Language：English   Publishing type：Research paper (scientific journal)  

BACKGROUND: Although excessive alcohol consumption is a critical factor for non-communicable diseases, its clinical relevance to chronic kidney disease is controversial. METHODS: This retrospective cohort study, including 80,765 men and 88,507 women aged 40-74 years who underwent annual health checkups in Japan between April 2012 and March 2017, assessed a dose-dependent association between alcohol consumption (rare, occasional, and daily drinkers with ≤ 19, 20-39, 40-59, and ≥ 60 g/day) and incidence of ≥ 30% decline in estimated glomerular filtration rate (eGFR), eGFR < 60 ml/min/1.73 m2 and presence of proteinuria (dipstick urinary protein ≥ 1 +), using Cox proportional hazards models adjusted for clinically relevant factors. RESULTS: The incidence of ≥ 30% eGFR decline was observed in 1231 (1.5%) men and 1291 (1.5%) women during the median observation period of 2.8 and 2.9 years, respectively. In men, daily drinkers consuming ≥ 40 g/day of ethanol were at significantly high risk for ≥ 30% eGFR decline (adjusted hazard ratio [95% confidence interval] of rare, occasional, and daily drinkers with ≤ 19, 20-39, 40-59, and ≥ 60 g/day: 1.00 [reference], 1.05 [0.87, 1.27], 0.99 [0.80, 1.21], 1.05 [0.88, 1.26], 1.23 [1.01, 1.51], 1.61 [1.22, 2.11], respectively). Similar dose-dependent associations with incidence of eGFR < 60 ml/min/1.73 m2 and proteinuria were observed in men. Contrary to men, alcohol consumption was not associated with eGFR decline and proteinuria in women. CONCLUSION: Men with alcohol consumption ≥ 40 g/day were at a high risk of eGFR decline and development of proteinuria.

DOI： 10.1007/s40620-025-02339-w

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DOI： 10.1093/gerona/glaf100

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Authorship：Lead author,　Corresponding author  

DOI： 10.2188/jea.JE20240165.

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Authorship：Lead author,　Corresponding author  

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Authorship：Lead author,　Corresponding author  

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DOI： 10.3390/nu16142361.

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DOI： 10.1016/j.jdent.2024.105144

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Authorship：Lead author  

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Publishing type：Research paper (scientific journal)   Publisher：Japan Prosthodontic Society  

DOI： 10.2186/ajps.16.22

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Publishing type：Research paper (scientific journal)   Publisher：SAGE Publications  

Purpose

This study aimed to confirm the clinical impact of living arrangements on incidence of frequent alcohol consumption in university students.

Design

A retrospective cohort study.

Setting

A national university in Japan.

Subjects

17,774 university students.

Measures

The association between living arrangements on admission and the incidence of frequent alcohol consumption (≥4 days/week) was assessed using multivariable-adjusted Cox proportional-hazards models.

Results

Among 5,685, 692, and 5,151 male students living with family, living in the dormitory, and living alone, 5.0%, 6.2%, and 5.8% reported frequent alcohol consumption during the median observational period of 3.0 years, respectively. Living in the dormitory and living alone were identified as significant predictors of frequent alcohol consumption (multivariable-adjusted hazard ratios: 1.00 [reference], 1.39 [1.01-1.92], and 1.21 [1.03-1.42], respectively). On the contrary, living arrangements were not associated with the incidence of frequent alcohol consumption among of 6,091 female students, partly because of low incidence of frequent alcohol consumption (2.3%, 1.4%, and 2.6%, respectively).

Conclusions

Living arrangements predicted frequent alcohol consumption among male university students, whereas not among female university students.

DOI： 10.1177/08901171231224882

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Other Link： http://journals.sagepub.com/doi/full-xml/10.1177/08901171231224882

Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

Previous cohort studies have reported conflicting associations between alcohol consumption and chronic kidney disease, characterized by proteinuria and low glomerular filtration rate (GFR). This systematic review, which included 14,634,940 participants from 11 cohort studies, assessed a dose-dependent association of alcohol consumption and incidence of proteinuria and low estimated GFR (eGFR) of &lt;60 mL/min/1.73 m2. Compared with non-drinkers, the incidence of proteinuria was lower in drinkers with alcohol consumption of ≤12.0 g/day (relative risk 0.87 [95% confidence interval 0.83, 0.92]), but higher in drinkers with alcohol consumption of 36.1–60.0 g/day (1.09 [1.03, 1.15]), suggesting a J-shaped association between alcohol consumption and the incidence of proteinuria. Incidence of low eGFR was lower in drinkers with alcohol consumption of ≤12.0 and 12.1–36.0 than in non-drinkers (≤12.0, 12.1–36.0, and 36.1–60.0 g/day: 0.93 [0.90, 0.95], 0.82 [0.78, 0.86], and 0.89 [0.77, 1.03], respectively), suggesting that drinkers were at lower risk of low eGFR. In conclusion, compared with non-drinkers, mild drinkers were at lower risk of proteinuria and low eGFR, whereas heavy drinkers had a higher risk of proteinuria but a lower risk of low eGFR. The clinical impact of high alcohol consumption should be assessed in well-designed studies.

