Faculty Profiles - KAWAZU Toshiyuki

Papers - KAWAZU Toshiyuki

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CT値を用いた歯原性嚢胞の鑑別の有用性と適応例の検討

久富美紀, 上原京憲, 河津俊幸, 岡田俊輔, 竹下洋平, 藤倉満美子, 吉田沙織, 藤田麻里子, 柳文修, 浅海淳一

岡山歯学会雑誌 39 ( 2 ) 37 - 38 2020.12

転移学習を応用したディープ・ラーニングによる齲蝕画像診断の実験的研究

河津俊幸, 竹下洋平, 岡田俊輔, 久富美紀, 浅海淳一

岡山歯学会雑誌 39 ( 2 ) 39 - 39 2020.12

Prediction of nodal metastasis based on intraoral sonographic findings of primary lesion in early-stage tongue cancer Reviewed

Shintaro Kawano, Taichi Hattori, Yurie Mikami, Toru Chikui, Toshiyuki Kawazu, Taiki Sakamoto, Yasuyuki Maruse, Shoichi Tanaka, Eiki Hamada, Megumi Hiwatashi, Yurika Shiraishi, Kazunari Oobu, Tamotsu Kiyoshima, Seiji Nakamura

International Journal of Oral and Maxillofacial Surgery in print 2020.6

Incidental findings in the thyroid gland on computed tomography images of the oral and maxillofacial region

Abdullah Khasawneh, Yohei Takeshita, Miki Hisatomi, Toshiyuki Kawazu, Mariko Fujita, Shunsuke Okada, Yuri Namba, Yudai Shimizu, Yoshinobu Yanagi, Junichi Asaumi

ONCOLOGY LETTERS 19 ( 3 ) 2005 - 2010 2020.3

Language：English Publishing type：Research paper (scientific journal) Publisher：SPANDIDOS PUBL LTD

The numbers of abnormal findings incidentally detected in adjacent regions are increasing with advances in imaging modalities. The present study aimed to examine the prevalence and characteristics of incidental findings in the thyroid gland on computed tomography (CT) images of the oral and maxillofacial region. CT scans of the oral and maxillofacial region in patients obtained between January 2012 and December 2016 were retrospectively reviewed. Images that revealed incidental findings in the thyroid gland, including nodules, were recorded, together with the sizes and characteristics of the findings. The Japan Association of Breast and Thyroid Sonology (JABTS) guidelines were used for classification. The rate of descriptions of these findings in the radiographic interpretation reports were also examined. Of the 1,135 patients examined, 326 (28.7%) had several types of incidental findings. In particular, 169 (14.9%) of the 1,135 patients had nodules >5 mm in diameter, for which further careful examination is recommended in the JABTS guideline. The description rate for nodules >5 mm in diameter in the radiographic interpretation reports was 30.8% (52/169 patients), of whom 17.3% (9/52 patients) were referred to the endocrinology department for further careful examination. Incidental findings in the thyroid gland were relatively common on CT images of the oral and maxillofacial region. Oral radiologists tend to focus specifically on the oral and maxillofacial region during diagnosis on oral and maxillofacial CT images, but should pay the same careful attention to observe adjacent regions, such as the thyroid gland.

DOI： 10.3892/ol.2020.11298

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鼻咽腔に発生した若年性血管線維腫3例の比較検討

清水雄大, 村上純, 河津俊幸, 久富美紀, 藤田麻里子, 竹下洋平, 岡田俊輔, 難波友里, 柳文修, 浅海淳一

歯科放射線 59 ( 増刊 ) 57 - 57 2019.6

舌エコーの画像所見による潜在的頸部リンパ節転移の予測

服部多市, 川野真太郎, 三上友里恵, 筑井徹, 河津俊幸, 松原良太, 後藤雄一, 金子直樹, 坂本泰基, 橋口有真, 神野哲平, 丸瀬靖之, 田中翔一, 大部一成, 中村誠司

日本口腔科学会雑誌 67 ( 2 ) 200 - 201 2018.7

Estimation of prognosis of tongue cancer using tumor depth and margin shape obtained from ultrasonography Reviewed

Sitti Fadhillah Oemar Mattalitti, Toshiyuki Kawazu, Shintaro Kawano, Tatsuya Ikari, Hiroko Wada, Kazunori Yoshiura

ORAL RADIOLOGY 33 ( 2 ) 101 - 107 2017.5

Language：English Publishing type：Research paper (scientific journal) Publisher：SPRINGER

