Updated on 2024/04/22

写真a

 
GOTO Sachiko
 
Organization
Faculty of Health Sciences Associate Professor
Position
Associate Professor
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Degree

  • Doctor of Informatics ( Kyoto University )

  • Master of Science ( Osaka Kyoiku University )

Research Interests

  • 医用画像解析

  • Medical Image Analysis

Research Areas

  • Life Science / Radiological sciences

Education

  • Kyoto University    

    - 2004

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  • Kyoto University   情報学研究科   システム科学

    - 2004

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    Country: Japan

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  • Osaka Kyoiku University    

    - 2001

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  • Osaka Kyoiku University   教育学研究科   健康科学

    - 2001

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    Country: Japan

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  • 岡山大学医療技術短期大学部   医療技術学部   診療放射線技術学科

    - 1992

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    Country: Japan

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Research History

  • - 岡山大学保健学研究科 准教授

    2004

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  • - Associate Professor,Graduate School of Health Sciences,Okayama University

    2004

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Professional Memberships

Committee Memberships

  • 日本放射線技術学会   実行委員  

    2009   

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    Committee type:Academic society

    日本放射線技術学会

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Papers

  • Native myocardial T1 mapping using inversion recovery T1-weighted turbo field echo sequence.

    Katsuhiro Kida, Takamasa Kurosaki, Ryohei Fukui, Ryutaro Matsuura, Sachiko Goto

    Radiological physics and technology   2024.3

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    Language:English   Publishing type:Research paper (scientific journal)  

    This study proposes the use of the inversion recovery T1-weighted turbo field echo (IR-T1TFE) sequence for myocardial T1 mapping and compares the results obtained with those of the modified Look-Locker inversion recovery (MOLLI) method for accuracy, precision, and reproducibility. A phantom containing seven vials with different T1 values was imaged, thereby comparing the T1 measurements between the inversion recovery spin-echo (IR-SE) technique, MOLLI, and the IR-T1TFE. The accuracy, precision, and reproducibility of the T1-mapping sequences were analyzed in a phantom study. Fifteen healthy subjects were recruited for the in vivo comparison of native myocardial T1 mapping using MOLLI and IR-T1TFE sequences. After myocardium segmentation, the T1 value of the entire myocardium was calculated. In the phantom study, excellent accuracy was achieved using IR-T1TFE for all T1 ranges. MOLLI displayed lower accuracy than IR-T1TFE (p =0.016), substantially underestimating T1 at large T1 values (> 1000 ms). In the in vivo study, the first mean myocardial T1 values ± SD using MOLLI and IR-T1TFE were 1306 ± 70 ms and 1484 ± 28 ms, respectively, and the second were 1297 ± 68 ms and 1474 ± 43 ms, respectively. The native myocardial T1 obtained with MOLLI was lower than that of IR-T1TFE (p < 0.001). The reproducibility of native myocardial T1 mapping within the same sequence was not statistically significant (p = 0.11). This study demonstrates the utility and validity of myocardial T1 mapping using IR-T1TFE, which is a common sequence. This method was found to have high accuracy and reproducibility.

    DOI: 10.1007/s12194-024-00795-w

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  • Deep learning-based attenuation correction method in 99mTc-GSA SPECT/CT hepatic imaging: a phantom study Reviewed

    Masahiro Miyai, Ryohei Fukui, Masahiro Nakashima, Sachiko Goto

    Radiological Physics and Technology   2023.11

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer Science and Business Media LLC  

    DOI: 10.1007/s12194-023-00762-x

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    Other Link: https://link.springer.com/article/10.1007/s12194-023-00762-x/fulltext.html

  • Proposal for diagnosis using FLAIR image aimed for pediatric MELAS with recurrent stroke-like episodes on MRI system cannot take ASL imaging Reviewed

    Makoto Shimada, Tae Ikeda, Ryohei Fukui, Katsuhiro Kida, Ryutaro Matsuura, Takuya Akagawa, Sachiko Goto

    Egyptian Pediatric Association Gazette   71 ( 1 )   2023.11

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Springer Science and Business Media LLC  

    Abstract

    Background

    Arterial spin-labeling (ASL) imaging is currently the most useful method for diagnosing mitochondrial encephalomyopathy, lactic acidosis, and stroke-like attack syndrome (MELAS). However, ASL is often an optional feature of standard MRI systems. Therefore, not all MRI systems can perform ASL imaging. In contrast, fluid-attenuated inversion recovery (FLAIR) imaging is one of the common sequences in brain MRI because FLAIR imaging can be performed regardless of the specifications of the equipment. This study aimed to compare the diagnostic performance of quantitative analysis of signal intensity obtained from fluid-attenuated inversion recovery (FLAIR) images with ASL images for MELAS with recurrent stroke-like episodes (SLEs). A total of 68 cases with normal magnetic resonance imaging findings and 25 cases diagnosed MELAS with recurrent SLEs were included. We evaluated the frontal lobe and cuneus as target areas and compared the regional cerebral blood flow (rCBF) values obtained from ASL images with the normalized signal intensity (nSI) obtained from FLAIR images.

    Results

    The sensitivity and specificity for diagnosing MELAS from linear discriminant analysis (LDA) obtained from the rCBF values were 0.84 and 0.941, respectively, and those of nSI were 0.8 and 0.897, respectively. The area under the ROC curves (AUC) calculated from the receiver operating characteristic (ROC) curve analysis using rCBF values and nSI were 0.889 and 0.804, respectively.

    Conclusion

    Quantitative analysis using the signal intensity of the FLAIR image could have a diagnostic performance equivalent to that of rCBF values obtained from ASL images.

    DOI: 10.1186/s43054-023-00232-4

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    Other Link: https://link.springer.com/article/10.1186/s43054-023-00232-4/fulltext.html

  • 3D phase-sensitive inversion recovery sequence for intracranial vertebrobasilar artery dissection. Reviewed International journal

    Takuya Enoki, Katsuhiro Kida, Wataru Jomoto, Yusuke Kawanaka, Manabu Shirakawa, Masataka Miyama, Noriko Kotoura, Sachiko Goto

    Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia   118   52 - 57   2023.10

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    BACKGROUND: T1-weighted 3D turbo spin echo (T1W-3D-TSE) sequences with variable refocusing flip angle are commonly used to diagnose intracranial vertebrobasilar artery dissection (iVAD). However, magnetic susceptibility artifacts of the cavernous sinus may cause loss of the basilar and vertebral arteries. This study investigated the effectiveness of a 3D phase-sensitive inversion recovery (3D-PSIR) sequence in reducing magnetic susceptibility artifacts in the cavernous sinus, and its imaging findings for iVAD. METHODS: Twelve volunteers and eleven patients with iVAD were included. Magnetic resonance imaging (MRI) was performed using a 3.0-T MRI system. 3D-PSIR and T1W-3D-TSE sequences were used. Vessel wall defects and contrast-to-noise ratio (CNR) were evaluated. The MRI findings were visually evaluated. RESULTS: In the 3D-PSIR images, one volunteer (8 %) had vessel wall defects, and five (42 %) had vessel wall defects (p = 0.046) in the T1W-3D-TSE images. CNR was higher in 3D-PSIR images for vessel wall-to-lumen, whereas it was higher in T1W-3D-TSE images for vessel wall-to-CSF (p < 0.001). Visual evaluation revealed similar MRI findings between the two sequences. CONCLUSIONS: The 3D-PSIR sequence may be able to improve the vessel wall defects and achieve MRI findings comparable to those of the T1W-3D-TSE sequence in iVAD. The 3D-PSIR sequence can be a useful tool for the imaging-based diagnosis of iVAD.

    DOI: 10.1016/j.jocn.2023.10.008

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  • Influence of Two-Dimensional and Three-Dimensional Acquisitions of Radiomic Features for Prediction Accuracy Reviewed

    Ryohei Fukui, Ryutarou Matsuura, Katsuhiro Kida, Sachiko Goto

    Progress in Medical Physics   34 ( 3 )   23 - 32   2023.9

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    Authorship:Last author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:Korean Society of Medical Physics  

    DOI: 10.14316/pmp.2023.34.3.23

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  • Fundamental study for application of 3D phase-sensitive inversion recovery sequence to multiple sclerosis Reviewed

    Takuya Enoki, Wataru Jomoto, Katsuhiro Kida, Sachiko Goto, Noriko Kotoura

    Journal of the Japan Association of Radiologic Technologists   70 ( 6 )   580 - 587   2023.5

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    Language:English   Publishing type:Research paper (scientific journal)   Publisher:(公社)日本診療放射線技師会  

    本研究の目的は,3D PSIRを多発性硬化症へ応用するために,撮像パラメーターと脳組織コントラストの関係を明らかにすることである.ファントム実験で,TFE factor,shot interval,TIがコントラストに与える影響を検討した.TFE factorは30,shot intervalは1000msが採用された.健常ボランティアでTI(300-800ms)を変化させ,脳組織コントラストについて視覚評価を行った。TIを長くするとコントラストは向上した.3D-PSIRを多発性硬化症へ応用するには,TFE factorが30,shot intervalが1000msの場合,TIは700msが最適である.(著者抄録)

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  • Image Quality Assessment of Deep Learning Image Reconstruction in Torso Computed Tomography Using Tube Current Modulation Reviewed

    Kazuhiro Takeuchi, Yasuhiro Ide, Yuichiro Mori, Yusuke Uehara, Hiroshi Sukeishi, Sachiko Goto

    Acta Medica Okayama   77 ( 1 )   45 - 55   2023.2

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    DOI: 10.18926/AMO/64361

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  • Assessment of a New Elbow Joint Positioning Method Using Area Detector Computed Tomography Reviewed

    Takuya AKAGAWA, Ryohei FUKUI, Katsuhiro KIDA, Ryutaro MATSUURA, Makoto SHIMADA, Mitsuhiro KINOSHITA, Yoko AKAGAWA, Sachiko GOTO

    Acta Medica Okayama   2023

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  • Effect of Bead Device Diameter on Z-Resolution Measurement in Tomosynthesis Images: A Simulation Study Reviewed

