Updated on 2026/08/19

写真a

 
Qiao Lin
 
Organization
Research Institute for Interdisciplinary Science Special-Appointment Assistant Professor
Position
Special-Appointment Assistant Professor
External link

Degree

  • PhD ( Hokkaido University )

Research Interests

  • Surface Spectroscopy

  • Molecular Structure at Interfaces

  • Analytical Chemistry

  • Environmental Chemistry

  • Physical Chemistry

  • Biomembranes and Biomaterials

  • low-level ozone

  • nonlinear spectroscopy

Research Areas

  • Nanotechnology/Materials / Green sustainable chemistry and environmental chemistry

  • Nanotechnology/Materials / Fundamental physical chemistry

  • Environmental Science/Agriculture Science / Chemical substance influence on environment  / ozone

  • Natural Science / Biophysics, chemical physics and soft matter physics

  • Life Science / Metabolism and endocrinology  / 脂質代謝

  • Life Science / Nutrition science and health science  / 脂肪 / 脂質

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Education

  • Hokkaido University   大学院環境科学院  

    2012.4 - 2015.3

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Research History

  • Okayama University   Research Institute for Interdisciplinary Science   Appointed Asistant Professor

    2024.4

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  • Hokkaido University   Research Institute for Electronic Science   Guest Researcher

    2024.4

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  • Hokkaido University   Research Institute for Electronic Science   postdoctoral fellow

    2022.10 - 2024.3

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  • Faculty of Health Science, Hokkaido University   Asistant Professor

    2018.3 - 2022.3

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  • Research Institute for Electronic Science, Hokkaido University   Postdoctoral Researcher

    2017.6 - 2018.2

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  • Institute for Catalysis, Hokkaido University   Postdoctoral Researcher

    2015.11 - 2017.3

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  • Catalysis Research Center, Hokkaido University   Postdoctoral Researcher

    2015.4 - 2015.10

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Papers

  • Coexistence of Metal and Dielectric Resonance Modes in a Single Nanostructure of a Hyperbolic Material Reviewed

    Yaolong Li, Xu Shi, Yuxin Zhang, Yen-En Liu, Lin Qiao, Hong Yang, Shufeng Wang, Guowei Lyu, Yasutaka Matsuo, Xiaoyong Hu, Qihuang Gong, Hiroaki Misawa

    ACS nano   20 ( 26 )   19069 - 19077   2026.6

  • Absorption, fluorescence, and two-photon excitation ability of 5-phenyl-13-arylisoindolo[2,1-a]quinolines prepared by one-pot reaction of ring-closing metathesis and 1,3-dipolar cycloaddition

    Avena Francisco Ramon, Yuki Wada, Hirokazu Ishii, Yuki Watakabe, Motosuke Tsutsumi, Kwangkyun Jang, Kohei Otomo, Lin Qiao, Yuki Fujii, Hirofumi Tsujino, Yasuo Tsutsumi, Tomomi Nemoto, Mitsuhiro Arisawa

    Dyes and Pigments   111118 - 111118   2023.1

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    Publishing type:Research paper (scientific journal)   Publisher:Elsevier BV  

    DOI: 10.1016/j.dyepig.2023.111118

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  • Quantitative Evaluation on the Degradation Process of the Pulmonary Surfactant Monolayer When Exposed to Low-Level Ozone of Ambient Environment

    Lin Qiao, Zhen Chen, Chunji Takada, Hitoshi Chiba, Ken-ichi Inoue, Shu-Ping Hui, Shen Ye

    Analytical Chemistry   2022.5

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    Publishing type:Research paper (scientific journal)   Publisher:American Chemical Society (ACS)  

    File: Qiao-2022-Quantitative Evaluation on the Degra.pdf

    DOI: 10.1021/acs.analchem.2c00576

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  • Absorption, Fluorescence, and Two-Photon Excitation Ability of 5-Phenylisolidolo[2,1-a]quinolines Reviewed

    Ramon Francisco Avena, Lin Qiao, Yuki Fujii, Kohei Otomo, Hirokazu Ishii, Takeyuki Suzuki, Hirofumi Tsujino, Tadayuki Uno, Yasuo Tsutsumi, Yusuke Kawashima, Tatsuya Takagi, Kenichi Murai, Tomomi Nemoto, Mitsuhiro Arisawa

    ACS Omega   2020 ( 5 )   2473 - 2479   2020.1

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    Authorship:Lead author   Publishing type:Research paper (scientific journal)   Publisher:American Chemical Society (ACS)  

    DOI: 10.1021/acsomega.9b04070

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  • Surface-Restructuring Differences between Polyrotaxanes and Random Copolymers in Aqueous Environment. Reviewed