To evaluate the feasibility of using ultrasound-obtained tumor depth (TD) and margin shape (MS) to predict the prognosis of tongue cancer.
Fifty-two Japanese patients with tongue cancer who underwent ultrasound examination between 2007 and 2012 were retrospectively evaluated. TD was measured at the deepest portion of the tumor. MS was classified as "pressure," "wedge-shaped," or "permeated." Prognosis was assessed by local recurrence, lymph node metastasis, and overall survival rate. We classified the patients into a good prognosis group and poor prognosis group. Relationships among TD, MS, and patient prognosis were evaluated using Spearman rank correlation. A regression formula to predict prognosis using TD and MS was derived.
The correlation between TD and MS was significant (Spearman rank correlation rho = 0.552, p < 0.01). Using a structure matrix, we identified the contribution of both predictors from an ultrasound image. The contribution of TD was 0.796, while that of MS was better at 0.906. The prognosis could be predicted using the following regression formula: , where D prognosis (risk probability), x = TD (mm), and y = MS (grade). The average value for good risk probability was -0.254 (standard deviation, 0.962), while that for poor risk probability was 0.566 (standard deviation, 1.08) (p < 0.05). The cut-off value for classifying cases was -0.00169. Using the formula above, 73.1 % of patients in the poor prognosis group were correctly classified.
MS and TD are useful predictors of tongue cancer prognosis.

DOI： 10.1007/s11282-016-0251-y

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巨舌を呈した舌対称性脂肪腫症の1例 Reviewed

見立英史, 川野真太郎, 清島保, 三上友里恵, 後藤雄一, 河津俊幸, 池邉哲郎, 中村誠司

日本口腔腫瘍学会誌 28 ( 4 ) 293 - 298 2016.12

Language：Japanese Publisher：(一社)日本口腔腫瘍学会

舌対称性脂肪腫症(SLT)は、成熟した脂肪組織が両側の舌筋内へ浸潤性増殖する疾患と定義される。今回われわれは、巨舌を呈したSLTの症例を経験したので、文献的考察を加えて報告する。患者は、両側舌縁部に無痛性で弾性軟、多発性の腫瘤を認めた71歳の男性である。舌縁部の外向性腫瘤により、患者の舌幅は下顎の歯列弓幅よりも広く、いわゆる巨舌を呈していた。両側舌縁部の腫瘤は、MRIのT1およびT2強調画像で高信号、T2脂肪抑制像で信号低下を示した。生検組織の病理組織学的診断は脂肪腫であった。病変が対称性はないものの、両側の舌縁部にあることから、SLTと診断した。慢性心房細動に対して抗凝固薬を内服しており、術後の出血および腫脹による気道閉塞が懸念されたため、左右2回に分けて全身麻酔下に腫瘍減量術を行った。切除物の病理組織検査では、成熟した脂肪組織が舌筋組織内へ浸潤性増殖している所見がみられ、病理組織学的診断はSLTであった。術後2年経過したが、増大所見は認めない。(著者抄録)

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Dentigerous cysts with calcification mimicking odontogenic tumors: differential diagnosis by CT Reviewed

Mayumi Shimizu, Dai Ogawa, Kazutoshi Okamura, Toshiyuki Kawazu, Toru Chikui, Kazunori Yoshiura

ORAL RADIOLOGY 31 ( 1 ) 14 - 22 2015.1

Language：English Publishing type：Research paper (scientific journal) Publisher：SPRINGER

This study aimed at clarifying whether we can differentiate dentigerous cysts with calcified substances from other odontogenic tumors that include calcification and the crown of an unerupted tooth by CT findings.
We retrospectively selected histopathologically confirmed cases that included calcified substances and the crown of an unerupted tooth inside. There were 22 cases with eight pathological categories. Besides seven odontogenic tumors, we included dentigerous cysts, which were usually recognized without calcification within the lesions. We divided the cases into two groups: 14 cases of odontogenic tumors and 8 cases of dentigerous cysts. Cases were analyzed for various CT findings such as continuity with the alveolar crest, bone sclerosis around the lesion, and sizes and shapes of high CT value substances, as well as demographic factors. Comparisons between the groups for each analytical factor were performed.
Dentigerous cysts with dystrophic calcification showed unique CT findings such as bone sclerosis around the lesion, continuity with the alveolar crest, and small scattered calcified substances near the crown of an unerupted tooth, compared with typical dentigerous cysts and other odontogenic tumors. On the other hand, odontogenic tumors showed various patterns in the location and distribution of high CT value substances, and we could only differentiate odontoma using its very high CT values.
Although the patterns of calcification were not the main characteristic findings, it may be possible to differentiate dentigerous cysts with dystrophic calcification from odontogenic tumors by their other characteristic CT findings, and unnecessary extensive surgery can also be avoided.