    Ryohei Fukui, Miho Numata, Saki Nishioka, Ryutarou Matsuura, Katsuhiro Kida, Sachiko Goto

    Progress in Medical Physics   33 ( 4 )   1 - 9   2022.12

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  • Effect of Median Filter Processing on Measurement of Presampled Modulation Transfer Function using Edge Method in Digital Radiographic Systems Reviewed

    Kazuhiro Takeuchi, Masaki Asahara, Masatoshi Morimoto, Sachiko Goto

    Medical Imaging and Information Sciences   39 ( 2 )   30 - 37   2022.6

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  • The Effects of the Acquisition Condition of System Planar Sensitivity on Quantitative of SPECT Imaging Reviewed

    Kyoka Tanaka, Masahiro Nakashima, Sachiko Goto, Yoshihiro Takeda

    42 ( 2 )   139 - 145   2022.2

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  • Effect of the Number of Projected Images on the Noise Characteristics in Tomosynthesis Imaging Reviewed

    Ryohei Fukui, Ryutaro Matsuura, Katsuhiro Kida, Sachiko Goto

    Progress in Medical Physics   32 ( 2 )   50 - 58   2021.6

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    DOI: 10.14316/pmp.2021.32.2.50

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  • Image Evaluation of Free-breathing Navigator Echo and Triggered Cardiac-gated Delayed Reviewed

    Ryutaro Matsuura, Sachiko Goto, Shuhei Sato, Noriaki Akagi, Seiji Tahara

    Acta Med Okayama   72 ( 3 )   267 - 273   2018.6

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  • High spatial resolution MRA of renal arteries using contrast behavior between fat and water during transient phase before reaching a steady state Reviewed

    Katsuhiro Kida, Sachiko Goto, Yoshiharu Azuma

    EUROPEAN JOURNAL OF RADIOLOGY   81 ( 5 )   846 - 850   2012.5

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    Authorship:Corresponding author   Language:English   Publishing type:Research paper (scientific journal)   Publisher:ELSEVIER IRELAND LTD  

    Purpose: Our aim is high spatial resolution imaging of maximum intensity projection (MIP) images in renal magnetic resonance angiography (MRA) by constructing a protocol for acquiring three-dimensional volume data with isotropic voxels.
    Materials and methods: We eliminated water-selective excitation (WATS) and utilized effective contrast behavior between fat and water before reaching a steady state-that is, during the transient phase-to cover fat suppression by WATS. In a phantom study, the optimal flip angle was investigated under the "low-high Y" profile order using distilled water and baby oil to construct a protocol with isotropic voxels. Signal intensity, contrast, noise and signal-to-noise ratio were investigated to compare image qualities between the conventional and the constructed isotropic protocols. In a clinical study, three radiologists and two radiological technologists visually evaluated clinical images of 20 volunteers for spatial resolution, contrast and overall reader confidence in two protocols.
    Results: We constructed an isotropic protocol with voxel dimensions of 0.78 mm x 0.78 mm x 0.78 mm at a flip angle of 90 degrees. We maintained the scan time but enlarged the x-y pixel dimensions from 0.59 mm x 0.59 mm to 0.78 mm x 0.78 mm and shortened image height from 48 mm to 42.9 mm. Data from the phantom study were worse in the isotropic protocol than in the conventional protocol. However, overall reader confidence in the clinical images was significantly better in the isotropic protocol than in the conventional protocol (p &lt; .001).
    Conclusion: Our study indicated the value of addressing high spatial resolution imaging of MIP images for renal MRA by constructing an isotropic protocol. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

    DOI: 10.1016/j.ejrad.2011.02.031

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  • 頭部MRIのT1強調画像における各種Contrast to Noise Ratio (CNR) 算出法の比較 Reviewed

    木田勝博, 後藤佐知子, 東 義晴, 梶谷 努

    日本放射線技師会雑誌   59 ( 702 )   81 - 86   2012

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  • Computerized Estimation of a Percent Glandular Tissue Composition in Computed Radiography Mammography Reviewed

    TSUJITA Naoko, GOTO Sachiko, AZUMA Yoshiharu, SHIRAISHI Junji

    Jpn. J. Radiol. Technol.   67 ( 12 )   1540 - 1547   2011

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    Language:Japanese   Publisher:Japanese Society of Radiological Technology  

    Measurement of a percent glandular tissue composition (%GTC) is important in terms of the estimation of individual patient exposure dose and the prediction of malignancy, and thus a number of reports for estimating %GTC by use of a mammogram have been published. In this study, we propose a method for estimating individual %GTC by use of computed radiography (CR) mammograms. By employing breast-equivalent phantoms that are able to create breast phantom images with various combinations of fat and glandular tissue, as well as the thickness of whole breast, we determined a reference table for converting an each pixel value on CR mammography to the glandular tissue ratio. Therefore, the %GTC for individual breast was estimated by averaging glandular tissue ratio for a whole region. The clinical image data set that consisted of 49 CR mammograms were used for estimating %GTC. A paired comparison method for determining subjective ranking of the degree of breast density was employed in order to demonstrate the validity of our method. The results indicate that the average estimated %GTC was 35.0% (ranged from 12.0% to 67.0%) and they had a increased correlation with the ranking of those obtained by observer test. Therefore, it was suggested that our proposed method would be utilized for estimating the %GTC in objective manner.

    DOI: 10.6009/jjrt.67.1540

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  • 頚部MRI脂肪抑制T1強調画像における磁化率アーチファクト軽減補助具(Sat-Pad)の作製 Reviewed

    木田勝博, 後藤佐知子, 梶谷努, 東義晴

    岡山赤十字病院医学雑誌   22 ( 1 )   27 - 30   2011

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    Language:Japanese   Publisher:岡山赤十字病院医学雑誌編集委員会  

    MRIにおいて軟部組織と空気境界面は、磁化率変化によるアーチファクトが起こりやすい。通常、MRIでは脂肪抑制法が頻繁に用いられるが、磁化率の変化は脂肪抑制のムラを引き起こす。その脂肪抑制ムラは、解剖学的な形状のために、頸部で頻繁に生じる。本研究では、磁化率変化を軽減する補助具(Sat-Pad)の作製を試みた。(著者抄録)

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  • Accuracy of Measurement of Radiochromic Film Density for High-energy X-rays Reviewed

    AOYAMA HIDEKI, AZUMA YOSHIHARU, GOTO SACHIKO, TAHARA SEIJI, UNO HIROFUMI, INAMURA KEIJI, KADOHISA SHIGEFUMI, NAKAGIRI YOSHITADA, KANAZAWA SUSUMU, SUMIMOTO TETSUHIRO, AZUMA MASAMI

    Japanese Journal of Radiological Technology   60 ( 11 )   1533 - 1542   2004

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    Language:Japanese   Publisher:Japanese Society of Radiological Technology  

    Radiochromic film (RC-film) is of great interest as a film-type dosimeter for radiation oncology applications. We present a two-dimensional image-based evaluation of the measurement accuracy of a commercial RC-film product (Gafchromic MD-55-2 film, ISP TECHNOLOGIES, Inc.) by using a commercial Laser Densitometer (Model 1710, Computerized Medical Systems, Inc.) as an optical density imaging system. The coefficient of variation of the density (pixel-value) in one sample was approximately 3% to 11 % at 3 Gy or less, and 3% or less at 4 to 60 Gy. Although the coefficient of variation between three samples at the same dose was about 14% at 1 Gy, it decreased as the dose increased, reaching several percent. In 1 to 6 Gy samples, geometric imaging artifacts [interference (moire) patterns] were observed, and it was found that scan-sampling pitch influenced the accuracy of measurement of the density of the sample. To improve the accuracy of density measurement, sufficient knowledge about characteristic features of the density measuring system is essential.

    DOI: 10.6009/jjrt.KJ00003326577

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  • 放射線治療時の治療部外散乱被曝線量に関する研究 Reviewed

    川辺睦, 中桐義忠, 小橋一輝, 安村直樹, 山下剛央, 後藤佐知子, 丸山敏則, 杉田勝彦

    岡山大学医学部保健学科紀要   2003

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  • 線量測定用 GAFCHROMIC XR TYPE T の特性 Reviewed

    窪津真理子, 中桐義忠, 氏福亜矢子, 谷口友季子, 八谷美穂, 東義晴, 後藤佐知子, 丸山敏則, 青山英樹, 田原誠司, 稲村圭司, 渡邊敏充, 杉田勝彦

    岡山大学医学部保健学科紀要   2003

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  • Estimating AverageGlandular Dose by Measuring Glandular Rate in Mammograms Reviewed

    Sachiko Goto, Yoshiharu Azuma, Tetsuhiro Sumimoto, Shigeru Eiho

    MEDICAL IMAGING TECHNOLOGY   21 ( 5 )   369 - 376   2003

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    Authorship:Lead author   Language:English  

    DOI: 10.11409/mit.21.369

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  • Procedure of Giving Barium Meal and Foaming Agent : Its Swallowing Ease and Outflow Reviewed

    SHIBUYA KOICHI, MIYAKE KOICHI, OEDA TSUGUTO, FUJI TERUMASA, NAKAGIRI YOSHITADA, AZUMA YOSHIHARU, MARUYAMA TOSHINORI, GOTO SACHIKO, SUGITA KATSUHIKO, HIRAKI YOSHIO

    Japanese Journal of Radiological Technology   57 ( 4 )   440 - 443   2001

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    Language:Japanese   Publisher:Japanese Society of Radiological Technology  

    Rates of Flow of barium meal into the bowel and ease of swallowing a barium meal and foaming agent were investigated according to the procedure of administration, in order to study the timing of adding the foaming agent. In group medical examinations, the flow rates of barium meals of 100 examinees given a barium meal followed by a foaming agent were compared with those of the same examinees given the foaming agent first. Parasympatholytic agents were not administered in this study. When the foaming agent was given before the barium meal, the flow rate of the barium meal into the bowels was 44.0%. In contrast, when the foaming agent was given after the barium meal, the rate was 78.0%. A total of 67.3% of 101 Volunteers given the foaming agent and the barium meal twice in the reverse order answered that it was easier to swallow the barium meal first. When a parasympatholytic agent is not given, it is better to give the foaming agent first, even though it is more difficult to swallow the barium meal after the foaming agent, because it is most important in examination of the stomach that the barium meal does not flow out into the bowel.

