Updated on 2025/06/25

写真a

 
KAITO Chikara
 
Organization
Faculty of Medicine, Dentistry and Pharmaceutical Sciences Professor
Position
Professor
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Degree

  • Ph.D. ( The University of Tokyo )

Research Interests

  • 感染

  • モデル動物

  • 自然免疫

  • 毒素

  • 黄色ブドウ球菌

  • 病原性

  • カイコ

  • 感染症

  • 細菌学

  • 微生物学

  • 運動

  • RNA

  • 免疫

  • mobile genetic element

  • 薬剤耐性

  • 昆虫

  • 病原性微生物

  • Staphylococcus aureus

  • Colony Spreading

  • Silkworm model

Research Areas

  • Life Science / Bacteriology

Education

  • The University of Tokyo   大学院薬学系研究科   機能薬学専攻

    2000.4 - 2005.3

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    Country: Japan

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  • The University of Tokyo   理科二類/理学部   生物学科 動物学専攻

    1996.4 - 2000.3

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    Country: Japan

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  • 三重県立津高等学校    

    1992.4 - 1995.3

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Research History

  • Okayama University   Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences   Professor

    2019.1

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  • The University of Tokyo   Graduate School of Pharmaceutical Sciences   Associate Professor

    2010.7 - 2018.12

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  • The University of Tokyo   Graduate School of Pharmaceutical Sciences   Lecturer

    2008.3 - 2010.6

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  • The University of Tokyo   Graduate School of Pharmaceutical Sciences   Assistant Professor

    2007.4 - 2008.2

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  • The University of Tokyo   Graduate School of Pharmaceutical Sciences   Assistant Professor

    2005.7 - 2007.3

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  • 東京大学 大学院薬学系研究科 産学官連携研究員

    2005.4 - 2005.6

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Professional Memberships

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Committee Memberships

  • Microbiology and Immunology   Editors in Chief  

    2024.1   

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    Committee type:Academic society

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  • 日本細菌学会   理事  

    2021.1   

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    Committee type:Academic society

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  • Microbiology and Immunology   Deputy Editors-in-Chief  

    2021.1 - 2023.12   

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    Committee type:Academic society

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  • 日本医療研究開発機構   AMED委員  

    2017.4   

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    Committee type:Government

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  • 日本学術振興会   科学研究費 審査委員  

    2017   

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    Committee type:Government

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  • 日本ブドウ球菌研究会   運営委員  

    2016.6   

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    Committee type:Academic society

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  • PLOS ONE   Editorial Board  

    2016.6   

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    Committee type:Academic society

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Papers

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Books

  • 樹状細胞のMHC-IIを介した抗原提示の役割とその制御機構

    古田和幸, 垣内力( Role: Joint author)

    科学評論社:臨床免疫・アレルギー科 83(6):602-609  2025.6 

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  • 腸内細菌の代謝産物が樹状細胞を介した免疫応答に与える影響 〜短鎖脂肪酸による樹状突起伸長作用〜

    古田 和幸, 垣内 力( Role: Joint author)

    ファルマシア 60(7): 685-689・日本薬学会  2024.7 

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  • エンドソームと抗原提示

    古田 和幸、垣内 力( Role: Joint author)

    臨床免疫・アレルギー科 Vol.76 No.6 p622-628・科学評論社  2021.12 

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  • 進化実験による細菌病原性の理解

    垣内 力( Role: Sole author)

    羊土社・実験医学 増刊 39(2) p81-85「パンデミック時代の感染症研究 : 病原体の病原性、多様性、生活環から新型コロナウイルスを取り巻く社会の動きまで(編集:嘉糠洋陸)」  2021.2  ( ISBN:9784758103923

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    Total pages:209p   Language:Japanese

    CiNii Books

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  • 非ほ乳動物を用いた感染モデル

    Chikara Kaito( Role: Sole author)

    2017 

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  • 細菌間で保存された機能未知因子群からの新規病原性因子の同定

    Chikara Kaito( Role: Sole author)

    化学療法の領域 32(5):126-131. 医薬ジャーナル社  2016 

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  • 黄色ブドウ球菌の病原性制御機構に関する研究

    Chikara Kaito( Role: Sole author)