DOI： 10.1007/s11282-014-0173-5

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Carcinoma ex pleomorphic adenoma of the upper lip: a case of an unusual malignant component of squamous cell carcinoma. International journal

Eiji Mitate, Shintaro Kawano, Tamotsu Kiyoshima, Toshiyuki Kawazu, Toru Chikui, Yuichi Goto, Ryota Matsubara, Seiji Nakamura

World journal of surgical oncology 11 234 - 234 2013.9

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Squamous cell carcinoma (SCC) as the malignant component of carcinoma ex pleomorphic adenoma (CXPA) occurring in upper lip is rare. CASE REPORT: A 55-year-old male patient presented with an asymptomatic mass of the upper lip that had noticed 8 years previously. The mass was clinically suspected to be a benign salivary gland tumor based on palpation and magnetic resonance imaging findings. A needle biopsy was then carried out, and the pathological diagnosis was pleomorphic adenoma. The tumor was removed under general anesthesia. Histopathological examination revealed well-demarcated tumor tissues showing typical histologic features of pleomorphic adenoma. However, SCC tissue with several mitotic figures was found in the central area of the tumor tissue. The tumor was finally diagnosed as CXPA. There was no evidence of recurrence or metastasis 6 years postoperatively. CONCLUSION: This is the first report of CXPA of the upper lip with an unusual malignant component of SCC.

DOI： 10.1186/1477-7819-11-234

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Carcinoma ex pleomorphic adenoma of the upper lip: A case of an unusual malignant component of squamous cell carcinoma

Eiji Mitate, Shintaro Kawano, Tamotsu Kiyoshima, Toshiyuki Kawazu, Toru Chikui, Yuichi Goto, Ryota Matsubara, Seiji Nakamura

World Journal of Surgical Oncology 11 2013.9

Publishing type：Research paper (scientific journal)

Background: Squamous cell carcinoma (SCC) as the malignant component of carcinoma ex pleomorphic adenoma (CXPA) occurring in upper lip is rare.Case report: A 55-year-old male patient presented with an asymptomatic mass of the upper lip that had noticed 8 years previously. The mass was clinically suspected to be a benign salivary gland tumor based on palpation and magnetic resonance imaging findings. A needle biopsy was then carried out, and the pathological diagnosis was pleomorphic adenoma. The tumor was removed under general anesthesia. Histopathological examination revealed well-demarcated tumor tissues showing typical histologic features of pleomorphic adenoma. However, SCC tissue with several mitotic figures was found in the central area of the tumor tissue. The tumor was finally diagnosed as CXPA. There was no evidence of recurrence or metastasis 6 years postoperatively.Conclusion: This is the first report of CXPA of the upper lip with an unusual malignant component of SCC. © 2013 Mitate et al.; licensee BioMed Central Ltd.

DOI： 10.1186/1477-7819-11-234

見立英史, 大部一成, 吉賀大午, 川野真太郎, 河津俊幸, 清島保, 豊嶋健史, 北村亮二, 中村誠司

日本口腔腫瘍学会誌 24 ( 2 ) 55 - 61 2012.6

Language：Japanese Publisher：(一社)日本口腔腫瘍学会

腺扁平上皮癌は口腔領域ではまれな悪性腫瘍である。われわれは下顎歯肉腺扁平上皮癌の1例を経験した。症例は74歳男性。2009年1月初旬、左側下顎歯肉の疼痛と摂食障害を主訴に当科初診。初診時、左側下顎歯肉に55×25mm、弾性軟、暗紫色で易出血性の腫瘤を認めた。また左側オトガイ部に知覚鈍麻を認めた。CT画像では下顎管に達する骨吸収を認めた。頸部超音波検査で2個の左側顎下リンパ節に転移が疑われた。生検組織では扁平上皮癌の要素と、ジアスターゼ処理PAS染色にて粘液産生細胞を認める腺癌要素が見られた。以上より、左側下顎歯肉腺扁平上皮癌(T4N2bM0)と診断した。既往の間質性肺炎の状況から手術が困難であることと本人の希望により、根治的放射線化学療法としてUFT内服と放射線外照射を施行した。その後、両肺野、腹部と腋下部の皮膚に多発遠隔転移を認めた。4月末日呼吸状態悪化により永眠した。(著者抄録)

