2021/12/16 更新

写真a

ハナモト カツミ
花元 克巳
HANAMOTO Katsumi
所属
保健学域 准教授
職名
准教授
外部リンク

学位

  • 修士(理学) ( 立命館大学 )

  • 博士(理学) ( 立命館大学 )

研究キーワード

  • quantum beam physics

  • 材料科学

  • materials science

  • 量子ビーム物理学

研究分野

  • エネルギー / 量子ビーム科学

経歴

  • 岡山大学   大学院保健学研究科   准教授

    2021年10月 - 現在

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    国名:日本国

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所属学協会

委員歴

  • 岡山大学岡山大学自然生命科学研究支援センター 光・放射線情報解析部門鹿田施設   運営会議委員  

    2021年4月 - 現在   

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  • 岡山大学   職員代表委員会委員  

    2020年4月 - 2021年3月   

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  • 岡山大学大学院保健学研究科   教務委員  

    2016年4月 - 現在   

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  • 岡山大学自然生命科学研究支援センター光・放射線情報解部門鹿田施設   放射線障害防止委員会委員  

    2010年4月 - 現在   

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論文

  • Radon inhalation decreases DNA damage induced by oxidative stress in mouse organs via the activation of antioxidative functions. 国際誌

    Takahiro Kataoka, Hina Shuto, Shota Naoe, Junki Yano, Norie Kanzaki, Akihiro Sakoda, Hiroshi Tanaka, Katsumi Hanamoto, Fumihiro Mitsunobu, Hiroaki Terato, Kiyonori Yamaoka

    Journal of radiation research   2021年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    Radon inhalation decreases the level of lipid peroxide (LPO); this is attributed to the activation of antioxidative functions. This activation contributes to the beneficial effects of radon therapy, but there are no studies on the risks of radon therapy, such as DNA damage. We evaluated the effect of radon inhalation on DNA damage caused by oxidative stress and explored the underlying mechanisms. Mice were exposed to radon inhalation at concentrations of 2 or 20 kBq/m3 (for one, three, or 10 days). The 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels decreased in the brains of mice that inhaled 20 kBq/m3 radon for three days and in the kidneys of mice that inhaled 2 or 20 kBq/m3 radon for one, three or 10 days. The 8-OHdG levels in the small intestine decreased by approximately 20-40% (2 kBq/m3 for three days or 20 kBq/m3 for one, three or 10 days), but there were no significant differences in the 8-OHdG levels between mice that inhaled a sham treatment and those that inhaled radon. There was no significant change in the levels of 8-oxoguanine DNA glycosylase, which plays an important role in DNA repair. However, the level of Mn-superoxide dismutase (SOD) increased by 15-60% and 15-45% in the small intestine and kidney, respectively, following radon inhalation. These results suggest that Mn-SOD probably plays an important role in the inhibition of oxidative DNA damage.

    DOI: 10.1093/jrr/rrab069

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  • The Effects of Low-Dose-Rate γ-irradiation on Forced Swim Test-Induced Immobility and Oxidative Stress in Mice.

    Tetsuya Nakada, Takahiro Kataoka, Takaharu Nomura, Hina Shuto, Junki Yano, Shota Naoe, Katsumi Hanamoto, Kiyonori Yamaoka

    Acta medica Okayama   75 ( 2 )   169 - 175   2021年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    The forced swim test (FST) induces immobility in mice. Low-dose (high-dose-rate) X-irradiation inhibits FSTinduced immobility in mice due to its antioxidative function. We evaluated the effects of low-dose γ-irradiation at a low-dose-rate on the FST-induced depletion of antioxidants in mouse organs. Mice received whole-body low-dose-rate (0.6 or 3.0 mGy/h) of low-dose γ-irradiation for 1 week, followed by daily FSTs (5 days). The immobility rate on day 2 compared to day 1 was significantly lower in the 3.0 mGy/h irradiated mice than in sham irradiated mice. The FST significantly decreased the catalase (CAT) activity and total glutathione (t-GSH) content in the brain and kidney, respectively. The superoxide dismutase (SOD) activity and t-GSH content in the liver of the 3.0 mGy/h irradiated mice were significantly lower than those of the non-FST-treated mice. The CAT activity in the lungs of mice exposed to 3.0 mGy/h γ-irradiation was higher than that of non-FST treated mice and mice treated with FST. However, no significant differences were observed in the levels of these antioxidant markers between the sham and irradiated groups except for the CAT activity in lungs. These findings suggest that the effects of low-dose-rate and low-dose γ-irradiation on FST are highly organ-dependent.

    DOI: 10.18926/AMO/61896

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  • Evaluation of the redox state in mouse organs following radon inhalation

    Takahiro Kataoka, Norie Kanzaki, Akihiro Sakoda, Hina Shuto, Junki Yano, Shota Naoe, Hiroshi Tanaka, Katsumi Hanamoto, Hiroaki Terato, Fumihiro Mitsunobu, Kiyonori Yamaoka

    Journal of radiation research   62 ( 2 )   206 - 216   2021年3月

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    掲載種別:研究論文(学術雑誌)  

    Radon inhalation activates antioxidative functions in mouse organs, thereby contributing to inhibition of oxidative stress-induced damage. However, the specific redox state of each organ after radon inhalation has not been reported. Therefore, in this study, we evaluated the redox state of various organs in mice following radon inhalation at concentrations of 2 or 20 kBq/m3 for 1, 3 or 10 days. Scatter plots were used to evaluate the relationship between antioxidative function and oxidative stress by principal component analysis (PCA) of data from control mice subjected to sham inhalation. The results of principal component (PC) 1 showed that the liver and kidney had high antioxidant capacity; the results of PC2 showed that the brain, pancreas and stomach had low antioxidant capacities and low lipid peroxide (LPO) content, whereas the lungs, heart, small intestine and large intestine had high LPO content but low antioxidant capacities. Furthermore, using the PCA of each obtained cluster, we observed altered correlation coefficients related to glutathione, hydrogen peroxide and LPO for all groups following radon inhalation. Correlation coefficients related to superoxide dismutase in organs with a low antioxidant capacity were also changed. These findings suggested that radon inhalation could alter the redox state in organs; however, its characteristics were dependent on the total antioxidant capacity of the organs as well as the radon concentration and inhalation time. The insights obtained from this study could be useful for developing therapeutic strategies targeting individual organs.

    DOI: 10.1093/jrr/rraa129

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  • X-Irradiation at 0.5 Gy after the forced swim test reduces forced swimming-induced immobility in mice

    Takahiro Kataoka, Hina Shuto, Junki Yano, Shota Naoe, Tsuyoshi Ishida, Tetsuya Nakada, Keiko Yamato, Katsumi Hanamoto, Takaharu Nomura, Kiyonori Yamaoka

    Journal of Radiation Research   61 ( 4 )   517 - 523   2020年7月

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    掲載種別:研究論文(学術雑誌)  

    The forcedswimtest (FST)is a screeningmodel forantidepressantactivity; it causes immobilityand inducesoxidative stress. We previously reported that radon inhalation has antidepressant-like effects in mice potentially through the activation of antioxidative functions upon radon inhalation. This study aimed to investigate the effect of prior and post low-dose X-irradiation (0.1, 0.5, 1.0 and 2.0 Gy) on FST-induced immobility and oxidative stress in the mouse brain, and the differences, if any, between the two.Mice received X-irradiation before or after the FST repeatedly for 5 days. In the post-FST-irradiated group, an additional FST was conducted 4 h after the last irradiation.Consequently, animals receiving priorX-irradiation (0.1Gy) had better mobility outcomes than sham-irradiatedmice; however, their levels of lipid peroxide (LPO), an oxidative stressmarker, remained unchanged.However, animals that received post- FST X-irradiation (0.5 Gy) had better mobility outcomes and their LPO levels were significantly lower than those of the sham-irradiated mice. The present results indicate that 0.5 Gy X-irradiation after FST inhibits FST-induced immobility and oxidative stress in mice.

    DOI: 10.1093/jrr/rraa022

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  • マウス脳における低線量照射による抗酸化機能の亢進とアスコルビン酸投与併用による複合効果の基礎的検討 査読

    片岡隆浩, 柚木勇人, 神﨑訓枝, 笹岡香織, 小橋佑介, 石田 毅, 花元克巳, 山岡聖典

    69 ( 2 )   45 - 53   2020年2月

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  • Pressure dependence of X-rays produced by an LiTaO3 single crystal over a wide range of pressure

    Katsumi Hanamoto, Takahiro Kataoka, Kiyonori Yamaoka

    Applied Radiation and Isotopes   135   40 - 42   2018年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:Elsevier Ltd  

    The energy spectra of X-rays produced by an LiTaO3 single crystal have been measured at the pressures of 8 × 10−4−4 Pa. The energy spectra showed that the endpoint energy steadily increased with decrease of pressure at 2–4 Pa and gradually decreased with decrease of pressure at 0.1–2 Pa, and became almost constant below 0.1 Pa. The amount of X-rays steadily increased with decrease of pressure at 2–4 Pa and almost saturated below 0.5 Pa. The change of X-rays produced by the LiTaO3 single crystal was compared with the previous works and discussed in relation to the distance between the crystal surface and the target.

    DOI: 10.1016/j.apradiso.2018.01.019

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  • Pressure dependence of X-rays produced by an LiTaO3 single crystal at the pressures of 1-20 Pa

    Katsumi Hanamoto, Takahiro Kataoka, Kiyonori Yamaoka

    APPLIED RADIATION AND ISOTOPES   116   134 - 137   2016年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    The energy spectra of X-rays produced by an LiTaO3 single crystal have been measured at pressures of 1-20 Pa. The energy spectra showed that the endpoint energy and the amount of X-rays gradually increased with the decrease of pressure at 5-8 Pa and abruptly increased around 4 Pa and below. A maximum endpoint energy of 70 keV was obtained using the LiTaO3 single crystal with 5 mm thickness at a pressure of 3 Pa. The change of X-rays produced by the LiTaO(3)single crystal was discussed in relation to the breakdown potential at the pressures. (C) 2016 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.apradiso.2016.08.003

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  • Activation of Antioxidative Functions by Radon Inhalation Enhances the Mitigation Effects of Pregabalin on Chronic Constriction Injury-Induced Neuropathic Pain in Mice

    Takahiro Kataoka, Shunsuke Horie, Reo Etani, Norie Kanzaki, Kaori Sasaoka, Yusuke Kobashi, Katsumi Hanamoto, Kiyonori Yamaoka

    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY   2016   2016年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:HINDAWI LTD  

    Radon inhalation brings pain relief for chronic constriction injury- (CCI-) induced neuropathic pain in mice due to the activation of antioxidative functions, which is different from the mechanism of the pregabalin effect. In this study, we assessed whether a combination of radon inhalation and pregabalin administration is more effective against neuropathic pain than radon or pregabalin only. Mice were treated with inhaled radon at a concentration of 1,000 Bq/m(3) for 24 hours and pregabalin administration after CCI surgery. In mice treated with pregabalin at a dose of 3 mg/kg weight, the 50% paw withdrawal threshold of mice treated with pregabalin or radon and pregabalin was significantly increased, suggesting pain relief. The therapeutic effects of radon inhalation or the combined effects of radon and pregabalin (3 mg/kg weight) were almost equivalent to treatment with pregabalin at a dose of 1.4 mg/kg weight or 4.1 mg/kg weight, respectively. Radon inhalation and the combination of radon and pregabalin increased antioxidant associated substances in the paw. The antioxidant substances increased much more in radon inhalation than in pregabalin administration. These findings suggested that the activation of antioxidative functions by radon inhalation enhances the pain relief of pregabalin and that this combined effect is probably an additive effect.