    DOI: 10.6009/jjrt.KJ00001357562

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  • A study of x-rays protection in a hip-joint radiography examination Reviewed

    11 ( 2 )   59 - 64   2001

  • 股関節X線撮影における女性生殖腺の防護について Reviewed

    中桐義忠, 丸山敏則, 後藤佐知子, 谷本江利子, 田村恵里, 鳥居史子, 渋谷光, 東義晴

    岡山県放射線技師会会誌   2001

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  • Property of single screen/single-emulsion film system : The influence of X-ray energy by air attenuation Reviewed

    MARUYAMA Toshinori, GOTO Sachiko, AZUMA Yoshiharu, NAKAGIRI Yoshitada, SUMIMOTO Tetsuhiro, YAMAMOTO Hideki

    IEICE technical report.   101 ( 434 )   1 - 8   2001

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    Authorship:Corresponding author   Language:Japanese   Publisher:The Institute of Electronics, Information and Communication Engineers  

    It is difficult to obtain accurate characteristic curves of single/screen single-emulsion film systems for mammography at low X-ray energies because of air attenuation. Then we measured the photoluminescence of screen by using two kinds of excitation X-ray energies and investigated the influence of X-ray energy in screen for the mammographic system. And we tried to correct air attenuation acculately for energy spectra varying continuously to obtain the characteristic curves for mammographic system with mammogaraphic unit. Furthermore, the characteristic curves obtained by inverse square sensitometry with general radiographic unit were compared with the characteristic curves obtained the correcting inverse square sensitometry with mammographic unit. Consequently, it is suggested that was possible to obtain characteristic curves for single-screen single-emulsion film systems when chosing X-ray energies without the influence of air sttenuation.

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  • Breast dosimetry system in screen/film mammography Reviewed

    Goto Sachiko, Azuma Yoshiharu, Maruyama Toshinori, Nakagiri Yoshitada, Takeda Yoshihiro, Sugita Katsuhiko, Kadohisa Shigefumi

    10 ( 2 )   99 - 106   2000

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  • Examination of Procedure Used in Giving Barium Meal and Foaming Agent Reviewed

    SHIBUYA KOICHI, OEDA TSUGUTO, MIYAKE KOICHI, TANDANI NOBUYOSHI, NAKAGIRI YOSHITADA, AZUMA YOSHIHARU, MARUYAMA TOSHINORI, GOTO SACHIKO, SUGITA KATSUHIKO, HIRAKI YOSHIO

    Japanese Journal of Radiological Technology   56 ( 4 )   605 - 609   2000

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    Language:English   Publisher:Japanese Society of Radiological Technology  

    Two kinds of gastric images of 85 examinees were compared in order to study the procedure of giving barium meal and forming agents The more recent images were obtained with examinees given a barium meal followed by a forming agent, whereas the other images were of the same examinees obtained the previous year, with the foaming agent given before the barium meal. Results showed that when the barium meal was given first, the mucous membrane of the stomach was imaged better. In contrast, when the forming agent was given first, sodium tartrate, derived from the foaming agent, was considered to cover the mucous membrane and physically to prevent the barium meal from clinging to the membrane.

    DOI: 10.6009/jjrt.KJ00001356895

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  • Application of Extended-cycle Process to Mammography : Effect on Improvement of Visibility Reviewed

    MARUYAMA Toshinori, GOTO Sachiko, AZUMA Yoshiharu, NAKAGIRI Yoshitada, SUGITA Katsuhiko

    Japanese Journal of Radiological Technology   56 ( 11 )   1339 - 1347   2000

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    Authorship:Corresponding author   Language:Japanese   Publisher:Japanese Society of Radiological Technology  

    We applied an extended-cycle process, in which the processing time is longer than the manufacturer's recommendation, to a low-speed, high-resolution system in mammography and investigated to what extent sharpness, contrast, and speed would be maintained or increased and whether this process could be applied clinically. In this study, a single-screen/single-emulsion film, Konica M-100/CM-H, was used in the lowspeed, high-resolution system, and M-200/CM-H was employed for comparison. Developing temperatures of 30, 32, and 34 degrees centigrade and a processing time of 210 seconds were selected as conditions of the extended-cycle process. M-100/CM-H with the extended-cycle process(M-100/E system)and M-200/CM-H with the standard-cycle process were compared at 34 and 90 seconds(M-200 system)in terms of contrast, speed, modulation transfer function(MTF), and Wiener spectrum(WS). In addition, the visibility of mammograms obtained using an RMI 165 phantom was evaluated by the method of paired comparisons. In the comparison of the M-200 system with the M-100/E system at 34 and 210 seconds, the speed was almost equal and the average gradient and MTF value at 2.5 cycles/mm increased about 20% and 8%, respectively. Ws was higher due to the increase in quantum mottle with increases in the average gradient and MTF. In the scale of the method of paired comparisons, M-100/E systems showed better results. Moreover, entrance skin exposure in air of the M-100/E system at 34 and 210 seconds was almost equal to that of the M-200 system. These results suggested that it was possible to improve visibility by the extended-cycle process in a low-speed, high-resolution system.

    DOI: 10.6009/jjrt.KJ00001357361

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  • Basic Study of the Effect of the Extended-cycle Process on Mammographic Screen/Film Systems: Granularity Reviewed

    Azuma Yoshiharu, Goto Sachiko, Maruyama Toshinori, Nakagiri Yoshitada, Sugita Katsuhiko

    Japanese Journal of Radiological Technology   56 ( 7 )   937 - 945   2000

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    With single-emulsion films like those used in screen/film mammography, if the developing temperature is higher and/or the processing time is longer than recommended (i.e., extended-cycle process), film speed and/or film contrast are effectively increased. However, it can also be expected that radiographic noise will be increased by the extended-cycle process. Therefore, film graininess and radiographic mottle were investigated with standard-and extended-cycle processes in four single-screen/single-emulsion film systems for mammography, the Konica M-150/New CM, Fuji UM MAMMO Fine/UM-MA HC, Kodak Min-R2000/Min-R2000, and Kodak Min-R Medium/Min-R M. Investigation was carried out by measurement of the Wiener spectrum (WS). Results showed that the WS of film graininess increased in all films. The increase was greatest in Min-R M, and the rate of increase at 2.0 cycles/mm was 1.67 or more. The film showing the smallest increase was UM-MA HC, for which the rate of increase was 1.03-1.21. There were cases in which the spatial frequency at a 50 percent contribution rate of film graininess to radiographic mottle changed to a low spatial frequency. When only the increase in WS of radiographic mottle was examined, the increase was greatest in Min-R Medium/Min-R M, and the rate of increase at 2.0 cycles/mm was 1.65 or more. Min-R2000/Min-R2000 showed the least increase, and the rate of increase was 1.12-1.24. Increases in WS values were larger at 0.1-0.5 cycle/mm than at 2.0 cycles/mm when investigating the influence of trend using film graininess, and roller marks and so on could not be specified as a cause.

    DOI: 10.6009/jjrt.KJ00001357002

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  • The influence of air attenuation in characteristic curve for mammographic screen-film system Reviewed

    10 ( 2 )   91 - 98   2000

  • 撮影条件からの腹部X線被曝線量の算定-岡山県下の現況- Reviewed

    中桐義忠, 丸山敏則, 後藤佐知子, 東 義晴, 渋谷光一, 井上龍也, 門久繁文, 森岡泰樹

    岡山県放射線技師会会誌   1999

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  • Improvement of image quality on mammographic screen-film system by extended-cycle process Reviewed

    Goto Sachiko, Maruyama Toshinori, Azuma Yoshiharu, Nakagiri Yoshitada, Takeda Yoshihiro, Sugita Katsuhiko, Kimura Fumie, Kadohisa Shigefumi

    9 ( 2 )   83 - 90   1999

  • Measurement of Film Graininess on Mammographic Films Reviewed

    GOTO SACHIKO, AZUMA YOSHIHARU, MARUYAMA TOSHINORI, NAKAGIRI YOSHITADA, SUGITA KATSUHIKO

    Japanese Journal of Radiological Technology   55 ( 11 )   1115 - 1121   1999

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    Film graininess can be measured by providing air spaces between the screen and film in the screen-film system. In this study, the necessary air spaces were investigated to measure mammographic film graininess by using a mammography unit at the low tube voltage of 28 kV. Wiener spectra were measured with the screen held 1, 3, 6, 9,15, 21, and 30 mm from the film at densities of 0.8 and 1.3. Konica New CM film with a Konica M-150 screen was employed in this investigation. Results showed that Wiener spectral values were almost constant at densities of 0.8 and 1.3 when the air spaces were 9 mm or more. That is, it was considered that film graininess was evaluated independently by blurring quantum mottle, and 15 mm air spaces were used to provide a safety margin. Furthermore, film graininess of three mammographic films, Fuji UM-MA HC (with a Fuji UM MAMMO Fine screen), Kodak Min-R 2000 (with a Kodak Min-R 2000 screen), and Kodak Min-R M(with a Kodak Min-R Medium screen)were measured with 15 mm air spaces. Min-R 2000 film had the lowest Wiener spectral values for film graininess at low spatial frequencies.