    日本細菌学雑誌 69(3):491-501. 日本細菌学会  2014 

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  • やさしい微生物学

    上原至雄, 垣内力, 北潔, 鈴木啓太郎, 関水和久, 辻勉, 細野哲司, 前田拓也, 牧純(編著者, 関水和久

    廣川書店  2011.4  ( ISBN:4567522109

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    Total pages:135  

    ASIN

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  • メチシリン耐性黄色ブドウ球菌のコロニースプレッディングおよび病原性発現調節を担う新規遺伝子「fudoh」

    Chikara Kaito

    感染・炎症・免疫 39(3):71-75. 医学の門社  2009 

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  • MRSAに見出された新規遺伝子「不動」

    Chikara Kaito

    化学療法の領域 25(8):46-53. 医薬ジャーナル社  2009 

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Industrial property rights

  • 病原性細菌の病原性を評価する方法、病原性の評価用キット及び病原性評価用遺伝子

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    Application no:特願2009-052647  Date applied:2009.2.17

    Announcement no:特開WO2009-154016 

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  • 感染症の予防又は治療のための薬剤及びその製造方法、評価方法及びスクリーニング方法、並びに、病原性細菌の病原異性の評価方法及び感染症の検査方法

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    Application no:特願2006-342713  Date applied:2006.12.20

    Announcement no:特開特開2008-148669 

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Awards

  • 小林六造記念賞

    2014.3   日本細菌学会  

    垣内 力

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Research Projects

  • 細菌の潜在的病原性をつかさどる分子基盤の解明

    Grant number:22H02869  2022 - 2024

    日本学術振興会  基盤研究(B) 

    垣内 力, 医歯薬学域

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    Authorship:Principal investigator 

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  • In vivo進化実験により病原性細菌出現の分子基盤に迫る

    Grant number:22K19435  2022 - 2023

    日本学術振興会 挑戦的研究(萌芽) 

    垣内 力, 医歯薬学域

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    Authorship:Principal investigator 

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  • 多様なRNA相互作用因子を介したグラム陽性細菌の病原性制御機構の解明

    2019 - 2021

    日本学術振興会  基盤研究(B) 

    垣内 力, 医歯薬学系

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    Authorship:Principal investigator  Grant type:Competitive

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  • in vivo実験的進化系を利用した細菌の病原性システムの解明

    2019 - 2020

    日本学術振興会  挑戦的研究(萌芽) 

    垣内 力, 医歯薬学系

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    Authorship:Principal investigator  Grant type:Competitive

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  • グラム陽性細菌の病原性発現に必要なRNA相互作用分子群の探索とその分子機能の解明

    2019

    公益財団法人 武田科学振興財団  2019年度薬学系研究助成 

    垣内 力, 医歯薬学系

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    Authorship:Principal investigator 

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  • 熱帯性コオロギ感染モデルを用いた細菌の温度依存性病原性発動メカニズムの解明

    2016 - 2017

    日本学術振興会  Grant-in-Aid for Challenging Exploratory Research 

    Chikara Kaito

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    Authorship:Principal investigator  Grant type:Competitive

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  • 治療効果を指向した新規抗菌薬の創出

    2015 - 2019

    日本学術振興会  基盤研究(S) 

    帝京大学, 関水 和久, 医真菌研究センター

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    Authorship:Coinvestigator(s)  Grant type:Competitive

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  • 世界の流行MRSAにおけるpsm-mec変異多型と病原性との関連性把握

    2015 - 2018

    日本学術振興会  Grant-in-Aid for Scientific Research (B)  基盤研究(B)

    垣内 力, 薬学系

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4290000 ( Direct expense: \3300000 、 Indirect expense:\990000 )

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  • 新規RNA結合タンパク質群による細菌の病原性発現機構の解明

    2015 - 2017

    日本学術振興会  Grant-in-Aid for Scientific Research (B)  基盤研究(B)

    垣内 力, 薬学系

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\6500000 ( Direct expense: \5000000 、 Indirect expense:\1500000 )

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  • 食用キノコに常在する微生物の生理的機能に関する研究

    2015

    薬学振興会(公財)  基礎的研究助成 

    Chikara Kaito

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    Authorship:Principal investigator  Grant type:Competitive

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  • 遺伝子組み換え常在細菌を利用した動物に対する成長ホルモン供給法の確立

