研究者詳細 - 川上　佳夫

論文 - 川上　佳夫

分割表示 127 件中 81 - 100 件目／全件表示 >>

Classical Vohwinkel syndrome with heterozygous p.Asp66His mutation in GJB2 gene: Second Asian case. 国際誌

Kenta Ikeda, Takuya Takeichi, Yasutoshi Ito, Yoshio Kawakami, Yuki Nakagawa, Seiko Naito, Osamu Yamasaki, Masashi Akiyama, Shin Morizane

The Journal of dermatology 47 ( 10 ) e352-e354 2020年10月

Familial nasal dermoid sinus cysts skipping generations. 国際誌

Kimiko Nishigaki, Osamu Yamasaki, Yoshio Kawakami, Minori Sasakura, Tomoko Miyake, Aiji Ohtsuka, Junko Kousogabe, Shin Morizane

The Journal of dermatology 47 ( 10 ) e373-e375 2020年10月

在宅医と連携した進行期悪性黒色腫

石井芙美, 山崎修, 加持達弥, 川上佳夫, 森実真, 片山英樹, 國末充央, 武藤純, 小森栄作

Skin Cancer 35 ( 1 ) 1 - 5 2020年6月

Atezolizumab-induced lichen planus pemphigoides in a patient with metastatic non-small-cell lung cancer. 国際誌

Haruka Senoo, Yoshio Kawakami, Emi Yokoyama, Osamu Yamasaki, Shin Morizane

The Journal of dermatology 47 ( 4 ) e121-e122 2020年4月

A case of leukocytoclastic vasculitis occurred during combination chemotherapy of cetuximab and paclitaxel

Yohei Yasutomi, Yoshio Kawakami, Minori Sasakura, Taisuke Kanno, Yuko Fujimoto, Tomoko Miyake, Osamu Yamasaki, Shin Morizane

Nishinihon Journal of Dermatology 82 ( 4 ) 271 - 275 2020年

Pediatric-onset annular pustular psoriasis in a patient with Down syndrome. 国際誌

Anri Morita, Yoshio Kawakami, Tatsuya Kaji, Yoji Hirai, Tomoko Miyake, Masayuki Takahashi, Osamu Yamasaki, Kazumitsu Sugiura, Shin Morizane

The Journal of dermatology 46 ( 10 ) e367-e368 2019年10月

訪問診療専門クリニックと連携した進行期悪性黒色腫

石井芙美, 山崎修, 加持達弥, 川上佳夫, 片山英樹, 國末充央, 武藤純, 小森栄作

日本皮膚悪性腫瘍学会学術大会プログラム・抄録集 35回 114 - 114 2019年4月

直接作用型抗ウイルス薬によるC型肝炎治療後も症状が持続していた形質細胞性口唇炎の1例

永瀬喬之, 梶田藍, 小田和歌子, 原裕一, 川上佳夫

皮膚科の臨床 61 ( 3 ) 419 - 422 2019年3月

Local desensitization and progression of multiple fixed drug eruption. 国際誌

Seiko Mitsui, Chieko Katayama, Yumi Aoyama, Yoshiko Mizukawa, Michiyo Kuyama, Yoshio Kawakami

European journal of dermatology : EJD 28 ( 3 ) 378 - 380 2018年6月

Unopposed IL-36 Activity Promotes Clonal CD4+ T-Cell Responses with IL-17A Production in Generalized Pustular Psoriasis. 国際誌

Akiko Arakawa, Sigrid Vollmer, Petra Besgen, Adrian Galinski, Burkhard Summer, Yoshio Kawakami, Andreas Wollenberg, Klaus Dornmair, Michael Spannagl, Thomas Ruzicka, Peter Thomas, Jörg C Prinz

The Journal of investigative dermatology 138 ( 6 ) 1338 - 1347 2018年6月

記述言語：英語掲載種別：研究論文（学術雑誌）

Generalized pustular psoriasis (GPP) is the most severe psoriasis variant. Mutations in the IL-36 antagonist IL36RN, in CARD14 or AP1S3 provide genetic evidence for autoinflammatory etiology but cannot explain its pathogenesis completely. Here we demonstrate that unopposed IL-36 signaling promotes antigen-driven and likely pathogenic T-helper type 17 (Th17) responses in GPP. We observed that CD4+ T cells in blood and skin lesions of GPP patients were characterized by intense hyperproliferation, production of the GPP key mediator, IL-17A, and highly restricted TCR repertoires with identical T-cell clones in blood and skin lesions, indicating antigen-driven T-cell expansions. The clonally expanded CD4+ T cells were major producers of IL-17A. IL-36 signaling substantially enhanced TCR-mediated proliferation of CD4+ T cells. Moreover, GPP patients showed preferences for HLA-DRB1∗14, HLA-DQB1∗05, and HLA-DQB1∗03. We conclude that in GPP unopposed IL-36 signaling and certain HLA-class II alleles may cooperate in promoting antigen-driven Th17 responses, which in the obvious absence of exogenous triggers may reflect autoimmune reactions. This study reveals a pathogenic pathway where innate immune dysregulation promotes T-cell-mediated inflammation in GPP.