DOI： 10.3390/nu15071592

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Language：English   Publishing type：Research paper (scientific journal)  

DOI： 10.1016/j.jamda.2023.01.008

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Publishing type：Research paper (scientific journal)   Publisher：MDPI AG  

Frequency of alcohol drinking is a potential predictor of binge drinking of alcohol, a serious social problem for university students. Although previous studies have identified skipping breakfast as a predictor of various health-compromising behaviors and cardiometabolic diseases, few studies have assessed the association between skipping breakfast and the incidence of frequent alcohol drinking. This retrospective cohort study included 17,380 male and 8799 female university students aged 18–22 years admitted to Osaka universities between 2004 and 2015. The association between breakfast frequency (eating every day, skipping occasionally, and skipping often/usually) and the incidence of frequent alcohol drinking, defined as drinking ≥4 days/week, was assessed using multivariable-adjusted Cox proportional hazards models. During the median observational period of 3.0 years, 878 (5.1%) men and 190 (2.2%) women engaged in frequent alcohol drinking. Skipping breakfast was significantly associated with the incidence of frequent alcohol drinking (adjusted hazard ratios [95% confidence interval] of eating every day, skipping occasionally, and skipping often/usually: 1.00 [reference], 1.02 [0.84–1.25], and 1.48 [1.17–1.88] in men; 1.00 [reference], 1.60 [1.03–2.49], and 3.14 [1.88–5.24] in women, respectively). University students who skipped breakfast were at a higher risk of frequent alcohol drinking than those who ate breakfast every day.

DOI： 10.3390/nu14132657

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Authorship：Lead author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Springer Science and Business Media LLC  

PURPOSE: Although home care improves patients' quality of life (QOL), several studies have suggested that home care lowers the QOL of family caregivers and decreases their mortality. To alleviate the deleterious impact of home care on caregivers, the major burdens on caregivers and the clinical characteristics of the caregivers vulnerable to the major burden needs to be clarified. METHOD: A survey questionnaire was distributed to 710 family caregivers of patients with cancer in Japan, and 342 valid responses were obtained (valid response rate: 48.2%). The Burden Index of Caregivers was used to identify the major burden on caregivers. To assess the associations of the patients' care needs level and other clinically relevant factors with the major burden, a multivariable-adjusted logistic regression model was used. RESULTS: The time-dependent burden was identified as a major burden. An adjusted model showed a nonlinear association between the care needs level and the time-dependent burden, in which the caregivers of the patients who required moderate care needs level had the highest time-dependent burden [adjusted odds ratio of none, mild, moderate, and severe care needs levels: 0.50 (95% confidence interval 0.07-2.12), 1.08 (0.43-2.57), 1.87 (1.01-3.52), and 1.00 (reference), respectively]. Additionally, older patients and younger caregivers were significantly associated with a time-dependent burden. CONCLUSION: The time-dependent burden was highest in caregivers at the moderate care needs level and younger caregivers. An imbalance between the demand and supply of care services may be improved by considering the clinical characteristics of both patients and caregivers.

DOI： 10.1007/s00520-021-06579-x

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Other Link： https://link.springer.com/article/10.1007/s00520-021-06579-x/fulltext.html

Authorship：Lead author,　Corresponding author   Publishing type：Research paper (scientific journal)   Publisher：Japan Academy of Nursing Science  

DOI： 10.5630/jans.41.29

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Language：English   Publishing type：Research paper (scientific journal)  

BACKGROUND: Japan has the largest population of older adults in the world; it is only growing as life expectancy increases worldwide. As such, solutions to potential obstacles must be studied to maintain healthy, productive lives for older adults. In 2011, the Japanese government has started a policy to increase "Elderly Housing with Care Services (EHCS)", which is one of a private rental housing, as a place where safe and secure end-of-life care can be provided. The government expect for them to provide end-of-life care by collaborating with the Home-Visit Nursing Agencies (HVNA). The purpose of this study is to clarify the situation of the end-of-life care provision in EHCS in collaboration with HVNA and to examine the factors that associate with the provision of the end-of-life care in EHCS. METHODS: A two-stage nationwide survey (fax and mail surveys) were conducted. Of the 5,172 HVNA of the National Association for Visiting Nurse Services members, members from 359 agencies visited EHCS. Logistic regression analysis was conducted with the provision of end-of-life care to EHCS in 2017 as the dependent variable, and the following as independent variables: characteristics of HVNA and EHCS; characteristics of residents; collaborations between HVNA and EHCS; and the reasons for starting home-visit nursing. RESULTS: Of the 342 HVNA who responded to the collaborations with EHCS, 21.6% provided end-of-life care. The following factors were significantly associated with the provision of end-of-life care to inmates in elderly care facilities: being affiliated with a HVNA, admitting many residents using long-term care insurance, collaborating with each other for more than three years, and started visiting-nurse services after being requested by a resident's physician. CONCLUSIONS: This study clarified the situation of the provision of end-of-life care in EHCS in collaboration with HVNA and the related factors that help in providing end-of-life care in EHCS.