    DOI: 10.6009/jjrt.KJ00000921418

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  • Patient Dose on the Radiological Diagnosis of Abdomen - The Situation of Patient nose at Hospitals in Okayama Prefecture - Reviewed

    20 ( 20 )   17 - 21   1998

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  • The Influence of Film Processing Temperature and Time on Mammographic film Characteristics Reviewed

    Maruyama Toshinori, Goto Sachiko, Azuma Yoshiharu, Nakagiri Yoshitada, Shibuya Koichi, Sugita Katsuhiko, Takeuchi Tomoyuki, Honda Mitsugi, Yoshida Akira

    Vol.8 No.2 ( 2 )   121 - 129   1998

  • Basic Study of the Effect of the Extended-cycle Process on Mammographic Films : Contrast and Relative Speed

    MARUYAMA TOSHINORI, GOTO SACHIKO, AZUMA YOSHIHARU, NAKAGIRI YOSHITADA, SUGITA KATSUHIKO

    Japanese Journal of Radiological Technology   53 ( 11 )   1697 - 1704   1997

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    The effectiveness of the extended-cycle process, in which processing time is longer than the manugacturer's recommendation, was investigated using four mammographic films, Konica New CM, Fuji UM-MA HC, Kodak Min-R 2000, and Kodak Min-R M, Fuji UR-2, a double-emulsion film, was used as a control. The sensitometric strips exposed by a sensitometer were processed in different combinations of developing temperatures ranging from 28 to 36℃, processing times from 45 to 210 sec chemicals, Konica XD-90C, Fuji RD-5 and Kodak RP X-Omat. Those characteristics(average gradient, relative speed, base plus fog)obtained from characteristic curves were evaluated for the different developing temperatures, times and chemicals. Fuji UR-2 was scarcely affected, while mammographic films were greatly affected in the different combinations without an increase in base plus fog. For New CM, UM-MA HC and Min-R M, the average gradient and relative speed increased as developing temperature increased and developing time was extended, but the increases were limited with the combination of 36℃ and 210 sec for New CM and UM-MA HC. For Min-R 2000, the average gradient was almost constant, and the relative speed increased like the other three mammographic films. Changes in average gradient and relative speed due to chemical variations showed increases or decreases from 6% to 9% compared with Konica chemical. These results suggested that the extended-cycle process for the above mammographic films has the possibility to contribute to dose reduction and advancement of contrast on mammography.

    DOI: 10.6009/jjrt.KJ00001355420

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  • 302 Effect of Extended-cycle Processing on Mammographic Films

    Goto Sachiko, Maruyama Toshinori, Azuma Yoshiharu, Nakagiri Yoshitada, Sugita Katsuhiko, Yoshida Akira

    Japanese Journal of Radiological Technology   53 ( 8 )   1174 - 1174   1997

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    DOI: 10.6009/jjrt.KJ00001356145

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  • X線撮影領域での体内線量分布の測定 Reviewed

    高田義明, 中桐義忠, 稲村圭司, 栞原菊次, 升谷敬彦, 田原誠治, 宇野弘文, 三上泰隆, 東 義晴, 渋谷光一, 後藤佐知子, 杉田勝彦

    日本放射線技師会雑誌   41 ( 5 )   524 - 529   1994.5

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  • A Computer-Aided System for Image Diagnosis of the Temporomandibular Joint Tomograms. Quantification of the Condylar Translation during Maximum Jaw Opening. Reviewed

    13 ( 2 )   223 - 231   1994

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  • A Computer-Aided System for Image Diagnosis of the Temporomandibular Joint Tomograms. Auto-binaryzation and Analysis of the Tomograms. Reviewed

    12 ( 2 )   265 - 272   1993

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Books

  • 診断X線の基礎 物理法則と臨床応用

    オーム社  2004 

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  • CT減弱補正におけるCT撮影条件が骨SPECTの定量値に与える影響

    中澤健吾, 中嶋真大, 後藤佐知子, 竹田芳弘, 本田貢

    第17回 中四国放射線医療技術フォーラム   62 - 62   2021.12

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  • 高吸収体がトモシンセシス画像ノイズ測定に与える影響

    福井良性, 太田雄大, 沼田美保, 谷口菜摘子, 西岡早紀, 松浦龍太郎, 木田勝博, 後藤佐知子, 本田貢, 平木隆夫

    第17回 中四国放射線医療技術フォーラム   62 - 62   2021.12

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  • Reduction of scan time for phase image of 3T magnetic resonance imaging to detect of calcification

    Tomoka Doi, Katsuhiro Kida, Sachiko Goto, Yoshiharu Azuma, Takushi Kawashima, Takahiko Yokote, Tsutomu Kajitani

    2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC)   2012.10

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  • Exploration of brain activations by passive hand movements and subject’s intention based on Kawahira method using 3T-fMRI

    Takushi Kawashima, Katsuhiro Kida, Satoshi Kuwahara, Takahiko Yokote, Tomoka Doi, Sachiko Goto, Yoshiharu Azuma

    2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record   2012

  • Detection of Calcification in Human Breast Using Phase Image of Magnetic Resonance Imaging

    Katsuhiro Kida, Sachiko Goto, Tomoka Doi, Tsutomu Kajitani, Yoshiharu Azuma

    2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record   2012

  • Observation of activation brain areas in response to the stimulation by the right hand movement of Kawahira method using fMRI

    Takahiko Yokote, Katsuhiro Kida, Satoshi Kuwahara, Takushi Kawashima, Tomoka Doi, Sachiko Goto, Yoshiharu Azuma

    2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record   2012

  • Observation of activation brain areas in response to the stimulation by the right hand movement of Kawahira method using fMRI

    Takahiko Yokote, Katsuhiro Kida, Satoshi Kuwahara, Takushi Kawashima, Tomoka Doi, Sachiko Goto, Yoshiharu Azuma

    2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record   2012

  • Exploration of brain activations by passive hand movements and subject's intention based on Kawahira method using 3T-fMRI

    Takushi Kawashima, Katsuhiro Kida, Satoshi Kuwahara, Takahiko Yokote, Tomoka Doi, Sachiko Goto, Yoshiharu Azuma

    2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record   2012

  • Detection of Calcification in Human Breast Using Phase Image of Magnetic Resonance Imaging

    Katsuhiro Kida, Sachiko Goto, Tomoka Doi, Tsutomu Kajitani, Yoshiharu Azuma

    2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record   2012

  • 3.0-T MRIにおける拡散強調像の評価

    木田勝博, 後藤佐知子, 黒崎貴雅, 梶谷努, 東義晴

    岡山赤十字病院医学雑誌   23   2012

  • Evaluation of the ability of nonlinear noise reduction filter to the low-contrast object in Multi-Detector Row Computed Tomography using a digital phantom and power spectrum

    S. Kondo, S. Goto, Y. Hyodo, T. Maruyama, Y. Azuma, R. Matsuura, K. Inamura

    2011 IEEE International Conference on Imaging Systems and Techniques, IST 2011 - Proceedings   160 - 164   2011

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    We propose a quantitative method to evaluate the ability of adaptive image filters for reducing noise to low-contrast objects in Multi-Detector Row Computed Tomography (MDCT). The digital phantom for evaluating the ability of a nonlinear noise reduction filter to a low-contrast object in a MDCT image was produced. The digital phantom consists of a water phantom image of MDCT and a bar pattern with a known contrast and spatial frequency. The edge-preserving adaptive filter for selectively eliminating noise in low-dose scanning known as the Quantum Denoising System developed by Toshiba Medical Systems was chosen as a nonlinear noise reduction filter for this paper. In this paper, two non-linear noise reduction filters, Q1 and Q2 in QDS were employed. By analyzing the power spectrum (PS) of a digital phantom, the filter performance as regards the contrast and spatial frequency of an object was investigated. The contrast-to-noise ratio from PS could express the feature of the filter briefly. That is, the validity of a filter can be shown based on the combined information of the contrast and spatial frequency of an object. Probably, this simple method will contribute to evaluating various noise reduction filters efficiently. © 2011 IEEE.

    DOI: 10.1109/IST.2011.5962206

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  • Detection of calcification using high-pass filtered phase image in magnetic resonance imaging for breast cancer screening

    Katsuhiro Kida, Tsutomu Kajitani, Sachiko Goto, Yoko Tsuji, Toshinori Maruyama, Yoshiharu Azuma

    2011 IEEE International Conference on Imaging Systems and Techniques, IST 2011 - Proceedings   224 - 228   2011

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    To achieve detection of calcifications using magnetic resonance imaging (MRI) for breast cancer screening, we investigated combinations of an echo time (TE) and a high-pass filter size on phase images using a breast phantom. The breast phantom was made from gel area of 0.1 mmol/L gadopentetate dimeglumine and 2.0 wt% agar containing imitation calcifications to simulate calcification in the breast. To use the phase image for calcification assessment, optimization of TE was required since a difference of phase is enhanced at sufficiently long TE. However, longer TE tends to increase the static field inhomogeneity effects. To remove the static field inhomogeneity effects, we employed a high-pass filter processing. Then, several different filter sizes were tested to optimize the visualization of calcification. TE of 48 msec had the highest contrast between imitation calcifications and gel area. The high-pass filter size of 6464 pixels was able to remove efficiently the background phase effects. The high-pass filtered phase image was able to show imitation calcifications as hyperintense areas. Although the limit of detection of imitation calcifications was 1.0 mm, it suggests a possibility that the high-pass filtered phase image is able to use for breast cancer screening and diagnosis without pain by compression or the use of ionizing radiation. © 2011 IEEE.

