1. Two opsin 3-related proteins in the chicken retina and brain: A TMT-type opsin 3 is a blue-light sensor in retinal horizontal cells, hypothalamus, and cerebellum. Kato M et al., PLoS One. 2016 Nov 18;11(11):e0163925. 2. Two UV-sensitive photoreceptor proteins, Opn5m and Opn5m2 in ray-finned fish with distinct molecular properties and broad distribution in the retina and brain. Sato K et al., PLoS One. 2016 May 11;11(5):e0155339. 3. Evolution of mammalian Opn5 as a specialized UV-absorbing pigment by a single amino acid mutation. Yamashita T et al., J Biol Chem, 2014, 289, 3991-4000. 4. A non-mammalian type opsin 5 functions dually in the photoreceptive and non-photoreceptive organs of birds. Ohuchi H et al., PLoS One, 2012, 7, e31534. 5. Opn5 is a UV-sensitive bistable pigment that couples with Gi subtype of G protein. Yamashita T et al., Proc Natl Acad Sci U S A, 2010, 107, 22084-22089. 6. Expression patterns of the opsin 5-related genes in the developing chicken retina. Tomonari S et al., Dev Dyn, 2008, 237, 1910-1922. Studies of novel photopigment-expressing neurons in the vertebrate retina and brain2004.04Expression analysis of Dickkopf-related protein 3 (Dkk3) suggests its pleiotropic roles for a secretory glycoprotein in adult mouse. Inoue J et al., J Mol Histol. 2017 Feb;48(1):29-39.Studies of biological functions for tumor-associated genes 2012.041. Leg regeneration is epigenetically regulated by histone H3K27 methylation in the cricket Gryllus bimaculatus. Hamada Y et al., Development. 2015 Sep 1;142(17):2916-27. 2. Analysis of RNA-Seq data reveals involvement of JAK/STAT signalling during leg regeneration in the cricket Gryllus bimaculatus. Bando T et al., Development. 2013 Mar;140(5):959-64. 3. Wakayama Symposium: Epithelial-mesenchymal interactions in eyelid development. Ohuchi H, Ocul Surf. 2012 Oct;10(4):212-6. Studies of molecular mechanisms for tissue regeneration and organogenesis 1998.031. Relationship between somatic mosaicism of Pax6 mutation and variable developmental eye abnormalities-an analysis of CRISPR genome-edited mouse embryos. Yasuo A et al., Sci Rep. 2017 Dec;7(1):53. 2. Autopsy Case of Bilateral Optic Nerve Aplasia with Microphthalmia: Neural Retina Formation Is Required for the Coordinated Development of Ocular Tissues. Ohuchi H et al., Acta Med Okayama. 2016;70(2):131-7. 3. The expression of LIM-homeobox genes, Lhx1 and Lhx5, in the forebrain is essential for neural retina differentiation. Inoue J et al., Dev Growth Differ. 2013 Sep;55(7):668-75. 4. Molecular aspects of eye evolution and development: from the origin of retinal cells to the future of regenerative medicine. Ohuchi H. Acta Med Okayama. 2013;67(4):203-12. Review. 5. Lhx1 in the proximal region of the optic vesicle permits neural retina development in the chicken. Kawaue T et al., Biology Open. 2012;1:1083-1093. 

Photograph

Name

OHUCHI Hideyo

Affiliation

Graduate School of Medicine, Dentistry and Pharmaceutical Sciences

Title

Professor

Sex

female

Research areas, keyword

Histology, Developmental Biology, Regenerative Medicine and Biology, Molecular Biology

Research Subject 【 display / non-display

  • Subject:Studies of novel photopigment-expressing neurons in the vertebrate retina and brain

    Object:

  • Subject:Studies of biological functions for tumor-associated genes

  • Subject:Studies of molecular mechanisms for tissue regeneration and organogenesis

 
 

Research Achievement (Published Thesis) 【 display / non-display

  • Subject:Relationship between somatic mosaicism of Pax6 mutation and variable developmental eye abnormalities-an analysis of CRISPR genome-edited mouse embryos.

    Language:English

    Kind of Publishing:Academic Journal

    Journal name:Scientific Reports

    Publish date:2017.12

    Author:Yasue A, Kono H, Habuta M, Bando T, Sato K, Inoue J, Oyadomari S, Noji S, Tanaka E, Ohuchi H.

    Co-writerThe multiple authorship

    DOI:10.1038/s41598-017-00088-w

  • Subject:Expression analysis of Dickkopf-related protein 3 (Dkk3) suggests its pleiotropic roles for a secretory glycoprotein in adult mouse.

    Language:English

    Kind of Publishing:Academic Journal

    Journal name:Journal of Molecular Histology

    Publish date:2017.02

    Author:Inoue J, Fujita H, Bando T, Kondo Y, Kumon H, Ohuchi H.

    Co-writerThe multiple authorship

    DOI:10.1007/s10735-016-9703-2

  • Subject:Two opsin 3-related proteins in the chicken retina and brain: A TMT-type Opsin 3 is a blue-light sensor in retinal horizontal cells, hypothalamus, and cerebellum.

    Language:English

    Kind of Publishing:Academic Journal

    Journal name:PLoS ONE

    Publish date:2016.11

    Author:Kato M, Sugiyama T, Sakai K, Yamashita T, Fujita H, Sato K, Tomonari S, Shichida Y, Ohuchi H.

    Co-writerThe multiple authorship

    DOI:10.1371/journal.pone.0163925

  • Subject:TGF-β signaling in insects regulates metamorphosis via juvenile hormone biosynthesis

    Language:English

    Kind of Publishing:Academic Journal

    Journal name:Proceedings of the National Academy of Sciences of the United States of America , vol.113 (20) (p.5634 - 5639)

    Publish date:2016.05

    Author:Yoshiyasu Ishimaru,Sayuri Tomonari,Yuji Matsuoka,Takahito Watanabe,Katsuyuki Miyawaki,Tetsuya Bando*,Kenji Tomioka*,Hideyo Ohuchi*,Sumihare Noji,Taro Mito

    Co-writerThe multiple authorship

    DOI:10.1073/pnas.1600612113

  • Subject:Two UV-sensitive photoreceptor proteins, Opn5m and Opn5m2 in ray-finned fish with distinct molecular properties and broad distribution in the retina and brain

    Language:English

    Kind of Publishing:Academic Journal

    Journal name:PLoS One, PLoS ONE , vol.11 (5)

    Publish date:2016.05

    Author:Keita Sato*,Takahiro Yamashita,Yoshihiro Haruki,Hideyo Ohuchi*,Masato Kinoshita,Yoshinori Shichida

    Co-writerThe multiple authorship

    DOI:10.1371/journal.pone.0155339

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