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A new method for evaluating perceptible contrast information in digital intraoral radiographic systems Reviewed

Kazutoshi Okamura, Kazunori Yoshiura, Masato Tatsumi, Toshiyuki Kawazu, Toru Chikui, Mayumi Shimizu, Tazuko K. Goto

ORAL RADIOLOGY 27 ( 2 ) 98 - 101 2011.12

Language：English Publishing type：Research paper (scientific journal) Publisher：SPRINGER

Objectives To evaluate four digital intraoral radiographic systems using perceptibility curves (PCs) in a grayscale domain and to clarify the usefulness of this new method.
Methods Four systems were evaluated, namely the CDR, Dixel, Digora, and Digora Optime. An aluminum phantom with 12 steps was radiographed using all four systems. The mean gray values and their standard deviations were measured for each step as well as the background of the images for each device. The minimum perceptible gray level differences at a given exposure were calculated from the mean gray values and standard deviations, and a PC in the grayscale domain was constructed at each exposure for all devices. The area under the PC was assumed to be the perceptible contrast information at that exposure for each system. By combining the PCs at all exposures for each system, the maximum perceptible contrast information in each system was calculated. The correlation between the perceptible contrast information and the number of perceptible holes by observers at each exposure was examined for all four digital systems.
Results The Dixel and Digora Optime showed similar PCs, and their minimum perceptible gray level differences were the smallest among the systems. The correlation between the number of perceptible holes and the areas under the PCs at each exposure for the four systems was relatively high (r = 0.92).
Conclusions The areas under the PCs in a grayscale domain were highly correlated with observer performance. This method can be used to evaluate the image quality of new digital systems.

DOI： 10.1007/s11282-011-0068-7

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Prediction and monitoring of the response to chemoradiotherapy in oral squamous cell carcinomas using a pharmacokinetic analysis based on the dynamic contrast-enhanced MR imaging findings Reviewed

Toru Chikui, Shintaro Kawano, Toshiyuki Kawazu, Masamitsu Hatakenaka, Syouzou Koga, Masahiro Ohga, Yoshio Matsuo, Syunya Sunami, Tsuyoshi Sugiura, Yoshiyuki Shioyama, Makoto Obara, Kazunori Yoshiura

EUROPEAN RADIOLOGY 21 ( 8 ) 1699 - 1708 2011.8

Language：English Publishing type：Research paper (scientific journal) Publisher：SPRINGER

To evaluate whether a pharmacokinetic analysis is useful for both predicting and monitoring the response to chemoradiotherapy (CRT) in oral cancer.
Patients with oral squamous cell carcinoma treated with preoperative CRT and surgery were enrolled. They underwent dynamic contrast-enhanced MRI before (n = 23), and after CRT (n = 20). We estimated four parameters: arrival time of contrast medium (TA), exchange rate constant from the extracellular extravascular space (EES) to plasma (k(ep)), elimination of contrast medium from the central compartment (k(el)) and an amplitude scaling constant (AH) using the Brix model. The histological evaluation of the effects of CRT was performed according to Ohboshi and Shimosato's classification. We analysed the correlation between the parameters and the histological evaluation.
The pre-CRT AH between the responders and non-responders was significantly different (P = 0.046), however, the three parameters (TA, K-ep, K-el) were not significantly different among the groups (P = 0.76, P = 0.60, P = 0.09). As AH decreased, the tumour response improved. The change in the AH between the pre- and post-CRT of responders was significantly higher than that of non-responders (P = 0.043).
The AH, which is affected by the ratio of the EES, was an important parameter for predicting and monitoring the tumour response to CRT.

DOI： 10.1007/s00330-011-2102-x

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A case of osteoporotic bone marrow defect in the mandible

OKA Shoji, KUBOTA Yasutaka, ISHIBASHI Hiroaki, KOBAYASHI Ieyoshi, KAWAZU Toshiyuki, SHIRASUNA Kanemitsu

Journal of Oral Surgery Society of Japan 57 ( 5 ) 264 - 268 2011.5

Language：Japanese Publisher：Japanese Society of Oral and Maxillofacial Surgeons

Osteoporotic bone marrow defect （OBMD） is a rare benign jaw lesion consisting of hematopoietic bone marrow, which results in a focal bone defect. The present report describes a case of OBMD in the mandibular molar region of a 53 year-old-woman. A panoramic radiograph showed the presence of an undefined round,thumb-sized radiolucent lesion in the lower left first molar region. The density inside of the lesion was −37.7 Hounsfield units on CT scanning, suggesting fat tissue. The biopsy specimens revealed fat tissue with thin bone trabeculae and hematopoietic cell infiltration. The clinical course has been uneventful without any treatment for 4 years.