DOI： 10.1016/j.jid.2017.12.024

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Anaphylaxis due to ingestion of jellyfish with possible evidence of epicutaneous sensitization. 国際誌

Yoshio Kawakami, Shu Taga

The Journal of dermatology 45 ( 1 ) e23-e24 2018年1月

Case of inflammatory tinea corporis affecting the dorsal surface of the thumb in a nail salon technician. 国際誌

Yoshio Kawakami, Shuichiro Hirano, Seiko Mitsui, Michiyo Kuyama, Akiko Nishibu, Kazushi Anzawa, Takashi Mochizuki

The Journal of dermatology 44 ( 11 ) e294-e295 2017年11月

Successful use of etoposide for pyoderma gangrenosum associated with myelodysplastic syndrome and trisomy 8: cytokine profiles during treatment. 国際誌

Dan Fujiwara, Toshihisa Hamada, Osamu Yamasaki, Yasuhisa Sando, Kyosuke Saeki, Nobuharu Fujii, Yoshio Kawakami, Keiji Iwatsuki

European journal of dermatology : EJD 27 ( 5 ) 525 - 527 2017年10月

A case of porokeratosis ptychotropica: successful treatment with topical 5% imiquimod cream

Y. Kawakami, S. Mitsui

Clinical and Experimental Dermatology 42 ( 7 ) 839 - 841 2017年10月

An unusual clinical presentation of lupus erythematosus tumidus localized on the thigh

T. Hashimoto, Y. Kawakami, H. Wakabayashi, W. Oda, T. Hamada, H. Doi, Y. Aoyama, K. Iwatsuki

Clinical and Experimental Dermatology 42 ( 6 ) 638 - 641 2017年8月

Candida albicans-induced pustular lesions in mice. 国際誌

Yoshio Kawakami, Toshiyuki Yamamoto

The Journal of dermatology 44 ( 5 ) 596 - 597 2017年5月

Persistent elevation of serum interleukin-6 and serum amyloid A levels in patients with recessive dystrophic epidermolysis bullosa. 国際誌

Shin Morizane, Kazuko Mizuno, Tetsuya Takiguchi, Satoko Ogita, Yoshinobu Nishida, Yoshio Kawakami, Keiji Iwatsuki

European journal of dermatology : EJD 27 ( 1 ) 80 - 81 2017年2月

A case of disseminated superficial porokeratosis with inflammatory stage

Yoshio Kawakami, Seiko Mitsui, Kenji Imajo

Nishinihon Journal of Dermatology 79 ( 6 ) 558 - 561 2017年

A Case of Streptobacillus moniliformis Infection with Cutaneous Leukocytoclastic Vasculitis.

Yoshio Kawakami, Takashi Katayama, Masayuki Kishida, Wakako Oda, Yasuro Inoue

Acta medica Okayama 70 ( 5 ) 377 - 381 2016年10月

記述言語：英語

A 71-year-old man presented with a high fever, polyarthralgia, petechiae and palpable purpura accompanied by livedoid change on his legs and feet. Histopathological findings of the purpura revealed perivascular infiltration of neutrophils, mononuclear cells, and nuclear debris, and extravasation of red cells mainly in the upper dermis: all signs consistent with leukocytoclastic vasculitis. Small vessel thrombi, which are characteristic features of septic vasculopathy, were also observed. Direct immunofluorescence showed negative results. Blood culture revealed the growth of gram-negative bacilli. Subsequently, 16S rRNA sequencing of DNA confirmed the organism as Streptobacillus moniliformis, which is the causative pathogen of rat-bite fever. He had frequently encountered wild rats in his house although there was no evidence of rat bite on his body. Empiric therapy with intravenous administration of ceftriaxone in combination with azithromycin hydrate led to a prompt resolution of the symptoms. Precise history-taking related to contact with rats and detection of skin eruptions suggestive of leukocytoclastic vasculitis on the extremities, especially on the feet, can be clues to Streptobacillus moniliformis infection. Familiarity with its cutaneous features is important for early diagnosis; the evidence herein may also help in understanding its underlying pathogenesis.

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A case of methotrexate-induced stomatitis and skin erosions accompanied by pancytopenia

Seiko Mitsui, Yoshio Kawakami, Takashi Katayama, Masayuki Kishida, Masaaki Usui, Tomoko Hashimoto

Nishinihon Journal of Dermatology 78 ( 4 ) 391 - 394 2016年

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