研究者詳細 - 冨田　晃司

論文 - 冨田　晃司

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Magnetic Resonance Imaging Guidance for Percutaneous Needle Intervention

Mayu Uka, Yusuke Matsui, Toshihiro Iguchi, Toshi Matsushita, Koji Tomita, Noriyuki Umakoshi, Takahiro Kawabata, Masanori Yamada, Takao Hiraki

Interventional Radiology 2023年

Correction to: Correlation between renal ablation zone in contrast‑enhanced CT and non‑enhanced MRI during the early period following percutaneous cryoablation.

Noriyuki Umakoshi, Toshihiro Iguchi, Takao Hiraki, Yusuke Matsui, Koji Tomita, Mayu Uka, Soichiro Kajita, Motoo Araki, Toshiharu Mitsuhashi, Hideo Gobara, Susumu Kanazawa

Japanese journal of radiology 40 ( 12 ) 1316 - 1316 2022年12月

Evidence on percutaneous radiofrequency and microwave ablation for liver metastases over the last decade

Koji Tomita, Yusuke Matsui, Mayu Uka, Noriyuki Umakoshi, Takahiro Kawabata, Kazuaki Munetomo, Shoma Nagata, Toshihiro Iguchi, Takao Hiraki

Japanese Journal of Radiology 40 ( 10 ) 1035 - 1045 2022年9月

掲載種別：研究論文（学術雑誌）出版者・発行元：Springer Science and Business Media LLC

Abstract

Purpose

This review aimed to summarize the treatment outcomes of percutaneous radiofrequency ablation (RFA) and microwave ablation (MWA) for metastatic liver tumors based on the findings of published studies over the last decade.

Materials and methods

Literature describing the survival outcomes of ablation therapy for liver metastases was explored using the PubMed database on April 26, 2022, and articles published in 2012 or later were selected. The included studies met the following criteria: (i) English literature, (ii) original clinical studies, and (iii) literature describing overall survival (OS) of thermal ablation for metastatic liver tumors. All case reports and cohort studies with fewer than 20 patients and those that evaluated ablation for palliative purposes were excluded.

Results

RFA was the most commonly used method for ablation, while MWA was used in several recent studies. RFA and MWA for liver metastases from various primary tumors have been reported; however, majority of the studies focused on colorectal cancer. The local control rate by RFA and MWA varied widely among the studies, ranging approximately 50–90%. Five-year survival rates of 20–60% have been reported following ablation for colorectal liver metastases by a number of studies, and several reports of 10-year survival rates were also noted.

Conclusion

Comparative studies of local therapies for colorectal liver metastases demonstrated that RFA provides comparable survival outcomes to surgical metastasectomy and stereotactic body radiation therapy.

DOI： 10.1007/s11604-022-01335-5

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その他リンク： https://link.springer.com/article/10.1007/s11604-022-01335-5/fulltext.html

Percutaneous cryoablation combined with prior transcatheter arterial embolization for renal cell carcinomas of 3 cm or larger: a prospective study

Hideo Gobara, Yusuke Matsui, Mayu Uka, Koji Tomita, Noriyuki Umakoshi, Motoo Araki, Jun Sakurai, Toshihiro Iguchi, Takao Hiraki