DOI： 10.5794/jjoms.57.264

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Imaging diagnosis of salivary gland tumor Invited Reviewed

NAKAYAMA Eiji, OHUCHI Tomoyuki, KAKU Tohru, SHIBATA Takanori, ARISUE Makoto, NAGAYASU Hiroki, ABIKO Yoshihiro, UENO Mayumi, KAWAZU Toshiyuki, YOSHIURA Kazunori, ASAKA Yuichiro, UEDA Michihiro, YAMASHITA Tetsuro, NAKAMORI Kenji, HIRATSUKA Hiroyoshi, HARIYA Yasushi, SEKIGUCHI Takashi

Journal of Japanese Society of Oral Oncology 23 ( 3 ) 59 - 68 2011.1

Language：Japanese Publisher：Japanese Society of Oral Oncology

The histopathological diagnosis of salivary gland tumors is sometimes difficult, because the tumors have various histologic patterns and manifold tissue components coexist in a histologic pattern. Therefore, the differential imaging diagnosis of a benign and malignant tumor in the salivary gland is also sometimes difficult.<br>A salivary gland lesion in which the border is slightly unclear is sometimes a malignant tumor, even though the borderline looks almost clear on the images. Therefore, in the imaging diagnosis of salivary gland tumors, the clearness of the boundary on the images is very important and its cautious interpretation is essential; the clearness should be judged not by CT but by ultrasonography and MRI. Moreover, the CT and MRI images should be observed by optimal indication on a DICOM Viewer, if possible.<br>Regarding major salivary gland tumors: over 70% of parotid gland tumors are benign, 40% of submandibular gland tumors are malignant, and 80% of sublingual tumors are malignant. These figures are important when interpreting diagnostic images of major salivary gland tumors. A parotid gland tumor in which the border is not always clear should be suspected as malignant. A lesion that is confirmed as a sublingual gland tumor on diagnostic images should be diagnosed as a malignant tumor.<br>Concerning minor salivary gland tumors: when the tumor is small, a borderline is often clear even though the tumor is malignant. Hence, imaging findings of a lesion with a clear boundary are not evidence of a benign tumor in the minor salivary gland. In malignant salivary gland tumors of the palatal region, particular attention should be paid to weak bone invasion, which cannot be detected on imaging findings. In the lip and buccal region, ultrasonography is the most effective imaging modality. It is necessary to remember that mucoepidermoid carcinoma occurs also in the jawbones.

DOI： 10.5843/jsot.23.59

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Effect of clenching on T2 and diffusion parameters of the masseter muscle. International journal

Toru Chikui, Tomoko Shiraishi, Takahiro Ichihara, Toshiyuki Kawazu, Masamitsu Hatakenaka, Yukiko Kami, Kenji Yuasa, Kazunori Yoshiura

Acta radiologica (Stockholm, Sweden : 1987) 51 ( 1 ) 58 - 63 2010.2

Language：English Publishing type：Research paper (scientific journal)

BACKGROUND: Persistent muscle contractions during clenching are considered to be one reason for temporomandibular disorders. However, no report has evaluated the effect of clenching on the masticatory muscles, as measured by magnetic resonance imaging (MRI). PURPOSE: To investigate whether clenching has an effect on either T(2) or the coefficients for diffusion of the masseter muscles (MM), and to evaluate the effect of the distribution of bite force on such indices. MATERIAL AND METHODS: Twenty-three subjects were examined. Bite force was measured by a pressure-sensitive sheet, and the force of the right and the left sides was calculated. MRI was used to evaluate T(2), the apparent diffusion coefficient (ADC), and the primary (lambda(1)), secondary (lambda(2)), and tertiary eigenvalues (lambda(3)). These indices on the stronger side of the bite force were compared to those on the weaker side. Thereafter, the indices were compared between at rest and during clenching. RESULTS: There was no significant difference in any of the indices (T(2), ADC, lambda(1), lambda(2), and lambda(3)) between the side of stronger bite force and the side with weaker. T(2) increased by clenching, and the difference was significant in the side with stronger bite force (P = 0.006). ADC, lambda(1), lambda(2), and lambda(3) increased significantly by clenching (P <0.01, P <0.01, P <0.01, and P <0.01, respectively) on both sides. The percentage of change of lambda(2) by clenching was 26.2+/-15.7% on the stronger side and 26.9+/-18.6% on the weaker side, which was significantly greater than either that of lambda(1) or lambda(3). CONCLUSION: The coefficients for diffusion of the MM were sensitive to change by clenching, and lambda(2) was the most sensitive. Moreover, the relative distribution of the bite forces had no effect on any of the indices.

