2021/04/08 更新

写真a

ゴウバラ ヒデオ
郷原 英夫
GOBARA Hideo
所属
岡山大学病院 教授
職名
教授
外部リンク

学位

  • 医学博士 ( 岡山大学 )

研究キーワード

  • interventional radiology

  • radiofrequency ablation

  • 画像診断

  • IVR

  • ラジオ波焼灼

  • diagnositic radiology

  • 医療情報学

研究分野

  • 情報通信 / 生命、健康、医療情報学

  • ライフサイエンス / 放射線科学

学歴

  • 岡山大学   Graduate School, Division of Medicine  

    - 1994年

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  • 岡山大学    

    - 1994年

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    国名: 日本国

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経歴

  • - 岡山大学岡山大学病院 教授

    2016年

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  • - Professor,University Hospital of Medicine and Dentistry,Okayama University

    2016年

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  • Associate Professor,University Hospital of Medicine and Dentistry,Okayama University

    2014年 - 2016年

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  • 岡山大学岡山大学病院 准教授   Okayama University Hospital

    2014年 - 2016年

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  • 岡山大学岡山大学病院 講師   Okayama University Hospital

    2011年 - 2014年

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  • Senior Assistant Professor,University Hospital of Medicine and Dentistry,Okayama University

    2011年 - 2014年

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  • Assistant Professor,University Hospital of Medicine and Dentistry,Okayama University

    2004年 - 2011年

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  • 岡山大学岡山大学病院 助教   Okayama University Hospital

    2004年 - 2011年

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▼全件表示

 

書籍等出版物

  • 先端医療NAVIGATORⅡ

    日本医学出版  2014年 

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  • 先端医療NAVIGATORⅡ

    日本医学出版  2014年 

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  • Colorectal Cancer:Risk, Diagnosis and Treatments.

    Nova Science Publishers  2011年 

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  • 平成17年度 科学研究費補助金(基盤研究(C))実績報告書

    2005年 

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  • 画像診断を考える -よりよい診断のために-

    秀潤社  2003年 

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MISC

  • CT fluoroscopy-guided core needle biopsy of anterior mediastinal masses

    T. Iguchi, T. Hiraki, Y. Matsui, H. Fujiwara, J. Sakurai, Y. Masaoka, M. Uka, T. Tanaka, H. Gobara, S. Kanazawa

    Diagnostic and Interventional Imaging99 ( 2 ) 91 - 97   2018年2月

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    記述言語:英語   出版者・発行元:Elsevier Masson SAS  

    Objective: To retrospectively evaluate the safety, diagnostic yield, and risk factors of diagnostic failure of computed tomography (CT) fluoroscopy-guided biopsies of anterior mediastinal masses. Materials and methods: Biopsy procedures and results of anterior mediastinal masses in 71 patients (32 women/39 men
    mean [± standard deviation] age, 53.8 ± 20.0 years
    range, 14–88 years) were analyzed. Final diagnoses were based on surgical outcomes, imaging findings, or clinical follow-up findings. The biopsy results were compared with the final diagnosis, and the biopsy procedures grouped by pathologic findings into diagnostic success and failure groups. Multiple putative risk factors for diagnostic failure were then assessed. Results: Seventy-one biopsies (71 masses
    mean size, 67.5 ± 27.3 mm
    range 8.6–128.2 mm) were analyzed. We identified 17 grade 1 and one grade 2 adverse events (25.4% overall) according to the National Cancer Institute Common Terminology Criteria for Adverse Events version 4.0. Sixty-nine biopsies (97.2%) provided samples fit for pathologic analysis. Diagnostic failure was found for eight (11.3%) masses
    the 63 masses diagnosed successfully included thymic carcinoma (n = 17), lung cancer (n = 14), thymoma (n = 12), malignant lymphoma (n = 11), germ cell tumor (n = 3), and others (n = 6). Using a thinner needle (i.e., a 20-gauge needle) was the sole significant risk factor for diagnostic failure (P = 0.039). Conclusion: CT fluoroscopy-guided biopsy of anterior mediastinal masses was safe and had a high diagnostic yield
    however, using a thinner biopsy needle significantly increased the risk of a failed diagnosis.

    DOI: 10.1016/j.diii.2017.10.007

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  • Robotically Driven CT-guided Needle Insertion: Preliminary Results in Phantom and Animal Experiments

    Takao Hiraki, Tetsushi Kamegawa, Takayuki Matsuno, Jun Sakurai, Yasuzo Kirita, Ryutaro Matsuura, Takuya Yamaguchi, Takanori Sasaki, Toshiharu Mitsuhashi, Toshiyuki Komaki, Yoshihisa Masaoka, Yusuke Matsui, Hiroyasu Fujiwara, Toshihiro Iguchi, Hideo Gobara, Susumu Kanazawa

    RADIOLOGY285 ( 2 ) 454 - 461   2017年11月

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    記述言語:英語   出版者・発行元:RADIOLOGICAL SOC NORTH AMERICA  

    Purpose: To evaluate the accuracy of the remote-controlled robotic computed tomography (CT)-guided needle insertion in phantom and animal experiments.
    Materials and Methods: In a phantom experiment, 18 robotic and manual insertions each were performed with 19-gauge needles by using CT fluoroscopic guidance for the evaluation of the equivalence of accuracy of insertion between the two groups with a 1.0-mm margin. Needle insertion time, CT fluoroscopy time, and radiation exposure were compared by using the Student t test. The animal experiments were approved by the institutional animal care and use committee. In the animal experiment, five robotic insertions each were attempted toward targets in the liver, kidneys, lungs, and hip muscle of three swine by using 19-gauge or 17-gauge needles and by using conventional CT guidance. The feasibility, safety, and accuracy of robotic insertion were evaluated.
    Results: The mean accuracies of robotic and manual insertion in phantoms were 1.6 and 1.4 mm, respectively. The 95% confidence interval of the mean difference was 20.3 to 0.6 mm. There were no significant differences in needle insertion time, CT fluoroscopy time, or radiation exposure to the phantom between the two methods. Effective dose to the physician during robotic insertion was always 0 mSv, while that during manual insertion was 5.7 mSv on average (P<.001). Robotic insertion was feasible in the animals, with an overall mean accuracy of 3.2 mm and three minor procedure-related complications.
    Conclusion: Robotic insertion exhibited equivalent accuracy as manual insertion in phantoms, without radiation exposure to the physician. It was also found to be accurate in an in vivo procedure in animals. (C) RSNA, 2017

    DOI: 10.1148/radiol.2017162856

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  • Robotically Driven CT-guided Needle Insertion: Preliminary Results in Phantom and Animal Experiments

    Takao Hiraki, Tetsushi Kamegawa, Takayuki Matsuno, Jun Sakurai, Yasuzo Kirita, Ryutaro Matsuura, Takuya Yamaguchi, Takanori Sasaki, Toshiharu Mitsuhashi, Toshiyuki Komaki, Yoshihisa Masaoka, Yusuke Matsui, Hiroyasu Fujiwara, Toshihiro Iguchi, Hideo Gobara, Susumu Kanazawa

    RADIOLOGY285 ( 2 ) 454 - 461   2017年11月

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    記述言語:英語   出版者・発行元:RADIOLOGICAL SOC NORTH AMERICA  

    Purpose: To evaluate the accuracy of the remote-controlled robotic computed tomography (CT)-guided needle insertion in phantom and animal experiments.
    Materials and Methods: In a phantom experiment, 18 robotic and manual insertions each were performed with 19-gauge needles by using CT fluoroscopic guidance for the evaluation of the equivalence of accuracy of insertion between the two groups with a 1.0-mm margin. Needle insertion time, CT fluoroscopy time, and radiation exposure were compared by using the Student t test. The animal experiments were approved by the institutional animal care and use committee. In the animal experiment, five robotic insertions each were attempted toward targets in the liver, kidneys, lungs, and hip muscle of three swine by using 19-gauge or 17-gauge needles and by using conventional CT guidance. The feasibility, safety, and accuracy of robotic insertion were evaluated.
    Results: The mean accuracies of robotic and manual insertion in phantoms were 1.6 and 1.4 mm, respectively. The 95% confidence interval of the mean difference was 20.3 to 0.6 mm. There were no significant differences in needle insertion time, CT fluoroscopy time, or radiation exposure to the phantom between the two methods. Effective dose to the physician during robotic insertion was always 0 mSv, while that during manual insertion was 5.7 mSv on average (P<.001). Robotic insertion was feasible in the animals, with an overall mean accuracy of 3.2 mm and three minor procedure-related complications.
    Conclusion: Robotic insertion exhibited equivalent accuracy as manual insertion in phantoms, without radiation exposure to the physician. It was also found to be accurate in an in vivo procedure in animals. (C) RSNA, 2017

    DOI: 10.1148/radiol.2017162856

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  • Radiofrequency ablation of pulmonary tumors near the diaphragm

    T. Iguchi, T. Hiraki, H. Gobara, H. Fujiwara, J. Sakurai, Y. Matsui, T. Mitsuhashi, S. Toyooka, S. Kanazawa

    DIAGNOSTIC AND INTERVENTIONAL IMAGING98 ( 7-8 ) 535 - 541   2017年7月

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    記述言語:英語   出版者・発行元:ELSEVIER MASSON  

    Purpose: To retrospectively evaluate the feasibility, safety, and efficacy of radiofrequency ablation (RFA) of lung tumors located near the diaphragm.
    Materials and methods: A total of 26 patients (15 men, 11 women; mean age, 61.5 years +/- 13.0 [SD]) with a total of 29 lung tumors near the diaphragm (i.e., distance < 10 mm) were included. Mean tumor diameter was 11.0 mm +/- 5.3 (SD) (range, 2-23 mm). Efficacy of RFA, number of adverse events and number of adverse events with a grade >= 3, based on the National Cancer Institute Common Terminology Criteria for Adverse Events, version 4.0, were compared between patients with lung tumors near the diaphragm and a control group of patients with more distally located lung tumors (i.e., distance >= 10 mm).
    Results: RFA was technically feasible for all tumors near the diaphragm. Four grade 3 adverse events (1 pneumothorax requiring pleurodesis and 3 phrenic nerve injuries) were observed. No grade >= 4 adverse events were reported. The median follow-up period for tumors near the diaphragm was 18.3 months. Local progression was observed 3.3 months after RFA in 1 tumor. The technique efficacy rates were 96.2% at 1 year and 96.2% at 2 years and were not different, from those observed in control subjects (186 tumors; P = 0.839). Shoulder pain (P < 0.001) and grade 1 pleural effusion (P < 0.001) were more frequently observed in patients with lung tumor near the diaphragm. The rates of grade >= 3 adverse events did not significantly differ between tumors near the diaphragm (4/26 sessions) and the controls (7/133 sessions) (P = 0.083).
    Conclusion: RFA is a feasible and effective therapeutic option for lung tumors located near the diaphragm. However, it conveys a higher rate of shoulder pain and asymptomatic pleural effusion by comparison with more distant lung tumors. (C) 2017 Editions francaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

    DOI: 10.1016/j.diii.2017.01.008

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  • Disappearance of Renal Cysts Included in Ice Ball During Cryoablation of Renal-Cell Carcinoma: A Potential Therapy for Symptomatic Renal Cysts?

    Mitsuko Yodoya, Takao Hiraki, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Yoshihisa Masaoka, Jun Sakurai, Toshiharu Mitsuhashi, Hideo Gobara, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY28 ( 6 ) 869 - 876   2017年6月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To retrospectively evaluate the effect of cryoablation of renal-cell carcinoma on nearby renal cysts with the goal to investigate the potential for an alternative therapy to treat symptomatic renal cysts.
    Materials and Methods: The study population comprised 46 cysts (mean size, 12 mm; range, 5-43 mm) that were within or near the ice ball during cryoablation in 22 patients. Size change of each cyst was evaluated via enhanced CT or MR imaging before and 1, 3, 6, and 12 months after cryoablation. Forty-one cysts were also followed after 12 months. Variables including positional relationship between the cyst and the ice ball were evaluated via linear regression analysis using generalized estimating equation models to determine which factors affected cyst shrinkage rate at 12 months.
    Results: Fifteen, 12, and 19 cysts were completely included in, partially included in, or excluded from the ice ball, respectively. The overall shrinkage rate was 62%, and 57% of cysts (26 of 46) had disappeared at 12 months. Only the relationship between the cyst and the ice ball was significantly (P < .001) associated with cyst shrinkage rate. Cyst disappearance rates at 12 months were 100% (15 of 15), 67% (8 of 12), and 16% (3 of 19) for cysts completely included, partially included, and excluded from the ice ball, respectively: Among the 22 cysts that disappeared at 12 months and continued to be followed, none recurred after 12 months.
    Conclusions: All renal cysts that were completely included in the ice ball disappeared after cryoablation, demonstrating the potential utility of cryoablation as an alternative therapy for symptomatic renal cysts.

    DOI: 10.1016/j.jvir.2017.02.027

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  • Radiofrequency ablation of pulmonary metastases from sarcoma: single-center retrospective evaluation of 46 patients

    Takuya Sato, Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Jun Sakurai, Yusuke Matsui, Toshiharu Mitsuhashi, Junichi Soh, Shinichi Toyooka, Susumu Kanazawa

    JAPANESE JOURNAL OF RADIOLOGY35 ( 2 ) 61 - 67   2017年2月

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    記述言語:英語   出版者・発行元:SPRINGER  

    This retrospective, single-center study evaluated radiofrequency (RF) ablation for pulmonary metastases of sarcoma.
    Forty-six patients with sarcoma (144 pulmonary metastases) underwent 88 RF ablation sessions. Data regarding local tumor progression, efficacy, procedural adverse events (AEs; National Cancer Institute Common Terminology Criteria for Adverse Events, version 4.0), overall survival (OS), and OS-associated prognostic factors were retrospectively evaluated using univariate analyses.
    Local progression occurred in 22 of 144 tumors (15.3%). Primary and secondary efficacy rates were 83.5 and 90.0% at 1 year and 76.3 and 81.4% at 2 years, respectively. Seventy-three grade 1 AEs, 33 grade 2 AEs, and no grade >= 3 AEs were observed. Twenty-eight patients (60.9%) remained alive and 18 died, yielding 1-, 2-, and 3-year OS rates of 80.6, 70.1, and 47.1% (median survival time, 31.7 months). Univariate analysis revealed extrapulmonary metastasis (P = 0.005), noncurative RF ablation (P = 0.009), and a post-RF ablation disease-free interval of <= 12 months (P = 0.015) as significant negative prognostic factors.
    RF ablation is safe, offers good local control, and may be a viable treatment option for pulmonary metastasis of sarcoma.

    DOI: 10.1007/s11604-016-0601-z

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  • Radiofrequency ablation of pulmonary metastases from sarcoma: single-center retrospective evaluation of 46 patients

    Takuya Sato, Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Jun Sakurai, Yusuke Matsui, Toshiharu Mitsuhashi, Junichi Soh, Shinichi Toyooka, Susumu Kanazawa

    JAPANESE JOURNAL OF RADIOLOGY35 ( 2 ) 61 - 67   2017年2月

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    記述言語:英語   出版者・発行元:SPRINGER  

    This retrospective, single-center study evaluated radiofrequency (RF) ablation for pulmonary metastases of sarcoma.
    Forty-six patients with sarcoma (144 pulmonary metastases) underwent 88 RF ablation sessions. Data regarding local tumor progression, efficacy, procedural adverse events (AEs; National Cancer Institute Common Terminology Criteria for Adverse Events, version 4.0), overall survival (OS), and OS-associated prognostic factors were retrospectively evaluated using univariate analyses.
    Local progression occurred in 22 of 144 tumors (15.3%). Primary and secondary efficacy rates were 83.5 and 90.0% at 1 year and 76.3 and 81.4% at 2 years, respectively. Seventy-three grade 1 AEs, 33 grade 2 AEs, and no grade >= 3 AEs were observed. Twenty-eight patients (60.9%) remained alive and 18 died, yielding 1-, 2-, and 3-year OS rates of 80.6, 70.1, and 47.1% (median survival time, 31.7 months). Univariate analysis revealed extrapulmonary metastasis (P = 0.005), noncurative RF ablation (P = 0.009), and a post-RF ablation disease-free interval of <= 12 months (P = 0.015) as significant negative prognostic factors.
    RF ablation is safe, offers good local control, and may be a viable treatment option for pulmonary metastasis of sarcoma.

    DOI: 10.1007/s11604-016-0601-z

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  • Preoperative short hookwire placement for small pulmonary lesions

    Toshihiro Iguchi, Takao Hiraki, Yusuke Matsui, Hiroyasu Fujiwara, Yoshihisa Masaoka, Takashi Tanaka, Takuya Sato, Hideo Gobara, Shinichi Toyooka, Susumu Kanazawa

    European Radiology   1 - 9   2017年

  • A Case of Solitary Metastasis from a Hepatocellular Carcinoma to the Sacral Bone Successfully Treated with Percutaneous Cryoablation.

    Noriyuki Umakoshi, Hideo Gobara, Takao Hiraki, Toshihiro Iguchi, Hiroyasu Fujiwara, Jun Sakurai, Yusuke Matsui, Yoshihisa Masaoka, Hiroki Ihara, Toshiaki Wada, Tomonori Seno, Susumu Kanazawa

    Interventional Radiology2 ( 1 ) 14 - 18   2017年

  • CT fluoroscopy-guided renal tumour cutting needle biopsy

    Toshihiro Iguchi, Takao Hiraki, Yusuke Matsui, Hiroyasu Fujiwara, Jun Sakurai, Yoshihisa Masaoka, Hideo Gobara, Susumu Kanazawa

    European Radiology   1 - 8   2017年

  • Needle Tract Seeding after Percutaneous Cryoablation of a Metastatic Hepatic Tumor from Renal Cell Carcinoma: A Case Report

    Hideo Gobara, Toshiyuki Komaki, Toshihiro Iguchi, Hiroyasu Fujiwara, Jun Sakurai, Yusuke Matsui, Mayu Uka, Yoshihisa Masaoka, Yuzo Umeda, Takao Hiraki, Susumu Kanazawa

    Interventional Radiology2 ( 3 ) 104 - 107   2017年

  • 消化管用ステントを用いた下大静脈ステント留置術が有効であった悪性下大静脈症候群の1例.

    小牧稔幸, 郷原英夫, 平木隆夫, 藤原寛康, 生口俊浩, 櫻井 淳, 松井裕輔, 金澤 右

    臨床放射線62 ( 5 ) 725 - 728   2017年

  • Value of percutaneous needle biopsy of small renal tumors in patients referred for cryoablation

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Jun Sakurai, Yusuke Matsui, Motoo Araki, Yasutomo Nasu, Susumu Kanazawa

    MINIMALLY INVASIVE THERAPY & ALLIED TECHNOLOGIES26 ( 2 ) 86 - 91   2017年

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    記述言語:英語   出版者・発行元:TAYLOR & FRANCIS LTD  

    Purpose: To retrospectively evaluate the safety and diagnostic yield of needle biopsy of small renal tumors, and the clinical consequences of performing needle biopsy in patients referred for percutaneous cryoablation before their treatment.
    Material and methods: Biopsy was performed for 120 tumors (mean diameter, 2.2 cm) in 119 patients. All procedures were divided into diagnostic and non-diagnostic biopsies. Various variables were compared between the two groups. All cryoablation procedures were divided into two groups: procedures with or without simultaneous biopsy. The rates of benign or non-diagnostic tumors in each group were compared.
    Results: After performing 120 initial and eight repeat biopsies, Grade 1 bleedings occurred in 44 cases. Six tumors were non-diagnostic and 114 were pathologically diagnosed. There were no significant variables between the diagnostic and non-diagnostic biopsies. Unnecessary cryoablation was avoided in nine benign lesions by performing biopsy in advance. Cryoablation performed simultaneously with biopsy included significantly more benign or non-diagnostic tumors than cryoablation performed after biopsy (15.2% vs. 1.4%; p =.01).
    Conclusions: Percutaneous biopsy of small renal tumors referred for cryoablation was a safe procedure with high diagnostic yield. The confirmation of pathological diagnosis prior to cryoablation is necessary because patients with benign tumors can avoid unnecessary treatment.

    DOI: 10.1080/13645706.2016.1249889

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  • 腎凍結療法

    藤原寛康, 平木隆夫, 生口俊浩, 郷原英夫, 松井祐輔, 金澤 右

    日本IVR学会雑誌   2017年

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  • Fracture of totally implanted central venous access devices: a propensity-score-matched comparison of risks for Groshong silicone versus polyurethane catheters

    Soichi Kojima, Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Toshiharu Mitsuhashi, Susumu Kanazawa

    JOURNAL OF VASCULAR ACCESS17 ( 6 ) 535 - 541   2016年11月

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    記述言語:英語   出版者・発行元:WICHTIG PUBLISHING  

    Purpose: To evaluate retrospectively the fracture risk of totally implanted venous access devices connected to Groshong silicone (SC) versus polyurethane (PU) catheters, inserted via the internal jugular vein.
    Materials and methods: The study population comprised 384 SC and 221 PU central venous catheters implanted via the internal jugular vein. The presence of catheter fracture was evaluated. Variables possibly related to catheter fracture were evaluated. First, in order to determine the factors associated with fracture, fracture rates were compared with the log-rank test between the two groups divided by each of the variables. Then, in order to adjust for potential confounders, propensity-score matching of the variables was employed in the two catheter groups. Finally, the rates of fracture were compared between the two propensity-score-matched catheter groups.
    Results: There were 16 cases of catheter fracture, for an overall fracture percentage of 2.6% (16/605). All 16 cases of fracture occurred in the SC catheter group. Smaller patient body mass index (p = 0.039), deeper catheter tip position (p = 0.022), and SC catheters (p = 0.019) were significantly associated with fracture. With the propensity-score- matching method, 180 cases were selected in each catheter group. Comparison of the two propensity-score- matched groups showed that fracture rates for SC catheters remained significantly (p = 0.018) higher than those for PU catheters.
    Conclusions: Ports connected to Groshong SC catheters - when implanted via the internal jugular vein - posed a higher risk of fracture than did ports connected to PU catheters.

    DOI: 10.5301/jva.5000606

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  • Simultaneous biopsy and radiofrequency ablation of T1a renal cell carcinoma

    T. Iguchi, T. Hiraki, K. Tomita, H. Gobara, H. Fujiwara, J. Sakurai, Y. Matsui, S. Kanazawa

    DIAGNOSTIC AND INTERVENTIONAL IMAGING97 ( 11 ) 1159 - 1164   2016年11月

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    記述言語:英語   出版者・発行元:ELSEVIER MASSON  

    Objective: The goal of this study was to retrospectively evaluate the outcome, including feasibility, safety, diagnostic yield, and factors affecting the success of computed tomography fluoroscopy-guided biopsy when performed during the same procedure than radiofrequency ablation (RFA) in renal tumors strongly suspected of being T1a renal cell carcinoma (RCC).
    Materials and methods: Nineteen patients (13 men, 6 women; mean age, 66.7 years) with a total of 19 suspected renal tumors (mean diameter, 1.8 cm) underwent computed tomography fluoroscopy-guided biopsy during (n = 6) or immediately after (n = 13) RFA. All patients were strongly suspected of having RCC on the basis of patient's medical histories and/or the results of imaging investigations. All procedures were divided into diagnostic and non-diagnostic biopsies. Various variables were compared between the 2 groups using univariate analysis.
    Results: In all tumors, biopsy procedures were technically feasible. No major complications were observed, except for 8 minor post-procedural bleedings. All but one tumor was completely ablated. Local recurrence in the ablation zone as well as tumor seeding in retroperitoneal fat occurred in 1 patient 8.5 months after the procedure and were successfully treated with further percutaneous cryoablation. Thirteen tumors were diagnosed as RCC, whereas 6 were ultimately found to contain normal renal tissue (n = 5) or connective tissue (n = 1). Univariate analysis revealed that none of the variables were significantly different between the diagnostic and non-diagnostic biopsies.
    Conclusion: The performance of renal tumor biopsy and RFA in the same session is feasible and safe. Although pre-treatment pathological diagnosis would be generally desirable, simultaneous biopsy with RFA can be an option for the patients who are not amenable to pre-treatment biopsy. (C) 2016 Editions francaises de radiologie. Published by Elsevier Masson SAS. All rights reserved.