International Journal of Clinical Oncology 27 ( 10 ) 1589 - 1595 2022年8月

植込み型除細動器(ICD)リード交換後に生じた内胸動脈-腕頭静脈シャント塞栓術の1例

馬越紀行, 宇賀麻由, 宗友一晃, 小牧稔幸, 冨田晃司, 松井裕輔, 櫻井淳, 生口俊浩, 郷原英夫, 平木隆夫, 金澤右

日本インターベンショナルラジオロジー学会雑誌 36 ( 3 ) 320 - 320 2022年8月

CTガイド下心生検にて診断しえたMALTリンパ腫の1例

西垣貴美子, 宇賀麻由, 宗友一晃, 小牧稔幸, 馬越紀行, 冨田晃司, 松井裕輔, 櫻井淳, 生口俊浩, 平木隆夫, 郷原英夫, 片岡仁美, 金澤右

日本インターベンショナルラジオロジー学会雑誌 36 ( 3 ) 322 - 322 2022年8月

コイル塞栓術を施行した左心房近傍の巨大複雑型肺動静脈奇形の1例

宗友一晃, 松井裕輔, 平木隆夫, 生口俊浩, 冨田晃司, 宇賀麻由, 馬越紀行, 小牧稔幸, 郷原英夫, 金澤右

日本インターベンショナルラジオロジー学会雑誌 36 ( 3 ) 320 - 320 2022年8月

Balloon dissectionを併用し尿管損傷を回避し得た腎凍結療法の1例

河村俊一, 冨田晃司, 小牧稔幸, 馬越紀行, 宇賀麻由, 松井裕輔, 櫻井淳, 生口俊浩, 郷原英夫, 平木隆夫

日本インターベンショナルラジオロジー学会雑誌 36 ( 3 ) 322 - 322 2022年8月

CTガイド下心生検にて診断しえたMALTリンパ腫の1例

西垣貴美子, 宇賀麻由, 宗友一晃, 小牧稔幸, 馬越紀行, 冨田晃司, 松井裕輔, 櫻井淳, 生口俊浩, 平木隆夫, 郷原英夫, 片岡仁美, 金澤右

日本インターベンショナルラジオロジー学会雑誌 36 ( 3 ) 322 - 322 2022年8月

Balloon dissectionを併用し尿管損傷を回避し得た腎凍結療法の1例

河村俊一, 冨田晃司, 小牧稔幸, 馬越紀行, 宇賀麻由, 松井裕輔, 櫻井淳, 生口俊浩, 郷原英夫, 平木隆夫

日本インターベンショナルラジオロジー学会雑誌 36 ( 3 ) 322 - 322 2022年8月

植込み型除細動器(ICD)リード交換後に生じた内胸動脈-腕頭静脈シャント塞栓術の1例

馬越紀行, 宇賀麻由, 宗友一晃, 小牧稔幸, 冨田晃司, 松井裕輔, 櫻井淳, 生口俊浩, 郷原英夫, 平木隆夫, 金澤右

日本インターベンショナルラジオロジー学会雑誌 36 ( 3 ) 320 - 320 2022年8月

コイル塞栓術を施行した左心房近傍の巨大複雑型肺動静脈奇形の1例

宗友一晃, 松井裕輔, 平木隆夫, 生口俊浩, 冨田晃司, 宇賀麻由, 馬越紀行, 小牧稔幸, 郷原英夫, 金澤右

日本インターベンショナルラジオロジー学会雑誌 36 ( 3 ) 320 - 320 2022年8月

Up-to-date evidence on image-guided thermal ablation for metastatic lung tumors: a review

Yusuke Matsui, Koji Tomita, Mayu Uka, Noriyuki Umakoshi, Takahiro Kawabata, Kazuaki Munetomo, Shoma Nagata, Toshihiro Iguchi, Takao Hiraki

Japanese Journal of Radiology 40 ( 10 ) 1024 - 1034 2022年7月

掲載種別：研究論文（学術雑誌）出版者・発行元：Springer Science and Business Media LLC

Abstract

The aim of this review was to summarize the latest evidence on image-guided thermal ablation therapies for lung metastases. PubMed was used to search for relevant articles that reported the oncological outcomes of thermal ablation for metastatic lung tumors, and those published in 2010 or later were selected for review. Ablative therapies were applied for lung metastases from various types of primary tumors, but most commonly colorectal ones. Radiofrequency ablation (RFA) was the most evaluated technique, followed by microwave ablation (MWA). The local control rates of ablative therapies were generally favorable, approximately 80–90% in many studies. Representative studies demonstrated promising overall survival rates of approximately 50% or higher 5 years after ablation for lung metastases from colorectal cancer or mixed types of primary tumors. Nevertheless, the survival outcomes varied depending on the type of primary tumor and background factors of patients such as other metastases and comorbidities. Several studies had aimed to compare the outcomes of various ablative therapies such as RFA, MWA, and cryoablation; however, conclusive data are not yet available to determine the most appropriate ablation modality for lung metastases. Further data accumulation is needed, especially for long-term outcomes and comparisons with other therapies.