    DOI: 10.1155/2016/9853692

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  • Evaluating the protective effects of radon inhalation or ascorbic acid treatment after transient global cerebral ischemic injury in gerbils

    Takahiro Kataoka, Reo Etani, Norie Kanzaki, Kaori Sasaoka, Yusuke Kobashi, Katsumi Hanamoto, Takehito Taguchi, Kiyonori Yamaoka

    JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY   53 ( 11 )   1681 - 1685   2016年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:TAYLOR & FRANCIS LTD  

    In this study, we compared the protective effects of radon inhalation and ascorbic acid administration on transient global cerebral ischemic injury in gerbils. Gerbils were treated with radon inhalation (2000 Bq/m(3), 24 hours) or ascorbic acid (100, 300, or 500mg/kg body weight). Then, transient global cerebral ischemia was induced by bilateral occlusion of the common carotid artery. Results showed that the number of damaged neurons was significantly increased in gerbils that underwent ischemia compared with that in control gerbils. However, the number of damaged neurons in gerbils treated with radon or 500mg/kg of ascorbic acid before ischemia was significantly lower than gerbils who were subjected to ischemia without any pretreatment, and the protective effects of radon inhalation were similar to the effects of administering 500mg/kg ascorbic acid. The levels of superoxide dismutase (SOD) and total glutathione (t-GSH) in brain tissue were increased to a similar extent by pretreatment with radon inhalation or 500mg/kg of ascorbic acid. These findings suggested that radon inhalation has a protective antioxidative effect against transient global cerebral ischemic injury similar to 500mg/kg ascorbic acid treatment.

    DOI: 10.1080/00223131.2016.1198731

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  • Effects of cream containing ultralow volume radionuclides on carrageenan-induced inflammatory paw edema in mice 査読

    Takahiro Kataoka, Yuji Takata, Reo Etani, Yuichi Nishiyama, Atsushi Kawabe, Katsumi Hanamoto, Takehito Taguchi, Kiyonori Yamaoka

    Biochemistry & Physiology   3 ( 2 )   1 - 5   2014年

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  • Radioactivity of Pb-210 in Japanese cigarettes and radiation dose from smoking inhalation

    A. Sakoda, K. Fukao, A. Kawabe, T. Kataoka, K. Hanamoto, K. Yamaoka

    RADIATION PROTECTION DOSIMETRY   150 ( 1 )   109 - 113   2012年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:OXFORD UNIV PRESS  

    It is well known that cigarette tobaccos contain naturally occurring radioactive nuclides such as Pb-210 and Po-210. In many countries, the radioactivity of tobaccos has been measured to estimate the effective dose from smoking inhalation. The present study covered 24 cigarette brands including the top 20 of sales in Japan between April 2008 and March 2009. The activity concentrations of Pb-210 were measured by gamma-ray spectrometry, and then those of its progeny (Po-210) were evaluated assuming the radioactive equilibrium between the two nuclides. Their concentrations were in the range of 214 mBq cigarette(1) with an arithmetic mean of 83 mBq cigarette(1). The annual committed effective doses were also calculated, based on the scenario that a smoker consumes 20 cigarettes a day. The average doses from Pb-210 and Po-210 inhalations were 229 and 6827 Sv y(1), respectively.

    DOI: 10.1093/rpd/ncr364

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  • Pressure dependence of X-rays produced by an LiTaO3 single crystal at low pressures

    Katsumi Hanamoto, Atsushi Kawabe, Akihiro Sakoda, Takahiro Kataoka, Mari Okada, Kiyonori Yamaoka

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT   669   66 - 69   2012年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    The energy spectra of X-rays produced by an LiTaO3 single crystal have been measured at pressures of 5-50 Pa. The energy spectra showed that the amount of X-rays increased exponentially and the endpoint energy of the spectra increased linearly with the decrease of pressure at pressures of 10-25 Pa. A maximum endpoint energy of about 22 key was obtained using an LiTaO3 single crystal with 0.5 mm thickness at the pressure of 10 Pa. The maximum energy produced by the present experimental setup was estimated assuming that the LiTaO3 single crystal forms a parallel-plate capacitor. The estimated energy reasonably agreed with the energy obtained. The pressure dependence of the endpoint energy was discussed in relation to the breakdown potential at low pressures. (C) 2011 Elsevier B.V. All rights reserved.

    DOI: 10.1016/j.nima.2011.12.028

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  • ラドン吸入がペットの健康に及ぼす効果に関する基礎的検討

    片岡 隆浩, 徳永力三, 迫田晃弘, 川辺 睦, 花元克巳, 山岡聖典

    RAIDOISOTOPES   61 ( 1 )   1 - 8   2012年

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.3769/radioisotopes.61.1

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  • Comparative Study on the Inhibitory Effects of alpha-Tocopherol and Radon on Carbon Tetrachloride-Induced Renal Damage

    Takahiro Kataoka, Keiko Yamato, Yuichi Nishiyama, Yuji Morii, Reo Etani, Yuji Takata, Katsumi Hanamoto, Atsuishi Kawabe, Akihiro Sakoda, Yuu Ishimori, Takehito Taguchi, Kiyonori Yamaoka

    RENAL FAILURE   34 ( 9 )   1181 - 1187   2012年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:TAYLOR & FRANCIS LTD  

    Since the 2011 nuclear accident in Fukushima, the effects of low-dose irradiation, especially internal exposure, are at the forefront of everyone's attention. However, low-dose radiation induced various stimulating effects such as activation of antioxidative and immune functions. In this study, we attempted to evaluate the quantitative effects of the activation of antioxidative activities in kidney induced by radon inhalation on carbon tetrachloride (CCl4)-induced renal damage. Mice were subjected to intraperitoneal (i.p.) injection of CCl4 after inhaling approximately 1000 or 2000 Bq/m(3) radon for 24 h, or immediately after i.p. injection of alpha-tocopherol (100, 300, or 500 mg/kg bodyweight). In case of renal function, radon inhalation at a concentration of 2000 Bq/m(3) has the inhibitory effects similar to alpha-tocopherol treatment at a dose of 300-500 mg/kg bodyweight. The activities of superoxide dismutase and catalase in kidneys were significantly higher in mice exposed to radon as compared to mice treated with CCl4 alone. These findings suggest that radon inhalation has an antioxidative effect against CCl4-induced renal damage similar to the antioxidative effects of alpha-tocopherol due to induction of antioxidative functions.

    DOI: 10.3109/0886022X.2012.717496

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  • Studies on possibility for alleviation of lifestyle diseases by low-dose irradiation or radon inhalation. 査読

    Kataoka T, Sakoda A, Yoshimoto M, Nakagawa S, Toyota T, Nishiyama Y, Yamato K, Ishimori Y, Kawabe A, Hanamoto K, Taguchi T, Yamaoka K

    Radiation protection dosimetry   146 ( 1-3 )   360 - 363   2011年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1093/rpd/ncr189

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  • A comparative study on effect of continuous radon inhalation on several-time acute alcohol-induced oxidative damages of liver and brain in mouse

    Takahiro Kataoka, Akihiro Sakoda, Masaaki Yoshimoto, Teruaki Toyota, Yuki Yamamoto, Yuu Ishimori, Katsumi Hanamoto, Atsushi Kawabe, Fumihiro Mitsunobu, Kiyonori Yamaoka

    Radiation Safety Management   10 ( 1 )   1 - 7   2011年

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    掲載種別:研究論文(学術雑誌)   出版者・発行元:Japanese Society of Radiation Safety Management  

    DOI: 10.12950/rsm.10.1

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  • Erratum to Differences of natural radioactivity and radon emanation fraction between constituent minerals of rock or soil [Appl. Radiat. Isot. 68, 6, (2010), 1180-1184] 査読

    Akihiro Sakoda, Yuichi Nishiyama, Katsumi Hanamoto, Yuu Ishimori, Yuki Yamamoto, Takahiro Kataoka, Atsushi Kawabe, Kiyonori Yamaoka

    Applied Radiation and Isotopes   68 ( 12 )   2452   2010年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    DOI: 10.1016/j.apradiso.2010.04.025

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  • Applicability and performance of an imaging plate at subzero temperatures 査読

    Akihiro Sakoda, Yuu Ishimori, Katsumi Hanamoto, Atsushi Kawabe, Takahiro Kataoka, Tomohiro Nagamatsu, Kiyonori Yamaoka

    APPLIED RADIATION AND ISOTOPES   68 ( 10 )   2013 - 2015   2010年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    The performance of imaging plates (IPs) has not been studied at temperatures lower than 0 degrees C. In the present study, an IP was irradiated with gamma rays emitted from the mineral monazite at temperatures between -80 and 30 degrees C to determine its fundamental properties. The IP response as a function of irradiation time was found to be linear, suggesting that the IP works properly at low temperatures. Fading, an effect which should be considered at temperatures of more than 0 degrees C, was not observed at -30 and 80 degrees C. Furthermore, the fading-corrected PSL value of the IP irradiated at 80 degrees C was lower than at other temperatures (30.5 and -30 degrees C). This can be explained by thermostimulated luminescence (TSL). Since the only intensive TSL peak in the temperature range from -80 to 30 degrees C is present at about -43 degrees C, some of the electrons trapped at F centers recombine with holes through the process of TSL before the stored radiation image is read out at room temperature. This finding suggests that the apparent sensitivity of the IP is lower at -80 degrees C although it is similar to sensitivities between -30 and 30 degrees C. This low sensitivity should be corrected to perform quantitative measurements. (C) 2010 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.apradiso.2010.03.020

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  • Physiologically Based Pharmacokinetic Modeling of Inhaled Radon to Calculate Absorbed Doses in Mice, Rats, and Humans 査読

    Akihiro Sakoda, Yuu Ishimori, Atsushi Kawabe, Takahiro Kataoka, Katsumi Hanamoto, Kiyonori Yamaoka

    JOURNAL OF NUCLEAR SCIENCE AND TECHNOLOGY   47 ( 8 )   731 - 738   2010年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:TAYLOR & FRANCIS LTD  

    This is the first report to provide radiation doses, arising from inhalation of radon itself, in mice and rats. To quantify absorbed doses to organs and tissues in mice, rats, and humans, we computed the behavior of inhaled radon in their bodies on the basis of a physiologically based pharmacokinetic (PBPK) model. It was assumed that radon dissolved in blood entering the gas exchange compartment is transported to any tissue by the blood circulation to be instantaneously distributed according to a tissue/blood partition coefficient. The calculated concentrations of radon in the adipose tissue and red bone marrow following its inhalation were much higher than those in the others, because of the higher partition coefficients. Compared with a previous experimental data for rats and model calculation for humans, the present calculation was proved to be valid. Absorbed dose rates to organs and tissues were estimated to be within the range of 0.04-1.4 nGy (Bq m(-3))(-1) day(-1) for all the species. Although the dose rates are not so high, it may be better to pay attention to the dose to the red bone marrow from the perspective of radiation protection. For more accurate dose assessment, it is necessary to update tissue/blood partition coefficients of radon that strongly govern the result of the PBPK modeling.