DOI： 10.3109/02841850903280508

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A QUANTITATIVE ANALYSIS OF SONOGRAPHIC IMAGES OF THE SALIVARY GLAND: A COMPARISON BETWEEN SONOGRAPHIC AND SIALOGRAPHIC FINDINGS Reviewed

Toru Chikui, Mayumi Shimizu, Toshiyuki Kawazu, Kazutoshi Okamura, Tomoko Shiraishi, Kazunori Yoshiura

ULTRASOUND IN MEDICINE AND BIOLOGY 35 ( 8 ) 1257 - 1264 2009.8

Language：English Publishing type：Research paper (scientific journal) Publisher：ELSEVIER SCIENCE INC

We performed three quantitative analyses (particle analysis, fractional Brownian motion [fBM] model analysis, two-dimensional [2-D] fractal analysis) of the ultrasonographic (US) images of the salivary gland and evaluated whether the obtained indices correlated with the sialographic stage of Rubin-Holt. Our study included 192 patients suspected of having Sjogren's syndrome (SS). In 89 patients, sialography demonstrated abnormal findings. Based on a particle analysis, we calculated both the average size of the particles (avg-area) and the area ratio to evaluate the presence of hypoechoic areas and echogenic lines, which are characteristic of SS. According to the fBM model, we calculated the Hurst index of the original image (Hurst-ori) and the background-subtracted image (Hurst-bs) to evaluate the complexity of the pixel value distribution. We also obtained the 2-D fractal dimension (2-D-FD) to evaluate the complexity of the contour lines. We entered these indices of the parotid glands (PG) into a logistic regression analysis and evaluated which indices were useful predictors for detecting all abnormal sialographic stage. Significant differences were observed between the normal and abnormal groups in all five indices of the PG (Mann-Whitney U test) and all five indices were correlated with the Rubin-Holt stage (Spearman's Rank Correlation Test). As the Rubin-Holt stage became more severe, both the Hurst-ori and 2-D-FD became smaller. Alternatively, the Hurst-bs, avg-area, and area ratio became higher. Three indices (avg-area, area ratio and Hurst-ori) were selected as useful predictors for detecting abnormal sialographic stages. This quantitative analysis system is therefore considered to have potentially useful clinical applications for the detection of abnormal sialographic findings. (E-mail: chikui@rad.dent.kyushu-u.ac.jp) (C) 2009 World Federation for Ultrasound in Medicine & Biology.

DOI： 10.1016/j.ultrasmedbio.2009.03.005

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副耳下腺に生じた多形腺腫の1例 Reviewed

見立英史, 大部一成, 笹栗正明, 中村典史, 川野真太郎, 小林家吉, 河津俊幸, 中村誠司

日本口腔腫瘍学会誌 20 ( 4 ) 291 - 296 2008.12

Language：Japanese Publisher：(一社)日本口腔腫瘍学会

われわれは副耳下腺の多形腺腫を経験した。2004年3月、20歳代後半の男性が右側頬部の腫瘤を主訴に来院した。MRI、超音波検査により副耳下腺部の腫瘤の存在を認めた。術前の針生検では多形腺腫が最も疑われたが、確定するにはいたらなかったため、同年9月手術により摘出した。腫瘤は耳下腺から独立して咬筋の外側にあり、顔面神経頬骨枝に囲まれていたが、容易に摘出でき、術後に顔面神経障害は認めなかった。摘出物の病理組織学的診断は多形腺腫であった。(著者抄録)

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良性腫瘍(臨床) 当科における舌下腺腫瘍の臨床統計的検討

梅津健太郎, 川野真太郎, 中尾祐, 大部一成, 中山英二, 河津俊幸, 小林家吉, 清島保, 中村誠司

日本口腔科学会雑誌 57 ( 1 ) 120 - 120 2008.1

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