    2014 - 2015

    日本学術振興会  Grant-in-Aid for Challenging Exploratory Research  挑戦的萌芽研究

    垣内 力, 薬学系

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3640000 ( Direct expense: \2800000 、 Indirect expense:\840000 )

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  • 新規RNA 結合蛋白質群による細菌の病原性調節機構の理解

    2014

    かなえ医薬振興財団  研究助成金 

    Chikara Kaito

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    Authorship:Principal investigator  Grant type:Competitive

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  • 黄色ブドウ球菌の細胞外毒素分泌トランスポーターの同定

    2014

    野田産業科学研究所(公財)  野田産研研究助成 奨励研究助成 

    Chikara Kaito

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    Authorship:Principal investigator  Grant type:Competitive

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  • 黄色ブドウ球菌の新規移動様式の分子機構

    2013 - 2014

    日本学術振興会  新学術領域研究(研究領域提案型)  新学術領域研究(研究領域提案型)

    垣内 力, 薬学系

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\10270000 ( Direct expense: \7900000 、 Indirect expense:\2370000 )

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  • 大腸菌の高病原性化をひきおこす分子機構の解明

    2013

    薬学研究奨励財団  研究助成金 グループA 

    Chikara Kaito

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    Authorship:Principal investigator  Grant type:Competitive

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  • 細菌の潜在的病原性を規定する分子機構の解明

    2013

    持田記念医学薬学振興財団  研究助成金 

    Chikara Kaito

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    Authorship:Principal investigator  Grant type:Competitive

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  • 外来遺伝子によるMRSAの病原性調節機構に関する研究

    2012 - 2014

    日本学術振興会  基盤研究(C)  基盤研究(C)

    垣内力, 薬学系

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\5460000 ( Direct expense: \4200000 、 Indirect expense:\1260000 )

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  • カイコ感染モデルを利用した宿主—病原体相互作用の理解

    2011 - 2013

    日本学術振興会  基盤研究(A) 

    関水 和久, 薬学系, 教授

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    Grant type:Competitive

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  • FudohによるMRSAの病原性制御

    2009

    内藤記念科学振興財団  内藤記念科学奨励金 

    垣内 力

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3000000

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  • カイコ感染モデルを基盤とした細菌の病原性発現システムの解明

    2008 - 2010

    日本学術振興会  基盤研究(B) 

    関水 和久, 薬学系, 教授

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    Grant type:Competitive

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  • Research on virulence regulatory mechanisms by CVF

    Grant number:20790057  2008 - 2009

    Ministry of Education, Culture, Sports, Science and Technology  Grants-in-Aid for Scientific Research(若手研究(B))  若手研究(B)

    Chikara KAITO

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\4290000 ( Direct expense: \3300000 、 Indirect expense:\990000 )

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  • カイコ感染モデルを用いたグラム陽性細菌に保存された病原性発現機構の解明

    2007 - 2008

    日本学術振興会  特定領域研究 

    関水 和久, 薬学系, 教授

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    Grant type:Competitive

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  • 黄色ブドウ球菌の滑走能低下を指標とした抗菌治療薬に関する研究

    2007

    日本学術振興会  萌芽研究 

    関水 和久, 薬学系, 教授

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    Grant type:Competitive

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  • 細胞間で保存された新規病原性遺伝子の同定

    2006 - 2007

    日本学術振興会  若手研究(B)  若手研究(B)

    垣内 力, 薬学系, 助手

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    Authorship:Principal investigator  Grant type:Competitive

    Grant amount:\3500000 ( Direct expense: \3500000 )

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  • 黄色ブドウ球菌の滑走能を規定する遺伝子群の探索

    2006

    薬学振興会(公財)  基礎的研究助成 

    Chikara Kaito

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    Authorship:Principal investigator  Grant type:Competitive

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  • カイコ感染モデルを用いた新規病原性遺伝子の同定

    2006

    JST  シーズ発掘試験研究 

    Chikara Kaito

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    Authorship:Principal investigator  Grant type:Competitive

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  • 黄色ブドウ球菌の宿主相互作用因子のカイコ感染モデルを用いた網羅的同定と機能解析

    2002 - 2004

    日本学術振興会  特別研究員奨励費(DC1) 