    DOI: 10.1016/j.diii.2016.05.001

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  • Phase I/II Multi-Institutional Study of Percutaneous Radiofrequency Ablation for Painful Osteoid Osteoma (JIVROSG-0704)

    Masaya Miyazaki, Yasuaki Arai, Akira Myoui, Hideo Gobara, Miyuki Sone, Daniel I. Rosenthal, Yoshito Tsushima, Susumu Kanazawa, Shigeru Ehara, Keigo Endo

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY39 ( 10 ) 1464 - 1470   2016年10月

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    記述言語:英語   出版者・発行元:SPRINGER  

    This multicenter prospective study was conducted to evaluate the safety and efficacy of percutaneous radiofrequency ablation (RFA) for painful osteoid osteoma (OO).
    Patients with OO (femur: n = 17, tibia: n = 2, humerus: n = 1, rib: n = 1) were enrolled and treated with RFA. In phase I, nine patients were evaluated for safety. In phase II, 12 patients were accrued, and an intent-to-treat analysis was performed on all patients. The primary endpoint was to evaluate the treatment safety. The secondary endpoint was to evaluate the efficacy for pain relief by the visual analogue scale (VAS) at 4 weeks after RFA. Treatment efficacy was classified as significantly effective (SE) when VAS score decreased by aeyen5 or score was < 2, moderately effective when VAS score decreased by < 5-aeyen2 and score was aeyen2, and not effective (NE) when VAS score decreased by < 2 or score was increased. Cases where the need for analgesics increased after treatment were also NE.
    RFA procedures were completed in all patients. Minor adverse effects (AEs) were observed as 4.8-14.3 % in 12 patients, and no major AEs were observed. Mean VAS score was 7.1 before treatment, 1.6 at 1 week, 0.3 at 4 weeks, and 0.2 at 3 months. All procedures were classified as SE. Pain recurrence was not noted in any patient during follow-up (mean: 15.1 months).
    RFA is a safe, highly effective, and fast-acting treatment for painful extraspinal OO. Future studies with a greater number of patients are needed.

    DOI: 10.1007/s00270-016-1438-7

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  • Long-Term Survival after Radiofrequency Ablation of Lung Oligometastases from Five Types of Primary Lesions: A Retrospective Evaluation

    Kenichi Omae, Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Shinichi Toyooka, Takeshi Nagasaka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY27 ( 9 ) 1362 - 1370   2016年9月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To conduct a retrospective evaluation of long-term survival after radiofrequency (RF) ablation for lung oligometastases from 5 types of primary lesions.
    Materials and Methods: The study population consisted of 123 patients with lung oligometastases from colorectal cancer (CRC), non small-cell lung cancer, hepatocellular carcinoma, esophageal cancer, and renal-cell carcinoma treated with RF ablation. Lung oligometastases were defined as 1-5 Metastases confined to the lung while the primary cancer and other metastases were eradicated. Overall survival (OS) and recurrence-free survival (RFS) were estimated for-the overall study population and for patients with each type of primary lesion. The OS and RFS rates were compared with those of the patients with any of the other four primary lesion types. Finally, various variables were analyzed to determine what factors influenced OS and RFS.
    Results: The Median follow-up was 45.7 months; and the 5-year-OS and RFS rates for all 123 patients Were 62% and 25%, respectively, The OS :time for patients with metastases from. CRC was significantly longer (P = .042); it was significantly shorter (P = .022) in patients with metastases from esophageal cancer. Longer disease-free interval was significantly (P = .015) associated with better OS. There was no variable significantly associated with OS and RFS on multivariate analyses.
    Conclusions: Data from this single-center study appear promising in terms of long-term survival after RF ablation of lung oligometastases from 5 primary lesions.

    DOI: 10.1016/j.jvir.2016.05.017

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  • Percutaneous radiofrequency ablation for patients with malignant lung tumors: a phase II prospective multicenter study (JIVROSG-0702)

    Hideo Gobara, Yasuaki Arai, Takeshi Kobayashi, Koichiro Yamakado, Yoshitaka Inaba, Yoshihisa Kodama, Takuji Yamagami, Miyuki Sone, Hirokazu Watanabe, Yoshihiro Okumura, Takayoshi Shinya, Hiroaki Kurihara, Susumu Kanazawa

    JAPANESE JOURNAL OF RADIOLOGY34 ( 8 ) 556 - 563   2016年8月

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    記述言語:英語   出版者・発行元:SPRINGER  

    This prospective multicenter study aimed to evaluate the efficacy and safety of percutaneous radiofrequency (RF) ablation for lung cancer.
    From May 2008 to April 2012, 33 patients (26 men, 7 women; mean age 70.5 years) were enrolled. RF ablation was performed using an internally cooled or expandable multitined electrode. The primary endpoint was complete response (CR) determined using F-18 fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) performed 6 months after RF ablation. The secondary endpoint was the incidence and grade of adverse events (AEs) evaluated using the Common Toxicity Criteria for Adverse Events, version 3.0.
    All patients underwent RF ablation and had efficacy analyses evaluated; however, FDG-PET/CT images before RF ablation were not available for two patients. The CR rate was 68 % (21 of 31 patients). One patient had a grade 5 AE unrelated to RF ablation. Grade a parts per thousand yen3 AEs occurred in 12 % of patients. During the follow-up period (median 37 months; range 1-55 months), five patients developed local tumor progression and nine (29 %) died. Overall survival at 1, 2, and 3 years was 97, 82, and 74 %, respectively.
    Percutaneous RF ablation is a safe, feasible, and effective treatment for small malignant lung tumors.

    DOI: 10.1007/s11604-016-0557-z

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  • Radiofrequency Ablation of Lung Tumors Using a Multitined Expandable Electrode: Impact of the Electrode Array Diameter on Local Tumor Progression

    Hiroki Ihara, Hideo Gobara, Takao Hiraki, Toshiharu Mitsuhashi, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Junichi Soh, Shinichi Toyooka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY27 ( 1 ) 87 - 95   2016年1月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To retrospectively investigate the impact of the electrode array diameter on local tumor progression after lung radiofrequency ablation.
    Materials and Methods: This study included 651 lung tumors treated using multitined expandable electrodes and followed for 6 months. The mean long-axis tumor diameter was 12 mm +/- 7 (range, 2-42 mm). The difference between electrode array diameter and tumor diameter (DAT) was used to investigate the impact of the electrode array diameter. All tumors were classified into 2 groups according to various variables including DAT (>= 10 mm or < 10 mm). The primary technique efficacy rates were calculated using Kaplan-Meier analysis and compared between the 2 groups of each variable using the log-rank test. In addition, crude and multivariate multilevel survival analyses were performed by sequentially including DAT and the other variables in 5 models.
    Results: The median DAT for 651 tumors was 12 mm (range, 15 to 24 mm). The technique efficacy rate was significantly lower in the < 10 mm DAT group than in the >= 10 nun group (P < .001). In the crude and multivariate multilevel survival analyses, < 10 mm DAT was a significant risk factor for local progression in all models except model 5 (P = .067). In the >= 10 mm group, the technique efficacy rates were riot significantly different-between the 2 >= 10 min DAT subgroups (ICY to < 15 mm DAT vs >= 15 mm DAT).
    Conclusions: DAT is an important risk factor for local progression. We recommend an electrode that is >= 10 mm larger than the tumor diameter.

    DOI: 10.1016/j.jvir.2015.07.025

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  • CT fluoroscopy-guided preoperative short hook wire placement for small pulmonary lesions: evaluation of safety and identification of risk factors for pneumothorax

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Yusuke Matsui, Shinichiro Miyoshi, Susumu Kanazawa

    EUROPEAN RADIOLOGY26 ( 1 ) 114 - 121   2016年1月

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    記述言語:英語   出版者・発行元:SPRINGER  

    To retrospectively evaluate the safety of computed tomography (CT) fluoroscopy-guided short hook wire placement for video-assisted thoracoscopic surgery and the risk factors for pneumothorax associated with this procedure.
    We analyzed 267 short hook wire placements for 267 pulmonary lesions (mean diameter, 9.9 mm). Multiple variables related to the patients, lesions, and procedures were assessed to determine the risk factors for pneumothorax.
    Complications (219 grade 1 and 4 grade 2 adverse events) occurred in 196 procedures. No grade 3 or above adverse events were observed.
    Univariate analysis revealed increased vital capacity (odds ratio [OR], 1.518; P = 0.021), lower lobe lesion (OR, 2.343; P = 0.001), solid lesion (OR, 1.845; P = 0.014), prone positioning (OR, 1.793; P = 0.021), transfissural approach (OR, 11.941; P = 0.017), and longer procedure time (OR, 1.036; P = 0.038) were significant predictors of pneumothorax. Multivariate analysis revealed only the transfissural approach (OR, 12.171; P = 0.018) and a longer procedure time (OR, 1.048; P = 0.012) as significant independent predictors.
    Complications related to CT fluoroscopy-guided preoperative short hook wire placement often occurred, but all complications were minor. A transfissural approach and longer procedure time were significant independent predictors of pneumothorax.
    aEuro cent Complications related to CT fluoroscopy-guided preoperative short hook wire placement often occur.
    aEuro cent Complications are usually minor and asymptomatic.
    aEuro cent A transfissural approach and longer procedure time are significant independent predictors of pneumothorax.

    DOI: 10.1007/s00330-015-3815-z

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  • Disappearance of Renal Cysts Included in Ice Ball During Cryoablation of Renal-Cell Carcinoma

    Mitsuko Yodoya, Takao Hiraki, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Yoshihisa Masaoka, Jun Sakurai, Toshiharu Mitsuhashi, Hideo Gobara, Susumu Kanazawa

    Journal of Vascular and Interventional Radiology   2016年

  • Lymphography for filarial chyluria ; a case report

    N. Umakoshi, T. Hiraki, H. Fujiwara, T. Iguchi, H. Gobara, S. Kanazawa, J. Sakurai

    Japanese Journal of Clinical Radiology61 ( 9 ) 1169 - 1172   2016年

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  • Acute bowel injury due to cryoablation for renal cell carcinoma

    Hideo Gobara, Takao Hiraki, Toshihiro Iguchi, Hiroyasu Fujiwara, Takeshi Nagasaka, Hiroyuki Kishimoto, Takehiro Tanaka, Susumu Kanazawa

    Acta Medica Okayama, Acta. Medica Okayama, Acta medicinae Okayama, Acta medica Okayama70 ( 6 ) 511 - 514   2016年

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  • A case of focal bone marrow reconversion mimicking bone metastasis

    Takashi Tanaka, Hideo Gobara, Ryota Inai, Toshihiro Iguchi, Akihiro Tada, Shuhei Sato, Hiroyuki Yanai, Susumu Kanazawa

    Acta Medica Okayama, Acta. Medica Okayama, Acta medicinae Okayama, Acta medica Okayama70 ( 4 ) 285 - 290   2016年

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  • Radiation Exposure of Interventional Radiologists During Computed Tomography Fluoroscopy-Guided Renal Cryoablation and Lung Radiofrequency Ablation

    Yusuke Matsui, Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Takahiro Kawabata, Takatsugu Yamauchi, Takuya Yamaguchi, Susumu Kanazawa

    CardioVascular and Interventional Radiology, Cardiovascular Radiology   1 - 8   2016年

  • Single center prospective phase II trial of CT-guided radiofrequency ablation for pulmonary metastases from colorectal cancer (SCIRO-1401)

    Jun Sakurai, Yusuke Matsui, Takao Hiraki, Toshihiro Iguchi, Hiroyasu Fujiwara, Hideo Gobara, Toshiharu Mitsuhashi, Takeshi Nagasaka, Susumu Kanazawa

    Acta Medica Okayama, Acta. Medica Okayama, Acta medicinae Okayama, Acta medica Okayama70 ( 4 ) 317 - 322   2016年

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  • Safety of percutaneous cryoablation in patients with painful bone and soft tissue tumors

    Toshihiro Iguchi, Jun Sakurai, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Yusuke Matsui, Yoshihisa Masaoka, Susumu Kanazawa

    Acta Medica Okayama, Acta. Medica Okayama, Acta medicinae Okayama, Acta medica Okayama70 ( 4 ) 303 - 306   2016年

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  • Regression of a Pulmonary Arteriovenous Malformation after Acute Interstitial Nephritis

    Hideo Gobara, Takao Hiraki, Toshihiro Iguchi, Hiroyasu Fujiwara, Masashi Kitagawa, Nobuhisa Hanayama, Susumu Kanazawa

    INTERNAL MEDICINE55 ( 11 ) 1487 - 1489   2016年

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    記述言語:英語   出版者・発行元:JAPAN SOC INTERNAL MEDICINE  

    A 68-year-old woman was scheduled to undergo percutaneous embolization of a pulmonary arteriovenous malformation ( PAVM) to prevent a paradoxical embolic event. After contrast-enhanced computed tomography (CT) was performed to carefully evaluate the PAVM, she developed acute interstitial nephritis, which required steroid therapy. Moreover, her D-dimer level increased, which was suggestive of thrombus formation. After nine months, we noted that the affected vessels had markedly decreased in size, and the fistula had almost disappeared on unenhanced CT images. To our knowledge, this is the first case report to describe the regression of a PAVM, detected by CT, after the onset of acute interstitial nephritis.

    DOI: 10.2169/internalmedicine.55.5445

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  • Evaluation of Lung Radiofrequency Ablation With Dual-Energy Computed Tomography

    Koji Tomita, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Toshihiro Iguchi, Yusuke Matsui, Susumu Kanazawa

    Journal of Computer Assisted Tomography   2016年

  • Fever after lung radiofrequency ablation: Prospective evaluation of its incidence and associated factors

    Yoshihisa Masaoka, Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Shinichi Toyooka, Junichi Soh, Katsuyuki Kiura, Susumu Kanazawa

    EUROPEAN JOURNAL OF RADIOLOGY84 ( 11 ) 2202 - 2209   2015年11月

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    記述言語:英語   出版者・発行元:ELSEVIER IRELAND LTD  

    Purpose: To prospectively investigate the incidence of post-lung radiofrequency (RF) ablation fever as well as its associated factors, according to the grade of fever.
    Materials and Methods: A total of 56 patients who underwent 67 lung RF sessions were analyzed. Postablation fever (>= 37.0 degrees C) was graded according to the common toxicity criteria of adverse events v. 4.0. Fever >= 37.0 degrees C and <38.0 C was defined as grade 0 fever. The 67 RF sessions were divided into two groups according to the presence of post-ablation fever, and the factors associated with fever were determined using univariate and multivariate analyses. Subsequently, the RF sessions accompanied by post-ablation fever were further divided into two groups according to the grade of fever (grade 0 vs. grade >= 1), and the factors associated with the grade of fever were determined.
    Results: Grade 0, 1, and 2 fever accompanied 36 (54%), 11(16%), and 2 (3%) sessions, respectively. Post-ablation fever was significantly associated with larger ablated parenchymal volume (P=0.001) and development of pulmonary infiltration (P=0.004). Additionally, development of pulmonary infiltration (P=0.048) was also significantly and independently associated with higher grade of fever in the multivariate analysis.
    Conclusions: The incidences of grade 0, 1, and 2 post-ablation fever were 54%, 16%, and 3%, respectively. Larger ablated parenchymal volume and development of pulmonary infiltration were found to be associated with the development of post-ablation fever, with the latter being an independent factor associated with higher grade of fever. (C) 2015 Elsevier Ireland Ltd. All rights reserved.

    DOI: 10.1016/j.ejrad.2015.07.009

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  • Transosseous Route for CT Fluoroscopy-Guided Radiofrequency Ablation of Lung Tumors

    Toshihiro Iguchi, Takao Hiraki, Hiroaki Ishii, Hideo Gobara, Hiroyasu Fujiwara, Yusuke Matsui, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY26 ( 11 ) 1694 - 1698   2015年11月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To retrospectively evaluate radiofrequency (RF) ablation of lung tumors performed via the transosseous approach.
    Materials and Methods: Twelve lung tumors (mean diameter, 1.0 cm; range, 0.4-1.6 cm) in 12 patients were treated by RF ablation via a transscapular and/or transrib route with the use of a bone biopsy needle under computed tomographic fluoroscopy guidance. Therapeutic outcomes evaluated included feasibility, safety, and local efficacy. Complications were assessed based on the National Cancer Institute Common Terminology Criteria for Adverse Events, version 4.0.
    Results: The transosseous route was successfully employed in all patients, and the electrode was successfully advanced into all tumors with this approach. The mean distance of penetrated bone was 0.57 cm (range, 0.19-1.16 cm). Complications occurred in eight RF ablation sessions, including six grade 1 events (two cases of pneumothorax and one case each of asymptomatic rib fracture 6 mo after treatment, neuralgia, pulmonary hemorrhage, and hemothorax), two grade 2 events (pneumonia and high fever), and one grade 3 event (pneumothorax requiring pleurodesis). No adverse events of-grade >= 4 occurred. The mean and median tumor follow-up periods were 19.5 and 15.2 mo (range, 3.0-41.5 mo). Local progression occurred in two cases at 3 and 12 mo after treatment and Was successfully treated with a: second RF ablation procedure. The technique efficacy rates were 91.7% at 6 mo, 81.5% at 1 y, and 81.5% at 2 y.
    Conclusions: The transosseous approach was feasible in computed tomographic fluoroscopy guided RF ablation of select lung tumors when no other option was available.

    DOI: 10.1016/j.jvir.2015.08.012

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  • Tension Pneumopericardium as a Complication of Preoperative Localization of a Small Pulmonary Metastasis Using a Short Hook Wire and Suture System

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Hiromasa Yamamoto, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY38 ( 5 ) 1346 - 1348   2015年10月

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    記述言語:英語   出版者・発行元:SPRINGER  

    DOI: 10.1007/s00270-015-1122-3

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  • Simultaneous Multiple Preoperative Localizations of Small Pulmonary Lesions Using a Short Hook Wire and Suture System

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Yusuke Matsui, Seiichiro Sugimoto, Shinichi Toyooka, Takahiro Oto, Shinichiro Miyoshi, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY38 ( 4 ) 971 - 976   2015年8月

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    記述言語:英語   出版者・発行元:SPRINGER  

    The aim of the study was to retrospectively evaluate simultaneous multiple hook wire placement outcomes before video-assisted thoracoscopic surgery (VATS).
    Thirty-eight procedures were performed on 35 patients (13 men and 22 women; mean age, 59.9 years) with 80 lung lesions (mean diameter 7.9 mm) who underwent simultaneous multiple hook wire placements for preoperative localizations. The primary endpoints were technical success, complications, procedure duration, and VATS outcome; secondary endpoints included comparisons between technical success rates, complication rates, and procedure durations of the 238 single-placement procedures performed. Complications were also evaluated.
    In 35 procedures including 74 lesions, multiple hook wire placements were technically successful; in the remaining three procedures, the second target placement was aborted because of massive pneumothorax after the first placement. Although complications occurred in 34 procedures, no grade 3 or above adverse event was observed. The mean procedure duration was 36.4 +/- A 11.8 min. Three hook wires dislodged during patient transport to the surgical suite. Seventy-four successfully marked lesions were resected. Six lesions without hook wires were successfully resected after detection by palpation with an additional mini-thoracotomy or using subtle pleural changes as a guide. The complication rates and procedure durations of multiple-placement procedures were significantly higher (P = 0.04) and longer (P < 0.001) than those in the single-placement group, respectively, while the technical success rate was not significantly different (P = 0.051).
    Simultaneous multiple hook wire placements before VATS were clinically feasible, but increased the complication rate and lengthened the procedure time.

    DOI: 10.1007/s00270-014-1028-5

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  • Retrograde Renal Ablation via the Renal Vein as a New Treatment Option for Renovascular Hypertension

    Hiroyasu Fujiwara, Hideo Gobara, Takao Hiraki, Toshihiro Iguchi, Haruhito Adam Uchida, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY26 ( 6 ) 807 - 808   2015年6月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    DOI: 10.1016/j.jvir.2015.01.030

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  • Radiofrequency Ablation of Lung Metastases from Adenoid Cystic Carcinoma of the Head and Neck: Retrospective Evaluation of Nine Patients

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Yusuke Matsui, Shinichi Toyooka, Kazunori Nishizaki, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY26 ( 5 ) 703 - 708   2015年5月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To retrospectively evaluate the outcomes of radiofrequency (RF) ablation of lung metastases from head and neck adenoid cystic carcinoma (ACC).
    Materials and Methods: Nine patients (two men and seven women; mean age, 61.6 y) with 45 lung metastases (mean diameter, 1.1 cm; range, 0.4-2.7 cm) from head and neck ACC underwent RF ablation in 30 sessions. Primary endpoints were technical success, technique effectiveness, and procedural complications. Secondary endpoints included overall survival (OS).
    Results: RF ablation was technically successful for all 45 metastases. The median tumor follow-up period was 37.1 months (range, 12.9-128.3 mo). Local progression occurred in six tumors, two of which were treated again and subsequently showed complete response. Major complications (pneumothorax requiring chest tube placement) occurred in five sessions (16.7%). The median patient follow-up period was 61.6 months (range, 20.5-134.5 mo). Two patients died of disease progression at 38.9 and 61.6 months after RF ablation, respectively, whereas the other seven remained alive at the end of the study. OS rates from the initial RF ablation were 100% at 3 years and 83.3% at 5 years (mean survival time, 106.4 mo). OS rates from the treatment of the primary site were 100% at 5 years and 62.5% at 10 years (mean survival time, 210.1 mo).
    Conclusions: Radiofrequency ablation is an acceptable and effective local treatment for lung metastases from head and neck ACC. However, further study is needed to evaluate its effect on patient survival.

    DOI: 10.1016/j.jvir.2014.11.040

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  • Percutaneous Radiofrequency Ablation of Lung Cancer Presenting as Ground-Glass Opacity

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Yusuke Matsui, Junichi Soh, Shinichi Toyooka, Katsuyuki Kiura, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY38 ( 2 ) 409 - 415   2015年4月

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    記述言語:英語   出版者・発行元:SPRINGER  

    We retrospectively evaluated the outcomes of lung cancer patients presenting with ground-glass opacity (GGO) who received radiofrequency ablation (RFA).
    Sixteen patients (5 men and 11 women; mean age, 72.6 years) with 17 lung cancer lesions showing GGO (mean long axis diameter, 1.6 cm) underwent a total of 20 percutaneous computed tomography (CT) fluoroscopy-guided RFA sessions, including three repeated sessions for local progression. Lung cancer with GGO was defined as a histologically confirmed malignant pulmonary lesion with a GGO component accounting for > 50 % of the lesion on high-resolution CT. Procedure outcomes were evaluated.
    There were no major complications. Pneumothorax occurred in 15 of 20 treatment sessions: 14 were asymptomatic, and 1 required chest tube placement but resolved satisfactorily within 48 h. Minor pulmonary hemorrhage occurred in two and mild pneumonitis in one. The median tumor follow-up period was 61.5 (range 6.1-96.6) months. The effectiveness rates of the primary and secondary techniques were 100 and 100 % at 1 year, 93.3 and 100 % at 2 years, and 78.3 and 92.3 % at 3 years, respectively. The median patient follow-up period was 65.6 (range 6.1-96.6) months. One patient died owing to recurrent other cancer 11.7 months after RFA, whereas the other 15 remained alive. Overall survival and disease-specific survival rates were 93.3 and 100 % at 1 year and 93.3 and 100 % at 5 years, respectively.
    RFA for lung cancer with GGO was safe and effective, and resulted in promising survival rates.