DOI： 10.1186/s12904-021-00847-7

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Authorship：Lead author,　Corresponding author   Language：English   Publishing type：Research paper (scientific journal)   Publisher：Elsevier BV  

PURPOSE: The benefits of respite care in reducing the burden of caregivers of children with disabilities are well known; however, few studies have effectively quantified such benefits. The aim of the present study was to develop and validate a measure for evaluating the benefit of respite care provided to family caregivers of children with disabilities. DESIGN AND METHODS: This was a cross-sectional study. We distributed a survey questionnaire to 465 family caregivers between March and April 2017. Participants were asked to respond to items regarding benefits of respite care for themselves and their children. RESULTS: Data in relation to four domains (Child Development, Sense of Peace and Life Fulfillment among Caregivers, Mental Health Support for the Caregiver, and Expansion of Perspectives and Future Vision) were extracted to assess the benefits of using respite care. The full-scale Cronbach's α coefficient was 0.89 and ranged between 0.73 and 0.88 for each individual domain. CONCLUSIONS: The newly developed measure for assessing the benefits of respite care for family caregivers of children with disabilities was highly reliable and valid. PRACTICE IMPLICATIONS: This objective tool would allow healthcare practitioners to review the quality of respite care they provide and subsequently help them identify ways to improve.

DOI： 10.1016/j.pedn.2020.01.016

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AIM: This pilot study aimed to analyze the cost-effectiveness of visiting nursing care, to establish a new evaluation method considering both the quality and cost of visiting nursing care. METHOD: Participants were 384 caregivers from 10 certified home-visit nursing agencies that support patients in severe conditions in Japan. They completed a survey assessing the number of nursing care visits carried out in November 2016, visiting nursing receipt data for 1 month of study and quality of life (QOL), as measured by the EuroQol-5 Dimension at their last visit, which took place 1 month later. RESULTS: We categorized participants into low-charge and high-charge groups. In the low-charge group, no relationship was found between high QOL and frequency of implementation of each type of care. In the high-charge group, participants with high frequencies of "medicine management and instruction," "description and guidance for diseases and treatment," and "nutrition and diet care" had higher levels of QOL. CONCLUSIONS: This research might contribute to establishing a cost assessment system for home-visit nursing care in Japan, which is expected to be useful in countries where the average age of the population is increasing. Care provided by visiting nurses might be divided into care items that related or did not relate to QOL. Therefore, when evaluating the quality and cost-effectiveness of visiting nursing care, it is necessary to construct an evaluation system that considers these aspects and obtain appropriate data. Geriatr Gerontol Int 2020; 20: 36-41.

DOI： 10.1111/ggi.13816

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Authorship：Lead author   Language：Japanese   Publisher：Japan Academy of Nursing Science  

<p>Aim: This study aimed to study the services offered by function-enhanced home nursing agencies for different patient needs.</p><p>Method: We targeted nationwide function-enhanced home nursing agencies and 515 users. A survey was conducted on care implementation using a data input system developed in advance.</p><p>Results: Most frequently availed home-visit nursing care services are "explanation and guidance on diseases and treatments (odds ratio [OR] = 4.535) towards the final stages of cancer," "assistance and guidance for dressing users with intractable neurological diseases (OR = 2.276)," "mental support (OR = 3.062)," and "decision making support (OR = 3.701) for pediatric users."</p><p>Conclusion: The services frequently availed by users of home nursing care were identified. It is necessary to consider user characteristics to provide the care of home-visit nursing.</p>

DOI： 10.5630/jans.39.183

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Authorship：Lead author,　Corresponding author   Language：Japanese   Publisher：Japan Academy of Nursing Science  

<p>Aim: This study aimed to investigate the status and factors of implementing respite care in a visiting nursing stations and adjoining office for children requiring medical care.</p><p>Method: A survey questionnaire was distributed to 1,154 visiting nursing stations for children between August and September, 2017. Statistical analyses were performed using χ² test and Mann-Whitney U test.</p><p>Results: There were 381 valid responses (response rate: 32.8%). The respite care implementation rate was 57.1% and there was a relationship between the adjoining of After-school day care service including child development support and respite care implementation rate (p = .004). The factors related to the implementation of respite care were the number of nursing staff, needs, standardization of the quality of nursing, recruiting personnel, staff's ability to communicate with children and family caregivers, and staff's ability to build relationships of trust with family caregivers (p = .00–.04).</p><p>Conclusion: As per this study, it was suggested that improvement of respite care implementation was necessary, based on factors such as personnel allocation, unified quality of nursing care, acquisition of basic nursing skills.</p>

DOI： 10.5630/jans.39.100

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Authorship：Lead author,　Corresponding author   Language：Japanese  

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J-GLOBAL

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Language：Japanese   Publisher：日本公衆衛生学会  

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Language：Japanese   Publisher：日本公衆衛生学会  

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Language：Japanese   Publisher：日本公衆衛生学会  

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Language：Japanese   Publisher：日本公衆衛生学会  

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Authorship：Lead author,　Corresponding author  

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Authorship：Lead author   Language：Japanese  

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