanese young adults. The study sample included 1905 first-year university students (age range: 18-19 years) who answered a questionnaire and participated in oral examinations. The degree of household exposure to SHS was categorized into four levels according to the SHS duration: no experience (-), past, current SHS < 10 years, and current SHS ≥ 10 years. Dental caries are expressed as the total number of decayed, missing, and filled teeth (DMFT) score. The relationships between SHS and dental caries were determined by logistic regression analysis. DMFT scores (median (25th percentile, 75th percentile)) were significantly higher in the current SHS ≥ 10 years (median: 1.0 (0.0, 3.0)) than in the SHS-(median: 0.0 (0.0, 2.0)); p = 0.001). DMFT ≥ 1 was significantly associated with SHS ≥ 10 years (adjusted odds ratio: 1.50, 95% confidence interval: 1.20-1.87, p < 0.001). Long-term exposure to SHS (≥10 years) was associated with dental caries in permanent dentition among Japanese young adults.

DOI： 10.3390/ijerph17228623

PubMed

researchmap

若年者と高齢者との間での口腔機能の比較

澤田ななみ, 竹内倫子, 江國大輔, 森田学

日本老年歯科医学会総会・学術大会プログラム・抄録集 31回 130 - 130 2020年11月

基本チェックリストの口腔機能3項目と口腔機能との関連

竹内倫子, 澤田ななみ, 鷲尾憲文, 澤田弘一, 江國大輔, 森田学

日本老年歯科医学会総会・学術大会プログラム・抄録集 31回 102 - 102 2020年11月

高校生におけるDMF歯数の増加と口腔保健行動との関連

澤田ななみ, 竹内倫子, 田畑綾乃, 江國大輔, 森田学

口腔衛生学会雑誌 70 ( 4 ) 190 - 195 2020年10月

福祉施設利用高齢者における日常生活自立度と口腔機能との関係

中島千穂, 竹内倫子, 江國大輔, 森田学

口腔衛生学会雑誌 70 ( 4 ) 215 - 221 2020年10月

1歳6ヵ月児および2歳6ヵ月児におけるう蝕発生要因の比較

竹内倫子, 江國大輔, 外山直樹, 森田学

日本公衆衛生学会総会抄録集 79回 367 - 367 2020年10月

Horseradish peroxidase interacts with the cell wall peptidoglycans on oral bacteria. 査読国際誌

Hirofumi Mizuno, Eiji Takayama, Ayano Satoh, Takeshi Into, Masanori Adachi, Daisuke Ekuni, Koji Yashiro, Masako Mizuno-Kamiya, Motohiko Nagayama, Seitaro Saku, Takaaki Tomofuji, Yutaka Doi, Yukitaka Murakami, Nobuo Kondoh, Manabu Morita

Experimental and therapeutic medicine 20 ( 3 ) 2822 - 2827 2020年9月

記述言語：英語掲載種別：研究論文（学術雑誌）出版者・発行元：Spandidos Publications

Salivary peroxidase and myeloperoxidase are known to display antibacterial activity against oral microbes, and previous indications have pointed to the possibility that horseradish peroxidase (HRP) adsorbs onto the membrane of the major oral streptococci, Streptococcus mutans and Streptococcus sanguinis (S. sanguinis). However, the mechanism of interaction between HRP and the bacterial cell wall component is unclear. Dental plaques containing salivary glycoproteins and extracellular microbial products are visualized with 'dental plaque disclosing agent', and are controlled within dental therapy. However, current 'dental plaque disclosing agents' are difficult to evaluate with just dental plaques, since they stain and disclose not only dental plaques but also pellicle formed with salivary glycoproteins on a tooth surface. In this present study, we have demonstrated that HRP interacted with the cell wall component of the major gram-positive bacterial peptidoglycan, but not the major cell wall component of gram-negative bacteria lipopolysaccharide. Furthermore, we observed that the adsorbed HRP labeled with fluorescence was detected on the major oral gram-positive strains S. sanguinis and Streptococcus salivarius (S. salivarius), but not on a gram-negative strain, Escherichia coli (E. coli). Furthermore, we have demonstrated that the combination of HRP and chromogenic substrate clearly disclosed the dental plaques and the biofilm developed by S. sanguinis, S. salivarius and the major gram-postive bacteria Lactobacillus casei on tooth surfaces, and slightly disclosed the biofilm by E. coli. The combination of HRP and chromogenic substrate did not stain either the dental pellicle with the salivary glycoprotein mucin, or naked tooth surfaces. These results have suggested the possibility that the adsorption activity of HRP not only contributes to the evaluation of dental plaque, but that enzymatic activity of HRP may also contribute to improve dental hygiene.

DOI： 10.3892/etm.2020.9016

PubMed

researchmap

　前のページ - 次のページ　

<江國 大輔>

論文 - 江國 大輔

<江國　大輔>

論文 - 江國　大輔