    DOI: 10.1007/s00270-014-0926-x

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  • Long-Term Survival following Percutaneous Radiofrequency Ablation of Colorectal Lung Metastases

    Yusuke Matsui, Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Takeshi Nagasaka, Shinichi Toyooka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY26 ( 3 ) 303 - 310   2015年3月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To retrospectively evaluate long-term survival outcomes of radiofrequency (RF) ablation of colorectal lung metastases and evaluate factors associated with improved survival.
    Materials and Methods: Eighty-four patients (46 male and 38 female; median age, 65 y) with 172 colorectal lung metastases (median size, 1.2 cm) underwent 113 RF ablation sessions. Thirteen patients had viable extrapulmonary recurrences at the time of RF ablation. The primary endpoint was patient survival. Prognostic factors associated with survival were determined by univariate and multivariate analyses. Secondary endpoints were local tumor progression and adverse events (per National Cancer Institute Common Terminology Criteria for Adverse Events, version 4.0).
    Results: During follow-up (median duration, 37.5 mo), 36 patients (42.9%) died. The estimated overall survival (OS) rates were 95.2%, 65.0%, and 51.6% at 1, 3, and 5 years, respectively (median OS time, 67.0 mo). Multivariate analysis revealed that a carcinoembryonic antigen (CEA) level of at least 5 ng/mL before RE ablation (P = .03) and the presence of viable extrapulmonary recurrences at the time of RF ablation (P = .001) were independent negative prognostic factors. The local tumor progression rate was 14.0% (24 of 172 tumors). Grade 3 adverse events were observed after two sessions (1.8%), and grade 415 adverse events were not observed.
    Conclusions: RF ablation of colorectal lung metastases provided favorable long-term survival With a low incidence of severe adverse events. Independent prognostic factors were a high CEA level before RF ablation and the presence of viable extrapulmonary recurrences at the time of RF ablation.

    DOI: 10.1016/j.jvir.2014.11.013

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  • Transfissural Route Used for Preoperative Localization of Small Pulmonary Lesions with a Short Hook Wire and Suture System

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Yusuke Matsui, Seiichiro Sugimoto, Shinichi Toyooka, Takahiro Oto, Shinichiro Miyoshi, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY38 ( 1 ) 222 - 226   2015年2月

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    記述言語:英語   出版者・発行元:SPRINGER  

    We retrospectively evaluated the results of the transfissural route for preoperative localization with a short hook wire and suture system for video-assisted thoracoscopic surgery (VATS).
    Eleven patients with 11 tumors underwent CT-guided transfissural placement of a hook wire before VATS. This route was selected for all patients, because the distance between the tumor and interlobar fissure was much shorter than the required distance traversed using the conventional approach. Complications were evaluated using the National Cancer Institute Common Terminology Criteria for Adverse Events Version 4.0.
    The hook wire was successfully placed using the transfissural route in all but one case. Of these ten successful placements, two tumors needed a second puncture for optimal placement, because the CT scan showed that the first hook wire was not properly placed in the lung. In one patient, we did not attempt replacement after the first placement was incorrect. In ten successful procedures, the mean distance traversed in the parenchyma of the unaffected lung lobe was 27.9 mm. The distance between the pleura and placed hook wire was significantly shorter than the estimated distance between the pleura and hook wire using the conventional route (mean 16.3 vs. 40.9 mm; P = 0.0002). Grade 1 adverse events occurred (11 pneumothoraxes and 4 pulmonary hemorrhages). No grade 2 or higher adverse event was observed.
    The transfissural route used for preoperative localization before VATS is useful for selected patients because this route may allow for more limited lung parenchyma resection.

    DOI: 10.1007/s00270-014-0862-9

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  • Polycythemia Vera Diagnosed after Esophageal Variceal Rupture

    Yoshiyasu Kono, Akinobu Takaki, Hideo Gobara, Ken-ichi Matsuoka, Masato Nishino, Hiroyuki Okada, Kazuhide Yamamoto

    INTERNAL MEDICINE54 ( 18 ) 2395 - 2399   2015年

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    記述言語:英語   出版者・発行元:JAPAN SOC INTERNAL MEDICINE  

    Polycythemia vera (PV) is a chronic myeloproliferative neoplasm that leads to hyperviscosity and the risk of thrombosis. We encountered the case of a young male Filipino patient diagnosed with PV after the rupture of esophageal varices. The complete blood cell count showed a slight increase in white blood cells. An abdominal computed tomography scan disclosed splenomegaly and occlusion of the portal vein and collateral vessels. A blood examination demonstrated an increase in all three blood cell lines within three months. Based on the presence of severe hypercellularity of the bone marrow and positivity for the JAK2V617F mutation, we finally diagnosed the patient with PV.

    DOI: 10.2169/internalmedicine.54.4687

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  • Hepatic Intracystic Organizing Hematoma Mimicking Biliary Cystadenocarcinoma in a Patient with Polycystic Liver Disease

    Takashi Tanaka, Hideo Gobara, Koji Tomita, Takao Hiraki, Takehiro Tanaka, Susumu Kanazawa

    INTERNAL MEDICINE54 ( 16 ) 2001 - 2005   2015年

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    記述言語:英語   出版者・発行元:JAPAN SOC INTERNAL MEDICINE  

    Hepatic intracystic hemorrhage is a rare complication of polycystic liver diseases, such as autosomal dominant polycystic kidney disease (ADPKD). A hepatic cyst with mural nodules and septation may suggest the presence of a cystic malignancy, such as biliary cystadenocarcinoma. We herein report a case of hepatic intracystic hematoma with a mural nodule mimicking biliary cystadenocarcinoma in a patient with ADPKD. Hepatic intracystic hemorrhage with a mural nodule is a very rare occurrence. A fat-saturated T1-weighted magnetic resonance image may be useful for making an accurate diagnosis of intracystic hematoma.

    DOI: 10.2169/internalmedicine.54.4218

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  • レポート端末から電子カルテ端末への患者IDの受け渡しシステムの導入

    郷原英夫, 加藤勝也, 平木隆夫, 生口俊浩, 藤原寛康, 多田明博, 佐藤修平, 金澤 右

    映像情報Medical   2015年

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  • Hydrodissectionと腎癌に対する凍結治療

    メディックス   2015年

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  • 腎癌の診断とIVR治療

    画像診断   2015年

  • 肺癌のIVR前の画像診断

    生口俊浩, 郷原英夫, 平木隆夫, 藤原寛康, 金澤 右

    臨床画像   2015年

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  • Percutaneous Radiofrequency Ablation for Pulmonary Metastases from Esophageal Cancer: Retrospective Evaluation of 21 Patients

    Yusuke Matsui, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Toshihiro Iguchi, Yasuhiro Shirakawa, Toshiyoshi Fujiwara, Shinichi Toyooka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY25 ( 10 ) 1566 - 1572   2014年10月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To evaluate retrospectively Outcomes after radiofrequency (RF) ablation for pulmonary Metastases from esophageal cancer.
    Materials and Methods: This study included 21 consecutive patients who met inclusion. criteria (all men; mean age, 66.0 y) and had pulmonary metastases from esophageal cancer. There were 31 tumors (mean size, 1.7 cm) that Were treated with 27 planned ablation sessions. At the initial RF ablation sessions, 3 patients had viable extrapulmonary recurrences, and 18 patients had Viable recurrences confined to the lung. Primary study endpoints included patient survival and the determination of prognostic factors. Secondary endpoints included local efficacy and safety of the treatment. The log-rank test was used to identify prognostic factors. Adverse events Were evaluated according to,the National Cancer Institute Common Terminology Criteria for Adverse Events Version 4.0.
    Results: Median follow-up duration after the initial RF ablation was 22.4 months (range, 6.2-76.1 mo). Estimated overall survival rates were 85.7% at 1 year, 54.8% at 2 years, and 38.4% at 3 years after the initial RF ablation session. The presence of viable extrapulmonary recurrences at the initial RF ablation session was an unfavorable prognostic factor (P < .001). Local tumor progression was observed in 25.8% (8 of 31) of tumors and occurred 2.6-10.0 months (median, 4.8 mo) after RP ablation. Grade 3 adverse events occurred in 7.4% (2 of 27) of sessions, including pleural effusion requiring chest tube placement and pneumoderma requiring surgical intervention. No grade 4 or greater adverse events occurred.
    Conclusions: RF ablation is a promising treatment option for patients with pulmonary metastases from esophageal cancer.

    DOI: 10.1016/j.jvir.2014.06.030

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  • Risk Factors for Systemic Air Embolism as a Complication of Percutaneous CT-guided Lung Biopsy: Multicenter Case-control Study

    Hiroaki Ishii, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Hidefumi Mimura, Kotaro Yasui, Tetsuya Doke, Takashi Mukai, Hironori Kurokawa, Yoshitomo Ando, Soichiro Hase, Toshihiro Iguchi, Takayuki Yabuki, Kenichi Omae, Nobuhisa Tajiri, Toshiharu Mitsuhashi, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY37 ( 5 ) 1312 - 1320   2014年10月

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    記述言語:英語   出版者・発行元:SPRINGER  

    To determine risk factors for systemic air embolism by percutaneous computed tomography (CT)-guided lung biopsy.
    This case-control study used data from 2216 percutaneous lung biopsy procedures performed over 11 years at 12 institutions in Japan. Systemic air embolism was identified by retrospective review of CT images obtained during and immediately after the procedures. To fulfill our objective, multiple variables were compared between cases and controls with univariate analyses by using Student's t test and Fisher's exact test for numerical and categorical values, respectively. Multivariate logistic regression analysis was then performed using selected variables.
    Ten cases of systemic air embolism and 2,206 controls were identified. Univariate analyses showed that the lesions in the lower lobe (P = 0.025) and occurrence of parenchymal hemorrhage (P = 0.019) were significant risk factors. Multivariate analysis showed that the use of a larger biopsy needle was a significant risk factor (P = 0.014).
    Parenchymal hemorrhage during the procedure, lesions in the lower lobe, and the use of larger biopsy needles may be risk factors for systemic air embolism by percutaneous CT-guided lung biopsy. Our findings may provide clues toward minimizing the risk of this complication.

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  • Association between reperfusion and shrinkage percentage of the aneurysmal sac after embolization of pulmonary arteriovenous malformation: evaluation based on contrast-enhanced thin-section CT images

    Satoko Makimoto, Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Toshihiro Iguchi, Yusuke Matsui, Hidefumi Mimura, Susumu Kanazawa

    JAPANESE JOURNAL OF RADIOLOGY32 ( 5 ) 266 - 273   2014年5月

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    記述言語:英語   出版者・発行元:SPRINGER  

    To investigate an association between reperfusion and the percentage of shrinkage of the aneurysmal sac after embolization of pulmonary arteriovenous malformation (PAVM) and to determine the cutoff value of the shrinkage percentage for indicating reperfusion.
    Twenty-two PAVMs with completely embolized feeding arteries with coils were examined. The percentage of sac shrinkage and the presence of reperfusion were evaluated on computed tomography before and 1, 3, and 12 months after embolization. The percentages of sac shrinkage were compared between the occlusion and reperfusion groups. The receiver-operating characteristic (ROC) curve was generated to determine the diagnostic efficiency of reperfusion of PAVM by using shrinkage percentages.
    Reperfusion was seen in 14, 13, and 11 lesions at 1, 3, and 12 months, respectively. The mean percentage of sac shrinkage was significantly different between the two groups at 3 and 12 months. The area under the ROC curve was 0.991 at 3 months and 0.934 at 12 months. All 9 lesions with < 60 % sac shrinkage at 12 months showed reperfusion.
    The percentage of sac shrinkage was closely associated with reperfusion after embolization of PAVMs at 3 and 12 months. A shrinkage percentage of < 60 % at 12 months indicated reperfusion.

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  • A Case of Pulmonary Aspergilloma Treated with Radiofrequency Ablation

    Takao Hiraki, Hideo Gobara, Katsuya Kato, Hiroyasu Fujiwara, Toshihiro Iguchi, Yusuke Matsui, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY37 ( 2 ) 554 - 557   2014年4月

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)   出版者・発行元:SPRINGER  

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  • Radiofrequency ablation as treatment for pulmonary metastasis of colorectal cancer

    Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Susumu Kanazawa

    WORLD JOURNAL OF GASTROENTEROLOGY20 ( 4 ) 988 - 996   2014年1月

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    記述言語:英語   出版者・発行元:BAISHIDENG PUBL GRP CO LTD  

    Radiofrequency ablation (RFA) causes focal coagulation necrosis in tissue. Its first clinical application was reported in 2000, and RFA has since been commonly used in both primary and metastatic lung cancer. The procedure is typically performed using computed tomography guidance, and the techniques for introducing the electrode to the tumor are simple and resemble those used in percutaneous lung biopsy. The most common complication is pneumothorax, which occurs in up to 50% of procedures; chest tube placement for pneumothorax is required in up to 25% of procedures. Other severe complications, such as pleural effusion requiring chest tube placement, infection, and nerve injury, are rare. The local efficacy depends on tumor size, and local progression after RFA is not rare, occurring in 10% or more of patients. The local progression rate is particularly high for tumors > 3 cm. Repeat RFA may be used to treat local progression. Short-to mid-term survival after RFA appears promising and is approximately 85%-95% at 1 year and 45%-55% at 3 years. Long-term survival data are sparse. Better survival may be expected for patients with small metastasis, low carcinoembryonic antigen levels, and/or no extrapulmonary metastasis. The notable advantages of RFA are that it is simple and minimally invasive; preserves pulmonary function; can be repeated; and is applicable regardless of previous treatments. Its most substantial limitation is limited local efficacy. Although surgery is still the method of choice for treatment with curative intent, the ultimate application of RFA may be to replace metastasectomy for small metastases. Randomized trials comparing RFA with surgery are needed. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.

    DOI: 10.3748/wjg.v20.i4.988

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  • Radiofrequency ablation as treatment for pulmonary metastasis of colorectal cancer

    Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Susumu Kanazawa

    WORLD JOURNAL OF GASTROENTEROLOGY20 ( 4 ) 988 - 996   2014年1月

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    記述言語:英語   出版者・発行元:BAISHIDENG PUBL GRP CO LTD  

    Radiofrequency ablation (RFA) causes focal coagulation necrosis in tissue. Its first clinical application was reported in 2000, and RFA has since been commonly used in both primary and metastatic lung cancer. The procedure is typically performed using computed tomography guidance, and the techniques for introducing the electrode to the tumor are simple and resemble those used in percutaneous lung biopsy. The most common complication is pneumothorax, which occurs in up to 50% of procedures; chest tube placement for pneumothorax is required in up to 25% of procedures. Other severe complications, such as pleural effusion requiring chest tube placement, infection, and nerve injury, are rare. The local efficacy depends on tumor size, and local progression after RFA is not rare, occurring in 10% or more of patients. The local progression rate is particularly high for tumors > 3 cm. Repeat RFA may be used to treat local progression. Short-to mid-term survival after RFA appears promising and is approximately 85%-95% at 1 year and 45%-55% at 3 years. Long-term survival data are sparse. Better survival may be expected for patients with small metastasis, low carcinoembryonic antigen levels, and/or no extrapulmonary metastasis. The notable advantages of RFA are that it is simple and minimally invasive; preserves pulmonary function; can be repeated; and is applicable regardless of previous treatments. Its most substantial limitation is limited local efficacy. Although surgery is still the method of choice for treatment with curative intent, the ultimate application of RFA may be to replace metastasectomy for small metastases. Randomized trials comparing RFA with surgery are needed. (C) 2014 Baishideng Publishing Group Co., Limited. All rights reserved.

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  • 骨軟部腫瘍に対する凍結治療

    郷原英夫, 平木隆夫, 生口俊浩, 藤原寛康, 松井裕輔, 金澤 右

    映像情報メディカル   2014年

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  • 肺癌のRFA

    平木隆夫, 郷原英夫, 生口俊浩, 藤原寛康, 松井裕輔, 金澤 右

    臨床放射線   2014年

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  • 岡山大学病院IVRセンターにおける電子情報環境

    郷原英夫, 平木隆夫, 生口俊浩, 藤原寛康, 松井裕輔, 金澤 右

    映像情報Medical   2014年

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  • 腎凍結療法の実際

    藤原寛康, 平木隆夫, 郷原英夫, 生口俊浩, 松井裕輔, 金澤 右

    Rad Fan   2014年

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  • Radiofrequency Ablation for Early-Stage Nonsmall Cell Lung Cancer

    Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Susumu Kanazawa

    BIOMED RESEARCH INTERNATIONAL   2014年

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    記述言語:英語   掲載種別:書評論文,書評,文献紹介等   出版者・発行元:HINDAWI PUBLISHING CORPORATION  

    This review examines studies of radiofrequency ablation (RFA) of nonsmall cell lung cancer (NSCLC) and discusses the role of RFA in treatment of early-stage NSCLC. RFA is usually performed under local anesthesia with computed tomography guidance. RFA-associated mortality, while being rare, can result from pulmonary events. RFA causes pneumothorax in up to 63% of cases, although pneumothorax requiring chest drainage occurs in less than 15% of procedures. Other severe complications are rare. After RFA of stage I NSCLC, 31-42% of patients show local progression. The 1-, 2-, 3-, and 5-year overall survival rates after RFA of stage I NSCLC were 78% to 100%, 53% to 86%, 36% to 88%, and 25% to 61%, respectively. The median survival time ranged from 29 to 67 months. The 1-, 2-, and 3-year cancer-specific survival rates after RFA of stage I NSCLC were 89% to 100%, 92% to 93%, and 59% to 88%, respectively. RFA has a higher local failure rate than sublobar resection and stereotactic body radiation therapy (SBRT). Therefore, RFA may currently be reserved for early-stage NSCLC patients who are unfit for sublobar resection or SBRT. Various technologies are being developed to improve clinical outcomes of RFA for early-stage NSCLC.

    DOI: 10.1155/2014/152087

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  • 軟部動静脈奇形の塞栓術

    三村秀文, 芝本健太郎, 宗田由子, 児島克英, 松井裕輔, 藤原寛康, 平木隆夫, 郷原英夫, 金澤 右

    臨床画像   2014年

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  • 静脈奇形の硬化療法

    三村秀文, 芝本健太郎, 宗田由子, 児島克英, 松井裕輔, 藤原寛康, 平木隆夫, 郷原英夫, 金澤 右

    臨床放射線   2014年

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  • Creation of an artificial hydromediastinum for radiofrequency ablation of lung tumor: a report of two cases.

    Takao Hiraki, Hideo Gobara, Toshihiro Iguchi, Hiroyasu Fujiwara, Yusuke Matsui, Susumu Kanazawa

    Journal of Vascular and Interventional Radiology   2014年

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  • Bleeding into a pulmonary cyst caused by pulmonary radiofrequency ablation

    Ryotaro Kishi, Hidefumi Mimura, Takao Hiraki, Hideo Gobara, Mayu Uka, Shinichi Toyooka, Susumu Kanazawa

    Journal of Vascular and Interventional Radiology24 ( 7 ) 1069 - 1071   2013年7月

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)  

    DOI: 10.1016/j.jvir.2013.03.023

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  • Ⅹ 肺癌の治療戦略 インターベンショナルラジオロジーによる治療 肺癌のラジオ波焼灼療法

    金澤 右, 郷原英夫, 平木隆夫

    日本臨牀 最新肺癌学ー基礎と臨床の最新研究動向ー   2013年

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  • Ablationの現状と未来 6.不可逆電気穿孔法

    藤原寛康, 平木隆夫, 石井裕朗, 郷原英夫, 金澤 右

    IVR会誌   2013年

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  • Ablationの現状と未来 4.肺癌に対するラジオ波焼灼療法

    平木隆夫, 郷原英夫, 藤原寛康, 金澤 右

    IVR会誌   2013年

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  • The Maximum Standardized Uptake Value Is More Reliable Than Size Measurement in Early Follow-up to Evaluate Potential Pulmonary Malignancies Following Radiofrequency Ablation.

    Alafate A, Shinya T, Okumura Y, Sato S, Hiraki T, Ishii H, Gobara H, Kato K, Fujiwara T, Miyoshi S, Kaji M, Kanazawa S

    Acta Med Okayama.   2013年

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  • 静脈奇形のポリドカノールを用いた硬化療法

    三村秀文, 松井裕輔, 宗田由子, 道下宣成, 藤原寛康, 平木隆夫, 郷原英夫, 金澤 右

    IVR会誌   2013年

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  • Oligometastastases,oligo-recurrenceヘのRFAの応用

    平木隆夫, 郷原英夫, 生口俊浩, 藤原寛康, 松井裕輔, 金澤 右

    臨床放射線   2013年

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  • 岡山大学病院でのCTガイドの現況とMRIガイドの今後

    郷原英夫

    新医療   2013年

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  • アブレーション:腎癌 -凍結療法を中心に-

    郷原英夫, 平木隆夫, 藤原寛康, 生口俊浩, 松井裕輔, 金澤 右

    臨床画像   2013年

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  • Lung cancer ablation: Complications

    Takao Hiraki, Hideo Gobara, Hiroyasu Fujiwara, Hiroaki Ishii, Koji Tomita, Mayu Uka, Satoko Makimoto, Susumu Kanazawa

    Seminars in Interventional Radiology30 ( 2 ) 169 - 175   2013年

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    記述言語:英語   出版者・発行元:Thieme Medical Publishers, Inc.  

    Although radiofrequency ablation for lung cancer is generally safe (with a mortality rate &lt
    1%), it may cause various complications. Common complications include pneumothorax, pleural effusion, and parenchymal hemorrhage. Although most complications can be treated conservatively or with minimal therapy, physicians should be aware of rare but serious complications. Potentially fatal complications include massive hemorrhage, intractable pneumothorax due to bronchopleural fistula, pulmonary artery pseudoaneurysm, systemic air embolism, and pneumonitis. Other serious complications include injury to the nearby tissues (e.g., brachial nerve plexus, phrenic nerve, diaphragm, and chest wall), needle tract seeding, lung abscess, empyema, and skin burn. Although cavitation of the ablation zone is usually insignificant clinically, such a cavity occasionally ruptures, leading to pneumothorax and bleeding. Cavities may also serve as a scaffold for fungal colonization. Precautions to minimize risk should be taken whenever possible. Nevertheless, serious complications may occur, and thus physicians should be aware of the appropriate treatments for these complications. This article reviews complications associated with lung cancer ablation. © 2013 by Thieme Medical Publishers, Inc.