DOI： 10.1007/s11604-022-01302-0

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その他リンク： https://link.springer.com/article/10.1007/s11604-022-01302-0/fulltext.html

Percutaneous cryoablation for clinical T3a renal cell carcinoma (< 7 cm) with segmental vein involvement or perinephric fat invasion based on preoperative evaluation of high-resolution multidetector computed tomography scan

Mayu Uka, Toshihiro Iguchi, Nanako Okawa, Yusuke Matsui, Koji Tomita, Noriyuki Umakoshi, Kazuaki Munetomo, Hideo Gobara, Motoo Araki, Takao Hiraki

Japanese Journal of Radiology 40 ( 11 ) 1201 - 1209 2022年6月

掲載種別：研究論文（学術雑誌）出版者・発行元：Springer Science and Business Media LLC

Abstract

Purpose

To retrospectively assess the feasibility, safety, renal function, technique efficacy rate, and survival of patients with clinical T3a renal cell carcinoma (RCC).

Materials and methods

Sixteen cryoablation sessions were performed in 14 patients (10 men; mean age, 69.8 ± 10.5 years; range, 49–90 years) with 14 clear cell T3a RCCs (mean, 3.3 ± 0.9 cm; range, 1.9–5.2 cm). One patient was on dialysis. Transcatheter arterial embolization was performed before cryoablation in 15 sessions. The primary endpoint was the technique efficacy rate. The secondary endpoints included feasibility, safety, renal function, and survival.

Results

Cryoablation was technically successful in all RCC cases. In two RCCs, cryoablation was performed twice because of local tumor progression. No major adverse events were observed. All patients were alive without metastases, with a median follow-up of 45 months (6−93 months). Complete response was achieved by cryoablation in 11 RCCs (78.6%). The primary and secondary technique efficacy rates were 77.1% and 84.4% at 1 year, 57.9% and 73.9% at 3 years, and 57.9% and 73.9% at 5 years, respectively. One patient underwent dialysis given a total contralateral nephrectomy due to another RCC 1 month after initial cryoablation and a total ipsilateral nephrectomy 46 months after initial cryoablation due to local progression. Except for two dialysis patients, of the 12 patients with a median follow-up of 41 months (6–93 months), none were on dialysis.

Conclusion

Cryoablation was safe and effective in T3a RCC, which mainly involved the renal venous branches and may represent an alternative treatment for inoperable patients.

DOI： 10.1007/s11604-022-01297-8

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その他リンク： https://link.springer.com/article/10.1007/s11604-022-01297-8/fulltext.html

Early enlarging cavitation after percutaneous radiofrequency ablation of lung tumors: Incidence, risk factors and outcome. 国際誌

Koji Tomita, Toshihiro Iguchi, Yusuke Matsui, Mayu Uka, Noriyuki Umakoshi, Toshiharu Mitsuhashi, Jun Sakurai, Hideo Gobara, Susumu Kanazawa, Takao Hiraki