    DOI: 10.1080/18811248.2010.9711649

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  • Differences of natural radioactivity and radon emanation fraction among constituent minerals of rock or soil 査読

    Akihiro Sakoda, Yuichi Nishiyama, Katsumi Hanamoto, Yuu Ishimori, Yuki Yamamoto, Takahiro Kataoka, Atsushi Kawabe, Kiyonori Yamaoka

    APPLIED RADIATION AND ISOTOPES   68 ( 6 )   1180 - 1184   2010年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    We examined differences in the radioactive characteristics among the main minerals forming granite materials. Using a non-toxic high-density agent, minerals were separated from rock (granite-gneiss) and soil (weathered granite) samples. The natural radioactivity ((238)U and (226)Ra) and radon emanation fraction of the minerals were then studied by gamma-ray spectrometry. The radon emanation fractions (27-43%) of the minerals from the soil were much higher than those (0.6-4.6%) of the rock minerals. Additionally, the emanation fractions differed greatly among the minerals separated from both the bulk rock and soil. These results were discussed in terms of the differences of surface area and radium distribution in the mineral grains. It was noticeable that a higher emanation fraction than expected for quartz was commonly observed in the rock and soil samples. We then estimated the contribution of each constituent mineral to the total radon exhalation from the bulk samples. The result depended not only on the radon emanation fraction, but also on the (226)Ra activity and the mineral content. Furthermore, using the obtained data, we also discussed the effect of grain size on radon emanation and why this has been reported to vary markedly in previous studies. (C) 2010 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.apradiso.2009.12.036

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  • First model of the effect of grain size on radon emanation 査読

    Akihiro Sakoda, Katsumi Hanamoto, Yuu Ishimori, Takahiro Kataoka, Atsushi Kawabe, Kiyonori Yamaoka

    APPLIED RADIATION AND ISOTOPES   68 ( 6 )   1169 - 1172   2010年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    The present model represents an improvement on previous models of radon emanation from soil by incorporating soil grain size in addition to moisture. Monte Carlo simulation was employed in the calculation since it was difficult to mathematically express the radon emanation fraction for the present soil model. Grain size is one of the most important factors in describing the properties of soil. Grain size was demonstrated to affect the radon emanation fraction, depending on moisture content. Although the emanation fraction is generally considered to be proportional to grain size, the result of the model calculation suggested that the effect of grain size is not so simple. This study should serve as an initial step toward improving the modeling of this radon emanation. (C) 2010 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.apradiso.2009.11.070

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  • Experimental and modeling studies of grain size and moisture content effects on radon emanation 査読

    Akihiro Sakoda, Yuu Ishimori, Katsumi Hanamoto, Takahiro Kataoka, Atsushi Kawabe, Kiyonori Yamaoka

    RADIATION MEASUREMENTS   45 ( 2 )   204 - 210   2010年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    Some models have already been developed to explain the effect of moisture content on the radon emanation fraction of soil. For this purpose, "microscopic" soil models, which are easy to deal with mathematically but cannot take grain size into consideration, have been designed. These previous models consist basically of two opposite grain surfaces and pores between the grains. In the present study, in order to study the effect of not only moisture content but also grain size, we present a simple modeling approach based on two "macroscopic" soil models: (1) a single-grain model and (2) a multiple-grain model. The latter model represents a configuration of spherical grains packed in a simple cubic structure. Based on these soil models and general assumptions, the radon emanation fraction was calculated as a function of grain size or moisture content by Monte Carlo simulation. The results for the multiple-grain model show that the radon emanation fraction is markedly increased with grain sizes ranging from 10 to 100 inn and reaches a constant value of 50% when moisture content is 0% and the radium is uniformly distributed on the grain surface. Moreover, a drastic increase is seen at smaller grain sizes with increasing moisture content. From these results, we concluded that the calculation of radon emanation depends greatly on the pore size between a Ra-bearing grain and a neighboring grain. The validity of the model was also evaluated by comparison to experimental data. (C) 2010 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.radmeas.2010.01.010

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  • 小動物病院におけるX線撮影に伴う放射線診療従事者の実効線量評価 査読

    川辺 睦, 山田 一孝, 花元 克巳, 迫田 晃弘, 片岡 隆浩, 山岡 聖典

    動物臨床医学   19 ( 4 )   113 - 117   2010年

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  • Radioactivity and radon emanation fraction of the granites sampled at Misasa and Badgastein

    Akihiro Sakoda, Katsumi Hanamoto, Yuu Ishimori, Tomohiro Nagamatsu, Kiyonori Yamaoka

    APPLIED RADIATION AND ISOTOPES   66 ( 5 )   648 - 652   2008年5月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    The chemical composition was analyzed and the radioactivity, radon exhalation rate and emanation fraction were measured to investigate the characteristics of the granites sampled at Misasa and Badgastein, world famous for radon therapy. The Misasa granite was probably composed of quartz, albite and microcline. The Badgastein granite was probably composed of quartz and muscovite. The radon exhalation rates and emanation fractions of the Misasa granite were much higher than those of the Badgastein granite, regardless of the (226)Ra activity concentrations. (C) 2007 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.apradiso.2007.11.015

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  • 小型MRI装置の作製 エコー信号のフィッティングによる再構成画像の鮮鋭化

    花元 克巳, 加藤 博和, 澁谷 光一, 川崎 祥二, 黒田 昌宏, 金澤 右, 岸 幹二, 柳 文修, 本多 康聡, 大野 誠一郎, 門久 繁文, 高橋 則雄, 青木 雅昭

    Radiation Medicine   26 ( Suppl.I )   59 - 59   2008年4月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • MRI装置の作製

    加藤 博和, 花元 克巳, 山本 尚武, 黒田 昌宏, 金澤 右, 本多 康聡, 柳 文修, 高橋 則雄, 岸 幹二, 大塚 裕太, 井上 皓介, 真鍋 英朗, 宮武 匡義, 青木 雅昭

    Radiation Medicine   26 ( Suppl.I )   58 - 58   2008年4月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • Effects of some physical conditions on leaching rate of radon from radioactive minerals originating from some hot springs

    Akihiro Sakoda, Katsumi Hanamoto, Yuu Ishimori, Tomohiro Nagamatsu, Kiyonori Yamaoka

    RADIATION MEASUREMENTS   43 ( 1 )   106 - 110   2008年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    In order to determine the best physical conditions for leaching more radon from minerals into water, we measured the leaching rate of radon from radioactive minerals under the conditions of some different grain sizes and water temperatures. Water temperature affected the leaching rate of radon although the grain size did not significantly affect it. Furthermore, we proposed ultrasonic irradiation to the mixture of a mineral and water as the method of leaching more radon. Ultrasonic irradiation was efficient to leach more radon from the mineral soaked in water because of ultrasonic cavitation. (C) 2007 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.radmeas.2007.07.009

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  • ラドン吸入試作装置によるマウス諸臓器中の抗酸化機能の亢進に関する研究

    中川慎也, 片岡隆浩, 迫田晃弘, 石森有, 花元克巳, 山岡聖典

    Radioisotopes   57 ( 4 )   241 - 245   2008年

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.3769/radioisotopes.57.241

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  • Methodological Approach for Assessment of the Radioactivity Level in Dry Solid Waste

    Tomohiro Nagamatsu, Akihiro Sakoda, Katsumi Hanamoto, Ikuo Kinno, Tadashi Hanafusa, Kiyonori Yamaoka, Toshiro Ono

    Radiation Sefety Management   7 ( 1 )   6 - 10   2008年

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.12950/rsm2002.7.6

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  • 小型MRI装置の作製 矩形ファントムの画像再構成

    加藤 博和, 花元 克巳, 澁谷 光一, 川崎 祥二, 黒田 昌宏, 金澤 右, 柳 文修, 本多 康聡, 岸 幹二, 高橋 則雄, 綾野 成記, 芝 潤, 金澤 圭剛

    Radiation Medicine   25 ( Suppl.I )   92 - 92   2007年4月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • 位相エンコーディング方向に現れる低信号アーチファクトの解析

    花元 克巳, 加藤 博和, 澁谷 光一, 川崎 祥二, 黒田 昌宏, 金澤 右, 大野 誠一郎, 門久 繁文

    Radiation Medicine   25 ( Suppl.I )   92 - 92   2007年4月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • A comparative study on the characteristics of radioactivities and negative air ions originating from the minerals in some radon hot springs

    Akihiro Sakoda, Katsumi Hanamoto, Naoto Haruki, Tomohiro Nagamatsu, Kiyonori Yamaoka

    APPLIED RADIATION AND ISOTOPES   65 ( 1 )   50 - 56   2007年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    To elucidate the characteristics of some radon hot springs, we simulated a hot spring by soaking the rocks for the radon therapy in water and measured the concentrations of radon and negative air ions in various conditions. In the results, the individual rock structure could contribute to radon leaching because the radon leaching rates were independent of the grain sizes. More negative air ions were generated by the wet rocks than by the dry rocks. (c) 2006 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.apradiso.2006.07.015

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  • 光刺激ルミネセンス線量計の低エネルギー連続X線に対するエネルギー特性

    川辺睦, 澁谷光一, 花元克巳, 小林育夫, 竹田芳弘

    保健物理   2006年

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  • Composition of MRI phantom equivalent to human tissues

    H Kato, M Kuroda, K Yoshimura, A Yoshida, K Hanamoto, S Kawasaki, K Shibuya, S Kanazawa

    MEDICAL PHYSICS   32 ( 10 )   3199 - 3208   2005年10月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:AMER ASSOC PHYSICISTS MEDICINE AMER INST PHYSICS  

    We previously developed two new MRI phantoms (called the CAG phantom and the CAGN phantom), with T1 and T2 relaxation times equivalent to those of any human tissue at 1.5 T. The conductivity of the CAGN phantom is equivalent to that of most types of human tissue in the frequency range of 1 to 130 MHz. In this paper, the relaxation times of human tissues are summarized, and the composition of the corresponding phantoms are provided in table form. The ingredients of these phantoms are carrageenan as the gelling agent, GdCl3 as a T1 modifier, a-arose as a T2 modifier, NaCl (CAGN phantom only) as a conductivity modifier, NaN3 as an antiseptic, and distilled water. The phantoms have T1 values of 202-1904 ms and T2 values of 38-423 ms when the concentrations of GdCl3 and agarose are varied from 0-140 mu mol/kg, and 0%-1.6%, respectively, and the CAGN phantom has a conductivity of 0.27-1.26 S/m when the NaCl concentration is varied from 0%-0.7%. These phantoms have sufficient strength to replicate a torso without the use of reinforcing agents, and can be cut by a knife into any shape. We anticipate the CAGN phantom to be highly useful and practical for MRI and hyperthermia-related research. (9) 2005 American Association of Physicists in Medicine.

    DOI: 10.1118/1.2047807

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  • Development of a new hybrid gel phantom using carrageenan and gellan gum for visualizing three-dimensional temperature distribution during hyperthermia and radiofrequency ablation

    M Kuroda, H Kato, K Hanamoto, K Shimamura, T Uchida, Y Wang, S Akaki, JI Asaumi, K Himei, M Takemoto, S Kanazawa, K Shibuya, S Kawasaki, Y Hiraki

    INTERNATIONAL JOURNAL OF ONCOLOGY   27 ( 1 )   175 - 184   2005年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:SPANDIDOS PUBL LTD  

    We developed a new hybrid gel phantom using carrageenan and gellan gum for the purpose of visualizing three-dimensional temperature distribution. The phantom, which contains carrageenan, gellan gum, non-ionic surface active agent, potassium chloride, n-butanol, sodium azide, and water, shows good transparency at room temperature, and has the advantage that the heated region becomes white and opaque due to segregation of the surface active agent. Carrageenan and gellan gum were added to improve the transparency and fragility of the hybrid gel. Potassium chloride was used to adjust the electrical conductivity of the gel to a range of 5-130 MHz, so that it would be equivalent to that of muscle tissue for each frequency used by electromagnetic heating devices. N-butanol was used to adjust the clouding temperature to a range between 45 and 55 degrees C. In the present study we clarified the important properties of the new phantom, and developed formulae for easy determination of the amounts of ingredients necessary for the desired clouding temperature and electric conductivity. The characteristics of this phantom are: a) a solid form to avoid convection by heat conduction; b) sufficient strength without fragility to form a torso without the use of a reinforcing agent; c) high transparency at room temperature and visualization of the heating area as a white turbidity; d) time-lapse and accurate visualization of the changing temperature area without thermal hysteresis; e) electrical properties similar to those of human tissues; f) ease of production; and g) low cost and good safety. This phantom might assist oncologists in their routine checking and study of the performance of electromagnetic heating devices for hyperthermia and radiofrequency ablation.