    DOI: 10.1055/s-0033-1342958

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  • イレウスにて発症した心嚢内ヘルニアの1例

    槇本怜子, 郷原英夫, 櫻間教文, 田邊俊介, 野間和広, 白川靖博, 金澤 右

    臨床放射線   2013年

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  • Influence of Radiofrequency Ablation of Lung Cancer on Pulmonary Function

    Akihiro Tada, Takao Hiraki, Toshihiro Iguchi, Hideo Gobara, Hidefumi Mimura, Shinichi Toyooka, Katsuyuki Kiura, Toshihide Tsuda, Toshiharu Mitsuhashi, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY35 ( 4 ) 860 - 867   2012年8月

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    記述言語:英語   出版者・発行元:SPRINGER  

    The purpose of this study was to evaluate altered pulmonary function retrospectively after RFA.
    This retrospective study comprised 41 ablation sessions for 39 patients (22 men and 17 women; mean age, 64.8 years). Vital capacity (VC) and forced expiratory volume in 1 s (FEV1) at 1 and 3 months after RFA were compared with the baseline (i.e., values before RFA). To evaluate the factors that influenced impaired pulmonary function, univariate analysis was performed by using multiple variables. If two or more variables were indicated as statistically significant by univariate analysis, these variables were subjected to multivariate analysis to identify independent factors.
    The mean VC and FEV1 before RFA and 1 and 3 months after RFA were 3.04 and 2.24 l, 2.79 and 2.11 l, and 2.85 and 2.13 l, respectively. The values at 1 and 3 months were significantly lower than the baseline. Severe pleuritis after RFA was identified as the independent factor influencing impaired VC at 1 month (P = 0.003). For impaired FEV1 at 1 month, only severe pleuritis (P = 0.01) was statistically significant by univariate analysis. At 3 months, severe pleuritis (VC, P = 0.019; FEV1, P = 0.003) and an ablated parenchymal volume a parts per thousand yen20 cm(3) (VC, P = 0.047; FEV1, P = 0.038) were independent factors for impaired VC and FEV1.
    Pulmonary function decreased after RFA. RFA-induced severe pleuritis and ablation of a large volume of marginal parenchyma were associated with impaired pulmonary function.

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  • A Case of Delayed Massive Hemothorax Caused by the Rupture of a Pulmonary Artery Pseudoaneurysm after Radiofrequency Ablation of Lung Tumors

    Junichi Soh, Shinichi Toyooka, Hideo Gobara, Takao Hiraki, Seiichiro Sugimoto, Masaomi Yamane, Takahiro Oto, Susumu Kanazawa, Shinichiro Miyoshi

    JAPANESE JOURNAL OF CLINICAL ONCOLOGY42 ( 7 ) 646 - 649   2012年7月

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    記述言語:英語   出版者・発行元:OXFORD UNIV PRESS  

    Radiofrequency ablation has been applied as a minimally invasive therapy for the local control of lung tumors, including primary and metastatic neoplasms. Hemorrhagic complications after radiofrequency ablation can usually be treated conservatively, but such complications can be massive and fatal in some cases. In this paper, we report the rare case of delayed massive hemothrax caused by the rupture of a pulmonary artery pseudoaneurysm after lung radiofrequency ablation that was treated using transcatheter coil embolization followed by a left lower lobectomy. A 75-year-old woman underwent radiofrequency ablation for the treatment of a metastatic lung tumor in the left lower lobe arising from a colorectal carcinoma located close to a branch of the pulmonary artery. Thirty-six hours later, hemothorax and hemorrhagic shock occurred as a result of a ruptured pulmonary artery pseudoaneurysm and radiofrequency ablation-induced damage to the interlobular pleura. After transcatheter coil embolization of the pulmonary artery pseudoaneurysm, she recovered from a state of shock and a left lower lobectomy was performed. Histological findings revealed the presence of residual tumor cells in the ablated lung tumor. The postoperative course was uneventful, and no evidence of recurrence of the primary disease was seen at 1 year after the surgery. Although hemothorax secondary to the rupture of a pulmonary artery pseudoaneurysm after lung radiofrequency ablation is a rare complication, it should be recognized as a serious potential complication of lung radiofrequency ablation for a tumor located close to the pulmonary artery branch.

    DOI: 10.1093/jjco/hys068

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  • Phrenic Nerve Injury after Radiofrequency Ablation of Lung Tumors: Retrospective Evaluation of the Incidence and Risk Factors

    Yusuke Matsui, Takao Hiraki, Hideo Gobara, Mayu Uka, Yoshihisa Masaoka, Akihiro Tada, Shinichi Toyooka, Toshiharu Mitsuhashi, Hidefumi Mimura, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY23 ( 6 ) 780 - 785   2012年6月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To retrospectively investigate the incidence of and risk factors for phrenic nerve injury after radiofrequency (RF) ablation of lung tumors.
    Materials and Methods: The study included 814 RF ablation procedures of lung tumors. To evaluate the development of phrenic nerve injury, chest radiographs obtained before and after the procedure were examined. Phrenic nerve injury was assumed to have developed if the diaphragmatic level was elevated after the procedure. To identify risk factors for phrenic nerve injury, multiple variables were compared between cases of phrenic nerve injury and randomly selected controls by using univariate analyses. Multivariate analysis was then performed to identify independent risk factors.
    Results: Evaluation of phrenic nerve injury from chest radiographs was possible after 786 procedures. Evidence of phrenic nerve injury developed after 10 cases (1.3%). Univariate analysis revealed that larger tumor size >= 20 mm; P = .014), proximity of the phrenic nerve to the tumor (< 10 mm; P < .001), the use of larger electrodes (array diameter or noninsulated tip length >= 3 cm; P = .001), and higher maximum power applied during ablation (>= 100 W; P < .001) were significantly associated with the development of phrenic nerve injury. Multivariate analysis demonstrated that the proximity of the phrenic nerve to the tumor (< 10 mm; P < .001) was a significant independent risk factor.
    Conclusions: The incidence of phrenic nerve injury after RF ablation was 1.3%. The proximity of the phrenic nerve to the tumor was an independent risk factor for phrenic nerve injury.

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  • Presence of EGFR mutation in pathologically non-malignant specimens from computed tomography-guided lung needle biopsies

    Tsuyoshi Ueno, Junichi Soh, Takao Hiraki, Hiroaki Asano, Koichi Ichimura, Kentaro Shibamoto, Hideo Gobara, Susumu Kanazawa, Shinichi Toyooka, Shinichiro Miyoshi

    ONCOLOGY LETTERS3 ( 2 ) 401 - 404   2012年2月

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    記述言語:英語   出版者・発行元:SPANDIDOS PUBL LTD  

    Activating mutations of the epidermal growth factor receptor (EGFR) gene are characteristic of non-small cell lung cancer (NSCLC). EGFR mutations were previously detected in histologically normal lung tissue around NSCLC tumors. Computed tomography-guided lung needle biopsy (CTNB) is an accurate and useful technique for the diagnosis of lung tumors. However, pathologically non-malignant cases occasionally become apparent following lung tumor resection. In this study, we determined the EGFR mutational status of lung tumors diagnosed as non-malignant in CTNB specimens, but diagnosed as NSCLC following surgical resection. Between 2000 and 2008, 1,109 CTNBs were performed at Okayama University Hospital. Among them, 15 cases were initially diagnosed as non-malignant by CTNB, but diagnosed as NSCLC following surgical resection as a result of a high likelihood of malignancy by clinical findings. Twelve paired DNAs of CTNB and corresponding resected specimens were available to examine the EGFR mutational status using a mutant-enriched PCR assay. EGFR mutations were detected in one out of 12 CTNB specimens and three of the corresponding resected tumors. This case harbored the same EGFR mutation in the CTNB specimen and resected tumor, but not in the distant corresponding nonmalignant lung tissue. Our results indicated that the detection of EGFR mutations may therefore aid the diagnosis of NSCLC in pathologically non-malignant CTNB specimens.

    DOI: 10.3892/ol.2011.471

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  • Bronchiolitis Obliterans Organizing Pneumonia after Radiofrequency Ablation of Lung Cancer: Report of Three Cases

    Takao Hiraki, Hideo Gobara, Katsuya Kato, Shinichi Toyooka, Hidefumi Mimura, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY23 ( 1 ) 126 - 130   2012年1月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    The present report describes three cases of a bronchiolitis obliterans organizing pneumonia (BOOP)-like reactive pneumonitis following radiofrequency (RF) ablation for lung cancer. The incidence of BOOP-like reactive pneumonitis after RF ablation at the authors' institution was estimated to be approximately 0.4% (three of 840 sessions). The patients presented with nonspecific symptoms. Computed tomography images showed consolidation or ground-glass opacity in a peripheral-dominant distribution and/or patchy air-space opacities. The disease was nonresponsive to antibiotic therapy but responded favorably to pulse therapy of steroids. BOOP-like reactive pneumonitis should be recognized as a complication following lung RF ablation.

    DOI: 10.1016/j.jvir.2011.09.011

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  • ISSVA分類とその臨床的意義.

    三村秀文, 松井裕輔, 藤原寛康, 平木隆夫, 郷原英夫, 宗田由子, 道下宣成, 木股敬裕, 金澤 右

    画像診断32 ( 10 ) 974 - 985   2012年

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  • Diaphragmatic Hernia after Percutaneous Radiofrequency Ablation of Lung Tumor

    Takao Hiraki, Hideo Gobara, Yoshihisa Masaoka, Shinichi Toyooka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY22 ( 12 ) 1777 - 1778   2011年12月

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE INC  

    DOI: 10.1016/j.jvir.2011.08.014

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  • A Case of Renal Transcatheter Arterial Embolization with Ethanol in Autosomal Dominant Polycystic Kidney Disease for Volume Reduction

    Takashi Mukai, Hidefumi Mimura, Hideo Gobara, Mitsuharu Shimizu, Harutaka Niiya, Susumu Kanazawa

    ACTA MEDICA OKAYAMA65 ( 5 ) 347 - 351   2011年10月

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    記述言語:英語   出版者・発行元:OKAYAMA UNIV MED SCHOOL  

    We report herein the case of a 76-year-old woman with autosomal dominant polycystic kidney disease (ADPKD) and chronic renal failure resulting in intractable abdominal distension and anorexia. Computed tomography (CT) showed enlarged and cystic kidneys. We performed transcatheter arterial embolization (TAE) for renal arteries with ethanol. Absolute ethanol with iodinated contrast medium or Lipiodol was delivered into both renal arteries. The patient's low-grade fever subsided in 5 days, and no other complication occurred. The sensation of abdominal distension diminished approximately 1 month after embolization. A progressive decrease in kidney size was observed soon after embolization. The percentage of the decrement of kidney size was approximately 50% after 17 months. These results indicate that renal TAE with ethanol is a safe, cost-effective, and minimally invasive technique to reduce kidney size in symptomatic ADPKD patients.

    DOI: 10.18926/AMO/47018

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  • Radiofrequency Ablation of Lung Cancer at Okayama University Hospital: A Review of 10 Years of Experience

    Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Shinichi Toyooka, Hiroyasu Fujiwara, Kotaro Yasui, Yoshifumi Sano, Toshihiro Iguchi, Jun Sakurai, Nobuhisa Tajiri, Takashi Mukai, Yusuke Matsui, Susumu Kanazawa

    ACTA MEDICA OKAYAMA65 ( 5 ) 287 - 297   2011年10月

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    記述言語:英語   掲載種別:書評論文,書評,文献紹介等   出版者・発行元:OKAYAMA UNIV MED SCHOOL  

    The application of radiofrequency ablation for the treatment of lung cancer by our group at Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences began in June 2001, and in the present report, we review our 10-year experience with this treatment modality at Okayama University Hospital. The local efficacy of radiofrequency ablation for the treatment of lung cancer depends on tumor size and the type of electrode used, but not on tumor type. An important factor for the prevention of local failure may be the acquisition of an adequate ablative margin. The combination of embolization and radiation therapy enhances the local efficacy. Local failure may be salvaged by repeating the radiofrequency ablation, particularly in small tumors. Survival rates after radiofrequency ablation are quite promising for patients with clinical stage I non-small cell lung cancer and pulmonary metastasis from colorectal cancer, hepatocellular carcinoma, and renal cell carcinoma. The complications caused by radiofrequency ablation can be treated conservatively in the majority of cases. However, attention should be paid to rare but serious complications. This review shows that radiofrequency ablation is a promising treatment for patients with lung cancer.

    DOI: 10.18926/AMO/47010

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  • Percutaneous radiofrequency ablation of clinical stage I non-small cell lung cancer

    Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Yusuke Matsui, Shinichi Toyooka, Susumu Kanazawa

    JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY142 ( 1 ) 24 - 30   2011年7月

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    記述言語:英語   出版者・発行元:MOSBY-ELSEVIER  

    Objective: This study aimed at retrospectively evaluating the outcomes of radiofrequency ablation of clinical stage I non-small cell lung cancer.
    Methods: This study was carried out on 50 nonsurgical candidates (29 men and 21 women; mean age, 74.7 years) with clinical stage I (IA, n = 38; IB, n = 12) histologically proven non-small cell lung cancer. A total of 52 tumors were treated with 52 ablation sessions. Radiofrequency ablation was performed percutaneously under computed tomography fluoroscopic guidance. The outcomes of radiofrequency ablation were evaluated, including toxicity, local efficacy, and patient survival. Toxicity was evaluated using the National Cancer Institute Common Terminology Criteria for Adverse Events Version 4.0. Local efficacy was evaluated by using computed tomography scan with a contrast medium. The overall, cancer-specific, and disease-free survivals were estimated with Kaplan-Meier analysis.
    Results: Grade 2 and 3 adverse events occurred after 6 (12%) and 3 (6%) of the 52 sessions, respectively. The median follow-up period was 37 months. Local progression was observed in 16 (31%) of the 52 tumors. The median survival time was 67 months. The overall, cancer-specific, and disease-free survivals were 94%, 100%, and 82% at 1 year, 86%, 93%, and 64% at 2 years, and 74%, 80%, and 53% at 3 years, respectively.
    Conclusions: Radiofrequency ablation of clinical stage I non-small cell lung cancer was minimally invasive and provided promising patient survival, although the local efficacy needs to be improved. (J Thorac Cardiovasc Surg 2011;142:24-30)

    DOI: 10.1016/j.jtcvs.2011.02.036

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  • Percutaneous Radiofrequency Ablation for Pulmonary Metastases from Hepatocellular Carcinoma: Results of a Multicenter Study in Japan

    Takao Hiraki, Koichiro Yamakado, Osamu Ikeda, Toshiyuki Matsuoka, Toshio Kaminou, Takuji Yamagami, Hideo Gobara, Hidefumi Mimura, Koichi Kawanaka, Kan Takeda, Yasuyuki Yamashita, Yuichi Inoue, Toshihide Ogawa, Tsunehiko Nishimura, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY22 ( 6 ) 741 - 748   2011年6月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    Purpose: To retrospectively evaluate technical success, effectiveness, complications, patient survival, and prognostic factors with percutaneous radiofrequency (RF) ablation for pulmonary metastases resulting from hepatocellular carcinoma (HCC).
    Materials and Methods: Thirty-two patients from six institutions were included, with a total of 83 pulmonary metastases treated in 65 sessions. RF ablation was always performed percutaneously with computed tomography (CT) guidance. Primary endpoints were technical success and technique effectiveness. Technique effectiveness was evaluated based on sequential follow-up CT images. Secondary study endpoints were complications, patient survival, and determination of prognostic factors. Complications were classified as major or minor. Prognostic factors were determined by analyzing multiple variables with the log-rank test.
    Results: Technical success rate was 100%. Primary technique effectiveness rates were 92% each at 1, 2, and 3 years. Major and minor complications occurred after 16 (25%) and 23 (35%) of the 65 sessions, respectively. The median follow-up period was 20.5 months. Overall survival rates were 87% at 1 year and 57% each at 2 and 3 years (median and mean survival times, 37.7 mo and 43.2 mo, respectively). Significantly better survival rates were obtained in cases of (i) no viable intrahepatic recurrence (P < .001), (ii) Child-Pugh class A disease (P < .001), (iii) absence of liver cirrhosis (P < .001), (iv) absence of hepatitis C virus infection (P = .006), and (v) alpha-fetoprotein level of 10 ng/mL or lower (P = .007) at the time of RF ablation.
    Conclusions: RF ablation appears effective, with an acceptable safety profile, in selected patients with pulmonary metastases resulting from HCC.

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  • Technique for Creation of Artificial Pneumothorax for Pain Relief during Radiofrequency Ablation of Peripheral Lung Tumors: Report of Seven Cases

    Takao Hiraki, Hideo Gobara, Kentaro Shibamoto, Hidefumi Mimura, Yuko Soda, Mayu Uka, Yoshihisa Masaoka, Shinichi Toyooka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY22 ( 4 ) 503 - 506   2011年4月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    This report describes seven cases in which a pneumothorax was artificially created for relief from severe pain that occurred during radiofrequency (RF) ablation of peripheral lung tumors. In this procedure the multitined probe surrounding the legion was advanced into the chest, displaoing the tines and the peripheral tumor away from the parietal pleura and the chest wall and resulting in pain relief in one patient; in the remaining patients, an intravenous catheter was also introduced, followed by the administration of carbon dioxide (CO2) into the space between the tumor and the parietal pleura. The pain decreased-considerably-immediately after this procedure. No complication related to the creation of the artificial pneumothorax was observed. Creation of an artificial pneumothorax is a safe and effective method for pain relief.

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  • Role of Computed Tomography Fluoroscopy-Guided Cutting Needle Biopsy of Lung Lesions After Transbronchial Examination Resulting in Negative Diagnosis

    Yusuke Matsui, Takao Hiraki, Hidefumi Mimura, Hideo Gobara, Daisaku Inoue, Tatsuhiko Iishi, Shinichi Toyooka, Susumu Kanazawa

    CLINICAL LUNG CANCER12 ( 1 ) 51 - 55   2011年1月

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    記述言語:英語   出版者・発行元:CIG MEDIA GROUP, LP  

    Introduction: Computed tomography (CT)-guided lung biopsy is occasionally used for the lesions that were diagnosed as nonmalignant by transbronchial examination despite the fact that other clinical data suggested those as malignant. The purpose of this study is to evaluate the outcomes of CT fluoroscopy-guided cutting needle biopsy of lung lesions after transbronchial examination resulting in negative diagnosis. Patients and Methods: We retrospectively evaluated the outcomes of CT fluoroscopy-guided lung biopsy for 351 lesions (mean size, 2.8 cm) that were found to be nonmalignant by transbronchial examination. Diagnostic yield, including sensitivity and specificity for the diagnosis of malignancy, positive predictive value (PPV), negative predictive value (NPV), and accuracy were calculated. Various variables were analyzed to determine the factors for diagnostic failure. Results: The biopsy result was nondiagnostic, true-positive, true-negative, false-positive, or false-negative for 2, 262, 70, 0, or 17 lesions, respectively. Thus, the sensitivity, specificity, PPV, NPV, and accuracy of CT fluoroscopy-guided cutting needle biopsy was found to be 93% (262/281), 100% (70/70), 100% (262/262), 80% (70/87), and 94% (332/351), respectively. There was no significant risk factor for diagnostic failure. Conclusion: Computed tomography fluoroscopy-guided cutting needle lung biopsy is a useful technique to correct or confirm negative diagnosis by transbronchial examination.

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  • 非小細胞肺癌の治療後変化

    奥村能啓, 新家崇義, 宗田由子, 生口俊浩, 小林 満, 檜垣文代, 平木隆夫, 郷原英夫, 加藤勝也, 佐藤修平, 加地充昌, 金澤 右

    臨床画像27 ( 12 ) 1446 - 1455   2011年

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  • The usefulness of pre-radiofrequency ablation SUV(max) in 18F-FDG PET/CT to predict the risk of a local recurrence of malignant lung tumors after lung radiofrequency ablation.

    Harada S, Sato S, Suzuki E, Okumura Y, Hiraki T, Gobara H, Mimura H, Kanazawa S, Kaji M, Fujiwara T

    Acta Med Okayama65 ( 6 ) 347 - 351   2011年

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  • 腎RFA 適応と合併症

    三村秀文, 郷原英夫, 平木隆夫, 藤原寛康, 芝本健太郎, 金澤 右

    Jpn J Intervent Radiol26 ( 4 ) 708 - 411   2011年

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  • Brachial Nerve Injury Caused by Percutaneous Radiofrequency Ablation of Apical Lung Cancer: A Report of Four Cases

    Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Yoshifumi Sano, Shinichi Toyooka, Kentaro Shibamoto, Ryotaro Kishi, Mayu Uka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY21 ( 7 ) 1129 - 1133   2010年7月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    The present report describes four cases of brachial nerve injury caused by percutaneous radiofrequency (RF) ablation of lung cancer. All the tumors were located in the lung apex. The patients developed symptoms indicative of a low brachial plexus injury during RF ablation or as long as 7 days afterward. These symptoms partially receded over time. The indications of RF ablation in patients with apical lung cancer should be carefully determined because of the risk of brachial nerve injury associated with the procedure.

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  • Pneumopericardium as a Complication of CT-guided Lung Biopsy

    Takao Hiraki, Ryota Inai, Hidefumi Mimura, Hideo Gobara, Kentaro Shibamoto, Ryotaro Kishi, Mayu Uka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY21 ( 7 ) 1136 - 1138   2010年7月

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE INC  

    DOI: 10.1016/j.jvir.2010.03.017

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  • Pulmonary Artery Pseudoaneurysm Related to Radiofrequency Ablation of Lung Tumor

    Jun Sakurai, Hidefumi Mimura, Hideo Gobara, Takao Hiraki, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY33 ( 2 ) 413 - 416   2010年4月

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    記述言語:英語   出版者・発行元:SPRINGER  

    We describe a case of pulmonary artery (PA) pseudoaneurysm related to radiofrequency ablation (RFA) of lung tumor. We performed RFA for a pulmonary epithelioid hemangioendothelioma directly adjacent to a branch of the PA. Seventeen days later, the patient complained of hemoptysis. A chest CT image revealed PA pseudoaneurysm. Transcatheter coil embolization was performed 59 days after RFA. Although PA pseudoaneurysm is rare, with an incidence of 0.2% (1/538 sessions) at our institution, it should be recognized as a risk when treating lung tumors adjacent to a branch of the PA.

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  • Does tumor type affect local control by radiofrequency ablation in the lungs?

    Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Yoshifumi Sano, Toshihide Tsuda, Toshihiro Iguchi, Hiroyasu Fujiwara, Ryotaro Kishi, Yusuke Matsui, Susumu Kanazawa

    EUROPEAN JOURNAL OF RADIOLOGY74 ( 1 ) 136 - 141   2010年4月

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    記述言語:英語   出版者・発行元:ELSEVIER IRELAND LTD  

    Objective: : To retrospectively evaluate the effect of tumor type on local control by radiofrequency ablation in the lungs.
    Materials and methods: : This study included 252 lung tumors (mean size, 13.5 mm) in 105 patients (73 men and 32 women; mean age, 66.6 years) who underwent radiofrequency ablation with a multitined expandable electrode. Those tumors comprised five tumor types: primary lung cancer (n = 35) and pulmonary metastases from colorectal cancer (n = 117), lung cancer (n = 23), renal cell carcinoma (n = 49), and hepatocellular carcinoma (n = 28). Local control was evaluated with contrast-enhanced computed tomography. The overall local control rates were estimated as well as those for each tumor type using the Kaplan-Meier analysis. Local control rates for a given tumor type were compared with those for the four other types. Then, multivariate multilevel analysis was performed using the variables of tumor type, tumor size, contact with a vessel or bronchus, and procedure period.
    Results: : The overall local control rates were 97%, 86%, 81%, and 76% at 6, 12, 18, and 24 months, respectively. Local control rates varied among the tumor types, and metastatic colorectal cancer showed significantly (P = .023) higher local control rates than those of the four other types. However, multivariate analysis indicated that the relative risk of local progression for a given tumor type was comparable to the risks for the four other types.
    Conclusion: : Tumor type per se did not significantly influence local control. (C) 2009 Elsevier Ireland Ltd. All rights reserved.