Diagnostic and interventional imaging 103 ( 10 ) 464 - 471 2022年5月

記述言語：英語掲載種別：研究論文（学術雑誌）

PURPOSE: The purpose of this study was to retrospectively determine the incidence of early enlarging cavitation after percutaneous radiofrequency ablation (RFA) of lung tumor and identify risk factors associated with their occurrence. PATIENTS AND METHODS: A total of 245 patients (140 men, 105 women; mean age, 62.7 ± 11.8 [SD] years; age range: 31-87 years) with 605 lung tumors who were treated using 401 RFA sessions from April 2010 to March 2020 were included. Of which, 31 patients with 38 early enlarging cavitation and control group (151 patients with 228 tumors) were analyzed. Early enlarging cavitation was defined as cavities with an enlarged size (>3 cm) occurring on ablated lesions within seven days after RFA. Incidence of cavitation, risk and post-procedural factors of occurrence, major adverse events (AEs) that occurred in RFA sessions with cavitation, and course of cavitation were evaluated. AEs were classified using the CIRSE classification system for complications. RESULTS: Thirty-eight cavities (6.3%, 38/605 tumors) in 31 patients occurred in an average of 3.1 ± 1.7 days (range, 1-7 days) after 32 RFA sessions. Distance from pleura ≥ 20 mm, contact with vessel ≥ 3 mm, multitined expandable electrode ≥ 3 cm, and bronchus ≥ 2 mm encompassed in the ablation zone were independent risk factors of occurrence. Fever ≥ 38.5 °C, white blood cell count ≥ 10,000/μl one day after RFA, and steroid therapy were independent post-procedural factors of occurrence. Twenty-four Grade 3 and two Grade 6 AEs occurred. Twenty-nine cavities disappeared within a mean duration of 111.9 ± 64.9 (SD) days (range: 44-274 days) and four remained with a mean follow-up of 279.2 ± 174 (SD) days; five patients were lost to follow-up. CONCLUSIONS: Early enlarging cavitation occurs in 6.3% of lung tumors treated with RFA and are associated with 26 major AEs in 32 sessions. Aforementioned procedural factors and post-procedural inflammation were significant risk factors of occurrence.

DOI： 10.1016/j.diii.2022.05.004

PubMed

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Correlation between renal ablation zone in contrast-enhanced CT and non-enhanced MRI during the early period following percutaneous cryoablation.

Noriyuki Umakoshi, Toshihiro Iguchi, Takao Hiraki, Yusuke Matsui, Koji Tomita, Mayu Uka, Soichiro Kajita, Motoo Araki, Toshiharu Mitsuhashi, Hideo Gobara, Susumu Kanazawa

Japanese journal of radiology 40 ( 10 ) 1087 - 1095 2022年5月

記述言語：英語掲載種別：研究論文（学術雑誌）

PURPOSE: To retrospectively evaluate and correlate the contrast-enhanced computed tomography (CECT) and non-enhanced magnetic resonance imaging (MRI) during the early period following renal cryoablation. MATERIALS AND METHODS: Both dynamic CECT and non-enhanced MRI were performed within 4 days following cryoablation in 34 renal tumors in 33 patients. The renal volumes of the unenhanced regions on dynamic CECT (nephrogenic phase, 4 mm thickness) and the regions with signal intensity changes on non-enhanced MRI (fat-suppressed T2-weighted image, 4 mm thickness) were evaluated. Fusion images of the axial, coronal, and sagittal sections of CECT and MRI images were created from the maximum cross-section of the renal tumor, and the match score of each image was visually evaluated on a 5-point scale. RESULTS: The mean renal volume of the unenhanced regions on CECT and those with signal intensity changes on non-enhanced MRI following cryoablation were 29.5 ± 19.9 cm3 (range, 4.3-97.4 cm3) and 30.7 ± 19.8 cm3 (range, 6.7-94.0 cm3), respectively; the difference between them was -1.17 cm3 (95% confidence interval [CI] -2.74, 0.40, P = 0.139). The Pearson's product-moment correlation coefficient (r = 0.975; 95% CI, 0.951, 0.988; P < 0.0001) showed a strong correlation between the volumes. The average match score between CECT and non-enhanced MRI was as high as 4.5 ± 0.5 points (radiologist 1, 4.3 ± 0.5; radiologist 2, 4.7 ± 0.5). Local tumor control rate was 94.1% (32/34 tumors) and recurrence-free survival rate was 82.0% (95% CI: 64.2%, 91.5%) at 5 years. CONCLUSIONS: The region with signal intensity changes on non-enhanced MRI was strongly correlated with the unenhanced region on CECT during the early period following renal cryoablation.

DOI： 10.1007/s11604-022-01285-y

PubMed

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Kidney cyst infection through a fistula between bladder and retroperitoneal abscess in a polycystic kidney disease patient. 国際誌

Takato Nakadoi, Kenji Tsuji, Takehiro Iwata, Eriko Eto, Hisashi Masuyama, Koji Tomita, Takao Hiraki, Shinji Kitamura, Hitoshi Sugiyama, Jun Wada

Nephrology (Carlton, Vic.) 27 ( 4 ) 383 - 384 2022年4月