研究者詳細 - 田邊　俊介

論文 - 田邊　俊介

分割表示 349 件中 161 - 180 件目／全件表示 >>

食道癌に対するウイルス治療、ワクチン治療の最前線食道癌に対する腫瘍融解ウイルス併用放射線療法の臨床研究の成果と展望

田辺俊介, 野間和広, 橋本将志, 最所公平, 賀島肇, 前田直見, 菊地覚次, 田澤大, 白川靖博, 藤原俊義

日本食道学会学術集会プログラム・抄録集 76回 59 - 59 2022年9月

食道癌手術における腹腔鏡下腹部郭清の定型化とその有用性

菊地覚次, 野間和広, 田辺俊介, 前田直見, 橋本将志, 最所公平, 賀島肇, 白川靖博, 藤原俊義

日本食道学会学術集会プログラム・抄録集 76回 108 - 108 2022年9月

胃管作製法と吻合法に着目した当科における食道切除後再建の変遷と工夫

國友知義, 野間和広, 橋本将志, 最所公平, 賀島肇, 前田直見, 菊池覚次, 田辺俊介, 白川靖博, 藤原俊義

日本食道学会学術集会プログラム・抄録集 76回 100 - 100 2022年9月

当院における高齢者進行食道癌に対する治療戦略

竹田泰茂, 野間和広, 橋本将志, 最所公平, 賀島肇, 前田直見, 菊地覚次, 田辺俊介, 白川靖博, 藤原俊義

日本食道学会学術集会プログラム・抄録集 76回 300 - 300 2022年9月

食道癌に対するサルベージロボット支援下胸腔鏡下食道亜全摘術5症例の検討

門脇大輔, 野間和広, 橋本将志, 最所公平, 賀島肇, 前田直見, 菊地覚次, 田辺俊介, 白川靖博, 藤原俊義

日本食道学会学術集会プログラム・抄録集 76回 186 - 186 2022年9月

食道癌・接合部癌における免疫チェックポイント阻害剤の意義と課題術前DCF療法を施行した食道根治術術後再発に対するNivolumabの有効性

橋本将志, 野間和広, 最所公平, 賀島肇, 前田直見, 菊地覚次, 田辺俊介, 白川靖博, 藤原俊義

日本食道学会学術集会プログラム・抄録集 76回 7 - 7 2022年9月

【ここまで進んだERAS】ERASにおけるチーム医療

野間和広, 田邊俊介, 藤原俊義

消化器外科 45 ( 9 ) 961 - 966 2022年9月

食道癌に対するウイルス治療、ワクチン治療の最前線抗腫瘍免疫賦活を介した腫瘍融解アデノウイルス製剤による免疫チェックポイント阻害薬治療増強効果の検討

橋本将志, 黒田新士, 金谷信彦, 田辺俊介, 前田直見, 野間和広, 田澤大, 白川靖博, 浦田泰生, 藤原俊義

日本食道学会学術集会プログラム・抄録集 76回 59 - 59 2022年9月

食道癌に対するウイルス治療、ワクチン治療の最前線食道癌に対する腫瘍融解ウイルス併用放射線療法の臨床研究の成果と展望

田辺俊介, 野間和広, 橋本将志, 最所公平, 賀島肇, 前田直見, 菊地覚次, 田澤大, 白川靖博, 藤原俊義

日本食道学会学術集会プログラム・抄録集 76回 59 - 59 2022年9月

Effectiveness of early exercise on reducing skeletal muscle loss during preoperative neoadjuvant chemotherapy for esophageal cancer. 査読

Tomohiro Ikeda, Kazuhiro Noma, Naoaki Maeda, Shunsuke Tanabe, Yoko Sakamoto, Yoshimi Katayama, Yasuhiro Shirakawa, Toshiyoshi Fujiwara, Masuo Senda

Surgery today 52 ( 8 ) 1143 - 1152 2022年8月

記述言語：英語掲載種別：研究論文（学術雑誌）

PURPOSE: To investigate if early exercise can help prevent skeletal muscle loss and improve the clinical outcomes of esophageal cancer patients receiving preoperative neoadjuvant chemotherapy (NAC). METHODS: This was a single-center, retrospective observational cohort study of 110 patients with advanced esophageal cancer. We analyzed the effect of early exercise on the risk of skeletal muscle loss (defined as > 2.98%) during NAC and the subsequent clinical outcomes. Patients in the early exercise group (n = 71) started exercise therapy 8 days earlier than those the late exercise group (n = 39). RESULTS: The median age of the patients was 65.4 years, the mean BMI was 21.1 kg/m2, and 92 (84%) of the 110 patients were men. Skeletal muscle loss occurred in 34% and 67% of the early and late exercise groups, respectively (p < 0.001). There was a lower risk of surgical site infection in the early exercise group (1% vs 16%, p = 0.021). Multivariate analysis revealed that early exercise reduced the risk of skeletal muscle loss (OR = 0.25, 95% CI 0.09-0.65, p = 0.006). CONCLUSIONS: Our results suggest that early exercise reduces the risk of both skeletal muscle loss during NAC and subsequent surgical site infection in patients with esophageal cancer.