    DOI: 10.1016/j.ejrad.2009.01.026

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  • Incidence of and Risk Factors for Pneumothorax and Chest Tube Placement After CT Fluoroscopy-Guided Percutaneous Lung Biopsy: Retrospective Analysis of the Procedures Conducted Over a 9-Year Period

    Takao Hiraki, Hidefumi Mimura, Hideo Gobara, Kentaro Shibamoto, Daisaku Inoue, Yusuke Matsui, Susumu Kanazawa

    AMERICAN JOURNAL OF ROENTGENOLOGY194 ( 3 ) 809 - 814   2010年3月

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    記述言語:英語   出版者・発行元:AMER ROENTGEN RAY SOC  

    OBJECTIVE. The objective of our study was to retrospectively evaluate the incidence of and the risk factors for pneumothorax and chest tube placement after CT fluoroscopy-guided lung biopsy.
    MATERIALS AND METHODS. We analyzed 1,098 CT fluoroscopy-guided lung biopsies conducted with 20-gauge coaxial cutting needles for 1,155 lesions in 1,033 patients. Apart from evaluating the incidence of pneumothorax and chest tube placement, the independent risk factors for pneumothorax and chest tube placement for pneumothorax were determined using multivariate logistic regression analysis.
    RESULTS. The overall incidence of pneumothorax was 42.3% (464/1,098). Chest tube placement was required for 11.9% (55/464) of pneumothoraces (5.0% [55/1,098] of the total number of procedures). The significant independent risk factors for pneumothorax were no prior pulmonary surgery (p = 0.001), lesions in the lower lobe (p < 0.001), greater lesion depth (p < 0.001), and a needle trajectory angle of < 45 degrees (p = 0.014); those for chest tube placement for pneumothorax were pulmonary emphysema (p < 0.001) and greater lesion depth (p < 0.001).
    CONCLUSION. Pneumothorax frequently occurred and placement of a chest tube was occasionally required for pneumothorax after CT fluoroscopy-guided lung biopsy. To reduce the risk of pneumothorax necessitating chest tube placement, physicians should adopt the shortest needle path to the lesion.

    DOI: 10.2214/AJR.09.3224

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  • RFAの実際.

    金澤 右, 郷原英夫

    臨床画像26巻 ( 2号 ) 183 - 191   2010年

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  • 血管腫・血管奇形に対するinterventional radiology

    三村秀文, 藤原寛康, 平木隆夫, 郷原英夫, 芝本健太郎, 木股 敬裕, 尾﨑 敏文, 佐々木 了, 金澤 右

    岡山医学会雑誌122巻 ( 1号 ) 55 - 59   2010年

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  • Single Application of Radiofrequency Ablation of Small Lung Metastases with a 2-cm Expandable Electrode: Determination of Favorable Responders.

    Sakurai J, Hiraki T, Mimura H, Gobara H, Fujiwar H, Tajiri N, Sano Y, Kanazawa S

    J Vasc Interv Radiol21巻   231 - 236   2010年

  • Central Retinal and Posterior Ciliary Artery Occlusion After Intralesional Injection of Sclerosant to Glabellar Subcutaneous Hemangioma

    Toshihiko Matsuo, Hiroyasu Fujiwara, Hideo Gobara, Hidefumi Mimura, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY32 ( 2 ) 341 - 346   2009年3月

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    記述言語:英語   出版者・発行元:SPRINGER  

    The aim of this study is to describe vision loss caused by central retinal artery and posterior ciliary artery occlusion as a consequence of sclerotherapy with a polidocanol injection to a glabellar hemangioma. An 18-year-old man underwent direct injection with a 23-gauge needle of 1 mL of a polidocanol-carbon dioxide emulsion into the glabellar subcutaneous hemangioma under ultrasound visualization of the needle tip by radiologists. He developed lid swelling the next day, and 3 days later at referral, the visual acuity in the left eye was no light perception. Funduscopy revealed central retinal artery occlusion and fluorescein angiography disclosed no perfusion at all in the left fundus, indicating concurrent posterior ciliary artery occlusion. The patient also showed mydriasis, blepharoptosis, and total external ophthalmoplegia on the left side. Magnetic resonance imaging demonstrated the swollen medial rectus muscle. In a month, blepharoptosis and ophthalmoplegia resolved but the visual acuity remained no light perception. Sclerosing therapy for facial hemangioma may develop a severe complication such as permanent visual loss.

    DOI: 10.1007/s00270-008-9382-9

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  • Percutaneous radiofrequency ablation of lung cancer

    Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Yoshifumi Sano, Susumu Kanazawa

    The Lancet Oncology9 ( 7 ) 604 - 605   2008年7月

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)  

    DOI: 10.1016/S1470-2045(08)70159-1

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  • Measurement of pleural temperature during radiofrequency ablation of lung tumors to investigate its relationship to occurrence of pneumothorax or pleural effusion

    Nobuhisa Tajiri, Takao Hiraki, Hidefumi Mimura, Hideo Gobara, Takashi Mukai, Soichiro Hase, Hiroyasu Fujiwara, Toshihiro Iguchi, Jun Sakurai, Motoi Aoe, Yoshifumi Sano, Hiroshi Date, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY31 ( 3 ) 581 - 586   2008年5月

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    記述言語:英語   出版者・発行元:SPRINGER  

    The purpose of this study was to investigate the relationship between pleural temperature and pneumothorax or pleural effusion after radiofrequency (RF) ablation of lung tumors. The pleural temperature was measured immediately outside the lung surface nearest to the tumor with a fiber-type thermocouple during 25 ablation procedures for 34 tumors in 22 patients. The procedures were divided into two groups depending on the highest pleural temperature: P-group I and P-group II, with highest pleural temperatures of < 40 degrees C and >= 40 degrees C, respectively. The incidence of pneumothorax or pleural effusion was compared between the groups. Multiple variables were compared between the groups to determine the factors that affect the pleural temperature. The overall incidence of pneumothorax and pleural effusion was 56% (14/25) and 20% (5/25), respectively. Temperature data in five ablation procedures were excluded from the analyses because these were affected by the pneumothorax. P-group I and P-group II comprised 10 procedures and 10 procedures, respectively. The incidence of pleural effusion was significantly higher in P-group II (4/10) than in P-group I (0/10) (p = 0.043). However, the incidence of pneumothorax did not differ significantly (p = 0.50) between P-group I (4/10) and P-group II (5/10). Factors significantly affecting the pleural temperature were distance between the electrode and the pleura (p < 0.001) and length of the lung parenchyma between the electrode and the pleura (p < 0.001). We conclude that higher pleural temperature appeared to be associated with the occurrence of pleural effusion and not with that of pneumothorax.

    DOI: 10.1007/s00270-007-9283-3

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  • Repeat radiofrequency ablation for local progression of lung tumors: Does it have a role in local tumor control?

    Takao Hiraki, Hidefumi Mimura, Hideo Gobara, Yoshifumi Sano, Hiroyasu Fujiwara, Hiroshi Date, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY19 ( 5 ) 706 - 711   2008年5月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    PURPOSE: To retrospectively evaluate the role of repeat radiofrequency (RF) ablation for local progression of lung tumors in local tumor control.
    MATERIALS AND METHODS: From June 2001 to February 2007, the authors treated 797 lung tumors (primary lung cancer, n = 66; metastatic lung neoplasm, n = 731; mean tumor size, 1.7 cm) in 295 patients with RF ablation. After RF ablation, patients were followed-up with contrast-enhanced chest computed tomography at 1, 3, 6, 9, and 12 months and thereafter at 6-month intervals. Local progression was observed in 117 of the 797 lung tumors. Fifty repeat RF ablation sessions Were performed for 56 tumors (primary lung cancer, n = 9; metastatic lung neoplasm, n = 47; mean tumor size, 2.7 cm) in 46 patients (33 men, 13 women; mean age, 59.6 years). Repeat RF ablation was not performed for the remaining 61 locally progressing tumors because it was not presumed to provide survival benefit. For all 797 tumors, the overall primary and secondary technique effectiveness rates (TERs) after the first RF ablation were compared with each other. To determine the risk factors for local control with repeat RF ablation, multiple variables were analyzed. Next, local control with repeat RF ablation was evaluated for tumors with and tumors without risk factors.
    RESULTS: The overall secondary TERs were significantly higher than the overall primary TERs W <.00001). Tumor size of at least 2 cm at the first RF ablation W =.045) and contact with bronchi W =.045) or vessels W =.048) were risk factors for local control with repeat RF ablation. The secondary TERs after the first RF ablation were 94% at 1 year, 68% at 2 years, and 55% at 3 years for tumors without risk factors and 60% at 1 year and 40% at 2 years for tumors with at least one risk factor. Among the 50 repeat RF ablation sessions, pneurnothorax occurred in 13 sessions (26%), one of which necessitated chest tube placement; pleural effusion occurred in nine sessions (18%), all of which resolved spontaneously. Thermal injury of the brachial plexus occurred after one session.
    CONCLUSIONS: Repeat RF ablation improved the overall local control outcomes. In particular, it offered an opportunity to salvage tumors that had no risk factors but nevertheless progressed locally after the first RF ablation. Conversely, tumors with risk factors were not controlled sufficiently even after repeating the procedure.

    DOI: 10.1016/j.jvir.2007.12.441

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  • Preliminary retrospective investigation of FDG-PET/CT timing in follow-up of ablated lung tumor

    Fumiyo Higaki, Yoshihiro Okumura, Shuhei Sato, Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Shiro Akaki, Toshihide Tsuda, Susumu Kanazawa

    ANNALS OF NUCLEAR MEDICINE22 ( 3 ) 157 - 163   2008年4月

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    記述言語:英語   出版者・発行元:SPRINGER  

    Objective The aim of this study was to clarify the most appropriate follow-up initiation time point for positron emission tomography (PET)/computed tomography (CT) following radio frequency ablation (RFA) of lung tumors, and the cutoff values of maximum standard uptake value (SUVmax) to evaluate local tumor progression.
    Methods We enrolled 15 patients (8 men, median age 62 years) with 60 tumors, who were treated with RFA of lung tumors and underwent fluorodeoxyglucose (FDG)-PET/CT following RFA. Local tumor progression was assessed by periodic chest CT images prior to and following intravenous administration of a contrast medium. The SUVmax of three periods, namely, 03 months, 3-6 months, and 6-9 months after RFA, was evaluated. The appropriate time point for follow-up initiation and the cutoff value of SUVmax were determined using receiver-operating characteristic (ROC) analysis.
    Results The median follow-up period was 357 days. Of 60 tumors, 10 showed local progression. The area under the ROC curve (Az) for the 6-9 months (P = 0.044) was the largest and almost equal to that of the 3-6 months (P = 0.024). Az for the 0-3 months was the smallest and statistically insignificant (P = 0.705). The cutoff value of 1.5 of SUVmax at 3-9 months after RFA showed 77.8% sensitivity and 85.7-90.5% specificity.
    Conclusions The appropriate follow-up initiation time point is at least 3 months following RFA. Thus, SUVmax is a useful and reliable predictive indicator.

    DOI: 10.1007/s12149-007-0113-0

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  • Radiofrequency ablation of functioning lung metastases from parathyroid carcinoma

    Toshihiro Iguchi, Kotaro Yasui, Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Shuhei Sato, Hiroyasu Fujiwara, Ai Yano, Hiroyoshi Doihara, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY19 ( 3 ) 462 - 464   2008年3月

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE INC  

    DOI: 10.1016/j.jvir.2007.12.440

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  • A novel strategy for treatment of metastatic pulmonary tumors: radiofrequency ablation in conjunction with surgery. 国際誌

    Yoshifumi Sano, Susumu Kanazawa, Hidefumi Mimura, Hideo Gobara, Takao Hiraki, Hiroyasu Fujiwara, Masaomi Yamane, Shinichi Toyooka, Takahiro Oto, Hiroshi Date

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer3 ( 3 ) 283 - 8   2008年3月

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    記述言語:英語  

    INTRODUCTION: Local treatment that includes surgical resection of metastatic pulmonary tumors is controversial because of the biologic features and invasiveness of these tumors. We report our experience with a premeditated treatment involving combined computed tomography-guided radiofrequency ablation and surgical resection in three patients with metastatic pulmonary tumors. METHODS: Three patients underwent radiofrequency ablation in conjunction with surgical resection. The first was a 67-year-old man with pulmonary metastases of bronchial adenoid cystic carcinoma. We performed partial resection of five tumors in the right lung and ablated a tumor in the left lung. The second was a 66-year-old man with pulmonary metastases of renal cell carcinoma. He underwent radiofrequency ablation for three tumors in the right upper and middle lobes, and right lower lobectomy for tumors in that lobe. The third was a 55-year-old man with pulmonary metastases of high-grade sarcoma of the right thigh. We performed partial resection of five tumors in the left lung and ablated a tumor in the right lung. RESULTS: Two patients had metastatic lesions on both sides of the lung; we performed surgical resection on one side and radiofrequency ablation contralaterally to avoid bilateral thoracotomy. The third patient underwent surgical resection and radiofrequency ablation to avoid highly invasive right pneumonectomy. All patients survived for more than 1(1/2) years after combination therapy. CONCLUSIONS: Premeditated treatment involving a combination of radiofrequency ablation and surgical resection can be a useful option in patients with metastatic pulmonary tumors, improving curability and avoiding highly invasive procedures.

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  • Radiofrequency ablation of functioning lung metastases from parathyroid carcinoma

    Toshihiro Iguchi, Kotaro Yasui, Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Shuhei Sato, Hiroyasu Fujiwara, Ai Yano, Hiroyoshi Doihara, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY19 ( 3 ) 462 - 464   2008年3月

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    記述言語:英語   掲載種別:速報,短報,研究ノート等(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE INC  

    DOI: 10.1016/j.jvir.2007.12.440

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  • A novel strategy for treatment of metastatic pulmonary tumors: radiofrequency ablation in conjunction with surgery. 国際誌

    Yoshifumi Sano, Susumu Kanazawa, Hidefumi Mimura, Hideo Gobara, Takao Hiraki, Hiroyasu Fujiwara, Masaomi Yamane, Shinichi Toyooka, Takahiro Oto, Hiroshi Date

    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer3 ( 3 ) 283 - 8   2008年3月

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    記述言語:英語  

    INTRODUCTION: Local treatment that includes surgical resection of metastatic pulmonary tumors is controversial because of the biologic features and invasiveness of these tumors. We report our experience with a premeditated treatment involving combined computed tomography-guided radiofrequency ablation and surgical resection in three patients with metastatic pulmonary tumors. METHODS: Three patients underwent radiofrequency ablation in conjunction with surgical resection. The first was a 67-year-old man with pulmonary metastases of bronchial adenoid cystic carcinoma. We performed partial resection of five tumors in the right lung and ablated a tumor in the left lung. The second was a 66-year-old man with pulmonary metastases of renal cell carcinoma. He underwent radiofrequency ablation for three tumors in the right upper and middle lobes, and right lower lobectomy for tumors in that lobe. The third was a 55-year-old man with pulmonary metastases of high-grade sarcoma of the right thigh. We performed partial resection of five tumors in the left lung and ablated a tumor in the right lung. RESULTS: Two patients had metastatic lesions on both sides of the lung; we performed surgical resection on one side and radiofrequency ablation contralaterally to avoid bilateral thoracotomy. The third patient underwent surgical resection and radiofrequency ablation to avoid highly invasive right pneumonectomy. All patients survived for more than 1(1/2) years after combination therapy. CONCLUSIONS: Premeditated treatment involving a combination of radiofrequency ablation and surgical resection can be a useful option in patients with metastatic pulmonary tumors, improving curability and avoiding highly invasive procedures.

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  • Detection of EGFR gene mutations using the wash fluid of CT-guided biopsy needle in NSCLC patients

    Hiroki Otani, Shinichi Toyooka, Junichi Soh, Hiromasa Yamamoto, Hiroshi Suehisa, Naruyuki Kobayashi, Hideo Gobara, Hidefumi Mimura, Katsuyuki Kiura, Yoshifumi Sano, Susumu Kanazawa, Hiroshi Date

    Journal of Thoracic Oncology3 ( 5 ) 472 - 476   2008年

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    記述言語:英語   出版者・発行元:International Association for the Study of Lung Cancer  

    INTRODUCTION: In this study, we examined whether epidermal growth factor receptor (EGFR) mutations were detectable using a polymerase chain reaction-based assay and wash fluid of computed tomography (CT)-guided lung biopsy needles. METHODS: DNA was extracted from wash fluid of CT-guided biopsy needles of 53 lung tumors (as diagnosed according to the results of the CT-guided biopsies). EGFR mutations, specifically exon19 deletions and exon21 L858R mutations, were examined using a mutant-enriched polymerase chain reaction assay. We also examined the presence of EGFR mutations in 26 surgically resected tumor specimens and compared the results with those obtained for the corresponding wash fluid samples. RESULTS: The amount of DNA obtained for the wash fluid of the CT-guided biopsy needles ranged from 35 to 2360 ng. There were no significant differences in the amount of extracted DNA according to the tumor characteristics, including tumor size and the percentage of ground glass opacity. Thirty-four of the 53 lung tumor samples were histologically diagnosed as non-small cell lung cancer (NSCLC). Exon19 deletions and exon21 L858R mutations in EGFR were detected in 4 (12%) and 13 (38%) of 34 NSCLC cases, respectively. No EGFR mutations were found in the non-NSCLC cases. The EGFR mutation status in the wash fluid samples was consistent with those obtained for all 26 corresponding surgical specimens. CONCLUSION: Our results indicate that EGFR mutations can be detected using wash fluid of CT-guided biopsy needles. In this manner, the DNA genotype can be determined even in extremely small clinical specimens using highly sensitive assays. © 2008International Association for the Study of Lung Cancer.

    DOI: 10.1097/JTO.0b013e31816de2cd

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  • Percutaneous radiofrequency ablation for clinical stage Ⅰ non-small cell lung cancer: Results in nonsurgical candidates

    Hiraki T, Gobara H, Iishi T, Sano Y, Iguchi T, Fujiwara H, Tajiri N, Sakurai J, Date H, Mimura H, Kanazawa S

    J Thorac Cardiovasc Surg.134 ( 5 ) 1306 - 1312   2007年11月

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  • Percutaneous radiofrequency ablation for pulmonary metastases from colorectal cancer: Midterm results in 27 patients

    Takao Hiraki, Hideo Gobara, Tatsuhiko Iishi, Yoshifumi Sano, Toshihiro Iguchi, Hiroyasu Fujiwara, Nobuhisa Tajiri, Jun Sakurai, Hiroshi Date, Hidefumi Mimura, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY18 ( 10 ) 1264 - 1269   2007年10月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    PURPOSE: To retrospectively evaluate the midterm outcomes (eg, safety, local efficacy, and survival) after radiofrequency (RF) ablation for pulmonary metastases from colorectal cancer.
    MATERIALS AND METHODS: Twenty-seven patients (19 men and eight women; mean age, 61.6 years) with 49 pulmonary metastases (mean long axis diameter, 1.5 cm) from colorectal cancer underwent 41 percutaneous computed tomography (CT)-guided RF ablation sessions. Follow-up examinations were performed with CT by using contrast medium administration in all patients; positron emission tomography was performed in five patients. The safety of the procedure, local tumor control, and patient survival were evaluated. Multiple variables were analyzed to determine prognostic factors.
    RESULTS: Pneumothorax occurred after 20 of the 41 sessions (49%), three of which necessitated chest tube placement. A small pleural effusion was found after six of the 41 sessions (15%). No maj or hemorrhagic event was observed. None of the patients died due to the procedure. The median follow-up period was 20.1 months (range, 11.2-47.7 months). The primary and secondary technique effectiveness rates were 72% and 85%, respectively, at 1 year, 56% and 62% at 2 years, and 56% and 62% at 3 years. The overall survival rates after RF ablation were 96% at 1 year, 54% at 2 years, and 48% at 3 years. The presence of extrapulmortary metastasis was determined to be a prognostic factor (P =.001).
    CONCLUSIONS: The midterm outcomes of percutaneous RF ablation for colorectal pulmonary metastases appear promising. The presence of extrapulmonary metastasis had an adverse effect on survival after RF ablation.

    DOI: 10.1016/j.jvir.2007.06.027

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  • Nonfatal systemic air embolism complicating percutaneous CT-guided transthoracic needle biopsy - Four cases from a single institution

    Takao Hiraki, Hiroyasu Fujiwara, Jun Sakurai, Toshihiro Iguchi, Hideo Gobara, Nobuhisa Tajirl, Hidefumi Mimura, Susumu Kanazawa

    CHEST132 ( 2 ) 684 - 690   2007年8月

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    記述言語:英語   出版者・発行元:AMER COLL CHEST PHYSICIANS  

    Background: Systemic air embolism is recognized as a potentially fatal but extremely rare complication following percutaneous transthoracic needle biopsy. However, its incidence might be underestimated by missing systemic air in patients without cardiac or cerebral symptoms. Methods: This study was based on four cases (one man and three women; age range, 54 to 75 years) of systemic air embolism complicating CT scan-guided transthoracic needle biopsy, which were encountered among 1,010 procedures performed at our institution from April 1999 to December 2006. The target lesion was a lung tumor in three patients, and a mediastinal tumor in one patient. The procedure was performed percutaneously under CT scan-fluoroscopic guidance by using a coaxial biopsy needle system. Results: In all four patients, a specimen was successfully obtained from the lesions. During or immediately after the procedure, all patients experienced paroxysms of coughing. In three patients without cardiac or cerebral symptoms, the presence of systemic air was confirmed on postprocedural CT scan images; it was resolved without causing morbidity after the immediate therapy. The presence of systemic air was missed in one initially asymptomatic patient, resulting in a subsequent neurologic deficit. Conclusions: Systemic air embolism following CT scan-guided. transthoracic needle biopsy was encountered more frequently than would be expected. The considerable attention we gave to this complication enabled us to recognize it in patients without cardiac or cerebral symptoms. No sequelae were observed in the three patients in whom systemic air embolism was detected, and the therapy was initiated immediately, whereas missing systemic air led to cerebral embolism in one patient in our four cases.

    DOI: 10.1378/chest.06-3030

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  • Transhepatic approach for percutaneous computed-tomography-guided radiofrequency ablation of renal cell carcinoma

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Takashi Mukai, Soichiro Hase, Hiroyasu Fujiwara, Nobuhisa Tajiri, Jun Sakurai, Hidefumi Mimura, Takashi Saika, Hiromi Kumon, Susumu Kanazawa

    CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY30 ( 4 ) 765 - 769   2007年7月

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    記述言語:英語   出版者・発行元:SPRINGER  

    We performed percutaneously radiofrequency (RF) ablation of 5 renal cell carcinomas (mean diameter 26 +/- 15 mm) with computed-tomography (CT) fluoroscopic guidance using the transhepatic route. The RF electrode was successfully advanced into all tumors. RF ablation caused one minor complication (small asymptomatic perirenal hematoma); no major complications occurred. The follow-up contrast-enhanced CT images showed no local tumor progression of any tumors in a median period of 10 months (range 3-14 months). In conclusion, it seems that this transhepatic approach is safe and can be an alternative method for electrode insertion during RF ablation of selected renal tumors.