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  • 小型MRI装置用シーケンシャルパルスジェネレータの開発

    花元 克己, 加藤 博和, 帆足 正勝, 青山 良宏, 西 健二, 溝渕 真一, 大胡 文彦, 坂井 千尋, 田中 雅大, 馬場園 喬, 黒田 昌宏, 金澤 右

    日本医学放射線学会雑誌   65 ( 2 )   154 - 154   2005年4月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • 小型MRI装置用RFコイルの作製

    加藤 博和, 花元 克巳, 青山 良宏, 帆足 正勝, 大胡 文彦, 黒田 昌宏, 金澤 右, 溝渕 真一, 西 健二, 坂井 千尋, 田中 雅大, 馬場園 喬

    日本医学放射線学会雑誌   65 ( 2 )   155 - 155   2005年4月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • MnSOD遺伝子導入に伴うplating efficiencyの変化

    黒田 昌宏, 小松 めぐみ, 王 雅棣, 加藤 博和, 花元 克巳, 武本 充広, 姫井 健吾, 山本 泰宏, 平木 祥夫, 金澤 右

    日本医学放射線学会雑誌   65 ( 2 )   161 - 161   2005年4月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • p53遺伝子,MnSOD遺伝子導入に伴う細胞死の検討

    王 雅棣, 黒田 昌宏, 小松 めぐみ, 加藤 博和, 花元 克己, 姫井 健吾, 武本 充広, 山本 泰宏, 平木 祥夫, 金澤 右

    日本医学放射線学会雑誌   65 ( 2 )   161 - 161   2005年4月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • The elevation of p53 protein level and SOD activity in the resident blood of the Misasa radon hot spring district

    K Yamaoka, F Mitsunobu, S Kojima, M Shibakura, T Kataoka, K Hanamoto, Y Tanizaki

    JOURNAL OF RADIATION RESEARCH   46 ( 1 )   21 - 24   2005年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JAPAN RADIATION RESEARCH SOC  

    To clarify the mechanism by which radon hot springs prevent cancer or not, in this study, blood was collected from residents in the Misasa hot spring district and in a control district. The level of a representative cancer-suppressive gene, p53, and the activity of a representative antioxidant enzyme, superoxide dismutase (SOD), were analyzed as indices. The level of serum p53 protein in the males in the Misasa hot spring district was found to be 2-fold higher than that in the control district, which is a significant difference. In the females in the Misasa hot spring district, SOD activity was approximately 15% higher than that in the control district, which is also statistically significant, and exceeded the reference range of SOD activity despite advanced age. These results suggested that routine exposure of the residents in the Misasa hot spring district to radon at a concentration about 3 times higher than the national mean induces trace active oxygen in vivo, potentiating products of cancer- suppressive gene and antioxidant function. As the p53 protein level was high in the residents in the Misasa hot spring district, apoptosis of cancer cells may readily occur.

    DOI: 10.1269/jrr.46.21

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  • A comparative study on radioactive characteristics of the minerals for radon therapy

    K Hanamoto, K Yamaoka

    RADIATION MEASUREMENTS   39 ( 2 )   157 - 160   2005年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    To elucidate the mechanism of the radon therapy, we analyzed the radioactive characteristics of the minerals in the famous regions for the radon therapy. Using a high-purity germanium detector, we measured the sludge at the hot bathroom with a high concentration of radon at Misasa Medical Center of Okayama University Medical School, the hokutolite, which was the same kind of mineral at Tamagawa Hot Spring in Japan, and the mineral at the gallery of Badgastein in Austria, which are celebrated regions for the radon therapy. As a result, the ratios of the uranium series to the thorium series for the sludge of Misasa, the hokutolite, and the mineral of Badgastein were 22, 50, and 0.94, respectively. The sludge of Misasa and the hokutolite mainly included the radioelements of the uranium series, while the mineral of Badgastein included the radioelements of both series with almost the same ratio. The ratio of the mineral of Badgastein is similar to that of background (1.1). Furthermore, two kinds of minerals, which are commercially available for radon therapy, were measured using the same detector. The ratios for the two minerals were 0.26 and 0.20, namely, the two minerals included larger radioelements of the thorium series than those of the uranium series. (C) 2004 Elsevier Ltd. All rights reserved.

    DOI: 10.1016/j.radmeas.2004.04.008

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  • MRIファントムの開発

    加藤 博和, 花元 克巳, 川崎 祥二, 澁谷 光一, 黒田 昌宏, 吉村 孝一, 吉田 敦史, 津野田 雅敏, 武本 充広, 金澤 右, 平木 祥夫

    日本医学放射線学会雑誌   65 ( 1 )   77 - 78   2005年1月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • 人工トロン温泉由来の放射能と負イオン(マイナスイオン)の諸特性

    迫田晃弘, 片岡隆浩, 花元克巳, 山岡聖典

    Radioisotopes   54 ( 9 )   375 - 383   2005年

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    掲載種別:研究論文(学術雑誌)  

    DOI: 10.3769/radioisotopes.54.375

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  • Simplification of analysis for comparison of radioactive characteristics and its application to some minerals for radon therapy 査読

    K Hanamoto, K Yamaoka

    HIGH LEVELS OF NATURAL RADIATION AND RADON AREAS: RADIATION DOSE AND HEALTH EFFECTS   1276   253 - 255   2005年

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    記述言語:英語   掲載種別:研究論文(国際会議プロシーディングス)   出版者・発行元:ELSEVIER SCIENCE BV  

    To simplify the analysis of the radioactive characteristics of the minerals for the radon therapy, we developed a simple method to calculate the ratio of the uranium series to the thorium series (U/Th) without using activity. The ratios calculated by this method agreed well with the ratios calculated using the activity. We applied this method to some minerals for the radon therapy. As a result, the U/Th's for the sludge of Misasa, the hokutolite, the mineral of Badgastein, and the two kinds of commercially available minerals were 22, 50, 0.94, 0.26, and 0.20, respectively. (c) 2004 Elsevier B.V. All rights reserved.

    DOI: 10.1016/j.ics.2004.09.029

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  • Effects of radon and thennal therapy on osteoarthritis 査読

    K Yamaoka, F Mitsunobu, K Hanamoto, T Kataoka, Y Tanizaki

    HIGH LEVELS OF NATURAL RADIATION AND RADON AREAS: RADIATION DOSE AND HEALTH EFFECTS   1276   249 - 250   2005年

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    記述言語:英語   掲載種別:研究論文(国際会議プロシーディングス)   出版者・発行元:ELSEVIER SCIENCE BV  

    We examined the temporal changes in antioxidants, immune-, vasoactive- and pain-associated substances in human blood by therapy to elucidate the mechanism of osteoarthritis in which radon therapy is used as a treatment. Results showed that radon inhalation enhanced the antioxidation and immune function, and that the changes in vasoactive and pain-associated substances indicate increases in tissue perfusion brought about by radon therapy. (c) 2004 Published by Elsevier B.V.

    DOI: 10.1016/j.ics.2004.12.013

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  • Development of a phantom compatible for MRI and hyperthermia using carrageenan gel-relationship between T-1 and T-2 values and NaCl concentration

    A Yoshida, H Kato, M Kuroda, K Hanamoto, K Yoshimura, K Shibuya, S Kawasaki, M Tsunoda, S Kanazawa, Y Hiraki

    INTERNATIONAL JOURNAL OF HYPERTHERMIA   20 ( 8 )   803 - 814   2004年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:TAYLOR & FRANCIS LTD  

    The authors developed a phantom, designated as the CAGN phantom, compatible for MRI and hyperthermia that is useful in the fundamental studies of non-invasive MR thermometry. The ingredients of this phantom are carrageenan, GdCl3 as a T-1 modifier, agarose as a T-2 modifier, NaCl as a conductivity modifier, NaN3 as an antiseptic and distilled water. Another phantom that was developed, the CAG phantom, has relaxation times that are adjustable to those of any human tissue. To use this phantom for electromagnetic heating, NaCl was added to change the conductivity of the phantom and clarified the relationship between the conductivity and NaCl concentration. This study examined the relationship between relaxation times and NaCl concentration of the CAGN phantom. The results showed that both T-1 and T-2 values were affected by NaCl and the experimental results led to the empirical formulae expressing the relationship between the relaxation rates (1/T-1, 1/T-2) and the concentrations of GdCl3, agarose and NaCl. The appropriate concentrations of T-1 and T-2 modifiers were calculated from these empirical formulae when making a specified phantom that has the required relaxation times and NaCl concentration.

    DOI: 10.1080/0265673042000199268

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  • MRIにおいて位相方向に出現するアーチファクト

    大野 誠一郎, 小水 満, 花元 克巳, 加藤 博和, 黒田 昌宏, 金澤 右

    日本放射線技術学会雑誌   60 ( 9 )   1261 - 1261   2004年9月

  • 磁化を指標にしたMRIによる温度測定

    花元 克巳, 加藤 博和, 黒田 昌宏, 澁谷 光一, 川崎 祥二, 金澤 右

    日本ハイパーサーミア学会誌   21 ( Suppl. )   60 - 60   2004年9月

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    記述言語:日本語   出版者・発行元:(一社)日本ハイパーサーミア学会  

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  • MRIエコー信号のサンプリング時間測定と画像再構成

    加藤 博和, 花元 克巳, 澁谷 光一, 川崎 祥二, 黒田 昌宏, 吉村 孝一, 吉田 敦史, 津野田 雅敏, 平木 祥夫, 小山 矩

    日本医学放射線学会雑誌   64 ( 5 )   339 - 339   2004年7月

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    記述言語:日本語   出版者・発行元:(公社)日本医学放射線学会  

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  • Biochemical comparison between radon effects and thermal effects on humans in radon hot spring therapy

    K Yamaoka, F Mitsunobu, K Hanamoto, K Shibuya, S Mori, Y Tanizaki, K Sugita

    JOURNAL OF RADIATION RESEARCH   45 ( 1 )   83 - 88   2004年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JAPAN RADIATION RESEARCH SOC  

    The radioactive and thermal effects of radon hot spring were biochemically compared under a sauna room or hot spring conditions with a similar chemical component, using the parameters that are closely involved in the clinic for radon therapy. The results showed that the radon and thermal therapy enhanced the antioxidation functions, such as the activities of superoxide dismutase (SOD) and catalase, which inhibit lipid peroxidation and total cholesterol produced in the body. Moreover the therapy enhanced concanavalin A (ConA)-induced mitogen response and increased the percentage of CD4 positive cells, which is the marker of helper T cells, and decreased the percentage of CD8 positive cells, which is the common marker of killer T cells and suppressor T cells, in the white blood cell differentiation antigen (CD8/CD4) assay. Furthermore, the therapy increased the levels of a atrial natriuretic polypeptide (alphaANP), beta endorphin, adrenocorticotropic hormone (ACTH), insulin and glucose-6-phosphate dehydrogenase (G-6-PDH), and it decreased the vasopression level. The results were on the whole larger in the radon group than in the thermal group. The findings suggest that radon therapy contributes more to the prevention of life-style-related diseases related to peroxidation reactions and immune suppression than to thermal therapy. Moreover, these indicate what may be a part of the mechanism for the alleviation of hypertension, osteoarthritis (pain), and diabetes mellitus brought about more by radon therapy than by thermal therapy.