    DOI: 10.1109/IST.2011.5962192

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  • フラットベッドスキャナの3カラーチャンネルすべてを用いるラジオクロミックフィルム線量測定(第66回総会学術大会放射線防護・管理関連演題発表後抄録)

    大山 博信, 青山 英樹, 東 義晴, 後藤 佐知子, 丸山 敏則, 稲村 圭司

    放射線防護分科会会誌   ( 31 )   31 - 31   2010.10

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  • Optimization of Combination of Voxel Size and Flip Angle by Visual Evaluation for Renal Magnetic Resonance Angiography without a Contrast Agent

    K. Kida, S. Goto, Y. Azuma

    IFMBE Proceedings   364 - 367   2009.9

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    DOI: 10.1007/978-3-642-03879-2_103

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  • The single emission spectrum densitometry for radiochromic films by flat-bed document scanner with transparency unit employing light emitting diode

    Yoshiharu Azuma, Hideki Aoyama, Sachiko Goto

    2008 IEEE INSTRUMENTATION AND MEASUREMENT TECHNOLOGY CONFERENCE, VOLS 1-5   294 - 298   2008

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    We developed an infrared flat-bed scanner with a transparency unit (IR-4000, iMeasure, Inc.) in order to increase the sensitivity of the measuring density of Radiochromic film, Gafchromic film EBT model. Radiochromic film hay been used for many years as a two-dimensional radiation detector for dosimetry in radiotherapy. One of the commercially available Radiochromic films today is the Gafchromic film EBT model (EBT) manufactured by ISP (International Speciality Products, Wayne, NJ). EBT has the absorption spectrum with a maximum absorption band centered at 636 nm Consequently the response of EBT will be enhanced by measuring with a red light. The transparency unit of IR-4000 for EBT hay a light emitting diode (LED) with a peak wavelength of 630 nm, and was produced by replacing a white light in the transparency unit for the flat-bed scanner (ES-2200, Seiko Epson Corp) with the LEDs. IR-4000 could improve the sensitivity for EBT in all dose ranges However, we had to consider the methods for decreasing noise. We examined for IR-4000 how to keep the high sensitivity and reduce noise. Multiple scans and the reduction of the image resolution by pixel averaging, which was effective in noise reductio?; were employed. IR-4000 is a useful densitometry device to GAFs since optional transparency units which have various single emission spectra are prepared

    DOI: 10.1109/IMTC.2008.4547049

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  • Magnetic Resonance Angiography of Renal Arteries using Contrast Behavior between Water and Fat during the Transient Phase of Steady State of Signal on Balanced Turbo Field Echo Sequence

    Katsuhiro Kida, Sachiko Goto, Yoshiharu Azuma

    2008 IEEE Instrumentation and Measurement Technology Conference   1223 - 1228   2008

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  • Detectibility of renal artery under high resolution MR angiography using steady state free precession sequence in phantom study

    Katsuhiro Kida, Yoshiharu Azuma, Sachiko Goto, Tsutomu Kajitani, Tetsuhiro Sumimoto

    World Congress on Medical Physics and Biomedical Engineering 2006   1591 - 1594   2006.8

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    DOI: 10.1007/978-3-540-36841-0_390

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  • Relations Between Accuracy of Vessel Measurement and Physical Image Quality Characteristics inMulti-detector CT Scanner

    Y. Azuma, T. Akagawa, H. Hamaguchi, S. Goto, T. Sumimoto

    Instrumentation and Measurement Technology   2006

  • Detectibility of renal artery under high resolution MR angiography using steady state free precession sequence in phantom study

    Katsuhiro Kida, Yoshiharu Azuma, Sachiko Goto, Tsutomu Kajitani, Tetsuhiro Sumimoto

    the World Congress on Medical Physics and Biomedical Engineering 2006(WC2006)   2006

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  • Development of infrared flat-bed scanner with transparency unit employing light emitting diode for Gafchromic EBT film

    Hideki Aoyama, Yoshiharu Azuma, Sachiko Goto, Hirofumi Hato, Tetsuhiro Sumimoto

    the World Congress on Medical Physics and Biomedical Engineering 2006(WC2006)   2006

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  • Increasing the sensitivity of the dosimetry system for high energy x-rays, using Gafchromic EBT film and a flat-bed scanner with sharp cut

    Hirofumi Hato, Hideki Aoyama, Yoshiharu Azuma, Sachiko Goto, Tetsuhiro Sumimoto

    the World Congress on Medical Physics and Biomedical Engineering 2006(WC2006)   2006

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  • High accuracy measuring method of absorbed dose using Radiochromic Film and a micro-densitometer for high-energy x-rays

    Hideki Aoyama, Yoshiharu Azuma, Sachiko Goto, Tetsuhiro Sumimoto

    SIGNAL ANALYSIS, MEASUREMENT THEORY, PHOTO-ELECTRONIC TECHNOLOGY, AND ARTIFICIAL INTELLIGENCE, PTS 1 AND 2   6357   2006

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    Radiochromic film has been applied to mapping of dose distributions in radiation therapy. However, this particular RCF product suffers from intrinsic nonuniform response. In this study, we have carefully measured the nonuniformity of unirradiated RCF, and the response of irradiated RCF in pixel-to-pixel as function of various absorbed doses, in order to create a method of predicting the error of irradiated, unirradiated RCF.

    DOI: 10.1117/12.716968

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  • Analysis of influence of digital mammography on the individual average glandular dose against screen-film system

    Y. Azuma, S. Goto, T. Sumimoto, Y. Takeda

    the World Congress on Medical Physics and Biomedical Engineering 2006(WC2006)   2006

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  • Estimation of breast density on digital mammograms

    Sachiko Goto, Yoshiharu Azuma, Hideki Aoyama, Tetsuhiro Sumimoto

    SIGNAL ANALYSIS, MEASUREMENT THEORY, PHOTO-ELECTRONIC TECHNOLOGY, AND ARTIFICIAL INTELLIGENCE, PTS 1 AND 2   6357   2006

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    We built an estimation system of individual breast density from digital mammograms by using breast tissue equivalent phantoms that are able to change the mixture ratio of adipose and glandular tissue and the thickness. The method was compared with a visual assessment of breast density by the radiologists as a gold standard. The clinical image data set that consisted of 49 mammograms of 21 patients were analyzed. The average of the estimated glandular rate was 35.0%, while varying from 12.0% to 67.0%. This system can apply in clinical practice such as the visual estimation of breast density.

    DOI: 10.1117/12.716998

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  • Analysis of BGA defects by tomographic images

    T. Sumimoto, T. Maruyama, Y. Azuma, S. Goto, M. Mondou, N. Furukawa, S. Okada

    SIGNAL ANALYSIS, MEASUREMENT THEORY, PHOTO-ELECTRONIC TECHNOLOGY, AND ARTIFICIAL INTELLIGENCE, PTS 1 AND 2   6357   2006

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    To improve the cost of performance in manufacturing IC packages, it is required to inspect BGA defects in the online process. The problems of image analysis for the detection of defects are the detection accuracy and image processing time according to a line speed of production. Using the X-ray penetration equipment, we have captured images of an IC package to search an abnormal BGA. To get design data for the development of the inspection system, which can be used easily in the surface mount process, we tried to capture the tomographic images utilizing the latest imaging techniques.

    DOI: 10.1117/12.716986

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  • 放射線治療におけるGAFクロミックフィルム用線量分布測定装置の開発

    東 義晴, 後藤佐知子

    平成16年度〜平成17年度科学研究費補助金( 基盤研究(C)(2))研究成果報告書   2006

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  • Measurement of Breast Density on DigitalMammograms

    Sachiko Goto, Yoshiharu Azuma, Tetsuhiro Sumimoto, Yoshihiro Takeda, Naoko Tsujita, Shigefumi Kadohisa

    Instrumentation and Measurement Technology   2006

  • High Accuracy Measurement System of Absorbed Dose Using Combination of Radiochromic Film and Micro-Densitometer for Radiation Therapy

    Hideki Aoyama, Yoshiharu Azuma, Sachiko Goto, Hirofumi Hato, Tetsuhiro Sumimoto

    Instrumentation and Measurement Technology   2006

  • Head multidetector-row CT angiography with low kV settings:improved vessel enhancement and noise reduction in phantom studies

    Hiroyuki Hamaguchi, Takuya Akagawa, Youji Kimura, Koutarou Hashimoto, Kazutoshi Tsunou, Sachiko Goto, Yoshiharu Azuma

    the World Congress on Medical Physics and Biomedical Engineering 2006(WC2006)   2006

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  • A-4-26 Improvement of Detectivity of Renal Artery in Non-contrast MR Angiography

    Kida Katsuhiro, Kajitani Tsutomu, Sumimoto Tetsuhiro, Azuma Yoshiharu, Gotoh Sachiko

    Proceedings of the Society Conference of IEICE   2005   95 - 95   2005.9

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    Language:Japanese   Publisher:The Institute of Electronics, Information and Communication Engineers  

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  • Influence of image quality characteristics on the accuracy of vessel measurement using Multi-detector CT scanner

    T. Akagawa, Y. Azuma, S. Goto, T. Sumimoto

    The Society of Instrument and Control Engineers   2005

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  • Tomographic Image Analysis for Detection of Defects at BGA

    T. Sumimoto, T. Maruyama, Y. Azuma, S. Goto, M. Mondou, N. Furukawa, S. Okada

    The Society of Instrument and Control Engineers   2005

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  • Estimation of Breast Density on Digital Mammograms

    N. Tsujita, S. Goto, Y. Azuma, T. Sumimoto, S. Kadohisa

    The Society of Instrument and Control Engineers   2005

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  • Improvement in Measuring Accuracy of Radiochromic Film Density for High-Energy X-Rays

    H. Aoyama, Y. Azuma, S. Goto, T. Sumimoto

    The Society of Instrument and Control Engineers   2005

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  • X-ray image analysis of defects at BGA for manufacturing system reliability

    T Sumimoto, T Maruyama, Y Azuma, S Goto, M Mondou, N Furukawa, S Okada

    Advanced Reliability Modeling   507 - 514   2004

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    This paper deals with the image analysis of defects at BGA for the reliability in PC boards by using X-ray imaging. To assure the manufacturing reliability, an inspection system of BGA is required in the surface mount process. As we can find mostly solder bridge defects, we pay attention to detecting solder bridge in a production line. The problems of image analysis for the detection of defects at BGA solder joints are the detection accuracy and image processing time according to a line speed. To get design data for the development of the inspection system, which can be used easily in the surface mount process, we attempt to measure the shape of BGA based on X-ray imaging.