    DOI: 10.1007/s00270-007-9037-2

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  • Percutaneous radiofrequency ablation of lung tumors close to the heart or aorta: Evaluation of safety and effectiveness

    Toshihiro Iguchi, Takao Hiraki, Hideo Gobara, Hidefumi Mimura, Hiroyasu Fujiwara, Nobuhisa Tajiri, Jun Sakurai, Kotaro Yasui, Hiroshi Date, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY18 ( 6 ) 733 - 740   2007年6月

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    記述言語:英語   出版者・発行元:ELSEVIER SCIENCE INC  

    PURPOSE: The authors retrospectively evaluated the safety and effectiveness of percutaneous radiofrequency ablation of lung tumors close to the heart or aorta.
    MATERIALS AND METHODS: Forty-two tumors (mean diameter, 25 mm +/- 16; range, 5-73 mm) located less than 10 mm. from the heart or aorta were treated with radiofrequency ablation in 47 sessions. Lung tumors were classified into two groups according to their distance from the heart or aorta: group A (n = 27) comprised tumors at a distance of 1-9 mm; group B (n = 15) comprised contiguous tumors (distance, 0 mm). The safety and technique effectiveness of the procedure, defined as no evidence of local tumor progression, were evaluated.
    RESULTS: Radiofrequency ablation was feasible for all the 42 tumors. Procedural complications included asymptomatic pleural effusion (n = 5), small pneumothorax (n = 11), pneumothorax that necessitated chest tube placement (n = 4), and lung abscess (n = 1). No complications related to the specific tumor location, such as the accidental insertion of the electrode into the heart or aorta, pericardial effusion, arrhythmia, or cardiac infarction, occurred. The overall primary technique effectiveness rate was 75.8%, 45.9%, and 45.9% at 6, 12, and 24 months, respectively. This rate in group A (94.7%, 69.3%, and 69.3% at 6, 12, and 24 months, respectively) was significantly (P < .001) higher than that in group B (42.9% and 8.6% at 6 and 12 months, respectively).
    CONCLUSIONS: Radiofrequency ablation of lung tumors close to the heart or aorta was safely performed. The local control of tumors contiguous to the heart or aorta was considerably lower compared with the tumors that were close but not contiguous to these structures.

    DOI: 10.1016/j.jvir.2007.02.024

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  • Radiofrequency ablation followed by radiation therapy for large primary lung tumors

    Takashi Mukai, Hidefumi Mimura, Hideo Gobara, Mitsuhiro Takemoto, Kengo Himei, Takao Hiraki, Soichiro Hase, Hiroyasu Fujiwara, Toshihiro Iguchi, Nobuhisa Tajiri, Jun Sakurai, Kotaro Yasui, Yoshifumi Sano, Hiroshi Date, Susumu Kanazawa

    ACTA MEDICA OKAYAMA61 ( 3 ) 177 - 180   2007年6月

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    記述言語:英語   出版者・発行元:OKAYAMA UNIV MED SCHOOL  

    We report the clinical experience of radiofrequency ablation followed by radiation therapy for large primary lung tumors. Two patients with large primary lung tumors were treated with combined radiofrequency ablation and radiation therapy, and good local control was observed. Combined radiofrequency ablation and radiation therapy that involves minimally invasive techniques appears to be promising for the treatment of large lung tumors.

    DOI: 10.18926/AMO/32906

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  • Feasibility of percutaneous radiofrequency ablation for intrathoracic malignancies - A large single-center experience

    Yoshifumi Sano, Susumu Kanazawa, Hideo Gobara, Takashi Mukai, Takao Hiraki, Soichiro Hase, Shinichi Toyooka, Motoi Aoe, Hiroshi Date

    CANCER109 ( 7 ) 1397 - 1405   2007年4月

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    記述言語:英語   出版者・発行元:JOHN WILEY & SONS INC  

    BACKGROUND. Radiofrequency ablation (RFA) has become an accepted alternative for treating intrathoracic malignancies; however, the incidence and characteristics of peri- and postprocedural complications are not well described. The purpose of the study was to assess the safety and technical feasibility of percutaneous RFA in unresectable intrathoracic malignancies.
    METHODS. Percutaneous RFA was performed in patients with intrathoracic malignancies between June 2001 and December 2004. In total, 366 tumors were treated in 137 patients in 211 sessions. All patients were nonsurgical candidates or had refused surgery. Three hundred and thirty-six lesions were subjected to RFA for the treatment of metastases and 30 lesions for primary lung carcinoma.
    RESULTS. Although no procedural mortality occurred, 2 patients died during the course of the study because of intractable pneumothorax and massive hemoptysis (0.9%). The overall major complication rate was 17.1% (pneumothoraces requiring tube drainage in 25, pleuritis in 6, pleural effusion requiring tube drainage in 4, lung abscess in 1, and intrapulmonary hemorrhage with hemothorax in 1). Minor complications included pneumothoraces not requiring tube drainage in 108 sessions, pleural effusion without drainage in 34, hemosputum ill 9, nausea and/or vomiting in 3, subcutaneous emphysema in 3, cough in 2, skin burn in 2, atelectasis in 1, and subileus in 1. High fever and/or chest pain were seen in 33.8% and 39.3% of patients, respectively.
    CONCLUSIONS. With over 200 procedures, RFA appears to be a safe and minimally invasive option with negligible mortality and little morbidity in selected patients with unresectable intrathoracic malignancies.

    DOI: 10.1002/cncr.22541

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  • Assessment of mean transit time in the engrafted lung with 133Xe lung ventilation scintigraphy improves diagnosis of bronchiolitis obliterans syndrome in living-donor lobar lung transplant recipients

    Shinya T, Sato S, Kato K, Gobara H, Akaki S, Date H, Kanazawa S

    Ann Nucl Med.22   31 - 39   2007年

  • 各種悪性腫瘍に対するラジオ波焼灼療法

    金澤 右, 三村秀文, 郷原英夫, 生口俊浩, 藤原寛康

    映像情報Medical39 ( 6 ) 544 - 550   2007年

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  • Radiofrequency ablation of normal lungs after pulmonary artery embolization with use of degradable starch microspheres: Results in a porcine model

    Takao Hiraki, Hideo Gobara, Jun Sakurai, Hidefumi Mimura, Takashi Mukai, Soichiro Hase, Toshihiro Iguchi, Hiroyasu Fujiwara, Nobuhisa Tajiri, Hiroyuki Yanai, Tadashi Yoshino, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY17 ( 12 ) 1991 - 1998   2006年12月

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    記述言語:英語   出版者・発行元:LIPPINCOTT WILLIAMS & WILKINS  

    PURPOSE: The present study was performed to evaluate the effect of pulmonary artery embolization on radiofrequency (RF) ablation of normal porcine lungs.
    MATERIALS AND METHODS: RF ablation zones (n = 34) were created in the normal lungs of five domestic pigs (five zones in each of the first two pigs and eight zones in each of the remaining three pigs) with an expandable multitined electrode with use of bilateral thoracotomy. RF ablation was performed without pulmonary artery embolization (group 1, n = 8), immediately after embolization (group 2, n = 11),15 minutes after embolization (group 3, n = 7), and 30 minutes after embolization (group 4, n = 8) with degradable starch microspheres. Among them, 12 ablation zones were excluded from this study because they were considerably limited by the presence of the pleura or large bronchi. The remaining 22 zones were included (n = 7, n = 5, n = 4, and n = 6 in groups 1, 2, 3, and 4, respectively). Coagulation necrosis volumes in the ablation zones were measured and compared among the groups.
    RESULTS: Coagulation necrosis volumes were 0.9 +/- 0.5 cm(3), 2.1 +/- 0.4 cm(3), 2.1 +/- 1.0 cm(3), and 1.9 +/- 0.6 cm(3) in groups 1, 2, 3, and 4, respectively. Groups 2-4 showed significantly larger coagulation volumes than group 1 (P = .012, P = .023, and P = .010 in groups 2, 3, and 4, respectively).
    CONCLUSION: Pulmonary artery embolization contributed to larger volumes of coagulation necrosis after RF ablation of normal lungs.

    DOI: 10.1097/01.RVI.0000251152.12254.AC

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  • Pneumothorax, pleural effusion, and chest tube placement after radiofrequency ablation of lung tumors: Incidence and risk factors

    Takao Hiraki, Nobuhisa Tajiri, Hidefumi Mimura, Kotaro Yasui, Hideo Gobara, Takashi Mukai, Soichiro Hase, Hiroyasu Fujiwara, Toshihiro Iguchi, Yoshifumi Sano, Nobuyoshi Shimizu, Susumu Kanazawa

    RADIOLOGY241 ( 1 ) 275 - 283   2006年10月

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    記述言語:英語   出版者・発行元:RADIOLOGICAL SOC NORTH AMERICA  

    Purpose: To retrospectively evaluate the incidence of and risk factors for pneumothorax, pleural effusion, and chest tube placement for pneumothorax after radiofrequency (RF) ablation of lung tumors.
    Materials and Methods: Institutional review board approval was obtained, with waiver of informed consent. This retrospective study comprised 224 ablation sessions for 392 tumors in 142 patients (92 men, 50 women; mean age, 64.0 years). Multiple variables were analyzed by using the Student t test or the Mann-Whitney U test for numerical values and by using the X-2 test or the Fisher exact test for categorical values in order to assess risk factors for pneumothorax, pleural effusion, and chest tube placement for pneumothorax.
    Results: The incidence of pneumothorax, pleural effusion, and chest tube placement for pneumothorax was 52% (117 of 224 sessions), 19% (42 of 224 sessions), and 21% ( 24 of 117 sessions), respectively. For pneumothorax, risk factors included male sex (P=.030), no history of pulmonary surgery (P <.001), a greater number of tumors ablated (P <.001), involvement of the middle or lower lobe (P =.008), and increased length of the aerated lung traversed by the electrode (P =.014). For pleural effusion, risk factors included the use of a cluster electrode (P =.008), decreased distance to the nearest pleura (P =.040), and decreased length of the aerated lung traversed by the electrode (P =.019). For chest tube placement for pneumothorax, risk factors included no history of pulmonary surgery (P =.002), the use of a cluster electrode (P <.001), and involvement of the upper lobe (P <.001).
    Conclusion: Pneumothorax and pleural effusion can occur after RF ablation in patients with lung tumors, and chest tube placement for pneumothorax is sometimes required.

    DOI: 10.1148/radiol.2411051087

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  • Percutaneous radiofrequency ablation combined with previous bronchial arterial chemoembolization and followed by radiation therapy for pulmonary metastasis from hepatocellular carcinoma

    Takao Hiraki, Hideo Gobara, Mitsuhiro Takemoto, Hidefumi Mimura, Takashi Mukai, Kengo Himei, Soichiro Hase, Toshihiro Iguchi, Hiroyasu Fujiwara, Takahito Yagi, Noriaki Tanaka, Susumu Kanazawa

    JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY17 ( 7 ) 1189 - 1193   2006年7月

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    記述言語:英語   出版者・発行元:LIPPINCOTT WILLIAMS & WILKINS  

    A 56-year-old man had a lung metastasis from hepatocellular carcinoma 4.7 cm X 3.4 cm in size located directly adjacent to the pulmonary hilar vessels. The tumor was treated with radiofrequency ablation combined with earlier bronchial arterial chernoembolization and subsequent radiation therapy. A complete remission of the tumor has been observed for 6 months since completion of therapy. Considering that complete treatment of such an intermediate-sized tumor adjacent to the large vessels is usually difficult with radiofrequency ablation alone, this result suggests a possible role for combined therapy for pulmonary neoplasms.

    DOI: 10.1097/01.RVI.0000228370.09886.66

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  • Radiofrequency ablation of metastatic mediastinal lymph nodes during cooling and temperature monitoring of the tracheal mucosa to prevent thermal tracheal damage: Initial experience

    T Hiraki, K Yasui, H Mimura, H Gobara, T Mukai, S Hase, H Fujiwara, N Tajiri, Y Naomoto, T Yamatsuji, Y Shirakawa, S Asami, H Nakatsuka, M Hanazaki, K Morita, N Tanaka, S Kanazawa

    RADIOLOGY237 ( 3 ) 1068 - 1074   2006年1月

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    記述言語:英語   出版者・発行元:RADIOLOGICAL SOC NORTH AMERICA  

    Institutional review board approval and patient informed consent were obtained. Radiofrequency ablation in a total of 10 sessions was performed for each mediastinal lymph node metastasis from esophageal cancer that had a mean largest diameter of 2.2 cm +/- 0.6 (standard deviation) in seven male patients (mean age, 59 years). During ablation, cooling and temperature of the tracheal mucosa were monitored in the proper position in eight of the 10 sessions; in the other two sessions, monitoring was not done because of tracheal stenosis (perforation resulted), Three of the four lymph nodes that were 2.0 cm or smaller in largest diameter showed no evidence of local progression for at least 1 year since ablation; all three of the nodes greater than 2.0 cm in largest diameter progressed within 6 months. The 1-year survival rate was 60%; the median survival time was 13 months. Radiofrequency ablation may be effective for local control of small metastatic mediastinal lymph nodes, and cooling and temperature monitoring of the tracheal mucosa in the proper position may prevent thermal tracheal damage, (c) RSNA, 2005.

    DOI: 10.1148/radiol.2373050234

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  • 肺腫瘍のCTガイド下RFAによる治療

    安井光太郎, 金澤 右, 郷原英夫, 向井 敬, 平木隆夫, 長谷聡一郎, 藤原寛康, 田尻展久, 戸上 泉, 井上信浩, 守都常晴, 長谷川 明

    臨床放射線   2006年

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  • 腫瘍 ablation 総論

    金澤 右, 郷原英夫, 向井 敬, 平木隆夫, 田尻展久, 櫻井 淳

    臨床放射線51,11,194-205.   2006年

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  • 私の考えるレジデンシープログラム

    郷原英夫, 金澤 右

    臨床画像22,6,1771-1775.   2006年

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  • 健診で発見された肺犬糸状虫症の1例 本邦報告117例の集計

    櫻井 淳, 郷原英夫, 田尻展久, 安藤由智, 丸山修一郎, 横山伸二, 大林千穂, 金澤 右

    臨床放射線   2006年

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  • 肺癌に対するラジオ波焼灼療法-当院での経験をもとに-

    郷原英夫, 向井 敬, 三村秀文, 平木隆夫, 佐野由文, 伊達洋至, 金澤 右

    IVR会誌   2006年

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  • Magnetic Resonance imaging Features of Epidermoid Cyst of the Ovaries: Magnetic Resonance and Computed Tomography Findings

    Shinya T, Joja I, Hashimura S, Hayashi H, Gobara H, Kato K, Sato S, Akaki S, Kanazawa S

    J Comput Assist Tomogr   2006年

  • Effects of Radiofrequency Ablation on Individual Renal Function: Assessment by Technetium-99m Mercaptoacetyltriglycine Renal Scintigraphy

    Mukai T, Sato S, Iguchi T, Mimura H, Yasui K, Gobara H, Saika T, Nasu Y, Kumon H, Kanazawa S

    Acta Med. Okayama   2006年

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  • Sloughing of Intraductal Tumor Thrombus of Hepatocellular Carcinoma after Transcatheter Chemoembolization Causing Obstructive Jaundice and Acute Pancreatitis

    Hiraki T, Sakurai J, Gobara H, Kawamoto H, Mukai T, Hase S, Iguchi T, Fujiwara H, Tajiri N, Shiratori Y, Kanazawa S

    J Vasc Interv Radiol.   2006年

  • Transsternal Approach for Computed Tomography-guided Percutaneous Radiofrequency Ablation of a Solitary Lung Metastasis

    Iguchi T, Hiraki T, Gobara H, Mimura H, Mukai T, Hase S, Fujiwara H, Tajiri N, Kanazawa S

    J Vasc Interv Radiol.   2006年

  • 肺腫瘍のRFA

    安井光太郎, 金澤 右, 郷原英夫, 向井 敬, 平木隆夫, 長谷聡一郎, 藤原寛康, 戸上 泉, 井上信浩, 守都常晴, 長谷川 明

    臨床放射線   2006年

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  • 気管冷却下に施行した縦隔リンパ節転移に対するラジオ波焼灼療法

    平木隆夫, 安井光太郎, 三村秀文, 郷原英夫, 向井 敬, 長谷聡一郎, 藤原寛康, 田尻展久, 猶本良夫, 山辻知樹, 白川靖博, 浅海信也, 中塚秀輝, 花崎元彦, 森田 潔, 田中紀章, 金澤 右

    岡山医学会雑誌   2006年

  • 皮質骨転移の1例

    田尻展久, 郷原英夫, 加藤勝也, 赤木史郎, 長谷聡一郎, 金澤 右

    臨床放射線   2005年

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  • 胸部悪性腫瘍に対するラジオ波(RFA)およびマイクロ波(MCT)治療

    佐野由文, 伊達洋至, 向井 敬, 郷原英夫, 金澤 右

    外科治療   2005年

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  • 肺悪性腫瘍のラジオ波治療

    金澤 右, 三村秀文, 郷原英夫, 向井 敬, 平木隆夫, 長谷聡一郎, 藤原寛康, 田尻展久, 佐野由文, 清水信義, 藤原俊義, 田中紀章

    成人病と生活習慣病   2005年

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  • 多発性後腹膜神経節細胞腫(ganglioneuroma)の1例

    平木隆夫, 三村秀文, 柳井広之, 郷原英夫, 向井 敬, 長谷聡一郎, 藤原寛康, 金澤 右

    臨床放射線   2005年

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  • RFA・PEI

    郷原英夫, 金澤 右

    臨床画像   2005年

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  • 肺悪性腫瘍のラジオ波治療.

    金澤 右, 向井 敬, 三村秀文, 田頭周一, 藤原寛康, 平木隆夫, 郷原英夫, 佐野由文, 伊達洋至, 藤原俊義, 清水信義, 横山正尚, 安井光太郎, 生口俊浩, 兵頭 剛

    映像情報Medical   2004年

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  • 多房性嚢胞性腫瘤を示した胆嚢癌の1例.

    田尻展久, 郷原英夫, 佐藤卓也, 安藤由智, 高橋三奈, 横山伸二, 金澤 右, 平木祥夫

    臨床放射線   2004年

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  • 浸潤性発育を示し悪性腫瘍と鑑別困難であった腎血管腫の1例

    郷原英夫, 安藤由智, 佐藤卓也, 田尻展久, 長谷聡一郎, 村田 匡, 野田雅敏, 金澤 右 平木祥夫

    腹部画像診断アトラス〔IIIV〕   2003年

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  • 卵巣疾患の鑑別診断

    郷原英夫, 安藤由智, 田尻展久, 佐藤卓也, 平木祥夫

    画像診断23巻 3号 245-253   2003年

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  • エストロゲン産生を認めた転移性卵巣腫瘍の1例

    安藤由智, 郷原英夫, 佐藤卓也, 田尻展久, 長谷聡一郎, 金澤 右 平木祥夫

    腹部画像診断アトラス〔IIIV〕   2003年

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  • 猫ひっかき病の2例

    安藤由智, 郷原英夫, 佐藤卓也, 長谷聡一郎, 藤原寛康, 三村秀文, 金澤 右 平木祥夫

    臨床放射線   2002年

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  • 特異な形態を呈し蛋白漏出性胃腸症をきたした早期胃癌の1例

    郷原英夫, 佐藤卓也, 長谷聡一郎, 安藤由智, 伊野英男, 大谷 順, 藤原寛康, 金澤 右 平木祥夫

    腹部画像診断アトラス〔IIV〕   2002年

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  • 原発巣から連続性に門脈内腫瘍栓をきたした胃癌の1例

    長谷聡一郎, 郷原英夫, 佐藤卓也, 安藤由智, 伊野英男, 藤原寛康, 三村秀文, 平木祥夫

    臨床放射線   2002年

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  • 異所性に膵管癌が併存したintraductal papillary mucinous tumor of the pancreasの1例

    郷原英夫, 長谷聡一郎, 藤原寛康, 水戸川芳巳, 三村秀文, 平木祥夫

    腹部画像診断アトラス〔IV〕   2001年

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  • 腰椎硬膜外膿瘍のMRI

    郷原英夫, 藤原寛康, 長谷聡一郎, 児玉浩昭, 平木祥夫

    臨床放射線   2001年

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  • 膵管狭細型慢性膵炎の1例

    長谷聡一郎, 郷原英夫, 藤原寛康, 水戸川芳巳, 三村秀文, 金澤 右 平木祥夫

    腹部画像診断アトラス〔IV〕   2001年

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  • 肝十二指腸間膜に限局した腹部リンパ節結核の1例

    藤原寛康, 長谷聡一郎, 郷原英夫, 水戸川芳已, 小村まき, 平木祥夫

    臨床放射線   2000年

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  • 直腸癌に合併したBiliary Hamartomasの1例

    郷原英夫, 長谷聡一郎, 塩出 壮, 水戸川芳已, 三村秀文, 平木隆夫, 平木祥夫

    腹部画像診断アトラス〔V〕   2000年

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▼全件表示

講演・口頭発表等

  • CT透視ガイド下腎腫瘍生検の検討

    第3回 日本泌尿器癌局所療法研究会  2017年 

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  • 病院情報のシステムのITセキュリティリスク

    福山医療センター オープンカンファレンス  2017年 

     詳細を見る

  • 高度腎機能障害患者に発生した腎がんに対する凍結治療:多施設による後向き研究

    第3回 日本泌尿器癌局所療法研究会  2017年 

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  • PD後に生じたCHA仮性動脈瘤出血に対してバイアバーンを用いて治療した1例

    第23回 日本血管内治療学会総会  2017年 

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  • 著名な門脈圧亢進を来したArterioportal Fistulaに対して塞栓術を施行した1例

    第128回 日本医学放射線学会中国・四国地方会  2017年 

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  • 先天性門脈欠損症の1例

    第128回 日本医学放射線学会中国・四国地方会  2017年 

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  • 腎血管筋脂肪腫の治療中に腎動静脈奇形が発見された1例

    第128回 日本医学放射線学会中国・四国地方会  2017年 

     詳細を見る

  • PD後に生じたCHA仮性動脈瘤出血に対してバイアバーンを用いて治療した1例

    第31回 中国四国IVR研究会  2017年 

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  • 遠隔読影の可能性 -岡山大学における運用から-

    第53回 日本医学放射線学会秋季臨床大会 -第30回 電子情報研究会学術集会-  2017年 

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  • 腎癌に対する凍結治療 Up to date

    第53回 日本医学放射線学会秋季臨床大会  2017年 

     詳細を見る

  • 高度腎機能障害患者に発生した腎がんに対する凍結治療:多施設による後向き研究

    第18回 RFA・凍結療法研究会  2017年 

     詳細を見る

  • 腎生検・凍結療法後に腫瘍播種を生じ再凍結療法を施行した1例

    第129回 日本医学放射線学会中国・四国地方会  2017年 

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  • 膵癌肝転移破裂に対しTAE施行した1例

    第31回 中国四国IVR研究会  2017年 

     詳細を見る

  • TIPS後にステント破損を認めた1例

    第31回 中国四国IVR研究会  2017年 

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  • 腎動静脈奇形に対して流出静脈からのアプローチで良好に塞栓できた1例

    第129回 日本医学放射線学会中国・四国地方会  2017年 

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  • 腎生検後に遅発性出血を来した1例

    第129回 日本医学放射線学会中国・四国地方会  2017年 

     詳細を見る

  • Beyond Kidney: Imaging for Systemic Diseases Affecting the Kidney. Where the Kidney Meets the Others?