    垣内 力

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    Grant type:Competitive

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Class subject in charge

  • Advanced Lectures: Molecular Biology (2024academic year) special  - その他

  • Molecular Cell Biology 1 (2024academic year) 1st semester  - 月5~6

  • Molecular Cell Biology 1 (2024academic year) 1st semester  - 月5~6

  • Molecular Cell Biology 2 (2024academic year) Second semester  - 月5~6

  • Molecular Cell Biology 2 (2024academic year) Second semester  - 月5~6

  • Molecular Cell Biology 4 (2024academic year) Fourth semester  - 月5~6

  • Molecular Cell Biology 4 (2024academic year) Fourth semester  - 月5~6

  • Molecular Cell Biology A (2024academic year) 1st and 2nd semester  - 月5~6

  • Molecular Cell Biology A (2024academic year) 1st and 2nd semester  - 月5~6

  • Molecular Cell Biology C (2024academic year) Fourth semester  - 月5~6

  • Molecular Cell Biology C (2024academic year) Fourth semester  - 月5~6

  • Advanced Seminars in Drug Discovery and Drug Development (Regulation of Biological Reponses) (2024academic year) special  - その他

  • Life science for drug discovery (2024academic year) Third semester  - 木5~6

  • Basic Mathematical and Data Sciences (2024academic year) Third semester  - 月5~6

  • International Collaborative Pharmaceutical Education(Field Studies Overseas) (2024academic year) special  - その他

  • International Collaborative Pharmaceutical Education(Field Studies Overseas) (2024academic year) special  - その他

  • International Collaborative Pharmaceutical Education(Field Studies Overseas) (2024academic year) special  - その他

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  • Advanced Pharmaceutical Research (2023academic year) Summer concentration  - その他

  • Advanced Lectures: Molecular Biology (2023academic year) special  - その他

  • Molecular Cell Biology 1 (2023academic year) 1st semester  - 月5~6

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  • Molecular Cell Biology 2 (2023academic year) Second semester  - 月5~6

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  • Advanced Seminars in Drug Discovery and Drug Development (Regulation of Biological Reponses) (2023academic year) special  - その他

  • Life science for drug discovery (2023academic year) Third semester  - 木5~6

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  • Regulation of Biological Reponses (2023academic year) special  - その他

  • Regulation of Biological Reponses (2023academic year) special  - その他

  • Seminar on Regulation of Biological Reponses (2023academic year) special  - その他

  • Regulation of Biological Responses I (2023academic year) special  - その他

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  • Biological Chemistry 2 (2023academic year) Third semester  - 金3~4

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  • Practice in Hygienic Pharmaceutical Sciences (2023academic year) 2nd and 3rd semester  - その他5~9

  • Practice in Hygienic Pharmaceutical Sciences (2023academic year) 2nd and 3rd semester  - その他5~9

  • Practice in Hygienic Pharmaceutical Sciences (2023academic year) 2nd and 3rd semester  - その他5~9

  • Practice in Hygienic Pharmaceutical Sciences (2023academic year) 2nd and 3rd semester  - その他5~9

  • Advanced Pharmaceutical Research (2022academic year) Summer concentration  - その他

  • Molecular Cell Biology 1 (2022academic year) 1st semester  - 月5~6

  • Molecular Cell Biology 1 (2022academic year) 1st semester  - 月5~6

  • Molecular Cell Biology 2 (2022academic year) Second semester  - 月5~6

  • Molecular Cell Biology 2 (2022academic year) Second semester  - 月5~6

  • Molecular Cell Biology A (2022academic year) 1st and 2nd semester  - 月5~6

  • Molecular Cell Biology A (2022academic year) 1st and 2nd semester  - 月5~6

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  • Basic biology (2022academic year) 1st semester  - 水1~3

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  • Basic Biology (2022academic year) 1st semester  - 水1~3

  • Basic biology (2022academic year) 1st semester  - 水1~3

  • Regulation of Biological Reponses (2022academic year) special  - その他

  • Seminar on Regulation of Biological Reponses (2022academic year) special  - その他

  • Regulation of Biological Responses I (2022academic year) special  - その他

  • Regulation of Biological Responses II (2022academic year) special  - その他

  • Life Science 1 (2022academic year) special  - その他

  • Biological Chemistry 2 (2022academic year) Third semester  - 金3~4

  • Biological Chemistry 2 (2022academic year) Third semester  - 金3~4

  • Biological Chemistry B (2022academic year) Third semester  - 金3~4

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