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  • GAFクロミックフィルムを用いた放射線治療における線量分布測定精度に関する研究

    東 義晴, 中桐義忠, 後藤佐知子

    平成14年度〜平成15年度科学研究費補助金(基盤研究(C)(2))研究成果報告書   2004

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  • Automatic Pattern Classification of The Digitized Mammographic Breast Density

    Yoshiharu AZUMA, Sachiko GOTO, Tetsuhiro SUMIMOTO

    Cybernetics and Information Technologies, Systems and Applications   2004

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  • Detection of Defects of BGA by Tomography Imaging

    TETSUHIRO SUMIMOTO, TOSHINORI MARUYAMA, YOSHIHARU AZUMA, SACHIKO GOTO, MUNEHIRO MONDOU, NOBORU FURUKAWA AND, SABURO OKADA

    Cybernetics and Information Technologies, Systems and Applications   2004

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  • Automatic pattern classification reliability of the digitized mammographic breast density

    T Sumimoto, S Goto, Y Azuma

    Advanced Reliability Modeling   499 - 506   2004

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    The computer aided-system for the breast density pattern classification was built based on the researches of the objective quantification which converts breast density into glandular rate employing the phantom of the synthetic breast-equivalent resin material, and the subjective quantification of radiologists' visual assessment with the method of analysis of paired comparisons employing the Thurstone-Mosteller model. The system consists of the two processes. In the first process, pixels of a digitized mammogram are converted into glandular rates using the neural network to which the exposure conditions and the breast thickness were inputted. In the second process, the pattern classification and the glandular rate computation were performed taking visual assessment into consideration by the neural network to which feature values of the histogram of the glandular rate image converted into gray level were inputted. As a result of receiver operating characteristics (ROC) analysis estimating the pattern classification reliability to visual assessment in 93 samples, the area A(Z) under ROC curve was 0.95 or more values in each pattern. In the computed glandular rate to visual assessment, the maximum absolute error was 13% and the average absolute error was 3.4%.

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  • GAFクロミックフィルムを用いた放射線治療における線量分布測定精度に関する研究

    東 義晴, 中桐義忠, 後藤佐知子

    INNERVISION   2004

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  • Characteristic of GAFCHROMIC XR TYPE T dosimetry film

    14 ( 1 )   23 - 29   2003.12

  • Shape Measurement of BGA for Analysis of Defects by X-Ray Imaging

    T. Sumimoto, T. Maruyama, Y. Azuma, S. Goto, M. Mondou, N. Furukawa, S. Okada

    Instrumentation and Control Technology   2003

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  • Classification of the mammographic breast density by the histogram approach using neural networks

    Sachiko Goto, Yoshiharu Azuma, Tetsuhiro Sumimoto, Shigeru Eiho

    Instrumentation and Control Technology   2003

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  • Image Analysis Techniques for the Detection of Defectsat BGA by X-Ray

    T. Sumimoto, T. Maruyama, Y. Azuma, S. Goto, M. Mondou, N. Furukawa, S. Okada

    ADC Modeling and Testing   2003

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  • Development of image analysis for detection of defects of BGA by using x-ray images

    T Sumimoto, T Maruyama, Y Azuma, S Goto, M Mondou, N Furukawa, S Okada

    IMTC/O3: PROCEEDINGS OF THE 20TH IEEE INSTRUMENTATION AND MEASUREMENT TECHNOLOGY CONFERENCE, VOLS 1 AND 2   1131 - 1136   2003

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    Language:English   Publisher:IEEE  

    In the surface mount technology, Ball Grid Array (BGA) has been used in a production of PC boards, because of their excellent characters such as high density of the lead pin pitch, better lead rigidity and self-alignment during re-flow processing. This paper deals with the development of image analysis for the detection of defects at BGA solder joints in PC boards by using X-ray images. In the conventional IC boards, it is possible to detect defects of solder joints by visual inspection, because the lead of IC package is set on its outside. However, we can't detect visually defects at BGA solder joints, because they are hidden under the IC package. In a production line, the inspection of BGA in PC boards depends on the function test of electric circuits in the final process. To improve a cost performance and the reliability of PC boards, an inspection of BGA is required in the surface mount process. Types of defects at BGA solder joints are solder bridge, missing connection, solder voids, open connection and miss-registration of parts. As we can find mostly solder bridge in these defects, we pick up this to detect solder bridge in a production line. The problems of image analysis for the detection of defects at BGA solder joints are the detection accuracy and image processing time according to a line speed of production. To get design data for the development of the inspection system, which can be used easily in the surface mount process, it is important to develop image analysis techniques based on X-ray image data. At the first step of our study, we attempt to detect the characteristics of the solder bridges based on an image analysis.

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  • Estimation of the digitized mammographic breast density by the histogramapproach using theneural network

    Sachiko Goto, Yoshiharu Azuma, Tetsuhiro Sumimoto, Yoshihiro Takeda, Shigeru Eiho

    ADC Modeling and Testing   2003

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  • Detection of defects at BGA solder joints by using X-ray imaging

    Sumimoto Tetsuhiro, Maruyama Toshinori, Azuma Yoshiharu, Goto Sachiko, Mondou Munehiro, Furukawa Noboru, Okada Saburo

    Industrial Technology   1   191 - 196   2002

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  • Image Analysis for Detection of Defects of BGA by Using X-ray Imaging

    Sumimoto T, Maruyama T, Azuma Y, Goto S, Mondo M, Okada S

    Proceeding of International Conference on Contorol, Automation and Systems   2002

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  • A Neural Network Approach to Classification on Mammographic Density

    Goto S, Azuma Y, Sumimoto T, Eiho S

    2nd European Medical and Biological Engineering Confernce   2002

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  • Development of Measurement System for Patient Exposure Dose on X-Ray Screening Mammography

    Sachiko Goto, Yoshiharu Azuma, Tetsuhiro Sumimot, Toshinori Marnyama, Shigeru Eiho

    Proceedings of Environmental Signal Processing and Noise Controlling Techllology   2001

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  • Measurement of Patient Exposure Dose on X-Ray Screening Mammography

    Sachiko Goto, Yoshiharu Azuma, Tetsuhiro Sumimoto, Toshinori Maruyama, Shigeru Eiho

    Proceeding of the 18th IEEE Instrumentation and Measurement Technology Conference   2001

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  • Computer Assisted System for Breast Dosimetry on Mammography

    Proceedings of the 14th International Congress and Exhibition Computer Assisted Radiology and Surgery   CARS 2000 1214 1007   2000

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  • Evaluation of Breast Composition for Radiation Absorbed Dose in Mammography

    Med. Phys   Vol.27 No.6 1399   2000

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  • 診断領域X線の測定と被曝低減について

    中桐義忠, 杉田勝彦, 東義晴, 渋谷光一, 後藤佐知子

    文部省 科研費研究課題の成果   2000

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  • Evaluation of Breast Composition for Radiation Absorbed Dose in Mammography

    Med. Phys   Vol.27 No.6 1399   2000

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  • 診断領域X線の測定と被曝低減

    中桐義忠, 丸山敏則, 後藤佐知子, 東義晴, 渋谷光一, 杉田勝彦

    INNERVISION   2000

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  • Measurement of Patient Exposure Dose on X-Ray Screening Mammography

    GOTO S., AZUMA Y., SUMIMOTO T.

    IEICE technical report   100 ( 273 )   1 - 6   2000

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    Language:Japanese   Publisher:The Institute of Electronics, Information and Communication Engineers  

    This year Japanese Government has adopted mammography for the screening of breast cancer. To detect early the cancer, this method is excellent as compared with another method such as MRI and ultrasound. We have apprehension concerning exposure dose of X-ray to healthy women. Although the estimation of the exposure in the screening is done based on the Europe and American standard, it is important to make a new standard for Japanese women. In order to the estimate the exposure dose to the individual woman, we attempt to make a new system by combining the calculation method bated on the phantom and image analysis of the actual X-ray film taken at the hospital.

    CiNii Article

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  • 乳房X線撮影における医療被曝

    後藤佐知子, 東 義晴, 丸山敏則, 住本哲宏

    計測自動制御学会中国支部学術講演会論文集   2000

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  • Measurement of Patient Exposure Dose on X-Ray Screening Mammography

    GOTO S., AZUMA Y., SUMIMOTO T.

    IEICE technical report   100 ( 273 )   1 - 6   2000

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    Language:Japanese   Publisher:The Institute of Electronics, Information and Communication Engineers  

    This year Japanese Government has adopted mammography for the screening of breast cancer. To detect early the cancer, this method is excellent as compared with another method such as MRI and ultrasound. We have apprehension concerning exposure dose of X-ray to healthy women. Although the estimation of the exposure in the screening is done based on the Europe and American standard, it is important to make a new standard for Japanese women. In order to the estimate the exposure dose to the individual woman, we attempt to make a new system by combining the calculation method bated on the phantom and image analysis of the actual X-ray film taken at the hospital.

    CiNii Article

    CiNii Books

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  • 乳房X線撮影における医療被曝

    第9回計測自動制御学会中国支部学術講演会論文集   610-611   2000

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  • Evaluation of Breast Composition for Radiation Absorbed Dose in Mammography

    Med. Phys   Vol.27 No.6 1399   2000

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  • Computer Assisted System for Breast Dosimetry on Mammography

    Proceedings of the 14th International Congress and Exhibition Computer Assisted Radiology and Surgery   CARS 2000 1214 1007   2000

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  • Evaluation of Breast Composition for Radiation Absorbed Dose in Mammography

    Sachiko Goto, Yoshiharu Azuma, Toshinori Maruyam, Yoshihiro Takeda, Masami Azuma

    Medical Physics   2000

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  • Computer Assisted System for Breast Dosimetry on Mammography

    Sachiko Goto, Yoshiharu Azuma, Toshinori Maruyam, Yoshihiro Takeda, Yoshio Hiraki

    Computer Assisted Radiology and Surgery Proceedings of the 14th International Congress and Exhibition   2000

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  • Influence of the Bone for Electron-beam Therapy

    8 ( 1 )   37 - 42   1997.9

  • Clinical application of the contrast media containing soft drinks for the X-ray examination of the stomach

    6   15 - 21   1996.2

  • Physical Properties of Screen-Film Systems - New System for Chest Radiography -

    6   7 - 13   1996.2

  • Relationship between X-ray Exposure and Patient Dose on the Radiological Diagnosis

    17   63 - 70   1995.12

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  • The contrast media containing soft drinks for X-ray examination of the stomach

    5   111 - 114   1995.1

  • Statistics and analysis on the troubles of linear accelarator.