    RSNA 102h scientific assembly & annual meeting 2016  2016年 

     詳細を見る

  • 血管内平滑筋腫症に対し動脈塞栓術を施行した1例

    第127回 日本医学放射線学会中国・四国地方会  2016年 

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  • 前立腺癌治療

    第2回 日本泌尿器癌局所療法研究会  2016年 

     詳細を見る

  • 前腕静脈奇形に対して凍結療法を施行した1例

    第45回 日本IVR学会総会  2016年 

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  • VHL患者の腎癌に対するラジオ波焼灼療法

    第75回 日本医学放射線学会総会  2016年 

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  • 凍結治療予定の小径腎腫瘍への腎生検の評価

    第2回 日本泌尿器癌局所療法研究会  2016年 

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  • 小腎腫瘍に対するCT透視ガイド下生検の安全性、診断能、失敗因子の検討

    第45回 日本IVR学会総会  2016年 

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  • 腎洞側に突出する腎癌に対するCT透視下凍結療法の検討

    第45回 日本IVR学会総会  2016年 

     詳細を見る

  • 腎癌凍結療法による腎嚢胞の縮小について

    第45回 日本IVR学会総会  2016年 

     詳細を見る

  • DEB-TACE後のHCC及び正常肝実質に生じる病理学的変化に対する検討

    第45回 日本IVR学会総会  2016年 

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  • Balloon displacementが必要であった腎癌凍結治療の1例

    第126回 日本医学放射線学会中国・四国地方会  2016年 

     詳細を見る

  • 腹壁から逆行性にアプローチした小腸静脈瘤の1例

    第126回 日本医学放射線学会中国・四国地方会  2016年 

     詳細を見る

  • DWHを用いたCT予約枠改善の試み

    第126回 日本医学放射線学会中国・四国地方会  2016年 

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  • Niti-S大腸ステントが有用だった悪性下大静脈症候群の1例

    第126回 日本医学放射線学会中国・四国地方会  2016年 

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  • ラジオ波、凍結治療後の画像診断:各臓器における画像スペクトラム

    第52回 日本医学放射線学会秋季臨床大会  2016年 

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  • 横隔膜近傍の肺腫瘍に対するRFAの検討

    第17回 RFA・凍結療法研究会  2016年 

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  • 電子カルテにおける画像検査の同意書の現状と問題点

    第29回 電子情報研究会学術集会  2016年 

     詳細を見る

  • IVRにおける仮想透視画像の有用性

    第30回 中国四国IVR研究会  2016年 

     詳細を見る

  • 入院後に突然出血した腎腫瘍の1例

    第30回 中国四国IVR研究会  2016年 

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  • 悪性下大静脈症候群に対してNiti-S大腸用ステントを留置し、水分管理に難渋した1例

    第30回 中国四国IVR研究会  2016年 

     詳細を見る

  • 腎癌の凍結治療:どこまで治療できるか

    第4回 JSURT  2016年 

     詳細を見る

  • EVAR後のType Ⅰaエンドリークに対して、経カテーテル的コイル塞栓術を施行した1例

    第127回 日本医学放射線学会中国・四国地方会  2016年 

     詳細を見る

  • EVAR後のtype2 endoleak に対して直接穿刺で流入・流出路を塞栓した1例

    第127回 日本医学放射線学会中国・四国地方会  2016年 

     詳細を見る

  • FGF-23産生腫瘍の局在同定に全身静脈サンプリングが有用であった1例

    第125回 日本医学放射線学会中国・四国地方会  2015年 

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  • 肺腫瘍に対するラジオ波焼灼療法:本邦における前向き多施設共同研究(JIVROSG-0702)

    第74回 日本医学放射線学会総会  2015年 

     詳細を見る

  • Radiofrequeny electric current energy delivery to cryoprobe tract:influence on ablation result in ex vivo liver model

    第44回日本IVR学会総会  2015年 

     詳細を見る

  • Radiofrequency ablation of lung metastases from head and neck adenoid cystic carcinoma

    第44回日本IVR学会総会  2015年 

     詳細を見る

  • Electrode tract embolization to decrease a risk of pneumothorax accompanied with lung radiofrequency ablation

    第44回日本IVR学会総会  2015年 

     詳細を見る

  • フィラリア性乳び尿に対するリンパ管造影の1例

    第124回日本医学放射線学会中国・四国地方会  2015年 

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  • 肺AVMに対するコイル塞栓術後に脳梗塞を生じた1例

    第124回日本医学放射線学会中国・四国地方会  2015年 

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  • 腎がんに対してRFAと同時に生検を施行した症例の検討

    第124回日本医学放射線学会中国・四国地方会  2015年 

     詳細を見る

  • 凍結治療とMRI

    Advanced CT・MR 2015  2015年 

     詳細を見る

  • 当院における副鼻腔癌に対する動注化学療法の治療成績

    第29回 中国四国IVR研究会  2015年 

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  • 腎凍結療法後に後腹膜膿瘍を生じた一例

    第29回 中国四国IVR研究会  2015年 

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  • 転移性骨腫瘍との鑑別に苦慮したradiation-induced sarcomaの1例

    第124回日本医学放射線学会中国・四国地方会  2015年 

     詳細を見る

  • リンパ管造影にて乳びの漏出が軽快した傍椎体部リンパ腫の1例

    第124回日本医学放射線学会中国・四国地方会  2015年 

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  • VATSマーカー留置時に緊張性心襄気腫を生じた1例

    第29回 中国四国IVR研究会  2015年 

     詳細を見る

  • 腎癌のcryoablation

    第3回 JSURT 泌尿器画像診断・治療技術研究会  2015年 

     詳細を見る

  • 腹腔動脈合併尾側膵切除術(DP-CAR)術前の血流改変にVacular plugを使用した1例

    第29回 中国四国IVR研究会  2015年 

     詳細を見る

  • 腎RFAと同一のセッションで腎生検を施行した症例の検討

    第16回 RFA・凍結療法研究会  2015年 

     詳細を見る

  • 腎疾患に対するIVR

    第44回 断層映像研究会  2015年 

     詳細を見る

  • タブレット端末を用いた夜間,休日読影

    第28回 電子情報研究会学術集会  2015年 

     詳細を見る

  • Cryoablation of vascular malformations: a phase I clinical trial.

    第30回欧州心臓血管IVR会議  2015年 

     詳細を見る

  • センチネルリンパ節を対側腋窩または対側乳房に認めた乳癌の3例

    第55回 日本核医学会学術総会  2015年 

     詳細を見る

  • A case of solitary sacral bone metastasis from hepatocellular carcinoma successfully treated with percutanesou cryoablation.

    第2回 Asian Conference on Tumor Ablation  2015年 

     詳細を見る

  • CT guided percutaneous cryoablation for renal cell carcinoma: Experience in 114 biopsy-proven cases.

    第2回 Asian Conference on Tumor Ablation  2015年 

     詳細を見る

  • 腎凍結療法による腎嚢胞への影響について

    第16回 RFA・凍結療法研究会  2015年 

     詳細を見る

  • 膵全摘術後に生じた腹腔動脈仮性瘤に対してグラフトマスターを使用した1例

    第125回 日本医学放射線学会中国・四国地方会  2015年 

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  • 肝移植後にトリニアキシシャルシステムを使用してPSEを施行した2例

    第125回 日本医学放射線学会中国・四国地方会  2015年 

     詳細を見る

  • Imaging Characteristics of Tumors and Tumor-like Lesions of the Foot: common, Less common, Rare disease.

    Radiological Society of North America 2015  2015年 

     詳細を見る

  • 凍結治療の基本と実際

    熊本画像診断研究会  2015年 

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  • 腎洞側に突出する腎癌に対する凍結療法の検討

    第125回 日本医学放射線学会中国・四国地方会  2015年 

     詳細を見る

  • Retrograde renal ablation via the renal vein as a new treatment option for renovascular hypertension.

    第44回日本IVR学会総会  2015年 

     詳細を見る

  • 電子カルテシステムにおけるCT/MRIの造影剤の同意書の検討

    第32回中国四国医療情報学研究会  2014年 

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  • Amplatzer Vascular plugの初期使用経験

    第123回 日本医学放射線学会中国四国地方  2014年 

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  • IVCフィルター抜去困難例に対して改良型wire-loop techniqueにて回収しえた1例

    第123回 日本医学放射線学会中国四国地方  2014年 

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  • 非小細胞肺癌の治療後合併症および変化におけるCT,FDG-PETの像について

    第73回 日本医学放射線学会総会  2014年 

     詳細を見る

  • IVRの最前線:凍結療法とIVRセンター

    第73回 日本医学放射線学会総会  2014年 

     詳細を見る

  • 腎凍結治療後のMRI所見

    第73回 日本医学放射線学会総会  2014年 

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  • 腎癌凍結療法後のCT画像

    第73回 日本医学放射線学会総会  2014年 

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  • 食道癌の肺転移に対する経皮的ラジオ波凝固療法の検討

    第73回 日本医学放射線学会総会  2014年 

     詳細を見る

  • すりガラス肺がんに対する経皮的ラジオ波焼灼療法

    第73回 日本医学放射線学会総会  2014年 

     詳細を見る

  • マルチスライスCT 透視装置を用いたCT ガイド下肺ラジオ波焼灼術における術者被曝の検討

    第43回 日本IVR学会総会  2014年 

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  • 肺アスペルギローマにラジオ波焼灼療法が有用であった1例

    第43回 日本IVR学会総会  2014年 

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  • 腎癌凍結療法後のCT 画像 ~ 主に腫瘍の造影効果について~

    第43回 日本IVR学会総会  2014年 

     詳細を見る

  • 経葉間ルートで行った術前VATS マーカー留置の検討

    第43回 日本IVR学会総会  2014年 

     詳細を見る

  • Morbidity&Mortality

    第43回 日本IVR学会  2014年 

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  • 内頸静脈穿刺にて留置したCV ポートカテーテル破損のリスク因子に対する検討

    第43回 日本IVR学会総会  2014年 

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  • 当院における異所性静脈瘤に対するIVR の検討

    第43回 日本IVR学会総会  2014年 

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  • 切除可能な大腸癌肺転移に対する経皮的ラジオ波凝固療法:第2相臨床試験(SURF study):症例登録完了報告

    第15回RFA・凍結療法研究会  2014年 

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  • Stage G4以上の慢性腎臓病に合併した腎癌に対する凍結治療

    第15回RFA・凍結療法研究会  2014年 

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  • 食道静脈瘤破裂を契機に発見された真性多血症の1例

    第28回日本腹部放射線学会  2014年 

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  • 若年成人発症の腎low-grade fibromyxoid sarcomaの1例

    第28回日本腹部放射線学会  2014年 

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  • レポート端末から電子カルテ端末への患者IDの受け渡しシステムの導入

    第27回電子情報研究会学術集会  2014年 

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  • A case of hepatic intracystic oraganizing hematoma mimicking billary cystadenocarcinoma in a polycystic liver diaease patient

    The 15th Asian Oceanian Congress of Radiology (AOCR2014)  2014年 

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  • Results of preoperative localizations of 200 small pulmonary lesions with a short hook wire and suture system

    The 15th Asian Oceanian Congress of Radiology (AOCR2014)  2014年 

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  • 電子カルテシステムにおけるCT/MRIの造影剤の同意書の検討

    第32回中国四国医療情報学研究会  2014年 

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  • 類骨骨種と鑑別が必要であった大腿骨頚部線維性骨異形成の1例

    第25回日本骨軟部放射線研究会  2014年 

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  • 類骨骨種と鑑別が必要であった大腿骨頚部線維性骨異形成の1例

    第25回日本骨軟部放射線研究会  2014年 

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  • 肺がんに対する画像ガイド下アブレーション治療

    第73回 日本医学放射線学会総会  2014年 

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  • 肺RFAにおける電極針展開径が局所制御に及ぼす影響についての検討

    第28回 中国四国IVR研究会  2014年 

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  • Cryoablation of renal cell carcinoma .

    第41回日本低温医学会総会  2014年 

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  • Stage G4以上の慢性腎臓病患者に合併した腎癌に対する凍結治療

    第28回 中国四国IVR研究会  2014年 

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  • 肺ラジオ波療法における穿刺経路塞栓の経験

    第28回 中国四国IVR研究会  2014年 

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  • 肺ラジオ波焼灼療法後の高度炎症:前向き試験における頻度と危険因子の検討

    第42回 日本IVR学会総会  2013年 

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  • 肺動静脈瘻の塞栓術後のaneurysmal sacの縮小率と再灌流の検討

    第72回 日本医学放射線学会総会  2013年 

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  • 肺ラジオ波焼灼療法後の高度炎症:前向き試験における頻度と危険因子の検討

    第72回 日本医学放射線学会総会  2013年 

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  • VHL関連腎癌に対するCTガイド下ラジオ波焼灼療法

    第72回 日本医学放射線学会総会  2013年 

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  • 良性胆管狭窄に対するチューブステント留置の長期成績

    第72回 日本医学放射線学会総会  2013年 

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  • 腎癌に対する凍結療法::初期経験の報告

    第72回 日本医学放射線学会総会  2013年 

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  • 類骨骨腫に対するラジオ波治療後のMRI 像の検討- 焼灼域の評価における有用性

    第42回 日本IVR学会総会  2013年 

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  • 腎癌の凍結療法-IVRセンター開設のご案内とともに-

    第62回 岡山画像診断センター病診連携勉強会  2013年 

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  • 経肩甲骨的に肺ラジオ波焼灼療法を施行した8例の検討

    第42回 日本IVR学会総会  2013年 

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  • 腎癌に対する凍結療法:初期経験の報告

    第42回 日本IVR学会総会  2013年 

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  • 腎凍結療法後の神経障害によると思われる疼痛

    第42回 日本IVR学会総会  2013年 

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  • 当院で経験した内頚静脈穿刺にて留置したシリコン性CV カテーテル破損14 例の検討

    第42回 日本IVR学会総会  2013年 

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  • 肝嚢胞性病変の1例

    第115回 肝胆膵研究会  2013年 

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  • 喀血を契機に発見された多発気管支動脈瘤に対して塞栓術を施行した一例

    第42回 日本IVR学会総会  2013年 

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  • Dual energy CT を用いた肺RFA のCT 画像評価:肺血流及び腫瘍成分の変化について

    第42回 日本IVR学会総会  2013年 

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  • 肝癌の孤立性仙骨転移に対して凍結治療を行った1例

    第121回 日本医学放射線学会 中国・四国地方会  2013年 

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  • 嚢胞硬化術によって肝容積減少を図ったADPCKの4例

    第120回 日本医学放射線学会中国・四国地方会  2013年 

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  • 腎癌に対する腎凍結療法:初期経験の報告

    第120回 日本医学放射線学会中国・四国地方会  2013年 

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  • PpPD術後に生じた総肝動脈仮性瘤に対してグラフトマスターを用いて治療した一例

    第120回 日本医学放射線学会中国・四国地方会  2013年 

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  • 各種がんに対するIVR治療

    岡山大学病院IVRセンター市民公開講座  2013年 

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  • F-18 FDG PET/CTが診断に有用であったRosai-Dorfman病の一例

    第26回 臨床核医学研究会  2013年 

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  • 両側巨大副腎myelolipomaの1例

    第27回 日本腹部放射線研究会  2013年 

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  • 前立腺肉腫の2例

    第27回 日本腹部放射線研究会  2013年 

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  • 胸部異常陰影の1例

    第34回岡山胸部画像病理カンファレンス  2013年 

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  • 肺癌の孤立性胸壁転移に対して凍結療法を施行した1例

    第14回 RFA研究会  2013年 

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  • 腎癌に対する腎凍結療法:初期経験の報告

    第14回 RFA研究会  2013年 

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  • T1b腎がんに対する凍結療法

    第121回 日本医学放射線学会 中国・四国地方会  2013年 

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  • 肺アスペルギローマにラジオ波焼灼療法が有用であった1例

    第121回 日本医学放射線学会 中国・四国地方会  2013年 

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  • F-18FDG PET/CTが診断に有用であったRosai-Dorfman病の2例

    第53回日本核医学会学術総会  2013年 

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  • 当院におけるクライオサージェリー現況と展望

    第51回 広島IVR研究会  2013年 

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  • MRIとSPECT-CTが診断に有用であったpure struma ovariiの一例

    第119回 日本医学放射線学会中国・四国地方会  2012年 

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  • Risk Factors for Systemic Air Embolism as a Complication of Percutaneous CT-guided Lung Biopsy: Multicentre Case-Control Study in Japan

    RSNA 98th scientific assembly & annual meeting 2012  2012年 

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  • 軟骨性腫瘍の良悪性鑑別におけるTc-99mDMSA(V)シンチグラフィの有用性に関する検討

    第52回 日本核医学会学術集会  2012年 

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  • Triaxial systemを使用して塞栓したtype II endoleakの1例

    第119回 日本医学放射線学会中国・四国地方会  2012年 

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  • 肝嚢胞性腫瘍との鑑別を要した肝嚢胞内出血の1例

    第119回 日本医学放射線学会中国・四国地方会  2012年 

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  • 肺RFA後の再発診断にDual energy CTによる成分分析が有用であった一例

    第119回 日本医学放射線学会中国・四国地方会  2012年 

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  • 腎凍結療法による神経障害と思われる疼痛をきたした10例

    第119回 日本医学放射線学会中国・四国地方会  2012年 

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  • 腎RFA直後の腎生検の有用性について

    第26回 日本IVR学会中国四国地方会  2012年 

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  • 腎腫瘍に対するラジオ波焼灼療法後の画像所見:典型例と非典型例

    第71回 日本医学放射線学会総会  2012年 

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  • Diagnostic lmaging and Radiofrequency Ablation of Renal ce11 Carcinoma

    The Myanmar Health Research congress (2011)  2012年 

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  • Diagnostic lmaging and Radiofrequency Ablation of Renal ce11 Carcinoma

    The Myanmar Health Research congress (2011)  2012年 

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  • Risk factors for systemic air embolism complicating percutaneous CT-guided lung biopsy: Multicenter casecontrol study in Japan

    APCCVIR 2012 JSIR & ISIR  2012年 

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  • Predictors of renal function after percutaneous radiofrequency ablation of renal tumor

    APCCVIR 2012 JSIR & ISIR  2012年 

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  • Association between sac shrinkage and recanalization after transcatheter coil embolization of pulmonary arteriovenous malformation

    APCCVIR 2012 JSIR & ISIR  2012年 

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  • 肺ラジオ波焼灼療法後のF-18 FDG集積に関する検討

    第71回 日本医学放射線学会総会  2012年 

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  • 小腸出血に対し緊急でバルーン閉塞下逆行性経静脈的塞栓術を施行した1例

    第118回 日本医学放射線学会中国・四国地方会  2012年 

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  • 経皮経肝的に塞栓を施行した肝仮性動脈瘤の1例

    第118回 日本医学放射線学会中国・四国地方会  2012年 

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  • イレウスにて発症した心嚢内ヘルニアの一例

    第118回 日本医学放射線学会中国・四国地方会  2012年 

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  • 子宮漿膜下に巨大腫瘤を形成した低悪性度子宮内膜間質肉腫の1例

    第26回 日本腹部放射線研究会  2012年 

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  • Desmoplastic small round cell tumorの1例

    第26回 日本腹部放射線研究会  2012年 

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  • 軟骨性腫瘍におけるTc-99m DMSA(Ⅴ)シンチグラフィの有用性の検討

    第47回 日本核医学会中国・四国地方会  2012年 

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  • 肩甲骨経由でCTガイド下穿刺を施行した6例

    第118回 日本医学放射線学会中国・四国地方会  2012年 

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  • 非小細胞肺癌におけるF-18 FDG PET/CTの有用性-転移性リンパ節と胸膜浸潤の診断に関して-

    第52回 日本核医学会学術集会  2012年 

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  • Bigplane angio装置を使用したTIPSの2例

    第26回 日本IVR学会中国四国地方会  2012年 

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  • 腎癌に対する経皮的ラジオ波焼却療法後に穿刺経路播種をきたした1例

    第26回 日本IVR学会中国四国地方会  2012年 

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  • "What happens?" Imaging spectrum after radiofrequency ablation of renal cell carcinoma: typical and atypical presentation

    Cardiovascular and Interventional Radiological Society of Europe 2011(CIRSE)  2011年 

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  • 肺ラジオ波焼灼療法後の高度炎症反応発生のリスクファクター

    第70回 日本医学放射線学会総会  2011年 

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  • change in renal function after percutaneous radiofrequency ablation of renal tumor:Analyses of risk factors

    2011 SIR Annual Scientific Meeting  2011年 

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  • EmbozeneTMによる動脈塞栓術が著効した仙骨巨細胞腫の1例

    第22回 骨軟部放射線研究会  2011年 

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  • 臨床病期Ⅰ期非小細胞肺癌に対する経皮的ラジオ波焼灼療法:50例での成績

    第70回 日本医学放射線学会総会  2011年 

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  • 悪性肺腫瘍に対する経皮的ラジオ波凝固療法についての第Ⅰ/Ⅱ相および第Ⅱ相臨床試験

    第40回 日本IVR学会総会  2011年 

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  • 軟部腫瘍の良悪性鑑別におけるTl-201腫瘍シンチグラフィの有用性

    第70回 日本医学放射線学会総会  2011年 

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  • 膵転移を来たした肝solitary fi brous tumor

    第25回 日本腹部放射線研究会  2011年 

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  • 軟部腫瘍の良悪性鑑別におけるTl-201シンチグラフィの有用性

    第46回 日本核医学会中国・四国地方会  2011年 

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  • 多発結節性脂肪肝の1例

    第116回 日本医学放射線学会中国・四国地方会  2011年 

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  • 肺RFA.治療の現況と画像評価法.