    Ge, A, Qiao, L, Seo, J.-H. H, Yui, N, Ye, S

    Langmuir   34   12463 - 12470   2018

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    Language:English   Publishing type:Research paper (scientific journal)  

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  • Theoretical and experimental examination of SFG polarization analysis at acetonitrile-water solution surfaces Reviewed

    Kengo Saito, Qiling Peng, Lin Qiao, Lin Wang, Tatsuya Joutsuka, Tatsuya Ishiyama, Shen Ye, Akihiro Morita

    PHYSICAL CHEMISTRY CHEMICAL PHYSICS   19 ( 13 )   8941 - 8961   2017.4

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c6cp08856b

    Web of Science

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  • Salt Effects on Surface Structures of Polyelectrolyte Multilayers (PEMs) Investigated by Vibrational Sum Frequency Generation (SFG) Spectroscopy Reviewed

    Aimin Ge, Michiya Matsusaki, Lin Qiao, Mitsuru Akashi, Shen Ye

    Langmuir   32 ( 16 )   3803 - 3810   2016.5

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:American Chemical Society  

    DOI: 10.1021/acs.langmuir.5b04765

    Scopus

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  • Oxidative Degradation of the Monolayer of 1-Palmitoyl-2-Oleoyl-sn-Glycero-3-Phosphocholine (POPC) in Low-Level Ozone Reviewed

    Lin Qiao, Aimin Ge, Yimin Lang, Shen Ye

    JOURNAL OF PHYSICAL CHEMISTRY B   119 ( 44 )   14188 - 14199   2015.11

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    Language:English   Publishing type:Research paper (scientific journal)  

    File: 2015_J Phys Chem B_Qiao.pdf

    DOI: 10.1021/acs.jpcb.5b08985

    Web of Science

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  • Structural Reorganization and Fibrinogen Adsorption Behaviors on the Polyrotaxane Surfaces Investigated by Sum Frequency Generation Spectroscopy Reviewed

    Aimin Ge, Ji-Hun Seo, Lin Qiao, Nobuhiko Yui, Shen Ye

    ACS APPLIED MATERIALS & INTERFACES   7 ( 40 )   22709 - 22718   2015.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1021/acsami.5b07760

    Web of Science

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  • Structural Reorganization and Fibrinogen Adsorption Behaviors on the Polyrotaxane Surfaces Investigated by Sum Frequency Generation Spectroscopy. Reviewed

    Aimin Ge, Ji-Hun Seo, Lin Qiao, Nobuhiko Yui, Shen Ye

    ACS Applied Materials & Interfaces   7 ( 40 )   22709 - 22718   2015.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    Polyrotaxanes, such as supramolecular assemblies with methylated α-cyclodextrins (α-CDs) as host molecules noncovalently threaded on the linear polymer backbone, are promising materials for biomedical applications because they allow adsorbed proteins possessing a high surface flexibility as well as control of the cellular morphology and adhesion. To provide a general design principle for biomedical materials, we examined the surface reorganization behaviors and adsorption conformations of fibrinogen on the polyrotaxane surfaces with comparison to several random copolymers by sum frequency generation (SFG) vibrational spectroscopy. We showed that the polyrotaxane (OMe-PRX-PMB) with methylated α-CDs as the host molecule exhibited unique surface structures in an aqueous environment. The hydrophobic interaction between the methoxy groups of the methylated α-CD molecules and methyl groups of the n-butyl methacrylate (BMA) side chains may dominate the surface restructuring behavior of the OMe-PRX-PMB. The orientation analysis revealed that the orientation of the fibrinogen adsorbed on the OMe-PRX-PMB surface is close to a single distribution, which is different from the adsorption be

    DOI: 10.1021/acsami.5b07760

    PubMed

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  • Molecular orientation of organic thin films on dielectric solid substrates: a phase-sensitive vibrational SFG study Reviewed

    Aimin Ge, Qiling Peng, Lin Qiao, Nageshwar R. Yepuri, Tamim A. Darwish, Michiya Matsusaki, Mitsuru Akashi, Shen Ye

    PHYSICAL CHEMISTRY CHEMICAL PHYSICS   17 ( 27 )   18072 - 18078   2015

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1039/c5cp02702k

    Web of Science

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  • Interfacial Structure of Soft Matter Probed by SFG Spectroscopy Reviewed

    Shen Ye, Yujin Tong, Aimin Ge, Lin Qiao, Paul B. Davies

    CHEMICAL RECORD   14 ( 5 )   791 - 805   2014.10

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    Language:English   Publishing type:Research paper (scientific journal)  

    DOI: 10.1002/tcr.201402039

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  • Structure and stability studies of mixed monolayers of saturated and unsaturated phospholipids under low-level ozone Reviewed