    5   99 - 103   1995.1

  • Dosimetry in Radiography

    4   69 - 73   1994.1

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Presentations

  • 第19回中四国放射線医療技術フォーラム CSFRT2023

    大畠実悠, 福井亮平, 森光祐介, 赤木憲明, 本田貢, 林藍子, 後藤佐知子

    第19回中四国放射線医療技術フォーラム CSFRT2023 

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    Event date: 2023.11.18 - 2023.11.19

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • Photon-counting CTの再構成条件がRadiomics解析に与える影響

    大畠実悠, 福井亮平, 後藤佐知子, 森光祐介, 赤木憲明, 本田貢, 平木隆夫

    日本放射線技術学会(JSRT)第51回秋季学術大会 

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    Event date: 2023.10.27 - 2023.10.29

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • Investigation of exposure parameters necessary for the depiction of microcalcification using magnification mammography

    H Yatake, T Gotanda, Y Kawaji, S Imai, T Akagawa, K Shinsho, S Goto

    IUPESM WC2022 

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    Event date: 2022.6.12 - 2022.6.17

    Language:English  

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  • CT減弱補正におけるCT撮影条件が骨SPECTの定量値に与える影響

    中澤健吾, 中嶋真大, 後藤佐知子, 竹田芳弘, 本田貢

    第17回 中四国放射線医療技術フォーラム  2021.12.18 

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    Event date: 2021.12.18 - 2021.12.19

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 高吸収体がトモシンセシス画像ノイズ測定に与える影響

    福井亮平, 太田雄大, 沼田美保, 谷口菜摘子, 西岡早紀, 松浦龍太郎, 木田勝博, 後藤佐知子, 本田貢, 平木隆夫

    第17回 中四国放射線医療技術フォーラム  2021.12.18 

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    Event date: 2021.12.18 - 2021.12.19

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • Comparison of Accuracy of Myocardial T1 Mapping Using 3D Inversion Recovery T1-weighted

    Kaito Sou, Katsuhiro Kida, Sachiko Goto

    2020.4.10 

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    Event date: 2020.4.9 - 2020.4.12

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • 3D T1 Mapping of Myocardium Using Inversion Recovery T1-weighted Turbo Field-Echo Sequence -Improving Visibility-

    Shotaro Ono, Katsuhiro Kida, Hideki Inamoto, Masahiro Terashima, Sachiko Goto, Yoshiharu

    2019.4.11 

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    Event date: 2019.4.12 - 2019.4.14

    Language:Japanese   Presentation type:Oral presentation (general)  

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  • Brief Breath-Holding for Increasing the Number of Slices in Myocardial Multi-slice T1 Mapping

    Katsuhiro Kida, Shotaro Ono, Hideki Inamoto, Masahiro Terashima, Sachiko Goto, Yoshiharu

    2019.4.13 

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    Event date: 2019.4.11 - 2019.4.14

    Language:English   Presentation type:Oral presentation (general)  

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  • Myocardial Multi-slice T1 Mapping Using Inversion Recovery T1 Turbo Field Echo (IR-T1TFE)

    Shotaro Ono, Katsuhiro Kida, Masahiro Terashima, Hideki Inamoto, Ryutaro Matsuura, Sachiko Goto

    25th European Congress of Radiology  2019.2.27 

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    Event date: 2019.2.27 - 2019.3.3

    Language:English   Presentation type:Oral presentation (general)  

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  • ワイヤ法による Digital Breast Tomosynthesis での情報伝達特性の周波数解析

    荒尾 圭子, 後藤佐知子

    第28回 日本乳癌検診学会学術総会  2018.11.23 

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    Event date: 2018.11.23 - 2018.11.24

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  • Calculation of Aortic Regurgitation Rate by Differential Analysis of Multi Location Time Enhancement Curve Using Test Injection in CT Examination

    Takuya Akagawa, Sachiko Goto, Ryutaro Mastuura, Yoshiharu Azuma

    RSNA 2017  2017.11.30 

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    Event date: 2017.11.28 - 2017.12.3

    Language:English   Presentation type:Poster presentation  

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  • T1 MAPPING FOR MYOCARDIAL MRI USING T1-WEIGHTED TURBO FIELD ECHO SEQUENCE

    Yuka Tanaka, Katsuhiro Kida, Sachiko Goto, Ryutaro Matsuura, Yumi Orihara, Yoshiharu Azuma

    SMRT 26th ANNUAL MEETING  2017.4.21 

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    Event date: 2017.4.21 - 2017.4.25

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  • Evaluation of Motion Artifact in Readout Segmented DWI with multiple b-value

    Ryutaro Matsuura, Sachiko Goto, Yumi Orihara, Yuka Tanaka, Yoshiharu Azuma

    SMRT 26th ANNUAL MEETING  2017.4.21 

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    Event date: 2017.4.21 - 2017.4.25

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  • Motion Artifact Control in Readout Segmented DWI

    Yumi Orihara, Sachiko Goto, Ryutaro Matsuura, Yuka Tanaka, Yoshiharu Azuma, Toshi Matsushita, Seiji Tahara

    SMRT 26th ANNUAL MEETING  2017.4.21 

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    Event date: 2017.4.21 - 2017.4.25

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  • Influences of Pitch Factors and Rotation Times on Response Characteristics of a Tube Current in Chest CT for Infants under a CT-Auto Exposure Control: Phantom Study

    T Akagawa, S Goto, Y Azuma

    RSNA 2016  2016.11.30 

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    Event date: 2016.11.27 - 2016.12.2

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  • A Gradient- and Spin-echo (GRASE) Sequence for Breath-hold Three-dimensional (3D) Magnetic Resonance Cholangiopancreatography (MRCP) at 3.0 T

    Katsuhiro Kida, Sachiko Goto, Ryutaro Matsuura, Yuka Tanaka, Tsutomu Kajitani, Yoshiharu Azuma

    RSNA 2016  2016.11.28 

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    Event date: 2016.11.26 - 2016.12.2

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  • Addition of DTI tractography to fMRI for hand movement

    Tomoki Ii, Katsuhiro Kida, Sachiko Goto, Ryutaro Matsuura, Tsutomu Kajitani, Yoshiharu Azuma

    SMRT 25th ANNUAL MEETING  2016.5.7 

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    Event date: 2016.5.7 - 2016.5.8

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  • Phantom Study of T1 Mapping Using Inversion Recovery Turbo Field Echo Sequence for Breast Tumor at 3.0 T

    Katsuhiro Kida, Sachiko Goto, Ryutaro Matsuura, Tomoki Ii, Tsutomu Kajitani, Yoshiharu Azuma

    SMRT 25th ANNUAL MEETING  2016.5.7 

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    Event date: 2016.5.7 - 2016.5.8

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  • Image Quality and Dose Performance in Pediatric Heart Computed Tomography Diagnosis Using a High Pitch Double Spiral Scan Technique

    Ryutaro Matsuura, Sachiko Goto, Yoshiharu Azuma, Noriaki Akagi, Tomoyuki Ii, Shuhei Sato, Seiji Tahara

    RSNA 2015  2015.12.2 

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    Event date: 2015.11.29 - 2015.12.4

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  • Scan Time Reduction for 3D TOF MR Angiography of the Brain using Single Slab at 3 T

    Katsuhiro Kida, Sachiko Goto, Ryutaro Matsuura, Tomoki Ii, Tsutomu Kajitani, Yoshiharu Azuma

    RSNA 2015  2015.11.30 

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    Event date: 2015.11.29 - 2015.12.4

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  • ファントムにおける6-point 3D radial Look-Locker法を用いたT1 mappingの検証

    Kazunori Moriya, Yoshihiko Fukukura, Katsuhiro Kida, Sachiko Goto, Yu Ueda, Kota Amou, Shigeru Shibata, Koji Yoshida, Tsutomu Tamada

    JSMRM2023  2023.9.23 

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  • Suggestion for the dose reduction of the tomosynthesis imaging by using the generated interpolation image based on the deep learning

    Ryohei Fukui, Ryutaro Matsuura, Katsuhiko Kida, Sachiko Goto

    RSNA2022  2022.11.27 

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Research Projects

  • Active learning with a chatbot positioning doll for mammography

    Grant number:19K12268  2019.04 - 2022.03

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research  Grant-in-Aid for Scientific Research (C)

    GOTO Sachiko

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    Grant amount:\3900000 ( Direct expense: \3000000 、 Indirect expense:\900000 )

    In this study, we constructed a voice dialogue system with a pseudo-personality categorized into (1) normal type and (2) anxiety complaint type by utilizing artificial brainlessness. This system is a task-oriented dialogue system, and communicates by dialogue while making state transitions with answer keywords for questions in each category. The state transition scenarios in each category were created by extracting from the website of the screening facility that publishes "Q & A" regarding "breast cancer screening". At that time, word extraction and analysis were performed as text mining, and consciousness analysis that ordinary people would have related to "mammography" was performed and classified into each category.

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  • ニューラルネットワークを用いた乳がんカテゴリーへの自動分類システムの構築

    Grant number:16790731  2004 - 2005

    日本学術振興会  科学研究費助成事業 若手研究(B)  若手研究(B)

    後藤 佐知子

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    Grant amount:\1900000 ( Direct expense: \1900000 )

    本研究は,乳房X線撮影における乳がんのカテゴリー分類を,ニューラルネットワークを用いて自動分類することを目的とする.ニューラルネットワークの構築は,放射線科専門医による主観的な,つまり経験的な判断機序を用いて試みる.最終的に,乳房X線写真からの画像情報をニューラルネットワークによって擬人化させたコンピュータ上にて分析させ,American College of Radiology (ACR)によるBreast imaging Reporting and Data System (BI-RADS)に沿った乳がんカテゴリーへの自動分類システムの構築を目指す.
    BI-RADSにおける乳がんカテゴリー分類のプロセスは以下の4段階に分けられる.
    (1)乳房全体の乳腺濃度の観察
    (2)腫瘤の有無(あれば腫瘤の大きさ,形状の観察)
    (3)石灰化陰影の有無(あればその数,分布,形状の観察)
    (4)以上を総合しカテゴリーI〜Vのリスクに分類する.
    17年度は,BI-RADSカテゴリーの自動分類をニューラルネットワークを用いて構築することを目的として研究を行った.先ず,16年度において解析した「知識」の特徴値を入力,カテゴリー分類を出力として,階層構造ニューラルネットワークを用いて初期状態の構築(プリワイヤ)を行った.その後,16年度で使用した試料画像を用い,ニューラルネットワークの学習を行った.学習方法は誤差逆伝播法を用いた.プリワイヤを学習課程において改良していき,最適条件を決定した後.最終的に構築したシステムの精度について,ニューラルネットワークの研究分野で頻繁に用いられているLeave-One-Out方法によって確認した.そして本研究において構築したシステムの有用性を分析した.