DOI： 10.1007/s00595-021-02449-5

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Verrucous carcinoma of the esophagus with complete response after chemoradiotherapy. 査読国際誌

Masashi Hashimoto, Yasuhiro Shirakawa, Shunsuke Tanabe, Takehiro Tanaka, Naoaki Maeda, Kazufumi Sakurama, Kazuhiro Noma, Toshiyoshi Fujiwara

Surgical case reports 8 ( 1 ) 128 - 128 2022年7月

記述言語：英語掲載種別：研究論文（学術雑誌）

BACKGROUND: Verrucous carcinoma of the esophagus (VCE) is a rare tumor that is difficult to diagnose. In most cases, biopsies show nonspecific inflammatory and hyperkeratotic changes and do not show malignant findings. Most VCEs are slowly growing, locally advanced tumors with few metastases. Treatments for VCE are the same as for normal esophageal cancer, involving combined chemotherapy, surgical resection, and radiation therapy. However, it has been reported that VCE has a poor response to radiation or chemoradiotherapy (CRT). A case of VCE with complete response (CR) after CRT is presented. CASE PRESENTATION: A 70-year-old man was found to have white, irregular esophageal mucosa 4 years earlier. He had been followed up as an outpatient as having candidal esophagitis. However, his tumor grew gradually, and biopsy was performed by endoscopic mucosal resection (EMR). He was finally diagnosed with VCE. He had no metastases to distant organs, but some lymph node metastases were suspected. The tumor invaded his left bronchus. The esophagostomy and gastrostomy were constructed as emergent procedures. The patient then underwent definitive CRT. 4 weeks after the end of CRT, two-stage esophagectomy was performed. First, he underwent esophagectomy with thoracic lymph node dissection. A latissimus dorsi flap was patched to the bronchus after primary suture of the hole. 6 weeks later, reconstruction of the gastric tube was performed through the antethoracic route. The pathological findings showed CR to CRT, with no proliferative cancer cells in the specimen. The patient has had no recurrence for three and half years after the resection. CONCLUSIONS: We presented a locally advanced VCE that achieved CR to CRT. In cases that have some difficulty for local resection, CRT might be an appropriate treatment for VCE.

DOI： 10.1186/s40792-022-01486-7

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狭窄を伴う食道癌患者における術前胃瘻造設と周術期管理チームの有用性

橋本将志, 野間和広, 前田直見, 菊地覚次, 田辺俊介, 黒田新士, 寺石文則, 楳田祐三, 白川靖博, 藤原俊義

日本消化器外科学会総会 77回 P147 - 3 2022年7月

継続的な栄養指導と術後早期アミノ酸投与による胃切除術後の体重・筋肉量減少抑制効果

菊地覚次, 高田暢夫, 黒田新士, 垣内慶彦, 田辺俊介, 前田直見, 野間和広, 楳田祐三, 香川俊輔, 藤原俊義

日本消化器外科学会総会 77回 O4 - 3 2022年7月

高度局所進行食道癌に対する術前DCF療法plusロボット支援下手術

野間和広, 西脇紀之, 前田直見, 菊地覚次, 田辺俊介, 黒田新士, 寺石文則, 楳田祐三, 白川靖博, 藤原俊義

日本消化器外科学会総会 77回 O1 - 5 2022年7月

Impact of Amino Acids Nutrition Following Gastrectomy in Gastric Cancer Patients. 査読国際誌

Satoru Kikuchi, Nobuo Takata, Shinji Kuroda, Hibiki Umeda, Shunsuke Tanabe, Naoaki Maeda, Kosei Takagi, Kazuhiro Noma, Yuko Hasegawa, Kumiko Nawachi, Shunsuke Kagawa, Yuzo Umeda, Kenichi Shikata, Toshiyoshi Fujiwara

Anticancer research 42 ( 7 ) 3637 - 3643 2022年7月

記述言語：英語掲載種別：研究論文（学術雑誌）

BACKGROUND/AIM: Postoperative body weight loss (BWL) and skeletal muscle loss (SML) after gastrectomy are associated with a decline in quality of life and worse longterm prognosis in gastric cancer (GC) patients. This study aimed to evaluate the efficacy of amino acids nutrition on BWL and SML in the early period following gastrectomy. PATIENTS AND METHODS: The parameters of body composition were measured by bioelectrical impedance analysis in the patients undergoing radical gastrectomy for GC and analyzed retrospectively. Patients received either peripheral parenteral nutrition (PPN) of 4.3% glucose fluid with regular diet (control group, n=43) or PPN of 7.5% glucose fluid containing amino acids plus oral nutritional supplement (ONS) rich in protein with regular diet (amino acids group, n=40) following gastrectomy. The percentages of BWL and SML from preoperative values to those at 7 days and 1 month after surgery were compared between the two groups. RESULTS: The %BWL and %SML at 7 days after surgery were significantly lower in the amino acids group than those in the control group (%BWL, -2.4±1.7% vs. -4.2±1.8%; p<0.0001, %SML, -4.1±3.8 vs. -6.5±3.8; p=0.006). Moreover, the %BWL at 1 month after surgery was significantly lower in the amino acids group compared to that in the control group (- 4.6±2.9% vs. -6.1±2.6%; p=0.01); however, the %SML was similar between the two groups. The hematological nutritional parameters were similar between the two groups. CONCLUSION: Amino acids nutrition by PPN and ONS following gastrectomy prevented postoperative BWL and SML in the early period after surgery in GC patients.

DOI： 10.21873/anticanres.15852

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【総論】各臓器サブサブスペシャルティ外科医の育成法食道外科におけるサブサブスペシャリティ取得への取組み

前田直見, 野間和広, 菊地覚次, 田辺俊介, 黒田新士, 吉田龍一, 寺石文則, 楳田祐三, 白川靖博, 藤原俊義

日本消化器外科学会総会 77回 WS15 - 9 2022年7月