    Lin Qiao, Aimin Ge, Masatoshi Osawa, Shen Ye

    Physical Chemistry Chemical Physics   15 ( 41 )   17775 - 17785   2013.11

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MISC

  • 質量分析を用いる肺サーファクタントリン脂質膜に対する環境濃度オゾンの影響に関する研究(Study on the Lipid Monolayer of Lung Surfactant in Low-level Ozone by LC/MS)

    喬 琳, 陳 震, 高田 俊智, 千葉 仁志, 叶 深, 惠 淑萍

    JSBMS Letters   44 ( Suppl. )   101 - 101   2019.8

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    Language:English   Publisher:(一社)日本医用マススペクトル学会  

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  • 環境濃度オゾンによる肺サーファクタントリン脂質膜の酸化に関する研究

    喬 琳, 陳 震, 高田 俊智, 千葉 仁志, 叶 深, 惠 淑萍

    脂質生化学研究   61   224 - 224   2019.6

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    Language:English   Publisher:日本脂質生化学会  

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  • 環境濃度オゾンによる肺サーファクタントリン脂質膜の酸化に関する研究

    喬 琳, 陳 震, 高田 俊智, 千葉 仁志, 叶 深, 惠 淑萍

    脂質生化学研究   61   224 - 224   2019.6

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    Language:English   Publisher:日本脂質生化学会  

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  • Study on the Oxidation of the Unsaturated Phospholipid Monolayer in Low-level Ozone

    QIAO Lin, CHEN Zhen, TAKADA Shunchi, WU Yue, YE Shen, CHIBA Hitoshi, CHIBA Hitoshi, HUI Shu‐Ping

    JSBMS Letters   43 ( Supplement )   151   2018.8

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    Language:English  

    J-GLOBAL

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  • 混合単分子膜の低濃度オゾンによる酸化に及ぼすコレステロール添加の影響

    渡部 勇樹, 喬 琳, 陳 震, 高田 俊智, 呉 げつ, 叶 深, 千葉 仁志, 惠 淑萍

    JSBMS Letters   43 ( Suppl. )   153 - 153   2018.8

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    Language:Japanese   Publisher:(一社)日本医用マススペクトル学会  

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  • 環境濃度オゾンによるHepG2細胞の酸化に関する研究(Study on the Oxidation of Ambient-level Ozone on HepG2 Cells)

    朱 子健, 喬 琳, 陳 震, 呉 げつ, 千葉 仁志, 惠 淑萍

    JSBMS Letters   43 ( Suppl. )   152 - 152   2018.8

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    Language:English   Publisher:(一社)日本医用マススペクトル学会  

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Presentations

  • オゾンによる肺サーファクタントの 構造と安定性への影響

    喬 琳

    第29回臨床化学会北海道支部会  2019.10.19 

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    Presentation type:Oral presentation (general)  

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  • 質量分析を用いる肺サーファクタントリン脂質膜に対する 環境濃度オゾンの影響に関する研究

    喬 琳

    第44回日本医用マススペクトル学会年会  2019.9.12 

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    Presentation type:Poster presentation  

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  • 環境濃度オゾンによる 肺サーファクタントリン脂質膜の酸化に関する研究

    喬 琳

    第61回 日本脂質生化学会  2019.7.4 

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    Language:English   Presentation type:Oral presentation (general)  

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Awards

  • 第44回日本医用マススペクトル学会年会若手優秀ポスター賞

    2019.9  

    喬 琳

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Research Projects

  • Study on the Influence of Environmental Concentration of Ozone on Lung and Skin Cells by Lipid Analysis

    Grant number:19K21122  2019.04 - 2020.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up  Grant-in-Aid for Research Activity Start-up

    Qiao Lin

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    Grant amount:\2990000 ( Direct expense: \2300000 、 Indirect expense:\690000 )

    Ozone, with extremely high oxidative reactivity, is a common environmental toxicant to the individuals. The respiratory airways and skin tissues are two major organs most directly exposed to this oxidant pollutants. Ozone is hypothesized to initiate intracellular oxidative stress and induce the inflammation in the lung and skin through the formation of oxidized lipids. In the present study, in order to study the lipid oxidation during the exposure to the low-level ozone, which is similar to the average concentration observed in ambient air, we successfully establish a novel and sensitive lipid analysis method by high performance liquid chromatography combined with high-resolution orbitrap tandem mass spectrometry. The ozonized lipids of the lung surfactants and the lung cells were successfully identified and quantified. It helps us to further understand the reaction mechanism between the lipid in the lung and the low-level ozone in the air at a molecular level.

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  • 極低濃度オゾン雰囲気における疑似細胞膜の構造評価

    2014.06

    公益財団法人北海道大学クラーク記念財団 博士後期課程在学生研究助成 

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