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  • Inhibitory effects of prior low-dose X-ray irradiation on carbon tetrachloride-induced hepatopathy in acatalasemic mice

    K Yamaoka, T Kataoka, T Nomura, T Taguchi, DH Wang, S Mori, K Hanamoto, S Kira

    JOURNAL OF RADIATION RESEARCH   45 ( 1 )   89 - 95   2004年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JAPAN RADIATION RESEARCH SOC  

    The catalase activities in blood and organs of the acatalasemic (C3H/AnLCs(b)Cs(b)) mouse of C3H strain are lower than those of the normal (C3H/AnLCs(a)Cs(a)) mouse. We examined the effects of prior low-dose (0.5 Gy) X-ray irradiation, which reduced the oxidative damage under carbon tetrachloride-induced hepatopathy in the acatalasemic or normal mice. The acatalasemic mice showed a significantly lower catalase activity and a significantly higher glutathione peroxidase activity compared with those in the normal mice. Moreover, low-dose irradiation increased the catalase activity in the acatalasemic mouse liver to a level similar to that of the normal mouse liver. Pathological examinations and analyses of blood glutamic oxaloacetic and glutamic pyruvic transaminase activity and lipid peroxide levels showed that carbon tetrachloride induced hepatopathy was inhibited by low-dose irradiation. These findings may indicate that the free radical reaction induced by the lack of catalase and the administration of carbon tetrachloride is more properly neutralized by high glutathione peroxidase activity and low-dose irradiation in the acatalasemic mouse liver.

    DOI: 10.1269/jrr.45.89

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  • MRIにおけるサンプリング時間の測定と画像の再構成

    加藤 博和, 花元 克巳, 川崎 祥二, 澁谷 光一, 黒田 昌宏, 小山 矩

    岡山大学医学部保健学科紀要   14 ( 2 )   121 - 128   2004年3月

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    記述言語:日本語   出版者・発行元:岡山大学医学部保健学科  

    MRはX線のように形態画像を表示できる以外に,機能画像,代謝画像,術中画像を表示できることから,重要な撮像モダリティーであるが,成書にはその画像再構成法の具体的な記述はなされていない.そこで,ファントムを用いて具体的に画像を再構成することを試みた.まず矩形ファントムを用いてサンプリング時間の測定を行った.次にMRI MULTI-TEST PHANTOMをスキャンすることによりファントムのエコー信号を採取した.このエコー信号を矩形ファントムで求めたサンプリング時間ごとにサンプリングすることによりk-spaceを得た.このk-spaceから逆フーリエ変換を行うことにより画像の再構成を行った.得られた画像とMRI装置に表示された画像の比較を行い,画像が再現されていることを確認した

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    その他リンク: https://search.jamas.or.jp/index.php?module=Default&action=Link&pub_year=2004&ichushi_jid=J03360&link_issn=&doc_id=20040610190002&doc_link_id=http%3A%2F%2Fousar.lib.okayama-u.ac.jp%2F15198&url=http%3A%2F%2Fousar.lib.okayama-u.ac.jp%2F15198&type=%89%AA%8ER%91%E5%8Aw%81F%89%AA%8ER%91%E5%8Aw%8Aw%8Fp%90%AC%89%CA%83%8A%83%7C%83W%83g%83%8A&icon=https%3A%2F%2Fjk04.jamas.or.jp%2Ficon%2F80034_3.gif

  • Study on biologic effects of radon and thermal therapy on osteoarthritis

    K Yamaoka, F Mitsunobu, K Hanamoto, S Mori, Y Tanizaki, K Sugita

    JOURNAL OF PAIN   5 ( 1 )   20 - 25   2004年2月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:CHURCHILL LIVINGSTONE  

    Radon therapy uses radon (Rn-222) gas, which mainly emits alpha-rays and induces a small amount of active oxygen in the body. We first examined the temporal changes in antioxidants, immune, vasoactive, and pain-associated substances in human blood by therapy to elucidate the mechanism of osteoarthritis in which radon therapy is used as a treatment. Results showed that radon inhalation enhanced the antioxidation and immune function, and the findings suggest that radon therapy contributes to the prevention of osteoarthritis related to peroxidation reactions and immune depression. Moreover, the changes in vasoactive and pain-associated substances indicated increases in tissue perfusion brought about by radon therapy, suggesting that radon inhalation plays a role in alleviating pain.
    Perspective: The findings suggest that an appropriate amount of active oxygen is produced in the body after radon inhalation, and this contributes to the alleviation of the symptoms of active oxygen diseases such as osteoarthritis. (C) 2004 by the American Pain Society.

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  • Using Physiological Indices to Consider the Effects of Negative Air Ions on the Human Body

    Kiyoko Shirai, Kiyonori Yamaoka, Katsumi Hanamoto, Yoshitake Yamamoto

    J. Intl. Soc. Life Info. Sci.   2004年

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  • SAR simulation of interstitial or intracavitary hyperthermia with one or two external flat electrodes for current field heating

    Katsumi Hanamoto, Hirokazu Kato, Masahiro Kuroda, Koichi Shibuya, Shoji Kawasaki, Hiroko Ikeda, Susumu Kanazawa

    Jpn. J. Hyperthermic Oncol.   2004年

  • Development of a tissue-equivalent MRI phantom using carrageenan gel

    K Yoshimura, H Kato, M Kuroda, A Yoshida, K Hanamoto, A Tanaka, M Tsunoda, S Kanazawa, K Shibuya, S Kawasaki, Y Hiraki

    MAGNETIC RESONANCE IN MEDICINE   50 ( 5 )   1011 - 1017   2003年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JOHN WILEY & SONS INC  

    A new tissue-equivalent MRI phantom based on carrageenan gel was developed. Carrageenan gel is an ideal solidifying agent for making large, strong phantoms in a wide variety of shapes. GdCl3 was added as a T-1 modifier and agarose as a T-2 modifier. The relaxation times of a very large number of samples were estimated using 1.5-T clinical MRI equipment. The developed phantom was found to have a T-1 value of 202-1904 ms and a T-2 value of 38-423 ms when the GdCl3 concentration was varied from 0-140 mumol/kg and the agarose concentration was varied from 0-1.6% in a carrageenan concentration that was fixed at 3%. The range of measured relaxation times covered those of all types of human tissue. Empirical formulas linking the relaxation time with the concentration of the modifier were established to enable the accurate and easy calculation of the modifier concentration needed to achieve the required relaxation times. This enables the creation of a phantom having an arbitrary combination of T-1 and T-2 values and which is capable of retaining its shape. Magn Reson Med 50:1011-1017, 2003. (C) 2003 Wiley-Liss, Inc.

    DOI: 10.1002/mrm.10619

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  • 誘電型加温電極を組み合わせた組織内加温のSAR分布シミュレーション

    花元 克巳, 加藤 博和, 澁谷 光一, 川崎 祥二, 黒田 昌宏, 平木 祥夫

    日本ハイパーサーミア学会誌   19 ( Suppl. )   109 - 109   2003年9月

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    記述言語:日本語   出版者・発行元:(一社)日本ハイパーサーミア学会  

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  • MRI特性および電気的特性が人体と等価なファントムの開発 成分濃度とMRIおよび電気的特性の関係

    加藤 博和, 黒田 昌宏, 吉村 孝一, 吉田 敦史, 花元 克巳, 川崎 祥二, 澁谷 光一, 津野田 雅敏, 武本 充広, 平木 祥夫

    日本ハイパーサーミア学会誌   19 ( Suppl. )   149 - 149   2003年9月

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    記述言語:日本語   出版者・発行元:(一社)日本ハイパーサーミア学会  

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  • プロテインキナーゼ阻害剤,H89は温熱耐性発現を促進する

    澁谷 光一, 川崎 祥二, 加藤 博和, 花元 克巳, 黒田 昌宏, 浅海 淳一, 平木 祥夫

    日本ハイパーサーミア学会誌   19 ( Suppl. )   135 - 135   2003年9月

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    記述言語:日本語   出版者・発行元:(一社)日本ハイパーサーミア学会  

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  • カラギーナンゲルを用いた人体組織等価MRIファントムの開発 NaClの緩和時間に及ぼす効果の検討

    吉田 敦史, 加藤 博和, 花元 克巳, 黒田 昌宏, 吉村 孝一, 平木 祥夫

    日本ハイパーサーミア学会誌   19 ( Suppl. )   148 - 148   2003年9月

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    記述言語:日本語   出版者・発行元:(一社)日本ハイパーサーミア学会  

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  • Elevation of antioxidant enzymes in the clinical effects of radon and thermal therapy for bronchial asthma

    F Mitsunobu, K Yamaoka, K Hanamoto, S Kojima, Y Hosaki, K Ashida, K Sugita, Y Tanizaki

    JOURNAL OF RADIATION RESEARCH   44 ( 2 )   95 - 99   2003年6月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JAPAN RADIATION RESEARCH SOC  

    An increased systemic production of oxygen-free radicals by activated inflammatory cells is thought to be involved in the pathophysiology of asthma. The aim of this study is to evaluate the clinical effects of radon and thermal therapy on asthma in relation to antioxidant enzymes and lipid peroxide. Radon and thermal therapy were performed once a week. All subjects went to a hot bathroom with a high concentration of radon, and nasal inhalation of vapor from a hot spring was performed for 40 min once a day under conditions of high humidity. The room temperature was 48degreesC; the room radon concentration was 2,080 Bq/m(3). Blood samples were collected at 2 h, 14, and 28 days after the first therapy. A blood sample also was collected before the first therapy (at body temperature and background radon level) to be used as the control. The forced expiratory volume in one second (%FEV1) was significantly increased 28 days after the first therapy. Oil day 28, the catalase (CAT) activity was significantly increased in comparison with the control. The superoxide dismutase (SOD) activity was significantly increased compared to the control after first inhalation. On days 14 and 28, the lipid peroxide level was significantly decreased in comparison with the control. In conclusion, the present pilot study has shown that radon and thermal therapy improved the pulmonary function of asthmatics by increasing the reduced activities of antioxidant enzymes.

    DOI: 10.1269/jrr.44.95

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  • MRIにおける画像の再構成

    加藤 博和, 花元 克巳, 黒田 昌宏, 澁谷 光一, 川崎 祥二

    岡山大学医学部保健学科紀要   13 ( 2 )   77 - 82   2003年3月

  • H89, a Protein Kinase Inhibitor, Promotes the Development of Thermotolerance in BHK21 and tsAF8 Cells

    Koichi Shibuya, Ayaka, Kobatake, Mio Uezu, Takako Kobayashi, Toshi Matsushita, Shoji Kawasaki, Katsumi Hanamoto, Hirokazu Kato, Masahiro Kuroda, Jun-ichi Asaumi, Yoshio Hiraki

    Jpn. J. Hyperthermic Oncol.   2003年

  • Irradiation effect of synchrotron radiation on crystallization of thin amorphous WO3 film

    Y Kimura, K Hanamoto, Y Nakayama, C Kaito

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   194 ( 2 )   187 - 192   2002年8月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    In order to elucidate the effect of synchrotron radiation (SR) irradiation on crystal growth, crystallization of WO3 films has been performed in vacuum under SR irradiation. The main results were compared with the results of heat treatment of the same film. Upon SR irradiation for 80 s using a toroidal mirror, a catastrophic change occurred, i.e. W3O crystals (A-15 type) with a size of less than 30 nm appeared. Decomposition of the WO3 film started at above 750 degreesC during vacuum heating. W, WO2 and incommensurate WO3 crystals appeared. W3O crystal produced neither intense electron beam irradiation nor vacuum heating. These results will be discussed in terms of the differences caused by excitation with a SR beam, i.e. strong inner shell excitation and ionization of W and O may have taken place.
    (C) 2002 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-583X(02)00685-7

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  • Effects of SR irradiation on tin-doped indium oxide thin film prepared by rf magnetron sputtering

    M Sasaki, K Hanamoto, Y Kimura, C Kaito, H Miki, Y Nakayama

    REVIEW OF SCIENTIFIC INSTRUMENTS   73 ( 3 )   1384 - 1386   2002年3月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:AMER INST PHYSICS  

    The effects of synchrotron radiation (SR) irradiation on the electrical properties of tin-doped In2O3 (ITO) thin films prepared by rf magnetron sputtering have been studied. A white SR beam focused by a cylindrical mirror was used to irradiate ITO thin films at doses of 0.35, 1.98, 3.50, and 6.64 mA h. We have achieved resistivity of 2x10(-4) Omega cm on ITO thin film at an irradiation dose of 3.5 mA h without extra heating. The mobility of the ITO films did not decrease after SR irradiation. The electrical properties in connection with the structural change due to SR are discussed. (C) 2002 American Institute of Physics.