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  • Development of the dose distribution measurement equipment for Gafchromic film in radiotherapy

    Grant number:16591205  2004 - 2005

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)

    AZUMA Yoshiharu, GOTO Sachiko

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    Grant amount:\2800000 ( Direct expense: \2800000 )

    The purpose of our research is the development of inexpensive and high-speed measurement equipment for the improvement of dose distribution measurement accuracy of Gafchromic film in high energy x-rays. First, the measurement light source of the transmission unit of a general-purpose flat-bed scanner, ES-2200 (EPSON) was converted into the wavelength of 670 nm for Gafchromic film MD-55 and HS in 2005. Moreover, since EBT model was also put on the market in addition to Gafchromic film MD-55 and HS, the transmission unit of measurement wavelength 630 nm is ordered. Performance evaluation of the scanner to Gafchromic film MD-55, HS and EBT was performed. The outline of the result is summarized to below.
    1. Match to the measurement light source wavelength of the scanner to Gafchromic films
    Gafchromic film MD-55 and HS have the absorption spectrum with a maximum absorption band centered at 670 nm and Gafchromic film EBT has the absorption spectrum with a maximum absorption band centered at 636 run. For two wavelengths, the form that consists of one body of a general-purpose flat-bed scanner and two exchange transmission units with different measurement LED light source was chosen. Thereby, the inexpensive scanner of a multiple use way has been realized.
    2. Improvement in measurement sensitivity
    From having adjusted to the measurement light source with the maximum absorption wavelength to each Gafchromic film, the density measurement system of high sensitivity of 1.5-1.8 was able to be completed as compared with use of the conventional general-purpose flat-bed scanner. Furthermore, when performing the measure against a noise well, it became possible to raise measurement accuracy.

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  • Study on the dose distribution measurement precision in the radiotherapy using GAFchromic film

    Grant number:14570859  2002 - 2003

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)

    AZUMA Yoshiharu, GOTO Sachiko, NAKAGIRI Yoshitada

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    Grant amount:\1900000 ( Direct expense: \1900000 )

    In the radiotherapy field, a complicated dose distribution must be evaluated and it is required that dose assessment should have the high precision. As the radiometer that performs dose distribution assessment of 2-dimensional one, Radiochromic film is developed and attracts attention. The density ununiformity of the film and the matching with the film and a density-measuring instrument are directly involved in a measurement error directly. Then, while investigating about the ununiformity of the density of the film in this study, the influence, which the optical density before irradiation has on the density after irradiation, was analyzed, and the correction procedure of he influence was considered. First, to dosimetry system, which consists of Laser Densitometer Model 1710 for an x-ray film and Gafchromic film MD-55-2, the check of density measurement precision was performed and the existence of the artifact by the formation, of a 2-dimensional picture of density data was observed in 1-60 Gy. Consequently, in case where the measurement precision in highly detailed pixel level is required, such as performing complicated dose distribution assessment in 3D-CRT or IMRT, it was thought to be necessary to add further the correction process of density ununiformity that is represented by double exposure technique. Furthermore, it turned out that the sample pixel value after irradiation also becomes high as the sample pixel value before irradiation became high. Moreover, since the linear approximation, was possible in the relation between both sample pixel values, the procedure of creating conversion curve of an absorbed dose to a pixel value for every sample pixel value before each irradiation, and correcting the sample pixel value after irradiation was adopted. By this procedure, the measurement result higher than the measurement performed only with the conventional conversion curve of an absorbed dose to a pixel value for precision could be obtained.

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  • 乳癌検診における医療被曝と受診効率の推定

    Grant number:12770489  2000 - 2001

    日本学術振興会  科学研究費助成事業 奨励研究(A)  奨励研究(A)

    後藤 佐知子

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    Grant amount:\1300000 ( Direct expense: \1300000 )

    乳癌は乳腺に限局して発生する癌であるため,X線マンモグラフィにおける医療被曝は乳腺組織に吸収された平均線量で表すのが,最も有効な被曝線量の指標となる.すなわち,乳腺組織量の多少によって医療被曝は左右されることになる.乳腺組織量は個人差の最も大きい臓器であり,また同一個人であっても年齢を重ねる事によって千差万別に変化していく.そこで本研究は,乳腺組織量の多少に関係すると思われる要因,年齢,乳房厚,出産回数,授乳歴,ホルモン療法の既往歴別にX線マンモグラフィ受診者の医療被曝をデータベース化し,被曝(リスク)と早期発見(利益)についての妥当性を検討した.結果,乳腺量に影響を及ぼす最大の要因は加齢であった.また,ホルモン療法の既往歴は,個人によっては治療後,かなりの期間が経っても組織の乳腺様化が持続し,加齢による要因に負の影響を与えた.出産回数では,回数別では大きな差は見られなかったが,出産0回,未出産については高齢でも高い乳腺組織量を保っていた.授乳歴では,同一個人における乳腺量の左右差に大きな影響を与えた.X線マンモグラフィを用いた乳がん検診のリスク・利益分析についての先行研究では,リスクを寿命の短縮とした上で,利益とのバランス関係が成立するのは約30歳としている.しかし,30歳の乳腺組織量は出産の有無に関係なく非常に多く,乳房厚も厚いため医療被曝は多くなる.その反面,X線マンモグラフィの診断的価値はかなり低いものとなる場合が多い.本研究では,リスクを医療被曝,利益を早期発見(診断的価値)として統計的分析をニューラルネットワークにて行った結果,バランス関係は約45歳と考えられた.

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  • X線マンモグラフィの被曝線量の測定と低減

    Grant number:10770445  1998 - 1999

    日本学術振興会  科学研究費助成事業 奨励研究(A)  奨励研究(A)

    後藤 佐知子

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    Grant amount:\1300000 ( Direct expense: \1300000 )

    X線マンモグラフィにおける医療被曝の測定及び低減を目的として,平成11年度は以下の調査,研究を行った.
    まず,医療被曝を推定するために,平成10年度で得られたデータベースから以下のルックアップテーブルを作成した.
    1.乳房組織構成比別(乳腺:脂肪組織)の平均乳腺組織線量
    2.空中における入射線量
    3.乳房組織構成比別のディジタル値
    以上のルックアップテーブルにX線マンモグラフィにおける撮影条件を参照させ,マンモグラフィをディジタイズする事により,患者の医療被曝を推定できるシステムを完成した.そして以下のような検討・考察を行った.
    1.本システムにより,日本人女性における乳房組織構成比の妥当性
    2.平成10年度に行ったアンケート調査と,乳房組織構成比の相関
    3.実際の臨床における平均乳腺組織線量の推定
    4.X線マンモグラフィでのガイドラインと,3.の比較,および限度値低減の可能性
    本研究の結果より,平均的な日本人女性の乳房は欧米人に比べ乳腺組織が多い傾向にある事が分かった.従って,欧米人を対象として作成されたガイドラインをそのまま参照する事は,医療被曝を過小評価する危険性をもたらす.また,高年齢,出産回数,授乳状況,婦人科などにおけるホルモン療法によって乳房構成比は大きく異なり,負の相関がある事がわかった.すなわち,乳房構成を一律に想定し(乳腺50%:脂肪組織50%),X線装置の撮影条件のみで算出する従来の医療被曝推定法では,患者の個人被曝を推定するには不十分であると思われた.

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  • Dosimetry of Patient Dose and the reduction in radiological diagnosis

    Grant number:09670935  1997 - 1999

    Japan Society for the Promotion of Science  Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C)  Grant-in-Aid for Scientific Research (C)

    NAKAGIRI Yoshitada, SHIBUYA Koichi, AZUMA Yoshiharu, SUGITA Katsuhiko, GOTO Sachiko

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    Grant amount:\1000000 ( Direct expense: \1000000 )

    Surface dose and PDD data were measured to determine the degree of radiological exposure in different organs in patients undergoing an X-ray examination. Through these of these data, the degree of radiological exposure to any particular organ in the body can be estimated. A survey of radiological conditions was conducted at a hospital in Okayama Prefecture to determine the degree of fetal exposure in pregnant women undergoing a plain abdominal X-ray examination. The results demonstrated that the degree of exposure varied greatly from one fetus to the next. Also, based on the mean radiological exposure, it was determined that 164 X-ray examinations would equal the threshold value of the biological tolerance of human fetuses.
    Furthermore, plain X-rays were taken from the lateral side of the lumbar region to investigate the effect of bone tissue on fetal exposure. The results revealed that the degree of radiological fetal exposure was affected by the presence of bone tissue, but this effect was negligibly detectable when a fetus was at least 10 cm away from the bone tissue.
    In terms of measures to reduce radiological exposure, shifts in PDD were analyzed by attaching an added filter to the outlet to increase total filtration. The results demonstrated that the degree of reduction in radiation dose for deep areas of the body was smaller than that for surface areas, and that the tendency was that the higher X-ray tube voltage or the thinner the filter, the smaller the rate of reduction.
    As the results, patient dose in radiological diagnosis was smaller than that in giving rise to the acute biological damages, but radiologists or radiological technologists must cooperate to minimize patient exposure in X-ray examinations.

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