    第40回 日本IVR学会総会  2011年 

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  • 同時性バルーン閉鎖下塞栓術(DBOE)にて止血しえた十二指腸静脈瘤破裂の一例

    第117回 日本医学放射線学会中国・四国地方会  2011年 

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  • 肝動注リザーバー留置時の血流改変により肝梗塞を来した2例

    第117回 日本医学放射線学会中国・四国地方会  2011年 

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  • 肺RFAによる横隔神経麻痺の検討

    第12回 RFA談話会  2011年 

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  • 肝RFA後に広範な肉芽組織を形成した1例

    第115回 日本医学放射線学会中国・四国地方会  2010年 

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  • 芝刈り中、突然の後頚部痛・四肢麻痺をきたした特発性脊髄硬膜外血腫の1例

    第114回 日本医学放射線学会中国・四国地方会  2010年 

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  • FDG集積を示した上行結腸由来の神経鞘腫

    第24回 腹部放射線研究会  2010年 

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  • 膵粘液性嚢胞性腫瘍から発生した退形成性膵癌の1例

    第24回 腹部放射線研究会  2010年 

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  • 腎原発の骨外性ユーイング肉腫の1例

    第24回 腹部放射線研究会  2010年 

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  • 肺ラジオ波焼灼療法後のFDG-PET/CTの評価 -3ヶ月後と6ヶ月後の比較-

    第114回 日本医学放射線学会中国・四国地方会  2010年 

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  • 肺生検後に生じた心嚢気腫の一例

    第114回 日本医学放射線学会中国・四国地方会  2010年 

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  • 肺RFA後に呼吸停止をきたした1例

    第114回 日本医学放射線学会中国・四国地方会  2010年 

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  • FDG集積を示した横行結腸由来の神経鞘腫

    PETサマーセミナー2010 in 岡山  2010年 

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  • PET-CTが有用であった膵粘液性嚢胞性腫瘍から発生した退形成性膵癌の1例

    PETサマーセミナー2010 in 岡山  2010年 

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  • 肺ラジオ波焼灼療法後のFDG-PET/CTでの評価―3ヶ月後と6ヶ月後の評価―

    PETサマーセミナー2010 in 岡山  2010年 

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  • 18F-FDGの高集積を認めた低分化型肝細胞癌の1例

    PETサマーセミナー2010 in 岡山  2010年 

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  • EmbozeneTM による動脈塞栓術が著効した仙骨巨細胞腫の1例

    第24回 日本IVR学会中国四国地方会  2010年 

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  • EmbozeneTM embolization 後の平滑筋肉腫肝転移1切除例

    第24回 日本IVR学会中国四国地方会  2010年 

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  • 肝動注リザーバ留置後に形成した腹腔動脈瘤に対しコイル塞栓術を施行した1例

    第24回 日本IVR学会中国四国地方会  2010年 

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  • 多発HCC病変に対しミリプラチンを使用し重篤な副作用をおこした1例

    第24回 日本IVR学会中国四国地方会  2010年 

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  • 当院における生体肝移植後肝静脈拡張術

    第24回 日本IVR学会中国四国地方会  2010年 

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  • 肺RFA後に横隔膜ヘルニアを生じた1例

    第24回 日本IVR学会中国四国地方会  2010年 

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  • 多施設調査の結果速報

    第11回 RFA談話会  2010年 

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  • Myxoinflammatory fibroblastic sarcomaの1例

    第115回 日本医学放射線学会中国・四国地方会  2010年 

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  • Risk Factors for Severe Inflammatory Reaction after Percutaneous Radiofrequency Ablation of Lung Tumor.

    RSNA 96nd scientific assembly & annual meeting 2010  2010年 

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  • 良性嚢胞性骨腫瘍の画像診断―FEGNOMASHICは正しいか―

    第46回 日本医学放射線学会秋季臨床大会  2010年 

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  • 腎RFA後に腎盂内血腫をきたした一例

    第11回 RFA談話会  2010年 

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  • 当院における肺腫瘍に対する人口気胸下RFAの検討

    第39回 日本IVR学会総会  2010年 

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  • 腎RFAにてRCCを治療し糖尿病が改善した1例

    第29回 日本画像医学会  2010年 

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  • 肺ラジオ波焼灼術後のpneumatocele形成

    第69回 日本医学放射線学会総会  2010年 

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  • 類骨骨腫に対するラジオ波焼灼療法・当院における初期経験

    第69回 日本医学放射線学会総会  2010年 

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  • Percutaneous CT-guided radiofrequency ablation for renal cell carcinoma in von Hippel-Lindau disease

    European Congress of Radiology (ECR) 2010  2010年 

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  • Pneumatocele formation after radiofrequency ablation of lung tumor

    European Congress of Radiology (ECR) 2010  2010年 

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  • 肝細胞癌肺転移に対するラジオ波焼灼療法:多施設共同研究の結果

    第39回 日本IVR学会総会  2010年 

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  • 類骨骨腫に対するラジオ波焼灼療法

    第39回 日本IVR学会総会  2010年 

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  • 緩和医療とIVR~疼痛緩和について~

    第39回 日本IVR学会総会  2010年 

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  • 肝細胞癌肺転移に対するラジオ波焼灼療法:日本における多施設共同研究の結果

    第69回 日本医学放射線学会総会  2010年 

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  • CTガイド下のIVRの実際

    第39回 日本IVR学会総会  2010年 

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  • 腎RFA時の隣接臓器への熱損傷予防策についての検討

    第39回 日本IVR学会総会  2010年 

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  • 縦隔腫瘍の形態を呈して診断に苦慮した結核症の1例

    第22回 胸部放射線研究会  2008年 

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  • 生体肝移植後腹膜PTLD(Posttransplantation Lymphoprolifrerative Disorders)の一例

    第22回腹部放射線研究会  2008年 

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  • Thermal nerve injury after percutaneous radiofrecuensy ablation for lung tumor

    SIR 2008 annual meeting  2008年 

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  • Percutaneous CT-guided transthoracic needle biopsy of lung lesions with focul pure glound-glass opacity

    SIR 2008 annual meeting  2008年 

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  • 肺RFA後のtumor seeding

    第110回日本医学放射線学会中国・四国地方会  2008年 

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  • HIV陽性者に発症し、自然消褪した肺MAL Tomaの一例

    第110回日本医学放射線学会中国・四国地方会  2008年 

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  • 縦隔腫瘤の一例

    第25回 岡山胸部画像病理カンファレンス  2008年 

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  • 肺癌RFA後の再発におけるPET/CTの診断時期の検討

    第22回 日本IVR学会中国四国地方会  2008年 

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  • 結節生硬化症に伴う腎血管筋脂肪腫に対してエタノールによる腎動脈塞栓術後に肺水腫うぃお来した一例

    第22回 日本IVR学会中国四国地方会  2008年 

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  • 動脈塞栓術を施行した外傷性持続勃起症の一例

    第22回 日本IVR学会中国四国地方会  2008年 

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  • 大腿骨頭置換術による外腸骨静脈損傷をIVRで治療した一例

    第22回 日本IVR学会中国四国地方会  2008年 

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  • 末梢早期肺癌に対するラジオ波焼灼療法

    第49回 日本肺癌学会総会  2008年 

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  • 大腿骨頭置換術による外腸骨静脈損傷をIVRで治療した一例

    第18回 救急放射線研究会  2008年 

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  • 肺野に広範な間質性病変を主体としたびまん性陰影を認め、肺腺癌と好酸球性肺炎を合併し、多臓器病変を伴ったlgG4関連疾患の1例

    第22回 胸部放射線研究会  2008年 

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  • 胆嚢転移を呈した腎癌の2例

    第111回 日本医学放射線学会中国・四国地方会  2008年 

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  • PET/CTによる肺癌RFA後の再発診断の至適時期の検討

    第49回 日本肺癌学会総会  2008年 

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  • CT imaging findings after radiofrequency ablation for lung tumors; Morphological features of the tumors with and without local progression

    RSNA 93rd scientific assembly & annual meeting 2007  2007年 

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  • Percutaneous CT-guided radiofrequency ablation for metastatic lung tumor from hepatocellular carcinoma

    2007 SIR annual Scientific Meeting  2007年 

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  • Postablation Syndrome after Radiofrequency Ablation for Lung Tumors: Incidence and Risk Factors of Fever.

    2007 SIR annual Scientific Meeting  2007年 

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  • Desmoid-type fibromatosesに対するT1-201シンチグラフィの検討

    第66回 日本医学放射線学会学術集会  2007年 

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  • 肺腫瘍に対する肺ラジオ波焼灼術後のPostablation syndromeについて

    第66回 日本医学放射線学会学術集会  2007年 

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  • 2cm展開針を用いた肺ラジオ波焼灼術:1部位焼灼における局所制御率および再発危険因子の検討

    第66回 日本医学放射線学会学術集会  2007年 

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  • 術後肺癌の肺内再発に対するラジオ波焼灼療法の治療成績の検討

    第66回 日本医学放射線学会学術集会  2007年 

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  • 肝静脈再建を行った右葉graft生体移植後のCT

    第66回 日本医学放射線学会学術集会  2007年 

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  • 経肝的に施行したRCCに対するRFAの検討

    第66回 日本医学放射線学会学術集会  2007年 

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  • 肺腫瘍に対するラジオ波焼灼療法(RFA)後に神経損傷を来した2例

    第36回 日本IVR学会総会  2007年 

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  • 肺腫瘍に対するRFA

    第36回 日本IVR学会総会  2007年 

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  • 腎腫瘍に対するラジオ波焼灼療法-岡山大学における中期成績-

    第36回 日本IVR学会総会  2007年 

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  • Focal GGO病変に対するCTガイド下肺生検についての検討

    第36回 日本IVR学会総会  2007年 

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  • 十二指腸静脈瘤に対してIVRが有効であった3例

    第36回 日本IVR学会総会  2007年 

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  • 肺腫瘍のラジオ波焼灼療法後の局所再発における危険因子の検討:342個の腫瘍による評価

    第36回 日本IVR学会総会  2007年 

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  • VHL患者に対するCTガイド下腎RFA

    第36回 日本IVR学会総会  2007年 

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  • 類骨骨腫に対してRFAを施行した3例

    第8回 RFA談話会  2007年 

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  • CT上 pure GGO を呈した卵巣癌肺転移の一例

    第108回 日本医学放射線学会中国・四国地方会  2007年 

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  • 非典型的な画像を示し膵頭部腫瘍と鑑別が困難であったparagangliomaの一例

    第21回 腹部放射線研究会  2007年 

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  • 骨盤内肉腫様の所見を呈し、診断困難であった巨大血栓化静脈瘤の一例

    第21回 腹部放射線研究会  2007年 

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  • 類骨骨腫に対してRFAを施行した3例

    第21回 日本IVR学会中国・四国地方会  2007年 

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  • 生食注入下での肺RFA:ブタ正常肺での実験

    第21回 日本IVR学会中国・四国地方会  2007年 

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  • NOMIの4例

    第21回 日本IVR学会中国・四国地方会  2007年 

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  • 肺ラジオ波焼灼療法後に肺仮性動脈瘤を認めた一例

    第21回 日本IVR学会中国・四国地方会  2007年 

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  • Peribiliary cyst による胆管狭窄に対して嚢胞硬化術が有用であった1例

    第21回 日本IVR学会中国・四国地方会  2007年 

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  • 肝性脳症に対し脾静脈塞栓術が奏功した一例

    第21回 日本IVR学会中国・四国地方会  2007年 

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  • 多発性嚢胞腎に対して無水エタノールを用いて腎動脈塞栓術を施行した1例

    第21回 日本IVR学会中国・四国地方会  2007年 

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  • 肺腫瘍の良悪性診断における F-18 FDG PET/CT と MRI (DWIBS, T2WI) の比較

    第47回 日本肺癌学会総会  2006年 

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  • RFA後の肺結節性病変におけるFDG-PET/CTの診断能について

    第47回 日本肺癌学会総会  2006年 

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  • DSMを用いた肺動脈塞栓後の肺ラジオ波焼灼療法:ブタの正常肺を用いての検討

    第47回 日本肺癌学会総会  2006年 

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  • 心臓・大動脈に近接する肺腫瘍に対するラジオ波凝固療法の検討

    第47回 日本肺癌学会総会  2006年 

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  • Pneumothorax, pleural effusion, and chest tube placement after radeiofrequency ablation of lung tumors: incidence and risk factors

    RSNA 92nd scientific assembly & annual meeting 2006  2006年 

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  • CT-guided radiofrequency ablation for Stage I lung cancer; two center study

    2006 SIR 31st Annual Scientific Meeting  2006年 

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  • 原発性肺癌に対する肺ラジオ波焼灼療法(RFA)の中期治療成績-2施設共同研究-

    第65回 日本医学放射線学会学術集会  2006年 

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  • 肺ラジオ波焼灼療法における胸膜温度測定

    第65回 日本医学放射線学会学術集会  2006年 

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  • 多施設共同による腎癌肺転移に対する経皮的ラジオ波凝固療法の検討

    第65回 日本医学放射線学会学術集会  2006年 

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  • 生体部分肝移植における術前脾動脈塞栓術の有用性の検討

    第35回 日本IVR学会総会  2006年 

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  • 肺ラジオ波焼灼療法後に発生した胸膜炎症例の検討

    第35回 日本IVR学会総会  2006年 

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  • 肺腫瘍に対する経皮的ラジオ波焼灼療法の中期治療成績

    第65回 日本医学放射線学会学術集会  2006年 

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  • 静脈奇形に対する硬化療法

    第65回 日本医学放射線学会学術集会  2006年 

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  • 肺ラジオ波焼灼療術における胸膜温度測定

    第35回 日本IVR学会総会  2006年 

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  • 胸部悪性腫瘍の経皮的ラジオ波治療:局所制御率の中期成績

    第35回 日本IVR学会総会  2006年 

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  • 心臓・大動脈に近い肺腫瘍に対するラジオ波焼灼術の検討

    第35回 日本IVR学会総会  2006年 

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  • 肝細胞癌肺転移に対するラジオ波焼灼療法

    第35回 日本IVR学会総会  2006年 

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  • 生体肝移植後合併症に対し側副血行路塞栓術等、複合的にIVRを施行した1例

    第106回 日本医学放射線学会中国・四国地方会  2006年 

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  • DSMによる肺動脈塞栓後の肺ラジオ波焼灼療法:ブタの正常肺を用いた検討

    第35回 日本IVR学会総会  2006年 

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  • 頚動脈的エタノール注入にて良好な治療経過を得た手掌動静脈奇形の1例

    第35回 日本IVR学会総会  2006年 

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  • 肺RFAにおける予防的抗生物質使用の臨床的意義

    第7回 肺RFA談話会  2006年 

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  • 肺RFA治療後評価におけるFDG-PET検査の至適時期についての検討

    第19回 臨床核医学研究会  2006年 

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  • 軟部腫瘍のT1シンチグラフィ -疑陽性例の検討-

    第41回 日本核医学会中国・四国地方会  2006年 

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  • 経胸骨的に施行した腎癌肺転移に対するラジオ波凝固療法の1例

    第106回 日本医学放射線学会中国・四国地方会  2006年 

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  • 肝細胞癌肺転移に対して気管支動脈塞栓術、ラジオ波焼灼療法、放射線治療を組み合わせて治療した一例

    第20回 日本血管造影・IVR学会中国四国地方会  2006年 

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  • 肺ラジオ波治療後に生じた血胸に対して動脈塞栓術を施行した1例

    第20回 日本血管造影・IVR学会中国四国地方会  2006年 

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  • 肺RFA治療後評価におけるFDG-PET検査の至適時期についての検討

    第7回 肺RFA談話会  2006年 

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  • 肺結節性病変の良悪性鑑別におけるFDG PET/CT, DWIBS, T2WIの診断能の比較について

    第46回 日本核医学会学術総会  2006年 

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  • 各種癌に対するIVR治療

    岡山大学附属病院市民公開講座 切らずに治す癌・心臓病・脳卒中-岡大病院の最先端IVR治療-  2006年 

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  • 治療に難渋した腎AVMの1例

    第20回 日本血管造影・IVR学会中国四国地方会  2006年 

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  • 肺RFAにおける予防的抗生物質使用の臨床的意義

    第20回 日本血管造影・IVR学会中国四国地方会  2006年 

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  • Temperature measurement of the pleura during radiofrequency ablation of lung tumors

    RSNA 92nd scientific assembly & annual meeting 2006  2006年 

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  • Percutaneous CT-guided radiofrequency ablation for recurrent lung cancer after pulmonary resection

    RSNA 92nd scientific assembly & annual meeting 2006  2006年 

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  • RFA後の肺結節性病変におけるFDG-PETの診断能について

    第46回 日本核医学会学術総会  2006年 

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  • 軟部腫瘍のTIシンチグラフィ -疑腸性例の検討-

    第46回 日本核医学会学術総会  2006年 

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  • PTO及びBRTOにて止血し得た十二指腸静脈瘤破裂の1例

    第107回 日本医学放射線学会中国・四国地方会  2006年 

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  • 上腸間膜動脈塞栓症に血栓溶解療法が奏功した1例

    第107回 日本医学放射線学会中国・四国地方会  2006年 

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  • 原発性肺癌の病期診断におけるF-18 FDG PET/CTの診断能について

    第47回 日本肺癌学会総会  2006年 

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  • 肝細胞癌肺転移に対するラジオ波焼灼療法 (RFA)

    第47回 日本肺癌学会総会  2006年 

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  • 肺悪性腫瘍のラジオ波治療

    第47回 日本肺癌学会総会  2006年 

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  • 肺癌術後再発に対するラジオ波焼灼療法

    第47回 日本肺癌学会総会  2006年 

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  • Pulmonary tumors treated with percutaneous radiofrequency ablation: evaluation with follow up CT

    RSNA 91st scientific assembly & annual meeting 2005  2005年 

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  • CT-Guided Microwave Ablation for Treatment of Thoracic Tumors

    RSNA 2005  2005年 

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  • ラジオ波焼灼療法に伴う気胸および胸水の頻度とその危険因子の検討

    肺ラジオ波焼灼術における胸膜温度測定  2005年 

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  • 肺ラジオ波焼灼術における胸膜温度測定

    第46回 日本肺癌学会総会  2005年 

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  • 多血性腫瘍であるHCC、RCCからの肺転移に対するラジオ波焼灼療法

    第46回 日本肺癌学会総会  2005年 

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  • Sclerotherapy using polidocanol for venous malformations

    RSNA 91st scientific assembly & annual meeting 2005  2005年 

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  • 原発性肺癌に対してラジオ波焼灼療法と放射線療法を併用した2例

    第46回 日本肺癌学会総会  2005年 

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  • 肺ラジオ波焼灼療法後の空洞形成の検討

    第19回日本血管造影・IVR学会中国四国地方会  2005年 

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  • 人工喉頭留置のための気管食道瘻造設術

    第64回 日本医学放射線学会総会  2005年 

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  • 胸部悪性腫瘍に対するラジオ波焼灼療法後のCTによる経過観察-特に造影CTについて-

    第64回 日本医学放射線学会総会  2005年 

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  • 多血性腫瘍からの肺転移に対するラジオ波焼灼療法

    第104回 日本医学放射線学会中国四国地方会  2005年 

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  • 転移性肺腫瘍に対するマイクロ波凝固療法の初期経験

    第104回 日本医学放射線学会中国・四国地方会  2005年 

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  • Percutaneous transhepatic choledochojejunostomy using fine puncture needle for the treatment of complete biliary obstruction

    第34回 日本血管造影Intervertional Radiology学会総会  2005年 

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  • スフェレックスによる塞栓術が著効した子宮肉腫多発転移の1例

    第19回日本血管造影・IVR学会中国四国地方会  2005年 

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  • 肺腫瘍に対する経皮的ラジオ波焼灼療法の治療成績-midterm result-

    第19回日本血管造影・IVR学会中国四国地方会  2005年 

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  • 肺高血圧症を合併した肺動静脈瘻に対して塞栓術を施行した一例

    第19回 日本血管造影・IVR学会中国四国地方会  2005年 

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  • 十二指腸静脈瘤に対して予防的にPTOを施行した1例

    第104回 日本医学放射線学会中国四国地方会  2005年 

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  • 原発性肺癌に対する経皮的ラジオ波焼灼療法-2施設による中期成績-

    第46回 日本肺癌学会総会  2005年 

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  • DSMを用いたTAEが著効した子宮肉腫多発転移の1例

    第3回DSMシンポジウム  2005年 

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  • 肝膿瘍を契機として発症した肝静脈血栓症の2例

    第102回 日本医学放射線学会中国・四国地方会  2004年 

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  • インフルエンザ肺炎のCT所見

    第63回 日本医学放射線学会総会  2004年 

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  • 鎖骨下動脈仮性動脈瘤に対し直接穿刺による塞栓術を施行した1例

    第18回 日本血管造影・IVR学会中国四国地方会  2004年 

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  • 退形成性膵癌の1例

    第100回日本医学放射線学会・中国四国地方会  2003年 

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  • 乳頭状の充実成分により、悪性卵巣腫瘍と鑑別が必要であった骨盤腹膜炎の2例

    第17回 腹部放射線研究会  2003年 

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  • 健診で発見された肺犬糸状虫症の1例

    第101回日本医学放射線学会・中国四国地方会  2003年 

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  • 輸入脚症候群に対しステント留置した1例

    第17回日本血管造影・IVR学会・中国四国地方会  2003年 

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  • 多房性嚢胞性腫瘤を呈した胆嚢癌の1例

    第99回日本医学放射線学会中国四国地方会  2002年 

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  • 脱落膜化した異所性内膜が充実部分を呈した内膜症性嚢胞の1例 -画像と病理の対比-

    第21回 日本画像医学会  2002年 

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  • HCCに対するTAE、RFA併用療法の初期経験

    第16回日本血管造影・IVR学会中国四国地方会  2002年 

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  • 虫垂と両側卵巣に粘液性腫瘍を認めた腹膜偽粘液腫の1例

    第98回日本医学放射線学会中国四国地方会  2002年 

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  • エストロゲン産生を認めた転移性卵巣腫瘍の1例

    第16回 腹部放射線研究会  2002年 

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  • 画像上浸潤性発育を示し悪性腫瘍と鑑別困難であった腎血管腫の1例

    第16回 腹部放射線研究会  2002年 

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  • T1WI冠状断における前十字靭帯内部の線状高信号の臨床的意義

    第38回日本医学放射線学会秋季臨床大会  2002年 

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  • USガイド下に窮刺吸引を施行し膝窩動脈外膜嚢腫の1例

    第15回 日本血管造影Intervertional Radiology学会中国四国地方会  2001年 

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  • リザーバー治療中総肝動脈に巨大な仮性動脈瘤を形成した胃癌肝転移の1例

    リザーバー研究会  2001年 

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  • 妊娠に合併した骨盤内腫瘍の1例

    第22回 岡山画像診断懇話会  2001年 

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  • 特異な形態を呈し蛋白漏出性胃腸症をきたした早期胃癌の1例

    第15回 腹部放射線研究会  2001年 

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  • ミノマイシンを用いた肝嚢胞硬化療法

    第15回日本血管造影・IVR学会中国四国地方会  2001年 

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  • T1強調冠状断における前十字靭帯の線状高信号の臨床的意義

    日本医学放射線学会中国四国地方会  2001年 

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  • ネコひっかき病の2例

    第97回日本医学放射線学会中国四国地方会  2001年 

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  • 虫垂周囲膿瘍術後の遺残虫垂結石による再発性膿瘍にCT下ドレナージを施行した1例

    日本血管造影・IVR学会中国四国地方会  2000年 

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  • Aggressive osteoblastomaの1例

    第94回日本医学放射線学会中国四国地方会  2000年 

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  • 腰椎硬膜外膿瘍の5例

    第94回日本医学放射線学会中国四国地方会  2000年 

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  • 膵管狭細型慢性膵炎の1例

    第14回腹部放射線研究会  2000年 

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  • 異所性に膵管癌が併存したintraductal papillary musinous tumor of the pancreasの1例

    第14回 腹部放射線研究会  2000年 

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  • 卵巣Yolk sac tumorの1例

    第95回日本医学放射線学会中国四国地方会  2000年 

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  • 骨軟骨病変と鑑別を要した膝関節正常変異の1例

    第95回日本医学放射線学会中国四国地方会  2000年 

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▼全件表示

受賞

  • Best Reviewer Award

    2017年   Acta Medica Okayama  

    郷原 英夫

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  • 優秀論文賞

    2016年   日本IVR学会   Percutaneous CT-guided Radiofrequency Ablation for Renal Cell Carcinoma in von Hippel-Lindau Disease: Midterm Results

    郷原 英夫

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  • Certificate of Merit

    2008年   北米放射線学会  

    郷原 英夫

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    受賞国:日本国

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  • 優秀発表賞

    肺癌学会   Stage I 肺癌に対するラジオ波焼灼療法-2施設による中期成績-

    郷原 英夫

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