    DOI: 10.1063/1.1423624

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  • Elevation of antioxidant potency in mice brain by low-dose X-ray irradiation and its effect on Fe-NTA-induced brain damage

    Kiyonori Yamaoka, Shuji Mori, Takaharu Nomura, Takehito Taguchi, Takehiko Ito, Katsumi Hanamoto, Shuji Kojima

    Physiological Chemistry and Physics and Medical NMR   34 ( 2 )   119 - 132   2002年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    The increase in lipid peroxide levels in mice brain following Fe 3+ administration was about 50% of that when 1-methyl-4-phenyl 1,2,3,6-tetrahydropyridine (MPTP) was administered. This may be due to excessive oxidation by Fe3+, and was supported by the decrease in activities of antioxidant enzymes, such as superoxide dismutase (SOD), catalase and glutathione peroxidase (GPX), Na+,K+-ATPase activity and membrane fluidity after Fe3+ administration. Relatively low-dose X-ray irradiation (0.5 Gy) inhibited lipid peroxidation associated with Fe 3+ administration and restored the decreased activities of the above antioxidant enzymes and Na+K+-ATPase, and membrane fluidity to the levels in the non-Fe3+-administered group. In the purine metabolism system, uric acid decreased after Fe3+ administration, which may be due to transient impairment of the system for production of uric acid from xanthine by excessive oxidation by Fe3+. However, 0.5 Gy irradiation inhibited this decrease in uric acid, increasing its level to that in the non Fe3+-administrated group. This may be due to factors such as rapid recovery of the activities of the above antioxidant enzymes and Na+,K+-ATPase, and membrane fluidity after 0.5 Gy irradiation. In addition, since no changes were observed in xanthine and uric acid, increased inosine and hypoxanthine may have advanced to a salvage pathway leading to not xanthine but inosine 5′-monophosphate (IMP).

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  • Growth process of carbyne crystals by synchrotron irradiation

    Y Kimura, C Kaito, K Hanamoto, M Sasaki, S Kimura, T Nakada, Y Saito, Y Nakayama

    CARBON   40 ( 7 )   1043 - 1050   2002年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:PERGAMON-ELSEVIER SCIENCE LTD  

    Growth of small carbyne crystals in a thin amorphous carbon film has been observed by high-resolution transmission electron microscopy (HRTEM). The as-deposited film was composed of diamond and graphite crystallites of size 1 nm. Circular alpha-phase carbyne crystals predominantly grew to 20 nm in size and transformed into (alpha+beta)-phase crystals with an elongated shape of 100 nm in length. The typical correlation during the transformation is (220)(alpha)//(301)((alpha+beta)) The c-axes of both grown crystals were oblique to the direction of the electron beam. The growth process of carbyne crystals will be discussed in terms of selective excitation of graphite crystallites by an SR beam. (C) 2002 Elsevier Science Ltd. All rights reserved.

    DOI: 10.1016/S0008-6223(01)00242-1

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  • 気体状放射性ヨウ素(I-125)濃度の簡易測定法

    澁谷光一, 山岡聖典, 永松知洋, 花元克巳, 川崎祥二, 平木祥夫

    Radioisotopes   2002年

  • Adjustment function among antioxidant substances in acatalasemic mouse brain and its enhancement by low-dose x-ray irradiation

    Kiyonori Yamaoka, Takaharu Nomura, Da-Hong Wang, Shuji Mori, Takehito Taguchi, Tetsuya Ishikawa, Katsumi Hanamoto, Shohei Kira

    Physiological Chemistry and Physics and Medical NMR   34 ( 2 )   133 - 144   2002年

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    記述言語:英語   掲載種別:研究論文(学術雑誌)  

    The catalase activities in blood and organs of the acatalasemic (C3H/AnLCsbCsb) mouse of the C3H strain are lower than those of the normal (C3H/AnLCsaCsa) mouse. We conducted a study to examine changes in the activities of antioxidant enzymes, such as catalase, superoxide dismutase (SOD) and glutathione peroxidase (GPX), the total glutathione content, and the lipid peroxide level in the brain, which is more sensitive to oxidative stress than other organs, at 3, 6, or 24 hr following X-ray irradiation at doses of 0.25, 0.5, or 5.0 Gy to the acatalasemic and the normal mice. No significant change in the lipid peroxide level in the acatalasemic mouse brain was seen under non-irradiation conditions. However, the acatalasemic mouse brain was more damaged than the normal mouse brain by excessive oxygen stress, such as a high-dose (5.0 Gy) X-ray. On the other hand, we found that, unlike 5.0 Gy X-ray, a relatively low-dose (0.5 Gy) irradiation specifically increased the activities of both catalase and GPX in the acatalasemic mouse brain making the activities closer to those in the normal mouse brain. These findings may indicate that the free radical reaction induced by the lack of catalase is more properly neutralized by low dose irradiation.

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  • Effects of carbon implantation on the electrical properties of amorphous In2O3 thin film

    K Hanamoto, M Sasaki, H Miki, Y Nakayama

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   184 ( 3 )   371 - 377   2001年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    Carbon ions with an energy of 30 keV have been implanted into amorphous In2O3 thin films at doses of 1 x 10(15) -2 x 10(16) cm(-2). After implantation the films were annealed in air and subsequently in a vacuum at 350 degreesC for 1 h. The electrical resistivities of carbon-implanted films decreased due to the increase in the carrier concentration. However, the whole properties were not much improved compared to a previous experiment by the use of crystalline In2O3 film as a starting material. The relation between the crystal structure and the electrical property will be discussed. (C) 2001 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-583X(01)00788-1

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  • Effect of SR irradiation on In2O3 film

    K Hanamoto, A Hirai, M Sasaki, Y Kimura, K Miyatani, C Kaito, Y Nakayama

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT   467   1213 - 1216   2001年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    The effect of SR irradiation on the crystal growth of indium oxide films prepared by electron-beam evaporation have been studied by X-ray diffraction and high-resolution electron microscopy. An as-deposited film showed In2O3 crystallites with a size of 2-10 nm. The crystallites were destroyed by SR irradiation under oxygen flow, SR irradiation without oxygen flow showed the growth of In2O3 crystallites up to 20 nm in size with accompanying deoxidation and indium-particle growth. The as-deposited film was composed of variously oriented particles. Periodic oxygen decomposition of the film preferentially took place on the (0 0 1)-oriented particle. (C) 2001 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-9002(01)00618-0

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  • Effect of SR irradiation on crystallization of amorphous tin oxide film

    Y Kimura, T Kobayashi, K Hanamoto, M Sasaki, S Kimura, T Nakada, Y Nakayama, C Kaito

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT   467   1221 - 1224   2001年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    In order to see the effect of SR irradiation on crystal growth., crystallization of tin oxide films has been performed in vacuum under SR irradiation, A thin amorphous tin oxide film 50 nm thick was prepared on the carbon substrate by vacuum evaporation of SnO2 power, A SnO crystal appeared between 450-500 degreesC upon vacuum heating, with a preferred orientation of (0 0 1). By SR irradiation using a cylindrical mirror for 20 s, the SnO crystal appeared with the preferred orientation of (1 1 1). The crystal with the crystallographic shear structure was grown by SR irradiation. This growth under a SR beam is discussed in terms of SR beam excitation of lone-pair electrons seen in the SnO crystal structure. (C). 2001 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-9002(01)00624-6

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  • Carbyne formation by synchrotron radiation

    C Kaito, Y Kimura, K Hanamoto, M Sasaki, S Kimura, T Nakada, Y Saito, C Koike, Y Nakayama

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT   467   1217 - 1220   2001年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    Thin carbon films prepared by vacuum evaporation using the arc method were mounted on a standard electron microscope copper grid. They were irradiated by white synchrotron radiation (SR) beam by the use of cylindrical and toroidal mirrors. The irradiated film was examined using a high-resolution electron microscope alpha and alpha + beta mixture carbyne crystals were grown in round and the elongated shapes. The round crystals were composed of 5-10 nm crystallites of a carbyne form. The elongated crystal grew into a single crystal 100 nm in size. The c-axes of both grown crystals were oblique to the film. The growth of the carbynes was discussed as being the result of nucleation due to graphite microcrystallites formed by SR beam irradiation. (C) 2001 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-9002(01)00575-7

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  • Electrical and optical properties of boron and nitrogen implanted In2O3 thin films

    K Hanamoto, M Sasaki, K Miyatani, C Kaito, H Miki, Y Nakayama

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   173 ( 3 )   287 - 291   2001年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    Electrical and optical properties of In2O3 thin films doped with boron and nitrogen have been studied. Boron and nitrogen ions were implanted into In2O3 thin films with an energy of 25 and 35 keV, respectively, at doses of 1 x 10(15)-1.6 x 10(16) cm(-2). After implantation the films were annealed for 1 h in air and subsequently for 1 h in a vacuum. After the two-step annealing at 350 degreesC, the electrical resistivity of the boron implanted sample with a dose of 4 x 10(15) cm(-2) achieved 4.4 x 10(-4) Omega cm with an averaged optical transmittance of 84% at a wavelength between 380 and 780 nm. On the other hand, for nitrogen implanted samples, the resistivity did not improve by ion implantation but the optical transmittance was unchanged. (C) 2001 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-583X(00)00334-7

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  • Electrical and optical properties of carbon implanted In2O3 thin film

    K Hanamoto, M Sasaki, T Yoneda, K Miyatani, H Miki, C Kaito, Y Nakayama

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   168 ( 3 )   389 - 394   2000年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    Electrical and optical properties of In2O3 thin film with carbon ion implantation have been studied. The location of the implanted carbon in the film was also investigated by means of a high-resolution electron microscope. Carbon ions were implanted into In2O3 thin films with an energy of 30 keV at doses of 1 x 10(15) to 2 x 10(16) cm(-2). After implantation the films were annealed for 1 h in air and subsequently for 1 h in a vacuum. After the two step annealing at 350 degrees C, the electrical resistivity achieved for a sample with an ion dose of 5 x 10(15) cm(-2) was 5.4 x 10(-4) Ohm cm with an optical transmittance of 82% at a wavelength of 550 nm. (C) 2000 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-583X(99)01201-X

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  • Low-resistivity highly transparent indium-tin-oxide thin films prepared at room temperature by synchrotron radiation ablation

    Y Akagi, K Hanamoto, H Suzuki, T Katoh, M Sasaki, S Imai, M Tsudagawa, Y Nakayama, H Miki

    JAPANESE JOURNAL OF APPLIED PHYSICS PART 1-REGULAR PAPERS SHORT NOTES & REVIEW PAPERS   38 ( 12A )   6846 - 6850   1999年12月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:JAPAN J APPLIED PHYSICS  

    High-transparency, low-electrical-resistivity indium-tin-oxide (ITO) thin films were prepared on quartz substrates using synchrotron radiation ablation at room temperature. The films had a low resistivity (rho = 1.3 x 10(-4) Omega-cm) and high-transparency properties in the visible region (T = 83% at 550nm). X-ray diffraction patterns indicate that the crystalline ITO film was obtained by room-temperature deposition.

    DOI: 10.1143/JJAP.38.6846

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  • The combined application of PIXE analysis and thermoluminescence (TL) dating for elucidating the origin of iron manufacturing in Japan

    N Hagihara, S Miono, Z Chengzhi, Y Nakayama, K Hanamoto, S Manabe

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   150 ( 1-4 )   635 - 639   1999年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    For elucidating the origin of iron manufacturing in Japan, the usefulness of PIXE analysis was reconfirmed and a new technique of thermoluminescence (TL) dating was applied. Through reproducing experiments of iron manufacturing and forging, PIXE analysis was tested for classifying the iron slag produced from these two different process. The TL dating method was improved for experiments with the iron manufacturing furnace, burnt at high temperature (about 1300 K) and irradiated with relatively low dose. Utilizing PIXE analysis, the iron manufacturing furnace can be distinguished from the older forging furnace used for the imported iron plate. Adopting TL dating, the oldest iron manufacturing furnace can be found out. Some ancient samples in Japan were used as a test of this combined application, and the results were positive, thus proving the suitability of the method. (C) 1999 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-583X(98)01077-5

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  • The discovery of native iron nuggets in the 250 my old bedded chert of Sasayama section, Japan: provenance estimated by PIXE analysis

    S Miono, Y Nakayama, K Hanamoto

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   150 ( 1-4 )   516 - 519   1999年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    A large number of micron sized native iron nuggets (micro iron nugget) occurs in the Triassic-Permian bedded chert. Judging from PIXE analyses and microscopic observations, an interstellar origin is deduced. The occurrence of micro iron nuggets is remarkable and is strongly suggestive of the existence of a neu accretional mechanism in space. (C) 1999 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-583X(98)00917-3

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  • Study on thin SiC layer split by hydrogen implantation in SiC

    T Hosono, K Hanamoto, T Ueno, Kitabatake, I, M Sasaki, Y Nakayama, S Nishino

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   149 ( 1-2 )   67 - 71   1999年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    A thin SiC layer split by H-2 implantation with an energy of 160 keV in SiC wafer has been studied by a new method of optical reflectance interference spectrometry (ORIS). The ORIS spectra revealed that thin SiC layer caused by microsplits is formed over almost whole region of the samples and the thickness of the thin SiC layer is about 630 nm for this implantation. The thickness split has been discussed in connection with the results of atomic force microscopy (AFM) and Rutherford backscattering spectrometry/channeling (RBS/C) The RBS/C measurements also indicated that the surface lattice defects of SiC due to H-implantation decreased by beat treatments. (C) 1999 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-583X(98)00623-5

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  • Annealing effects on the hardening of electroless plated Ni-P layer by boron implantation

    K Hanamoto, M Sasaki, T Miyashita, Y Kido, Y Nakayama, Y Kawamoto, M Fujiwara, R Kaigawa

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   145 ( 3 )   391 - 394   1998年11月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    Annealing effects of hardening of electroless plated Ni-P layer on an iron based alloy have been studied in connection with 200 keV boron ion implantation at a dose of 1 x 10(17) ions/cm(2). Increases of Vickers hardness in the near-urface region were observed to an extent of 17% for the pre-annealed specimens compared to unimplanted ones. Post-nnealed specimens did not show effective hardening by the implantation treatment. The chemical states of implanted ions were studied by X-ray photoelectron spectroscopy (XPS) and the results may suggest that the increase of hardness is not due to the precipitation of nickel borides, but rather due to amorphization of Ni and Ni3P. (C) 1998 Elsevier Science B.V. All rights reserved.

    DOI: 10.1016/S0168-583X(98)00419-4

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  • Anomalous depth profile of implanted fluorine ions in SiO2/Si

    K Hanamoto, H Yoshimoto, T Hosono, A Hirai, Y Kido, Y Nakayama, R Kaigawa

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   140 ( 1-2 )   124 - 128   1998年4月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    Fluorine ions have been implanted into SiO2/Si with an energy of 30 keV at doses of 0.5 and 1 x 10(17) ions/cm(2). Depth profiles of fluorine have been studied by X-ray photoelectron spectroscopy (XPS) for both as-implanted and annealed samples. It was found that depth profiles of fluorine in SiO2/Si did not agree with the predicted Gaussian profiles and showed an enhancement of fluorine concentration in SiO2 region far as-implanted samples. It is thought that anomalous depth profiles may be due to rather high diffusion coefficient in Si than that in SiO2 as a result of fluorine implantation. After annealing at 700 degrees C for 30 min, fluorine concentrations considerably decreased in Si region compared with in SiO2 region. It could be considered that the oxide layers prevent the fluorine diffusion and the fluorine is trapped at around the SiO2/Si interface. (C) 1998 Elsevier Science B.V.

    DOI: 10.1016/S0168-583X(98)00107-4

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  • Structure and crystallization of Sb-Se films prepared by vacuum evaporation method

    C Kaito, T Fujita, T Kimura, K Hanamoto, N Suzuki, S Kimura, Y Saito

    THIN SOLID FILMS   312 ( 1-2 )   93 - 98   1998年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE SA  

    In order to clarify the cause of crystallization into a spherical crystal of low symmetry from amorphous films, various compounds of the Sb-Se system have been prepared and crystallization due re intense electron beam irradiation has been observed in situ. It was revealed that crystallization of small Sb crystals with (0001) orientation is necessary to form the spherical Sb,Se, crystal. (C) 1998 Elsevier Science S.A.

    DOI: 10.1016/S0040-6090(97)00690-1

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  • Effect of fluorine ion implantation on the microstructure and microhardness of AISI 440C stainless steel

    K Hanamoto, M Sasaki, T Miyashita, Y Kido, Y Nakayama, Y Kawamoto, M Fujiwara, R Kaigawa

    NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION B-BEAM INTERACTIONS WITH MATERIALS AND ATOMS   129 ( 2 )   228 - 232   1997年7月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:ELSEVIER SCIENCE BV  

    AISI 440C stainless steel along with pure iron and chromium have been implanted with 30 keV fluorine ions at doses from 5 x 10(16) to 6 x 10(17) ions/cm(2) and surface hardnesses of the 440C steel have been examined. Implanted regions inside the specimens were studied by X-ray photoelectron spectroscopy (XPS) and X-ray diffraction (XRD). The results of XPS and XRD measurements indicate the formation of FeF2 and suggest small grains of CrF2 and non-stoichiometric chromium fluorides in 440C steel. It may be concluded that an increase of the surface hardness in fluorine implanted 440C steel is related to precipitation of metal fluorides and surface oxidation.

    DOI: 10.1016/S0168-583X(97)00227-9

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  • DISKTRON ACCELERATOR

    M SHOJI, K TAKAHASHI, K HANAMOTO, H TSUJI, M TSUBAKIHARA, T NAKABAYASHI, K TSUCHIDA, N OKADA, H NAKANO, K FURUTA, R ONO, Y NAKAYAMA, Y MIYAKE

    REVIEW OF SCIENTIFIC INSTRUMENTS   64 ( 9 )   2466 - 2474   1993年9月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:AMER INST PHYSICS  

    A new type of low-energy ion accelerator has been developed. It includes an eight-storied Disktron generator, newly developed accelerating tubes which hold up to 4 MV/m, both single and tandem acceleration capability, and a compound negative ion source. The Disktron generates 3.2 MV with a dummy load and 2.2 MV with ion beams, and has a voltage stability better than 10(-3) at around 1 MV with a corona feedback stabilizer or a generating voltmeter feedback stabilizer only. The highly stabilized voltage of the Disktron has particularly been allowed to form an ion microbeam of about 1-mum diameter.

    DOI: 10.1063/1.1143905

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  • THEORETICAL CONSIDERATION OF INTENSITY OF AN X-RAY MICROBEAM FORMED BY A HOLLOW GLASS PIPE

    K FURUTA, Y NAKAYAMA, M SHOJI, R KAIGAWA, K HANAMOTO, H NAKANO, Y HOSOKAWA

    REVIEW OF SCIENTIFIC INSTRUMENTS   64 ( 1 )   135 - 142   1993年1月

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    記述言語:英語   掲載種別:研究論文(学術雑誌)   出版者・発行元:AMER INST PHYSICS  

    Intensities of x-ray microbeams formed by the 250-mm-long hollow glass pipes of inner diameters of 27.4, 23.0, and 18.8 mum have been theoretically investigated, by taking account of the slope distribution of microprojections (surface roughness) on the pipe inner wall, using the Monte Carlo method. The intensities for all the pipes calculated on the supposition that each pipe inner wall is perfect (i.e., zero rms of the slope distribution) have been much greater than the experimental values in the x-ray energy region from 6.93 to 19.6 keV. Assuming the slope rms from 2.5 X 10(-4) rad to 3.3 X 10(-3) rad, the calculated results have agreed with the experimental values. Discussions on the results for all the pipes are given in relation to the x-ray anomalous dispersion, the penetration of x rays, the intensity distribution on the x-ray sources used, undulation of the pipes, and the presence of microdust in the pipes.

    DOI: 10.1063/1.1144427

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書籍等出版物

  • 山岡聖典、花元克巳、川辺睦、片岡隆浩、迫田晃弘

    岡山大学出版会  2010年 

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  • Levels of Natural Radiation and Radon Areas: Radiation Dose and Health Effects

    ELSEVIER  2005年 

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  • High Levels of Natural Radiation and Radon Areas: Radiation Dose and Health Effects

    ELSEVIER  2005年 

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  • 標準MRI 画像・図から学ぶ基礎と臨床応用

    (株)オーム社  2004年 

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MISC

  • 焦電性結晶による発生X線の経時変化

    花元克巳, 片岡隆浩, 山岡聖典

    応用物理学会春季学術講演会講演予稿集(CD-ROM)   2021年3月

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    担当区分:筆頭著者  

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  • LiTaO3単結晶による発生X線の経時変化

    花元克巳, 片岡隆浩, 山岡聖典

    応用物理学会春季学術講演会講演予稿集(CD-ROM)   2020年3月

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    担当区分:筆頭著者  

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  • 低線量X線照射による抗酸化機能の亢進が強制水泳誘導無動時間を抑制する

    首藤妃奈, 片岡隆浩, 矢野準喜, 直江翔太, 石田毅, 中田哲也, 大和恵子, 花元克巳, 野村崇治, 山岡聖典

    日本原子力学会春の年会予稿集(CD-ROM)   2020年

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  • マウス諸臓器における過酸化水素の産生量のラドン吸入時間依存性

    片岡隆浩, 神崎訓枝, 迫田晃弘, 首藤妃奈, 矢野準喜, 石田毅, 田中裕史, 花元克巳, 寺東宏明, 光延文裕, 山岡聖典

    日本原子力学会春の年会予稿集(CD-ROM)   2020年

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  • マウス諸臓器中のレドックス状態の違いはラドン吸入による抗酸化機能の亢進に影響する

    片岡隆浩, 神崎訓枝, 迫田晃弘, 首藤妃奈, 矢野準喜, 直江翔太, 石田毅, 田中裕史, 花元克巳, 寺東宏明, 光延文裕, 山岡聖典

    日本原子力学会秋の大会予稿集(CD-ROM)   2020年

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  • ラドン吸入がマウス脳・肝臓に及ぼす酸化ストレスの変化特性

    片岡隆浩, 神崎訓枝, 迫田晃弘, 首藤妃奈, 矢野準喜, 直江翔太, 石田毅, 田中裕史, 花元克巳, 寺東宏明, 光延文裕, 山岡聖典

    日本酸化ストレス学会学術集会プログラム・抄録集   2020年

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  • LiTaO3単結晶による発生X線の結晶表面-ターゲット間距離依存性 II

    花元克巳, 片岡隆浩, 山岡聖典

    応用物理学会春季学術講演会講演予稿集(CD-ROM)   2019年3月

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    担当区分:筆頭著者  

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  • ラドン吸入による抗酸化機能の亢進がマウス諸臓器中の過酸化水素産生に及ぼす作用

    片岡隆浩, 神崎訓枝, 迫田晃弘, 石田毅, 首藤妃奈, 矢野準喜, 田中裕史, 花元克巳, 寺東宏明, 光延文裕, 山岡聖典

    日本原子力学会中国・四国支部研究発表会要旨集   2019年

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  • 低線量X線によるマウス強制水泳試験の無動時間と脳中の酸化ストレスの抑制効果に関する検討

    首藤妃奈, 片岡隆浩, 矢野準喜, 石田毅, 中田哲也, 大和恵子, 花元克巳, 野村崇治, 山岡聖典

    日本原子力学会中国・四国支部研究発表会要旨集   2019年

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  • 低線量X線照射によるマウスのうつ病症状に及ぼす作用に関する基礎的検討

    片岡隆浩, 石田毅, 柚木勇人, 大和恵子, 花元克巳, 野村崇治, 山岡聖典

    アイソトープ・放射線研究発表会要旨集   2019年

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  • 低線量X線照射がマウスの強制水泳に伴う無動時間に及ぼす影響に関する検討

    片岡隆浩, 石田毅, 柚木勇人, 大和恵子, 花元克巳, 野村崇治, 山岡聖典

    日本酸化ストレス学会学術集会プログラム・抄録集   2019年

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  • ハイパーサーミア装置の操作ガイドⅢ 腔内加温法

    築山巌, 加藤博和, 桜井英幸, 光森通英, 永田憲司, 野本由人, 花元克巳, 稲葉誠

    日本ハイパーサーミア学会誌   2003年

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  • 低線量放射線の適応応答に関する最近の研究動向とその意義

    楠原俊昌, 花元克巳, 山岡聖典

    岡山大学医学部保健学科紀要   2002年

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  • Consideration of Synchrotron Radiation Ablation Mechanism

    H. Miki, Sou Lin, T. Kawai, M. Sasaki, K. Hanamoto, S. Imai, Y. Nakayama

    Memoirs of the SR Center Ritsumeikan University   2001年

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▼全件表示

講演・口頭発表等

  • 焦電性結晶による発生X線の経時変化

    花元克巳, 片岡隆浩, 山岡聖典

    応用物理学会春季学術講演会講演予稿集(CD-ROM)  2021年 

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    開催年月日: 2021年

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  • マウス諸臓器における過酸化水素の産生量のラドン吸入時間依存性

    片岡隆浩, 神崎訓枝, 迫田晃弘, 首藤妃奈, 矢野準喜, 石田毅, 田中裕史, 花元克巳, 寺東宏明, 光延文裕, 山岡聖典

    日本原子力学会春の年会予稿集(CD-ROM)  2020年 

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    開催年月日: 2020年

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  • ラドン吸入がマウス脳・肝臓に及ぼす酸化ストレスの変化特性

    片岡隆浩, 神崎訓枝, 迫田晃弘, 首藤妃奈, 矢野準喜, 直江翔太, 石田毅, 田中裕史, 花元克巳, 寺東宏明, 光延文裕, 山岡聖典

    日本酸化ストレス学会学術集会プログラム・抄録集  2020年 

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    開催年月日: 2020年

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  • マウス諸臓器中のレドックス状態の違いはラドン吸入による抗酸化機能の亢進に影響する

    片岡隆浩, 神崎訓枝, 迫田晃弘, 首藤妃奈, 矢野準喜, 直江翔太, 石田毅, 田中裕史, 花元克巳, 寺東宏明, 光延文裕, 山岡聖典

    日本原子力学会秋の大会予稿集(CD-ROM)  2020年 

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    開催年月日: 2020年

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  • LiTaO3単結晶による発生X線の経時変化

    花元克巳, 片岡隆浩, 山岡聖典

    応用物理学会春季学術講演会講演予稿集(CD-ROM)  2020年 

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    開催年月日: 2020年

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  • 低線量X線照射による抗酸化機能の亢進が強制水泳誘導無動時間を抑制する

    首藤妃奈, 片岡隆浩, 矢野準喜, 直江翔太, 石田毅, 中田哲也, 大和恵子, 花元克巳, 野村崇治, 山岡聖典

    日本原子力学会春の年会予稿集(CD-ROM)  2020年 

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    開催年月日: 2020年

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  • ラドン吸入による抗酸化機能の亢進がマウス諸臓器中の過酸化水素産生に及ぼす作用

    片岡隆浩, 神崎訓枝, 迫田晃弘, 石田毅, 首藤妃奈, 矢野準喜, 田中裕史, 花元克巳, 寺東宏明, 光延文裕, 山岡聖典

    日本原子力学会中国・四国支部研究発表会要旨集  2019年 

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    開催年月日: 2019年

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  • 低線量放射線がマウス脳に及ぼす酸化ストレスの検討

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  • X線照射がマウス脳に及ぼす酸化ストレスの評価

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  • LiTaO3単結晶による発生X線の結晶表面-ターゲット間距離依存性

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  • マウスにおけるラドン子孫核種吸入による肺の線量評価

    日本放射線影響学会第54回大会  2011年 

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  • ヒトと小動物におけるラドン及び子孫核種の吸入による吸収線量

    日本放射線影響学会第54回大会  2011年 

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  • 低気圧下でのLiTaO3単結晶による放出電子と発生X線

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  • 中真空中におけるLiTaO3単結晶の電子・X線放出特性

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    日本放射線影響学会第52回大会  2009年 

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  • 焦電結晶による小型放射線源の開発-温度傾斜率による電流特性の検討-

    日本放射線影響学会第52回大会  2009年 

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    日本放射線安全管理学会第8回学術大会  2009年 

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  • 低真空中におけるLiTaO3単結晶の電子放出特性

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    日本放射線影響学会第50回大会  2007年 

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    日本放射線影響学会第50回大会  2007年 

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    日本放射線影響学会第50回大会  2007年 

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    日本放射線影響学会第49回大会  2006年 

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  • Impression and bibliographical consideration on clinical MR thermometry combined with heating devices: from experience of visit to Germany

    日本ハイパーサーミア学会第23回大会合同大会  2006年 

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    日本放射線影響学会第49回大会  2006年 

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  • 天然放射性鉱石の含有化合物と溶出放射性核種の関係

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    日本放射線影響学会第49回大会  2006年 

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    日本放射線影響学会第48回大会  2005年 

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    日本過酸化脂質・フリーラジカル学会第29回大会  2005年 

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    日本放射線影響学会第48回大会  2005年 

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    日本放射線影響学会第48回大会  2005年 

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    日本放射線技術学会第32回秋季学術大会  2004年 

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    第88回日本医学物理学会学術大会  2004年 

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    日本放射線技術学会第32回秋季学術大会  2004年 

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    日本放射線影響学会第47回大会  2004年 

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    日本放射線技術学会第32回秋季学術大会  2004年 

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    日本放射線技術学会第32回秋季学術大会  2004年 

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    日本ハイパーサーミア学会第21回大会  2004年 

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    日本放射線影響学会第47回大  2004年 

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    日本放射線影響学会第47回大  2004年 

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    日本ハイパーサーミア学会第20回大会  2003年 

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    日本ハイパーサーミア学会第20回大会  2003年 

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    第40回 理工学における同位元素・放射線研究発表会  2003年 

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    日本ハイパーサーミア学会第20回大会  2003年 

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    日本放射線影響学会第46回大会  2003年 

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  • Biochemical Comparison between Radon Effects and the Other Effects on Humans in Radon Hot Spring Therapy

    日本放射線影響学会第46回大会  2003年 

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    日本ハイパーサーミア学会第19回大会  2003年 

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    日本放射線影響学会第46回大会  2003年 

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    日本放射線影響学会第45回大会  2002年 

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    日本放射線影響学会第45回大会  2002年 

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  • カラギーナンとジュランガムを併用した三次元温度分布可視化固形ファントムの作成と特性評価

    日本ハイパーサーミア学会第19回大会  2002年 

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  • 三朝ラドン温泉適応症の機構に関する検討―ラドン高濃度熱気浴反復治療による免疫機能の変化特性―

    第39回理工学における同位元素・放射線研究発表会  2002年 

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  • 皮下脂肪を過熱しない多電極RF加温

    日本ハイパーサーミア学会第19回大会  2002年 

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  • 三朝ラドン温泉適応症の機構に関する検討―ラドン高濃度熱気浴反復治療による抗酸化機能の変化特性―

    第39回理工学における同位元素・放射線研究発表会  2002年 

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  • MRIとハイパーサーミアで使用できるファントムの電気的特性

    日本ハイパーサーミア学会第19回大会  2002年 

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  • 吸入ラドンの体内動態に関する検討―実験方法の確立に向けての試み―

    日本放射線影響学会第45回大会  2002年 

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  • ITO透明導電膜への放射光照射効果

    第48回応用物理学関係連合講演会  2001年 

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  • MRIとの併用を目的としたRF組織内加温における基礎的検討

    マイクロ波効果・応用シンポジウム  2001年 

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  • 放射光照射をした透明導電膜の結晶学的考察

    第14回放射光学会年会・放射光科学合同シンポジウム  2001年 

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  • WO3薄膜の結晶化

    日本物理学会第56回年次大会  2001年 

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  • The effects of SR irradiation on tin-doped indium oxide thin film prepared by RF magnetron sputtering

    12th U.S. National Synch. Radiation Instr. Conf.  2001年 

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  • Y. Kimura, T. Kobayashi, *K. Hanamoto, M. Sasaki, S. Kimura, T. Nakada, Y. Nakayama, C. Kaito

    7th Int. Conf. Synch. Radiation. Instr.  2000年 

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  • SR irradiation effect on In2O3 film

    7th Int. Conf. Synch. Radiation. Instr.  2000年 

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  • Carbynes formation by synchrotron radiation

    7th Int. Conf. Synch. Radiation. Instr.  2000年 

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▼全件表示

 

担当授業科目

  • 医用物理学演習 (2021年度) 後期  - 金2

  • 医用物理学特論 (2021年度) 前期  - 金2

  • 医用物理工学演習 (2021年度) 後期  - 火7

  • 医用物理工学特講 (2021年度) 前期  - 火7

  • 卒業研究 (2021年度) 1~3学期  - その他

  • 情報数理科学I (2021年度) 1・2学期  - 木3~4

  • 情報数理科学I (2021年度) 1・2学期  - 木3~4

  • 情報数理科学II (2021年度) 3・4学期  - [第3学期]水1~2, [第4学期]木3~4

  • 情報数理科学II (2021年度) 3・4学期  - [第3学期]水1~2, [第4学期]木3~4

  • 放射化学実験 (2021年度) 3・4学期  - 木5~7

  • 放射線安全管理学実験 (2021年度) 第2学期  - 月5~7,水5~7

  • 放射線物理学I (2021年度) 第1学期  - 水6~7

  • 放射線物理学II (2021年度) 第3学期  - 水5~6

  • 放射線物理学III (2021年度) 第4学期  - 月2~3

  • 放射線計測学 (2021年度) 第2学期  - 水2~3

  • 放射線計測学実験II (2021年度) 3・4学期  - 月5~7

  • 臨床医学特別実習 (2021年度) 第4学期  - 月4~6,水4~6

  • 放射化学実験 (2020年度) 3・4学期  - 木5,木6,木7

  • 放射線安全利用工学1 (2020年度) 第1学期  - 金5,金6

  • 放射線安全管理学実験 (2020年度) 第2学期  - 月5,月6,月7,水5,水6,水7

  • 放射線計測学 (2020年度) 第2学期  - 水2,水3

  • 放射線計測学実験II (2020年度) 3・4学期  - 月5,月6,月7

  • 臨床医学特別実習 (2020年度) 第4学期  - 月4,月5,月6,水4,水5,水6

▼全件表示

 

メディア報道

  • ワーク・ライフ・バランス スタイルブック

    岡山県  p.23-24  2015年3月

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    執筆者:本人以外 

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  • 男性育休 3年で6倍 新聞・雑誌

    山陽新聞  2013年12月27日

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    執筆者:本人以外 

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